Glycoderivatives are an important class of molecules with enormous relevance in numerous biological phenomena; therefore, they have a key role in the learning, understanding, and assessment of different diseases. Nanotechnology, and in particular the design of new nanomaterials, is one of the areas of greatest interest today. In this case, graphene nanomaterials represent very interesting platforms for studying glycosystems, glyconanomaterials that combine the biomolecular recognition and the characteristics of nanoscale objects in the development of early diagnosis systems, and efficient specific therapeutic modalities. In this mini-review, we discuss some results recently described in the literature on the conjugation of graphene materials and carbohydrates through the selective interaction of glycoenzymes in graphene to create new materials with biosensing applications, the development and application of sugar-graphene composites, and finally biosystems combining the properties of g...raphene with metallic nanoparticles and sugars for the creation of excellent glyconanomaterials as novel systems for the therapy or diagnosis of important diseases such as cancer or diabetes.
Source:
ACS Omega, 2020, 5, 9, 4362-4369
Publisher:
Amer Chemical Soc, Washington
Funding / projects:
Spanish GovernmentSpanish Government
Spanish National Research Council (CSIC)Consejo Superior de Investigaciones Cientificas (CSIC)
TY - JOUR
AU - Losada-Garcia, Noelia
AU - Rodriguez-Oliva, Ivan
AU - Simović, Milica
AU - Bezbradica, Dejan
AU - Palomo, Jose M.
PY - 2020
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4486
AB - Glycoderivatives are an important class of molecules with enormous relevance in numerous biological phenomena; therefore, they have a key role in the learning, understanding, and assessment of different diseases. Nanotechnology, and in particular the design of new nanomaterials, is one of the areas of greatest interest today. In this case, graphene nanomaterials represent very interesting platforms for studying glycosystems, glyconanomaterials that combine the biomolecular recognition and the characteristics of nanoscale objects in the development of early diagnosis systems, and efficient specific therapeutic modalities. In this mini-review, we discuss some results recently described in the literature on the conjugation of graphene materials and carbohydrates through the selective interaction of glycoenzymes in graphene to create new materials with biosensing applications, the development and application of sugar-graphene composites, and finally biosystems combining the properties of graphene with metallic nanoparticles and sugars for the creation of excellent glyconanomaterials as novel systems for the therapy or diagnosis of important diseases such as cancer or diabetes.
PB - Amer Chemical Soc, Washington
T2 - ACS Omega
T1 - New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis
EP - 4369
IS - 9
SP - 4362
VL - 5
DO - 10.1021/acsomega.9b04332
ER -
@article{
author = "Losada-Garcia, Noelia and Rodriguez-Oliva, Ivan and Simović, Milica and Bezbradica, Dejan and Palomo, Jose M.",
year = "2020",
abstract = "Glycoderivatives are an important class of molecules with enormous relevance in numerous biological phenomena; therefore, they have a key role in the learning, understanding, and assessment of different diseases. Nanotechnology, and in particular the design of new nanomaterials, is one of the areas of greatest interest today. In this case, graphene nanomaterials represent very interesting platforms for studying glycosystems, glyconanomaterials that combine the biomolecular recognition and the characteristics of nanoscale objects in the development of early diagnosis systems, and efficient specific therapeutic modalities. In this mini-review, we discuss some results recently described in the literature on the conjugation of graphene materials and carbohydrates through the selective interaction of glycoenzymes in graphene to create new materials with biosensing applications, the development and application of sugar-graphene composites, and finally biosystems combining the properties of graphene with metallic nanoparticles and sugars for the creation of excellent glyconanomaterials as novel systems for the therapy or diagnosis of important diseases such as cancer or diabetes.",
publisher = "Amer Chemical Soc, Washington",
journal = "ACS Omega",
title = "New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis",
pages = "4369-4362",
number = "9",
volume = "5",
doi = "10.1021/acsomega.9b04332"
}
Losada-Garcia, N., Rodriguez-Oliva, I., Simović, M., Bezbradica, D.,& Palomo, J. M.. (2020). New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis. in ACS Omega
Amer Chemical Soc, Washington., 5(9), 4362-4369.
https://doi.org/10.1021/acsomega.9b04332
Losada-Garcia N, Rodriguez-Oliva I, Simović M, Bezbradica D, Palomo JM. New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis. in ACS Omega. 2020;5(9):4362-4369.
doi:10.1021/acsomega.9b04332 .
Losada-Garcia, Noelia, Rodriguez-Oliva, Ivan, Simović, Milica, Bezbradica, Dejan, Palomo, Jose M., "New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis" in ACS Omega, 5, no. 9 (2020):4362-4369,
https://doi.org/10.1021/acsomega.9b04332 . .
