Приказ основних података о документу

dc.creatorTomić, Simonida
dc.creatorNikodinović-Runić, Jasmina
dc.creatorVukomanovic, Marija
dc.creatorBabić, Marija M.
dc.creatorVuković, Jovana
dc.date.accessioned2022-03-04T11:24:32Z
dc.date.available2022-03-04T11:24:32Z
dc.date.issued2021
dc.identifier.issn2073-4360
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4926
dc.description.abstractHydrogel scaffolding biomaterials are one of the most attractive polymeric biomaterials for regenerative engineering and can be engineered into tissue mimetic scaffolds to support cell growth due to their similarity to the native extracellular matrix. The novel, versatile hydrogel scaffolds based on alginate, gelatin, 2-hydroxyethyl methacrylate, and inorganic agent hydroxyapatite were prepared by modified cryogelation. The chemical composition, morphology, porosity, mechanical properties, effects on cell viability, in vitro degradation, in vitro and in vivo biocompatibility were tested to correlate the material's composition with the corresponding properties. Scaffolds showed an interconnected porous microstructure, satisfactory mechanical strength, favorable hydrophilicity, degradation, and suitable in vitro and in vivo biocompatible behavior. Materials showed good biocompatibility with healthy human fibroblast in cell culture, as well as in vivo with zebrafish assay, suggesting newly synthesized hydrogel scaffolds as a potential new generation of hydrogel scaffolding biomaterials with tunable properties for versatile biomedical applications and tissue regeneration.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172062/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourcePolymers
dc.subjectalginateen
dc.subjectgelatinen
dc.subject2-hydroxyethyl methacrylateen
dc.subjecthydroxyapatiteen
dc.subjecthydrogel scaffolding biomaterialen
dc.subjectdegradable scaffoldsen
dc.subjectbiocompatibilityen
dc.subjecttissue regeneration engineeringen
dc.titleNovel Hydrogel Scaffolds Based on Alginate, Gelatin, 2-Hydroxyethyl Methacrylate, and Hydroxyapatiteen
dc.typearticle
dc.rights.licenseBY
dc.citation.issue6
dc.citation.other13(6): -
dc.citation.rankM21
dc.citation.spage932
dc.citation.volume13
dc.identifier.doi10.3390/polym13060932
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/7868/Novel_hydrogel_scaffolds_pub_2021.pdf
dc.identifier.pmid33803545
dc.identifier.scopus2-s2.0-85103494235
dc.identifier.wos000651944700001
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу