Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte
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2021
Authors
Dimitrijevic, Silvana B.Alagic, Sladana
Pavlovic, Sonja
Stankovic, Biljana
Kotur, Nikola
Ivanovic, Aleksandra
Dimitrijević, Stevan

Article (Published version)

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The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.
Keywords:
Gold-plating / Cytotoxicity / Mercaptotriazole / Cyanide bath / Non-cyanide electrolyteSource:
Journal of the Indian Chemical Society, 2021, 98, 11Funding / projects:
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200135 (University of Belgrade, Faculty of Technology and Metallurgy) (RS-200135)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200052 (Mining and Metallurgy Institute, Bor) (RS-200052)
DOI: 10.1016/j.jics.2021.100219
ISSN: 0019-4522
WoS: 000730639100047
Scopus: 2-s2.0-85118751911
Institution/Community
Inovacioni centarTY - JOUR AU - Dimitrijevic, Silvana B. AU - Alagic, Sladana AU - Pavlovic, Sonja AU - Stankovic, Biljana AU - Kotur, Nikola AU - Ivanovic, Aleksandra AU - Dimitrijević, Stevan PY - 2021 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4822 AB - The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period. T2 - Journal of the Indian Chemical Society T1 - Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte IS - 11 VL - 98 DO - 10.1016/j.jics.2021.100219 ER -
@article{ author = "Dimitrijevic, Silvana B. and Alagic, Sladana and Pavlovic, Sonja and Stankovic, Biljana and Kotur, Nikola and Ivanovic, Aleksandra and Dimitrijević, Stevan", year = "2021", abstract = "The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.", journal = "Journal of the Indian Chemical Society", title = "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte", number = "11", volume = "98", doi = "10.1016/j.jics.2021.100219" }
Dimitrijevic, S. B., Alagic, S., Pavlovic, S., Stankovic, B., Kotur, N., Ivanovic, A.,& Dimitrijević, S.. (2021). Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society, 98(11). https://doi.org/10.1016/j.jics.2021.100219
Dimitrijevic SB, Alagic S, Pavlovic S, Stankovic B, Kotur N, Ivanovic A, Dimitrijević S. Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society. 2021;98(11). doi:10.1016/j.jics.2021.100219 .
Dimitrijevic, Silvana B., Alagic, Sladana, Pavlovic, Sonja, Stankovic, Biljana, Kotur, Nikola, Ivanovic, Aleksandra, Dimitrijević, Stevan, "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte" in Journal of the Indian Chemical Society, 98, no. 11 (2021), https://doi.org/10.1016/j.jics.2021.100219 . .