Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity
Само за регистроване кориснике
2003
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The chromatographic behavior of Para-substituted amides of alpha-phenylacetic, benzoic, propanoic, and 2,2-dimethylpropanoic acid has been studied in reversed-phase thin-layer chromatography on silica gel impregnated with paraffin oil. Mobile phases used were acetone-water, methanol-water, and dioxane-water. R-M(0) values were calculated by linear extrapolation of retention to 0% organic modifier for each mobile phase. The relationships between R-M(0) Values obtained with different organic modifiers in the mobile phases are discussed. C-0 values were obtained from the slopes and intercepts of linear relationships between retention and volume fraction of modifier. Correlation between partition coefficient, log P, and R-M(0) and between log P and C-0 was examined. Results show that C-0 is a better measure of the lipophilicity of the amides than R-M(0).
Кључне речи:
amides / R-M(0) / log P / C-0 / impregnated silica gelИзвор:
JPC-Journal of Planar Chromatography-Modern Tlc, 2003, 16, 2, 147-153Издавач:
- Springer Heidelberg, Heidelberg
DOI: 10.1556/JPC.16.2003.2.12
ISSN: 0933-4173
WoS: 000183519300012
Scopus: 2-s2.0-18344402163
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Đaković-Sekulić, Tatjana AU - Perišić-Janjić, Nada AU - Petrović, Slobodan PY - 2003 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/524 AB - The chromatographic behavior of Para-substituted amides of alpha-phenylacetic, benzoic, propanoic, and 2,2-dimethylpropanoic acid has been studied in reversed-phase thin-layer chromatography on silica gel impregnated with paraffin oil. Mobile phases used were acetone-water, methanol-water, and dioxane-water. R-M(0) values were calculated by linear extrapolation of retention to 0% organic modifier for each mobile phase. The relationships between R-M(0) Values obtained with different organic modifiers in the mobile phases are discussed. C-0 values were obtained from the slopes and intercepts of linear relationships between retention and volume fraction of modifier. Correlation between partition coefficient, log P, and R-M(0) and between log P and C-0 was examined. Results show that C-0 is a better measure of the lipophilicity of the amides than R-M(0). PB - Springer Heidelberg, Heidelberg T2 - JPC-Journal of Planar Chromatography-Modern Tlc T1 - Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity EP - 153 IS - 2 SP - 147 VL - 16 DO - 10.1556/JPC.16.2003.2.12 ER -
@article{ author = "Đaković-Sekulić, Tatjana and Perišić-Janjić, Nada and Petrović, Slobodan", year = "2003", abstract = "The chromatographic behavior of Para-substituted amides of alpha-phenylacetic, benzoic, propanoic, and 2,2-dimethylpropanoic acid has been studied in reversed-phase thin-layer chromatography on silica gel impregnated with paraffin oil. Mobile phases used were acetone-water, methanol-water, and dioxane-water. R-M(0) values were calculated by linear extrapolation of retention to 0% organic modifier for each mobile phase. The relationships between R-M(0) Values obtained with different organic modifiers in the mobile phases are discussed. C-0 values were obtained from the slopes and intercepts of linear relationships between retention and volume fraction of modifier. Correlation between partition coefficient, log P, and R-M(0) and between log P and C-0 was examined. Results show that C-0 is a better measure of the lipophilicity of the amides than R-M(0).", publisher = "Springer Heidelberg, Heidelberg", journal = "JPC-Journal of Planar Chromatography-Modern Tlc", title = "Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity", pages = "153-147", number = "2", volume = "16", doi = "10.1556/JPC.16.2003.2.12" }
Đaković-Sekulić, T., Perišić-Janjić, N.,& Petrović, S.. (2003). Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity. in JPC-Journal of Planar Chromatography-Modern Tlc Springer Heidelberg, Heidelberg., 16(2), 147-153. https://doi.org/10.1556/JPC.16.2003.2.12
Đaković-Sekulić T, Perišić-Janjić N, Petrović S. Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity. in JPC-Journal of Planar Chromatography-Modern Tlc. 2003;16(2):147-153. doi:10.1556/JPC.16.2003.2.12 .
Đaković-Sekulić, Tatjana, Perišić-Janjić, Nada, Petrović, Slobodan, "Influence of the mobile-phase modifier on the retention of some para-substituted amides; Correlation with compound lipophilicity" in JPC-Journal of Planar Chromatography-Modern Tlc, 16, no. 2 (2003):147-153, https://doi.org/10.1556/JPC.16.2003.2.12 . .