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Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester

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2009
Authors
Kaluđerović, Goran N.
Vasiljevic, Tanja M.
Lausevic, Mila D.
Gaballa, Akmal S.
Sabo, Tibor
Article (Published version)
Metadata
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Abstract
The electrospray mass spectrometric (ESI-MS) behavior of the complexes trans-dichloro(ethylenediamine-N, N'-di-3-propionato) platinum(IV), trans-dibromo(ethylenediamine-N, N'-di-3-propionato) platinum( IV), dichloro (ethylenediamine-N,N'-di-3-propionic acid) platinum(II), tetrachloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum(IV), chlorotribromo(O,O'-di-n-butylethylenediamine-N,N'-di-3-propanoate) platinum(IV), and dichloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum( II), with the formulae trans-[PtCl(2) (eddp)] (1), trans-[PtBr(2)(eddp)] (2), [PtCl(2)(H(2)eddp)] (3), [PtCl(4)(Bu(2)eddp)] (4), [PtBr(3)Cl(Bu(2)eddp)] (5), and [PtCl(2)(Bu(2)eddp)]center dot H(2)O (6), is reported. The deprotonated molecular ions or halide adducts are usually observed. ESI-MS data demonstrate the usefulness of the method for efficient characterization of metal complexes in solution.
Keywords:
Platinum(II) complexes / Platinum(IV) complexes / Edda / Eddp / ESI-MS
Source:
Monatshefte Fur Chemie, 2009, 140, 5, 553-557
Publisher:
  • Springer Wien, Wien
Funding / projects:
  • Synthesis, characterization and activity of organic and coordination composition and their application in (bio) nanotechnology (RS-142010)
  • Razvoj metoda za separaciju, predkoncentrisanje, određivanje i uklanjanje zagađivača okoline (RS-142002)

DOI: 10.1007/s00706-008-0088-0

ISSN: 0026-9247

WoS: 000264874000013

Scopus: 2-s2.0-64149114609
[ Google Scholar ]
6
6
URI
http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5526
Collections
  • Radovi istraživača / Researchers’ publications (TMF)
Institution/Community
Tehnološko-metalurški fakultet
TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Vasiljevic, Tanja M.
AU  - Lausevic, Mila D.
AU  - Gaballa, Akmal S.
AU  - Sabo, Tibor
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5526
AB  - The electrospray mass spectrometric (ESI-MS) behavior of the complexes trans-dichloro(ethylenediamine-N, N'-di-3-propionato) platinum(IV), trans-dibromo(ethylenediamine-N, N'-di-3-propionato) platinum( IV), dichloro (ethylenediamine-N,N'-di-3-propionic acid) platinum(II), tetrachloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum(IV), chlorotribromo(O,O'-di-n-butylethylenediamine-N,N'-di-3-propanoate) platinum(IV), and dichloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum( II), with the formulae trans-[PtCl(2) (eddp)] (1), trans-[PtBr(2)(eddp)] (2), [PtCl(2)(H(2)eddp)] (3), [PtCl(4)(Bu(2)eddp)] (4), [PtBr(3)Cl(Bu(2)eddp)] (5), and [PtCl(2)(Bu(2)eddp)]center dot H(2)O (6), is reported. The deprotonated molecular ions or halide adducts are usually observed. ESI-MS data demonstrate the usefulness of the method for efficient characterization of metal complexes in solution.
PB  - Springer Wien, Wien
T2  - Monatshefte Fur Chemie
T1  - Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester
EP  - 557
IS  - 5
SP  - 553
VL  - 140
DO  - 10.1007/s00706-008-0088-0
ER  - 
@article{
author = "Kaluđerović, Goran N. and Vasiljevic, Tanja M. and Lausevic, Mila D. and Gaballa, Akmal S. and Sabo, Tibor",
year = "2009",
abstract = "The electrospray mass spectrometric (ESI-MS) behavior of the complexes trans-dichloro(ethylenediamine-N, N'-di-3-propionato) platinum(IV), trans-dibromo(ethylenediamine-N, N'-di-3-propionato) platinum( IV), dichloro (ethylenediamine-N,N'-di-3-propionic acid) platinum(II), tetrachloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum(IV), chlorotribromo(O,O'-di-n-butylethylenediamine-N,N'-di-3-propanoate) platinum(IV), and dichloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum( II), with the formulae trans-[PtCl(2) (eddp)] (1), trans-[PtBr(2)(eddp)] (2), [PtCl(2)(H(2)eddp)] (3), [PtCl(4)(Bu(2)eddp)] (4), [PtBr(3)Cl(Bu(2)eddp)] (5), and [PtCl(2)(Bu(2)eddp)]center dot H(2)O (6), is reported. The deprotonated molecular ions or halide adducts are usually observed. ESI-MS data demonstrate the usefulness of the method for efficient characterization of metal complexes in solution.",
publisher = "Springer Wien, Wien",
journal = "Monatshefte Fur Chemie",
title = "Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester",
pages = "557-553",
number = "5",
volume = "140",
doi = "10.1007/s00706-008-0088-0"
}
Kaluđerović, G. N., Vasiljevic, T. M., Lausevic, M. D., Gaballa, A. S.,& Sabo, T.. (2009). Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester. in Monatshefte Fur Chemie
Springer Wien, Wien., 140(5), 553-557.
https://doi.org/10.1007/s00706-008-0088-0
Kaluđerović GN, Vasiljevic TM, Lausevic MD, Gaballa AS, Sabo T. Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester. in Monatshefte Fur Chemie. 2009;140(5):553-557.
doi:10.1007/s00706-008-0088-0 .
Kaluđerović, Goran N., Vasiljevic, Tanja M., Lausevic, Mila D., Gaballa, Akmal S., Sabo, Tibor, "Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester" in Monatshefte Fur Chemie, 140, no. 5 (2009):553-557,
https://doi.org/10.1007/s00706-008-0088-0 . .

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