Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties
Authors
Lukić, Ivana
Pajnik, Jelena

Nišavić, Jakov
Tadić, Vanja

Vági, Erika
Szekely, Edit
Žižović, Irena

Article (Published version)
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The integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated mat...erials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1).
Keywords:
antiviral activity / Melissa officinalis / supercritical extraction / supercritical impregnationSource:
Processes, 2022, 10, 4, 680-Publisher:
- MDPI
Funding / projects:
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200135 (University of Belgrade, Faculty of Technology and Metallurgy) (RS-200135)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200287 (Innovation Center of the Faculty of Technology and Metallurgy) (RS-200287)
DOI: 10.3390/pr10040680
ISSN: 2227-9717
WoS: 00078613190000
Scopus: 2-s2.0-85128283805
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Tehnološko-metalurški fakultetTY - JOUR AU - Lukić, Ivana AU - Pajnik, Jelena AU - Nišavić, Jakov AU - Tadić, Vanja AU - Vági, Erika AU - Szekely, Edit AU - Žižović, Irena PY - 2022 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5113 AB - The integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated materials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1). PB - MDPI T2 - Processes T1 - Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties IS - 4 SP - 680 VL - 10 DO - 10.3390/pr10040680 ER -
@article{ author = "Lukić, Ivana and Pajnik, Jelena and Nišavić, Jakov and Tadić, Vanja and Vági, Erika and Szekely, Edit and Žižović, Irena", year = "2022", abstract = "The integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated materials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1).", publisher = "MDPI", journal = "Processes", title = "Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties", number = "4", pages = "680", volume = "10", doi = "10.3390/pr10040680" }
Lukić, I., Pajnik, J., Nišavić, J., Tadić, V., Vági, E., Szekely, E.,& Žižović, I.. (2022). Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties. in Processes MDPI., 10(4), 680. https://doi.org/10.3390/pr10040680
Lukić I, Pajnik J, Nišavić J, Tadić V, Vági E, Szekely E, Žižović I. Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties. in Processes. 2022;10(4):680. doi:10.3390/pr10040680 .
Lukić, Ivana, Pajnik, Jelena, Nišavić, Jakov, Tadić, Vanja, Vági, Erika, Szekely, Edit, Žižović, Irena, "Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties" in Processes, 10, no. 4 (2022):680, https://doi.org/10.3390/pr10040680 . .