The different techniques that enable drug delivery in the desired manner are constantly investigated and developed to enhance patient compliance and drug efficiency and to reduce the side effects of drugs. One of the key problems in designing appropriate formulation for drug delivery is the right selection of excipient. Among many different materials, gellan gum as a microbially derived polysaccharide is nowadays drawing increased attention because of its favorable physicochemical, mechanical, and functional properties. Its abundance, nontoxicity, easy gelation, mucoadhesiveness, thermal and acid stability, high transparency, etc. have made gellan gum to be applied in many different dosage forms (gels, as mucoadhesive or granulating agent, tablet binder, in controlled release dosage forms, for production of beads, films, microspheres and microcapsules, nanohydrogels, nanoparticles, etc.) and for different routes of administration (oral, ophthalmic, nasal, topical, etc.). This chapter i...s focused on recent advances related to the applications, research, and development of different uses of gellan gum in drug delivery.
TY - CHAP
AU - Milivojević, Milan
AU - Pajić-Lijaković, Ivana
AU - Bugarski, Branko
AU - Nayak, A.K.
AU - Hasnain, M.S.
PY - 2019
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4204
AB - The different techniques that enable drug delivery in the desired manner are constantly investigated and developed to enhance patient compliance and drug efficiency and to reduce the side effects of drugs. One of the key problems in designing appropriate formulation for drug delivery is the right selection of excipient. Among many different materials, gellan gum as a microbially derived polysaccharide is nowadays drawing increased attention because of its favorable physicochemical, mechanical, and functional properties. Its abundance, nontoxicity, easy gelation, mucoadhesiveness, thermal and acid stability, high transparency, etc. have made gellan gum to be applied in many different dosage forms (gels, as mucoadhesive or granulating agent, tablet binder, in controlled release dosage forms, for production of beads, films, microspheres and microcapsules, nanohydrogels, nanoparticles, etc.) and for different routes of administration (oral, ophthalmic, nasal, topical, etc.). This chapter is focused on recent advances related to the applications, research, and development of different uses of gellan gum in drug delivery.
T2 - Natural Polysaccharides in Drug Delivery and Biomedical Applications
T1 - Gellan gum in drug delivery applications
EP - 186
SP - 145
DO - 10.1016/B978-0-12-817055-7.00006-6
ER -
@inbook{
author = "Milivojević, Milan and Pajić-Lijaković, Ivana and Bugarski, Branko and Nayak, A.K. and Hasnain, M.S.",
year = "2019",
abstract = "The different techniques that enable drug delivery in the desired manner are constantly investigated and developed to enhance patient compliance and drug efficiency and to reduce the side effects of drugs. One of the key problems in designing appropriate formulation for drug delivery is the right selection of excipient. Among many different materials, gellan gum as a microbially derived polysaccharide is nowadays drawing increased attention because of its favorable physicochemical, mechanical, and functional properties. Its abundance, nontoxicity, easy gelation, mucoadhesiveness, thermal and acid stability, high transparency, etc. have made gellan gum to be applied in many different dosage forms (gels, as mucoadhesive or granulating agent, tablet binder, in controlled release dosage forms, for production of beads, films, microspheres and microcapsules, nanohydrogels, nanoparticles, etc.) and for different routes of administration (oral, ophthalmic, nasal, topical, etc.). This chapter is focused on recent advances related to the applications, research, and development of different uses of gellan gum in drug delivery.",
journal = "Natural Polysaccharides in Drug Delivery and Biomedical Applications",
booktitle = "Gellan gum in drug delivery applications",
pages = "186-145",
doi = "10.1016/B978-0-12-817055-7.00006-6"
}
Milivojević, M., Pajić-Lijaković, I., Bugarski, B., Nayak, A.K.,& Hasnain, M.S.. (2019). Gellan gum in drug delivery applications. in Natural Polysaccharides in Drug Delivery and Biomedical Applications, 145-186.
https://doi.org/10.1016/B978-0-12-817055-7.00006-6
Milivojević M, Pajić-Lijaković I, Bugarski B, Nayak A, Hasnain M. Gellan gum in drug delivery applications. in Natural Polysaccharides in Drug Delivery and Biomedical Applications. 2019;:145-186.
doi:10.1016/B978-0-12-817055-7.00006-6 .
Milivojević, Milan, Pajić-Lijaković, Ivana, Bugarski, Branko, Nayak, A.K., Hasnain, M.S., "Gellan gum in drug delivery applications" in Natural Polysaccharides in Drug Delivery and Biomedical Applications (2019):145-186,
https://doi.org/10.1016/B978-0-12-817055-7.00006-6 . .
