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Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts

Optimizacija procesa ekstrakcije herbe Thymus serpyllum L., biološke aktivnosti i inkapsulacija ekstrakata

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2018
4666.pdf (2.022Mb)
Authors
Jovanović, Aleksandra
Contributors
Bugarski, Branko
Knežević-Jugović, Zorica
Šavikin, Katarina
Zdunić, Gordana
Đorđević, Verica
Doctoral thesis (Published version)
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Abstract
Thymus serpyllum L. (Lamiaceae), well-known as wild thyme, is a perennial subshrub, abundant in polyphenols compounds, which possess antioxidant, antimicrobial, antihypertensive, antispasmodic, antiinflammatory, anticarcinogenic, anti-allergic and anxiolytic properties. The optimization of extraction represents the first step in obtaining the maximum yield of active compounds from plant sources, which are safe and natural alternative to synthetic components. Polyphenols instability during food processing, distribution or storage, and in the gastrointestinal tract, limits their activity and potential health benefits. The encapsulation of polyphenols can overcome the drawbacks of their instability, alleviate unpleasant tastes or flavors, and improve the bioavailability and half-life of the compounds...
Vrsta Thymus serpyllum L. (Lamiaceae) ili majčina dušica predstavlja višegodišnju zeljastu biljku bogatu polifenolima koji pokazuju antioksidativni, antimikrobni, antihipertenzivni, spazmolitični, antiinflamatorni, antikancerogeni, antialergijski i anksiolitični efekat. Optimizacija procesa ekstrakcije predstavlja prvi korak u dobijanju maksimalnog prinosa aktivnih principa iz biljnih izvora kao bezbedne i prirodne alternative sintetskim komponentama. Nestabilnost polifenola u toku procesa proizvodnje, distribucije i čuvanja namirnica, kao i u uslovima gastrointestinalnog trakta, ograničava njihovu aktivnost i potencijalne korisne efekte na zdravlje ljudi. Inkapsulacija polifenola dovodi do prevazilaženja pomenutih nedostataka, ublažavanja gorkog ukusa polifenola i poboljšanja njihove bioraspoloživosti i poluvremena eliminacije...
Keywords:
Thymus serpyllum / polyphenols / optimization of extraction / chemical characterization / biological activity / encapsulation / Thymus serpyllum / полифеноли / оптимизација процеса екстракције / хемијска карактеризација / биолошка активност / инкапсулација
Source:
2018
Publisher:
  • Univerzitet u Beogradu, Tehnološko-metalurški fakultet
Funding / projects:
  • Novel encapsulation and enzyme technologies for designing of new biocatalysts and biologically active compounds targeting enhancement of food quality, safety and competitiveness (RS-46010)
  • Traditional and new products of cultivated and wild growing fruits and grape vines, and by-products durring processing, with special emphasis on indigenous varieties: chemical characterization and biological profile (RS-46013)
[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_technorep_4669
URI
http://eteze.bg.ac.rs/application/showtheses?thesesId=5732
https://fedorabg.bg.ac.rs/fedora/get/o:17554/bdef:Content/download
http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49968143
http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4669
Collections
  • Doktorske disertacije
Institution/Community
Tehnološko-metalurški fakultet
TY  - THES
AU  - Jovanović, Aleksandra
PY  - 2018
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=5732
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:17554/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49968143
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4669
AB  - Thymus serpyllum L. (Lamiaceae), well-known as wild thyme, is a perennial subshrub, abundant in polyphenols compounds, which possess antioxidant, antimicrobial, antihypertensive, antispasmodic, antiinflammatory, anticarcinogenic, anti-allergic and anxiolytic properties. The optimization of extraction represents the first step in obtaining the maximum yield of active compounds from plant sources, which are safe and natural alternative to synthetic components. Polyphenols instability during food processing, distribution or storage, and in the gastrointestinal tract, limits their activity and potential health benefits. The encapsulation of polyphenols can overcome the drawbacks of their instability, alleviate unpleasant tastes or flavors, and improve the bioavailability and half-life of the compounds...
