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dc.creatorPajić-Lijaković, Ivana
dc.creatorGuevorkian, Karine
dc.creatorBarriga, Elias H.
dc.creatorMunoz, Jose J.
dc.date.accessioned2022-03-04T11:18:40Z
dc.date.available2022-03-04T11:18:40Z
dc.date.issued2021
dc.identifier.issn2296-424X
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4829
dc.description.abstractThis issue gathers exciting multi-disciplinary work relating viscoelasticity and collective cell remodeling within various biological processes such as morphogenesis, tumorigenesis, and wound healing. Viscoelasticity is influenced by energy transfer and dissipation during cell rearrangement at various time and space scales. Cumulative structural changes at a subcellular level have effects on viscoelasticity at a supracellular level. Established configurations of migrating cells and the rate of their change, which significantly regulate viscoelasticity at a supracellular level, have the impact on the cohesiveness inhomogeneity and various mechanical and biochemical processes at a subcellular level. This Research Topic aims to connect the macroscopic viscoelastic parameters with the individual and collective cell response. Consideration of biochemical, biophysical and bio-mechanical aspects responsible for tissue remodeling, intercalation, and migration were discussed on various multicellular systems under in vivo and in vitro conditions. Thus in this Research Topic we aim to provide a state-of-the-art view about the current knowledge related to viscoelasticity caused by collective cell remodeling and adhesive contractile properties, covering a plethora of phenomena such as: 1) single cell response under stretched monolayers modeled with an improved Vertex model, 2) adhesion percolation within a tissue as an important factor which influences its viscoelasticity, 3) the active turbulence caused by collective cell migration accompanied with the generation of mechanical waves, 4) cell jamming state transitions, and 5) viscoelastic response characterization in liver diseases. Alternative techniques to measure and control cell rearrangement under various experimental conditions are also considered, including atomic force microscopy measurements and various elastography techniques. This Research Topic provides an overview of the current understanding of various: biological, biochemical, biophysical and mechanical aspects of cell remodeling. The inter-relation between cell remodeling and tissue viscoelasticity was discussed by emphasizing the relevant rheological parameters, the way of their measurement under in vivo/ in vitro conditions, and the strategy of multi-scale constitutive modeling.
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceFrontiers in Physics
dc.subjectviscoelasticity of multicellular systemsen
dc.subjectcollective cell rearrangementen
dc.subjectmulti scale mathematical modelingen
dc.subjectelastographyen
dc.subjectcell jamming state transitionen
dc.subjectactive elastic turbulenceen
dc.titleEditorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodelingen
dc.typecontributionToPeriodical
dc.rights.licenseBY
dc.citation.other9(): -
dc.citation.volume9
dc.identifier.doi10.3389/fphy.2021.773096
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/7966/Editorial_Viscoelasticity_From_pub_2021.pdf
dc.identifier.scopus2-s2.0-85117097383
dc.identifier.wos000717248300001
dc.type.versionpublishedVersion


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