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dc.creatorRudic, Suzana
dc.creatorDimitrijević-Branković, Suzana
dc.creatorDimitrijevic, Snezana
dc.creatorMilić, Marija
dc.date.accessioned2022-03-04T11:21:37Z
dc.date.available2022-03-04T11:21:37Z
dc.date.issued2021
dc.identifier.issn1383-5866
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4878
dc.description.abstractThis study has developed an improved and fast microwave-assisted procedure for extraction of high yields of natural antioxidants from artichoke leaves dust. The material is derived as an abundant residue remained after processing for the industrial tea blends preparation, having no commercial value. A key factors for optimization of the total polyphenolic (TPC) and flavonoid content (TFC) and antioxidant activities have been determined by using single factor experiments along with a response surface methodology. The optimal conditions for maximizing the combination of TPC/TFC and antioxidant activity were obtained as follows: ethanol concentration 67.81%, extraction time 50 s, liquid/solid ratio 41.78 mL/g, microwave power 180 W, whereas the corresponding responses resulted in: TPC - 205.59 +/- 7.30 mg GAE/g dw, TFC - 79.75 +/- 1.12 mg QE/g dw, and FRAP -1008.14 +/- 37.15 mmolFe2+/g dw. Only 14.7 mu g/mL of the extract concentration is required to inhibit 50% of DPPH free radicals. A comparative study confirmed that the proposed procedure yielded higher TPC, TFC and antioxidant activities than available extraction methods. It highlights a several fold reduced extraction time, caring an ecofriendly principle for obtaining of antioxidants from industrial, medicinal crop residues, which would be further easily valorized in food and pharmaceutical industry.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200135/RS//
dc.rightsrestrictedAccess
dc.sourceSeparation and Purification Technology
dc.subjectArtichoke leavesen
dc.subjectAntioxidantsen
dc.subjectPolyphenolsen
dc.subjectFlavonoidsen
dc.subjectMicrowave-assisted extractionen
dc.subjectResponse surface methodology (RSM)en
dc.titleValorization of unexploited artichoke leaves dust for obtaining of extracts rich in natural antioxidantsen
dc.typearticle
dc.rights.licenseARR
dc.citation.other256(): -
dc.citation.rankM21~
dc.citation.volume256
dc.identifier.doi10.1016/j.seppur.2020.117714
dc.identifier.rcubconv_6133
dc.identifier.scopus2-s2.0-85091971525
dc.identifier.wos000674613800002
dc.type.versionpublishedVersion


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