AB  - Vrsta Thymus serpyllum L. (Lamiaceae) ili majčina dušica predstavlja višegodišnju zeljastu biljku bogatu polifenolima koji pokazuju antioksidativni, antimikrobni, antihipertenzivni, spazmolitični, antiinflamatorni, antikancerogeni, antialergijski i anksiolitični efekat. Optimizacija procesa ekstrakcije predstavlja prvi korak u dobijanju maksimalnog prinosa aktivnih principa iz biljnih izvora kao bezbedne i prirodne alternative sintetskim komponentama. Nestabilnost polifenola u toku procesa proizvodnje, distribucije i čuvanja namirnica, kao i u uslovima gastrointestinalnog trakta, ograničava njihovu aktivnost i potencijalne korisne efekte na zdravlje ljudi. Inkapsulacija polifenola dovodi do prevazilaženja pomenutih nedostataka, ublažavanja gorkog ukusa polifenola i poboljšanja njihove bioraspoloživosti i poluvremena eliminacije...
PB  - Univerzitet u Beogradu, Tehnološko-metalurški fakultet
T1  - Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts
T1  - Optimizacija procesa ekstrakcije herbe Thymus serpyllum L., biološke aktivnosti i inkapsulacija ekstrakata
UR  - https://hdl.handle.net/21.15107/rcub_technorep_4669
ER  - 
@phdthesis{
author = "Jovanović, Aleksandra",
year = "2018",
abstract = "Thymus serpyllum L. (Lamiaceae), well-known as wild thyme, is a perennial subshrub, abundant in polyphenols compounds, which possess antioxidant, antimicrobial, antihypertensive, antispasmodic, antiinflammatory, anticarcinogenic, anti-allergic and anxiolytic properties. The optimization of extraction represents the first step in obtaining the maximum yield of active compounds from plant sources, which are safe and natural alternative to synthetic components. Polyphenols instability during food processing, distribution or storage, and in the gastrointestinal tract, limits their activity and potential health benefits. The encapsulation of polyphenols can overcome the drawbacks of their instability, alleviate unpleasant tastes or flavors, and improve the bioavailability and half-life of the compounds..., Vrsta Thymus serpyllum L. (Lamiaceae) ili majčina dušica predstavlja višegodišnju zeljastu biljku bogatu polifenolima koji pokazuju antioksidativni, antimikrobni, antihipertenzivni, spazmolitični, antiinflamatorni, antikancerogeni, antialergijski i anksiolitični efekat. Optimizacija procesa ekstrakcije predstavlja prvi korak u dobijanju maksimalnog prinosa aktivnih principa iz biljnih izvora kao bezbedne i prirodne alternative sintetskim komponentama. Nestabilnost polifenola u toku procesa proizvodnje, distribucije i čuvanja namirnica, kao i u uslovima gastrointestinalnog trakta, ograničava njihovu aktivnost i potencijalne korisne efekte na zdravlje ljudi. Inkapsulacija polifenola dovodi do prevazilaženja pomenutih nedostataka, ublažavanja gorkog ukusa polifenola i poboljšanja njihove bioraspoloživosti i poluvremena eliminacije...",
publisher = "Univerzitet u Beogradu, Tehnološko-metalurški fakultet",
title = "Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts, Optimizacija procesa ekstrakcije herbe Thymus serpyllum L., biološke aktivnosti i inkapsulacija ekstrakata",
url = "https://hdl.handle.net/21.15107/rcub_technorep_4669"
}
Jovanović, A.. (2018). Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts. 
Univerzitet u Beogradu, Tehnološko-metalurški fakultet..
https://hdl.handle.net/21.15107/rcub_technorep_4669
Jovanović A. Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts. 2018;.
https://hdl.handle.net/21.15107/rcub_technorep_4669 .
Jovanović, Aleksandra, "Optimization of the extraction process from Thymus serpyllum L. herb, biological activities and encapsulation of extracts" (2018),
https://hdl.handle.net/21.15107/rcub_technorep_4669 .

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