Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine

Lazić, Anita

Sinteza, struktura i svojstva potencijalno biološki aktivnih derivata cikloalkanspiro-5-hidantoina

Doctoral thesis (Published version)

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Abstract

In order to examine solvation effects on the pharmacological properties of hydantoin derivatives, three series of compounds have been synthesized: 3-(4-substituted benzyl)cyclopentanespiro-5-hydantoins, 3-(4-substituted benzyl) cycloheхanespiro-5-hydantoins, and 3-(4-substituted benzyl) cycloheptanespiro-5- -hydantoins...

U okviru proučavanja odnosa strukture i biološke aktivnosti derivata cikloalkanspiro-5-hidantoina, u ovom radu su sintetisane tri nove serije jedinjenja i to: 3-(4-supstituisani benzil)ciklopentanspiro-5-hidantoini, 3-(4-supstituisani benzil)cikloheksanspiro-5-hidantoini i 3-(4-supstituisani benzil)cikloheptanspiro-5-hidantoini...

Keywords:

Spirohydantoins / Solvatochromism / The crystal structure / DFT calculation / Antiproliferative activity / Спирохидантоини / Солватохромизам / Кристална структура / DFT прорачу / Антипролиферативна активност

Source:
2017

Publisher:

Univerzitet u Beogradu, Tehnološko-metalurški fakultet

Funding / projects:

Study of the Synthesis, Structure and Activity of Natural and Synthetic Organic Compounds (RS-172013)

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Handle

https://hdl.handle.net/21.15107/rcub_technorep_4662

URI

http://eteze.bg.ac.rs/application/showtheses?thesesId=5661
https://fedorabg.bg.ac.rs/fedora/get/o:17309/bdef:Content/download
http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49914383
http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4662

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Institution/Community

Tehnološko-metalurški fakultet

TY  - THES
AU  - Lazić, Anita
PY  - 2017
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=5661
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:17309/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49914383
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4662
AB  - In order to examine solvation effects on the pharmacological properties of hydantoin derivatives, three series of compounds have been synthesized: 3-(4-substituted benzyl)cyclopentanespiro-5-hydantoins, 3-(4-substituted benzyl) cycloheхanespiro-5-hydantoins, and 3-(4-substituted benzyl) cycloheptanespiro-5- -hydantoins...
AB  - U okviru proučavanja odnosa strukture i biološke aktivnosti derivata cikloalkanspiro-5-hidantoina, u ovom radu su sintetisane tri nove serije jedinjenja i to: 3-(4-supstituisani benzil)ciklopentanspiro-5-hidantoini, 3-(4-supstituisani benzil)cikloheksanspiro-5-hidantoini i 3-(4-supstituisani benzil)cikloheptanspiro-5-hidantoini...
PB  - Univerzitet u Beogradu, Tehnološko-metalurški fakultet
T1  - Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine
T1  - Sinteza, struktura i svojstva potencijalno biološki aktivnih derivata cikloalkanspiro-5-hidantoina
UR  - https://hdl.handle.net/21.15107/rcub_technorep_4662
ER  -

@phdthesis{
author = "Lazić, Anita",
year = "2017",
abstract = "In order to examine solvation effects on the pharmacological properties of hydantoin derivatives, three series of compounds have been synthesized: 3-(4-substituted benzyl)cyclopentanespiro-5-hydantoins, 3-(4-substituted benzyl) cycloheхanespiro-5-hydantoins, and 3-(4-substituted benzyl) cycloheptanespiro-5- -hydantoins..., U okviru proučavanja odnosa strukture i biološke aktivnosti derivata cikloalkanspiro-5-hidantoina, u ovom radu su sintetisane tri nove serije jedinjenja i to: 3-(4-supstituisani benzil)ciklopentanspiro-5-hidantoini, 3-(4-supstituisani benzil)cikloheksanspiro-5-hidantoini i 3-(4-supstituisani benzil)cikloheptanspiro-5-hidantoini...",
publisher = "Univerzitet u Beogradu, Tehnološko-metalurški fakultet",
title = "Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine, Sinteza, struktura i svojstva potencijalno biološki aktivnih derivata cikloalkanspiro-5-hidantoina",
url = "https://hdl.handle.net/21.15107/rcub_technorep_4662"
}

Lazić, A.. (2017). Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine. 
Univerzitet u Beogradu, Tehnološko-metalurški fakultet..
https://hdl.handle.net/21.15107/rcub_technorep_4662

Lazić A. Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine. 2017;.
https://hdl.handle.net/21.15107/rcub_technorep_4662 .

Lazić, Anita, "Synthesis, structure and properties of potentially biologically active derivatives of cycloalkanespiro-5- -hydantoine" (2017),
https://hdl.handle.net/21.15107/rcub_technorep_4662 .