The chromatographic behavior of newly synthesized para-substituted propanoic acid amides has been studied in normal- and reversed-phase thin-layer chromatography. The retention mechanism on different TLC supports was investigated. The retention constants determined for the amides are discussed in terms of the physicochernical properties of the solute and the stationary and mobile phases. R-M,R-w, derived by extrapolation from retention in reversed-phase chromatography, was correlated with hydrophobic parameters pi and log P, calculated by the Rekker fragmental method and by use of the commercial program ACD/log P.
Keywords:
propanoic acid amides / TLC / normal and reversed-phase chromatography / lipophilicity
Source:
JPC-Journal of Planar Chromatography-Modern Tlc, 2002, 15, 4, 274-279
TY - JOUR
AU - Đaković-Sekulić, Tatjana
AU - Perišić-Janjić, Nada
AU - Petrović, Slobodan
PY - 2002
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/425
AB - The chromatographic behavior of newly synthesized para-substituted propanoic acid amides has been studied in normal- and reversed-phase thin-layer chromatography. The retention mechanism on different TLC supports was investigated. The retention constants determined for the amides are discussed in terms of the physicochernical properties of the solute and the stationary and mobile phases. R-M,R-w, derived by extrapolation from retention in reversed-phase chromatography, was correlated with hydrophobic parameters pi and log P, calculated by the Rekker fragmental method and by use of the commercial program ACD/log P.
PB - Springer Heidelberg, Heidelberg
T2 - JPC-Journal of Planar Chromatography-Modern Tlc
T1 - Normal- and reversed-phase chromatography of para-substituted propanoic acid Amides
EP - 279
IS - 4
SP - 274
VL - 15
DO - 10.1556/JPC.15.2002.4.6
ER -
@article{
author = "Đaković-Sekulić, Tatjana and Perišić-Janjić, Nada and Petrović, Slobodan",
year = "2002",
abstract = "The chromatographic behavior of newly synthesized para-substituted propanoic acid amides has been studied in normal- and reversed-phase thin-layer chromatography. The retention mechanism on different TLC supports was investigated. The retention constants determined for the amides are discussed in terms of the physicochernical properties of the solute and the stationary and mobile phases. R-M,R-w, derived by extrapolation from retention in reversed-phase chromatography, was correlated with hydrophobic parameters pi and log P, calculated by the Rekker fragmental method and by use of the commercial program ACD/log P.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "JPC-Journal of Planar Chromatography-Modern Tlc",
title = "Normal- and reversed-phase chromatography of para-substituted propanoic acid Amides",
pages = "279-274",
number = "4",
volume = "15",
doi = "10.1556/JPC.15.2002.4.6"
}
Đaković-Sekulić, T., Perišić-Janjić, N.,& Petrović, S.. (2002). Normal- and reversed-phase chromatography of para-substituted propanoic acid Amides. in JPC-Journal of Planar Chromatography-Modern Tlc
Springer Heidelberg, Heidelberg., 15(4), 274-279.
https://doi.org/10.1556/JPC.15.2002.4.6
Đaković-Sekulić T, Perišić-Janjić N, Petrović S. Normal- and reversed-phase chromatography of para-substituted propanoic acid Amides. in JPC-Journal of Planar Chromatography-Modern Tlc. 2002;15(4):274-279.
doi:10.1556/JPC.15.2002.4.6 .
Đaković-Sekulić, Tatjana, Perišić-Janjić, Nada, Petrović, Slobodan, "Normal- and reversed-phase chromatography of para-substituted propanoic acid Amides" in JPC-Journal of Planar Chromatography-Modern Tlc, 15, no. 4 (2002):274-279,
https://doi.org/10.1556/JPC.15.2002.4.6 . .
