The present study was focused on improving the supercritical fluid extraction process dedicated to the recovery of highly valuable extract from Silybum marianum seeds. At first, the process was tested using supercritical CO2 at temperatures of 40 and 80 °C and pressures ranging from 100 to 300 bar. Obtained values were described using two literature models with acceptable agreement of experimental and calculated data. Further, the effect of the equipment design and process scale-up was investigated in four high-pressure units having volumes in the range from 280 mL to 40 L resulting in extraction yields up to 26 %. Based on the values of the parameters determined at the laboratory scale, the extraction process was successfully transferred to a semi-industrial scale. Finally, estimated costs for supercritical extract production in Poland for the year 2021 using a 1000 L high-pressure unit amounted to the price of 35.9 EUR per kg of extract.
TY - JOUR
AU - Milovanović, Stoja
AU - Lukić, Ivana
AU - Stamenić, Marko
AU - Kamiński, Piotr
AU - Florkowski, Grzegorz
AU - Tyśkiewicz, Katarzyna
AU - Konkol, Marcin
PY - 2022
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5175
AB - The present study was focused on improving the supercritical fluid extraction process dedicated to the recovery of highly valuable extract from Silybum marianum seeds. At first, the process was tested using supercritical CO2 at temperatures of 40 and 80 °C and pressures ranging from 100 to 300 bar. Obtained values were described using two literature models with acceptable agreement of experimental and calculated data. Further, the effect of the equipment design and process scale-up was investigated in four high-pressure units having volumes in the range from 280 mL to 40 L resulting in extraction yields up to 26 %. Based on the values of the parameters determined at the laboratory scale, the extraction process was successfully transferred to a semi-industrial scale. Finally, estimated costs for supercritical extract production in Poland for the year 2021 using a 1000 L high-pressure unit amounted to the price of 35.9 EUR per kg of extract.
PB - Elsevier B.V.
T2 - Journal of Supercritical Fluids
T1 - The effect of equipment design and process scale-up on supercritical CO2 extraction: Case study for Silybum marianum seeds
SP - 105676
VL - 188
DO - 10.1016/j.supflu.2022.105676
ER -
@article{
author = "Milovanović, Stoja and Lukić, Ivana and Stamenić, Marko and Kamiński, Piotr and Florkowski, Grzegorz and Tyśkiewicz, Katarzyna and Konkol, Marcin",
year = "2022",
abstract = "The present study was focused on improving the supercritical fluid extraction process dedicated to the recovery of highly valuable extract from Silybum marianum seeds. At first, the process was tested using supercritical CO2 at temperatures of 40 and 80 °C and pressures ranging from 100 to 300 bar. Obtained values were described using two literature models with acceptable agreement of experimental and calculated data. Further, the effect of the equipment design and process scale-up was investigated in four high-pressure units having volumes in the range from 280 mL to 40 L resulting in extraction yields up to 26 %. Based on the values of the parameters determined at the laboratory scale, the extraction process was successfully transferred to a semi-industrial scale. Finally, estimated costs for supercritical extract production in Poland for the year 2021 using a 1000 L high-pressure unit amounted to the price of 35.9 EUR per kg of extract.",
publisher = "Elsevier B.V.",
journal = "Journal of Supercritical Fluids",
title = "The effect of equipment design and process scale-up on supercritical CO2 extraction: Case study for Silybum marianum seeds",
pages = "105676",
volume = "188",
doi = "10.1016/j.supflu.2022.105676"
}
Milovanović, S., Lukić, I., Stamenić, M., Kamiński, P., Florkowski, G., Tyśkiewicz, K.,& Konkol, M.. (2022). The effect of equipment design and process scale-up on supercritical CO2 extraction: Case study for Silybum marianum seeds. in Journal of Supercritical Fluids
Elsevier B.V.., 188, 105676.
https://doi.org/10.1016/j.supflu.2022.105676
Milovanović S, Lukić I, Stamenić M, Kamiński P, Florkowski G, Tyśkiewicz K, Konkol M. The effect of equipment design and process scale-up on supercritical CO2 extraction: Case study for Silybum marianum seeds. in Journal of Supercritical Fluids. 2022;188:105676.
doi:10.1016/j.supflu.2022.105676 .
Milovanović, Stoja, Lukić, Ivana, Stamenić, Marko, Kamiński, Piotr, Florkowski, Grzegorz, Tyśkiewicz, Katarzyna, Konkol, Marcin, "The effect of equipment design and process scale-up on supercritical CO2 extraction: Case study for Silybum marianum seeds" in Journal of Supercritical Fluids, 188 (2022):105676,
https://doi.org/10.1016/j.supflu.2022.105676 . .
