The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.
TY - JOUR
AU - Dimitrijevic, Silvana B.
AU - Alagic, Sladana
AU - Pavlovic, Sonja
AU - Stankovic, Biljana
AU - Kotur, Nikola
AU - Ivanovic, Aleksandra
AU - Dimitrijević, Stevan
PY - 2021
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4822
AB - The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.
T2 - Journal of the Indian Chemical Society
T1 - Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte
IS - 11
VL - 98
DO - 10.1016/j.jics.2021.100219
ER -
@article{
author = "Dimitrijevic, Silvana B. and Alagic, Sladana and Pavlovic, Sonja and Stankovic, Biljana and Kotur, Nikola and Ivanovic, Aleksandra and Dimitrijević, Stevan",
year = "2021",
abstract = "The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.",
journal = "Journal of the Indian Chemical Society",
title = "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte",
number = "11",
volume = "98",
doi = "10.1016/j.jics.2021.100219"
}
Dimitrijevic, S. B., Alagic, S., Pavlovic, S., Stankovic, B., Kotur, N., Ivanovic, A.,& Dimitrijević, S.. (2021). Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society, 98(11).
https://doi.org/10.1016/j.jics.2021.100219
Dimitrijevic SB, Alagic S, Pavlovic S, Stankovic B, Kotur N, Ivanovic A, Dimitrijević S. Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society. 2021;98(11).
doi:10.1016/j.jics.2021.100219 .
Dimitrijevic, Silvana B., Alagic, Sladana, Pavlovic, Sonja, Stankovic, Biljana, Kotur, Nikola, Ivanovic, Aleksandra, Dimitrijević, Stevan, "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte" in Journal of the Indian Chemical Society, 98, no. 11 (2021),
https://doi.org/10.1016/j.jics.2021.100219 . .
