Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry
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2010
Authors
Trtić-Petrović, Tatjana M.
Đorđević, Jelena S.

Dujaković, Nikolina
Kumrić, Ksenija
Vasiljević, Tatjana

Laušević, Mila
Article (Published version)

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An optimised extraction and cleanup method for the analysis of pesticide in natural water samples is presented. Sixteen pesticides of different polarity and from the different chemical classes (organophosphates, triazines, benzimidazoles, carbamates, carbamides, neonicotinoides, methylureas, phenylureas and benzohydrazides), most frequently used in Serbia, were selected for the analysis. Liquid-phase microextraction in a single hollow fibre (HF-LPME) has been applied for sample preparation. The concentrations of pesticides were determined using HPLC-MS/MS method with electrospray ionisation. The extraction behaviour and selection of the experimental conditions was predicted based on log D and pK (a) values of targeted pesticides, which were calculated applying the computer software ACD/Labs PhysChem Suite v12. The influence of the donor pH and concentration of pesticides, organic phase composition as well as the extraction time on the extraction efficiency was investigated. Optimum ext...raction conditions were evaluated with respect to the investigated parameters of the extraction. The extraction method was validated for 10 out of 16 studied pesticides. Linear range of the pesticides was 0.1-5 A mu g L(-1) with the correlation coefficient from 0.991 to 0.9998, and the relative standard deviation for three standard measurements was between 0.2 and 11.8%. The limits of detections ranged from 0.026 to 0.237 A mu g L(-1) and the limits of quantifications from 0.094 to 0.793 A mu g L(-1). The optimised two-phase HF-LPME method was successfully applied for determination of moderately polar as well low-polar pesticides in the environmental water samples.
Keywords:
HPLC-MS/MS / Liquid-phase microextraction / Pesticides / Sample preparationSource:
Analytical and Bioanalytical Chemistry, 2010, 397, 6, 2233-2243Funding / projects:
- Razvoj metoda za separaciju, predkoncentrisanje, određivanje i uklanjanje zagađivača okoline (RS-142002)
- Fizika i hemija sa jonskim snopovima (RS-151005)
Note:
- 6th International Conference on Instrumental Methods of Analysis, Oct 04-08, 2009, Athens, Greece
DOI: 10.1007/s00216-010-3725-5
ISSN: 1618-2642
PubMed: 20442990
WoS: 000279453000024
Scopus: 2-s2.0-77956247282
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Trtić-Petrović, Tatjana M. AU - Đorđević, Jelena S. AU - Dujaković, Nikolina AU - Kumrić, Ksenija AU - Vasiljević, Tatjana AU - Laušević, Mila PY - 2010 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5590 AB - An optimised extraction and cleanup method for the analysis of pesticide in natural water samples is presented. Sixteen pesticides of different polarity and from the different chemical classes (organophosphates, triazines, benzimidazoles, carbamates, carbamides, neonicotinoides, methylureas, phenylureas and benzohydrazides), most frequently used in Serbia, were selected for the analysis. Liquid-phase microextraction in a single hollow fibre (HF-LPME) has been applied for sample preparation. The concentrations of pesticides were determined using HPLC-MS/MS method with electrospray ionisation. The extraction behaviour and selection of the experimental conditions was predicted based on log D and pK (a) values of targeted pesticides, which were calculated applying the computer software ACD/Labs PhysChem Suite v12. The influence of the donor pH and concentration of pesticides, organic phase composition as well as the extraction time on the extraction efficiency was investigated. Optimum extraction conditions were evaluated with respect to the investigated parameters of the extraction. The extraction method was validated for 10 out of 16 studied pesticides. Linear range of the pesticides was 0.1-5 A mu g L(-1) with the correlation coefficient from 0.991 to 0.9998, and the relative standard deviation for three standard measurements was between 0.2 and 11.8%. The limits of detections ranged from 0.026 to 0.237 A mu g L(-1) and the limits of quantifications from 0.094 to 0.793 A mu g L(-1). The optimised two-phase HF-LPME method was successfully applied for determination of moderately polar as well low-polar pesticides in the environmental water samples. T2 - Analytical and Bioanalytical Chemistry T1 - Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry EP - 2243 IS - 6 SP - 2233 VL - 397 DO - 10.1007/s00216-010-3725-5 ER -
@article{ author = "Trtić-Petrović, Tatjana M. and Đorđević, Jelena S. and Dujaković, Nikolina and Kumrić, Ksenija and Vasiljević, Tatjana and Laušević, Mila", year = "2010", abstract = "An optimised extraction and cleanup method for the analysis of pesticide in natural water samples is presented. Sixteen pesticides of different polarity and from the different chemical classes (organophosphates, triazines, benzimidazoles, carbamates, carbamides, neonicotinoides, methylureas, phenylureas and benzohydrazides), most frequently used in Serbia, were selected for the analysis. Liquid-phase microextraction in a single hollow fibre (HF-LPME) has been applied for sample preparation. The concentrations of pesticides were determined using HPLC-MS/MS method with electrospray ionisation. The extraction behaviour and selection of the experimental conditions was predicted based on log D and pK (a) values of targeted pesticides, which were calculated applying the computer software ACD/Labs PhysChem Suite v12. The influence of the donor pH and concentration of pesticides, organic phase composition as well as the extraction time on the extraction efficiency was investigated. Optimum extraction conditions were evaluated with respect to the investigated parameters of the extraction. The extraction method was validated for 10 out of 16 studied pesticides. Linear range of the pesticides was 0.1-5 A mu g L(-1) with the correlation coefficient from 0.991 to 0.9998, and the relative standard deviation for three standard measurements was between 0.2 and 11.8%. The limits of detections ranged from 0.026 to 0.237 A mu g L(-1) and the limits of quantifications from 0.094 to 0.793 A mu g L(-1). The optimised two-phase HF-LPME method was successfully applied for determination of moderately polar as well low-polar pesticides in the environmental water samples.", journal = "Analytical and Bioanalytical Chemistry", title = "Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry", pages = "2243-2233", number = "6", volume = "397", doi = "10.1007/s00216-010-3725-5" }
Trtić-Petrović, T. M., Đorđević, J. S., Dujaković, N., Kumrić, K., Vasiljević, T.,& Laušević, M.. (2010). Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry. in Analytical and Bioanalytical Chemistry, 397(6), 2233-2243. https://doi.org/10.1007/s00216-010-3725-5
Trtić-Petrović TM, Đorđević JS, Dujaković N, Kumrić K, Vasiljević T, Laušević M. Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry. in Analytical and Bioanalytical Chemistry. 2010;397(6):2233-2243. doi:10.1007/s00216-010-3725-5 .
Trtić-Petrović, Tatjana M., Đorđević, Jelena S., Dujaković, Nikolina, Kumrić, Ksenija, Vasiljević, Tatjana, Laušević, Mila, "Determination of selected pesticides in environmental water by employing liquid-phase microextraction and liquid chromatography-tandem mass spectrometry" in Analytical and Bioanalytical Chemistry, 397, no. 6 (2010):2233-2243, https://doi.org/10.1007/s00216-010-3725-5 . .