The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Primary stability of biomaterials is associated with the mechanical contact of an implant
with the surrounding bone, which is governed by surface properties. The implant often needs
some kind of modification to optimize and improve biological properties of the surface. In the
present study, nanotubular oxide layer on Ti-13Nb-13Zr alloy (coarse-grained, CG, and ultrafine-grained, UFG, obtained by high pressure torsion) alloy was formed by means of electrochemical anodization in the 1M H3PO4 + NaF electrolyte, during 60 and 90 minutes. The atomic force
microscopy (AFM) was studied to characterize the surface topography and it was shown that
highly ordered nanotubular layers were obtained by anodization. Also, results show that increasing anodizing time increases roughness of the surface. The aim of this paper is to determine the
vitro biocompatibility of the titanium alloy after electrochemical anodization. In vitro nanotubular oxide layer examinations were performed on the human f...ibroblast cell lines (MRC-5). The cytotoxicity of the examined materials was measured as a percent of cell growth inhibition using in
vitro colorimetric methyl-thiazol-tetrazolium (MTT) test. Scanning Electron Microscope (SEM)
observation of MRC-5 cell was performed using a SEM MIRA3 TESCAN which operated at an
accelerating voltage of 4.5 keV. Results show that nanotubular oxide layer formed on the UFG
Ti-13Nb-13Zr alloy during 90 minutes indicates better cells contact and spreading along nanotubular surface.
Извор:
Serbian Ceramic Society, 2018, 85-Издавач:
- Serbian Academy of Sciences and Arts, Serbia, Belgrade
Финансирање / пројекти:
- Микромеханички критеријуми оштећења и лома (RS-MESTD-Basic Research (BR or ON)-174004)
Институција/група
Tehnološko-metalurški fakultetTY - CONF AU - Barjaktarević, Dragana AU - Veljović, Đorđe AU - Dimić, Ivana AU - Đokić, Veljko AU - Rakin, Marko PY - 2018 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5255 AB - Primary stability of biomaterials is associated with the mechanical contact of an implant with the surrounding bone, which is governed by surface properties. The implant often needs some kind of modification to optimize and improve biological properties of the surface. In the present study, nanotubular oxide layer on Ti-13Nb-13Zr alloy (coarse-grained, CG, and ultrafine-grained, UFG, obtained by high pressure torsion) alloy was formed by means of electrochemical anodization in the 1M H3PO4 + NaF electrolyte, during 60 and 90 minutes. The atomic force microscopy (AFM) was studied to characterize the surface topography and it was shown that highly ordered nanotubular layers were obtained by anodization. Also, results show that increasing anodizing time increases roughness of the surface. The aim of this paper is to determine the vitro biocompatibility of the titanium alloy after electrochemical anodization. In vitro nanotubular oxide layer examinations were performed on the human fibroblast cell lines (MRC-5). The cytotoxicity of the examined materials was measured as a percent of cell growth inhibition using in vitro colorimetric methyl-thiazol-tetrazolium (MTT) test. Scanning Electron Microscope (SEM) observation of MRC-5 cell was performed using a SEM MIRA3 TESCAN which operated at an accelerating voltage of 4.5 keV. Results show that nanotubular oxide layer formed on the UFG Ti-13Nb-13Zr alloy during 90 minutes indicates better cells contact and spreading along nanotubular surface. PB - Serbian Academy of Sciences and Arts, Serbia, Belgrade C3 - Serbian Ceramic Society T1 - The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy SP - 85 UR - https://hdl.handle.net/21.15107/rcub_technorep_5255 ER -
@conference{ author = "Barjaktarević, Dragana and Veljović, Đorđe and Dimić, Ivana and Đokić, Veljko and Rakin, Marko", year = "2018", abstract = "Primary stability of biomaterials is associated with the mechanical contact of an implant with the surrounding bone, which is governed by surface properties. The implant often needs some kind of modification to optimize and improve biological properties of the surface. In the present study, nanotubular oxide layer on Ti-13Nb-13Zr alloy (coarse-grained, CG, and ultrafine-grained, UFG, obtained by high pressure torsion) alloy was formed by means of electrochemical anodization in the 1M H3PO4 + NaF electrolyte, during 60 and 90 minutes. The atomic force microscopy (AFM) was studied to characterize the surface topography and it was shown that highly ordered nanotubular layers were obtained by anodization. Also, results show that increasing anodizing time increases roughness of the surface. The aim of this paper is to determine the vitro biocompatibility of the titanium alloy after electrochemical anodization. In vitro nanotubular oxide layer examinations were performed on the human fibroblast cell lines (MRC-5). The cytotoxicity of the examined materials was measured as a percent of cell growth inhibition using in vitro colorimetric methyl-thiazol-tetrazolium (MTT) test. Scanning Electron Microscope (SEM) observation of MRC-5 cell was performed using a SEM MIRA3 TESCAN which operated at an accelerating voltage of 4.5 keV. Results show that nanotubular oxide layer formed on the UFG Ti-13Nb-13Zr alloy during 90 minutes indicates better cells contact and spreading along nanotubular surface.", publisher = "Serbian Academy of Sciences and Arts, Serbia, Belgrade", journal = "Serbian Ceramic Society", title = "The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy", pages = "85", url = "https://hdl.handle.net/21.15107/rcub_technorep_5255" }
Barjaktarević, D., Veljović, Đ., Dimić, I., Đokić, V.,& Rakin, M.. (2018). The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy. in Serbian Ceramic Society Serbian Academy of Sciences and Arts, Serbia, Belgrade., 85. https://hdl.handle.net/21.15107/rcub_technorep_5255
Barjaktarević D, Veljović Đ, Dimić I, Đokić V, Rakin M. The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy. in Serbian Ceramic Society. 2018;:85. https://hdl.handle.net/21.15107/rcub_technorep_5255 .
Barjaktarević, Dragana, Veljović, Đorđe, Dimić, Ivana, Đokić, Veljko, Rakin, Marko, "The biocompatibility of nanotubular oxide layer formed on the ultrafine-grained Ti-13Nb-13Zr alloy" in Serbian Ceramic Society (2018):85, https://hdl.handle.net/21.15107/rcub_technorep_5255 .