Show simple item record

dc.creatorPajić-Lijaković, Ivana
dc.creatorMilivojević, Milan
dc.date.accessioned2022-03-04T11:26:46Z
dc.date.available2022-03-04T11:26:46Z
dc.date.issued2021
dc.identifier.issn0175-7571
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4965
dc.description.abstractCollective cell migration (CCM), a highly coordinated and fine-tuned migratory mode, is involved in a plethora of biological processes, such as embryogenesis, tissue repair and cancer invasion. Although a good comprehension of how cells collectively migrate by following molecular rules has been generated, the impact of cellular rearrangements on collective migration remains less understood. Thus, considering CCM from a multi-scale quantitative approach could result in a powerful tool to address the contribution of cellular rearrangements in CCM and help to understand this important but still controversial topic. In this work, a review of existing literature in CCM modeling at different scales is given along with assortment of published experimental findings, to invite experimentalists to test given theoretical considerations in multicellular systems. In addition, three different time and space scales (free or weakly connected cells, cluster of cells and collision fronts of different cells clusters) are considered and the multi-scale nature of those processes was discussed with special emphasis of jamming and unjamming states.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200135/RS//
dc.rightsrestrictedAccess
dc.sourceEuropean Biophysics Journal With Biophysics Letters
dc.subjectCollective cell migrationen
dc.subjectCell speeden
dc.subjectViscoelasticity of cellular domainsen
dc.subjectResidual stress accumulationen
dc.subjectJamming state transitionen
dc.titleMultiscale nature of cell rearrangement caused by collective cell migrationen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage14
dc.citation.issue1
dc.citation.other50(1): 1-14
dc.citation.rankM23~
dc.citation.spage1
dc.citation.volume50
dc.identifier.doi10.1007/s00249-021-01496-7
dc.identifier.pmid33495939
dc.identifier.rcubconv_6025
dc.identifier.scopus2-s2.0-85099928282
dc.identifier.wos000611453400001
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record