The chromatographic behavior of four group of s-triazine derivatives (14 compounds) has been studied by TLC on silica gel impregnated with paraffin oil. Retention mechanism has been determined using the following mobile phases: water-acetone, water-acetonitrile, water-dioxane, water-tetrahydrofuran, water-methanol and water-ethanol, by changing the volume fraction of modifier in the mobile phase. On impregnated silica gel, a reversed-phase chromatographic process occurs. Good correlation was obtained between the retention constants, RMθ (determined by linear extrapolation), and slope, S, of chromatographic equations. There was also satisfactory correlation between these retention constants and logP values calculated using different theoretical methods. The study showed that the retention constants can be used as a measure of lipophilicity of investigated compounds.
Keywords:
Impregnated silica gel / Lipophilicity / Multiple linear regression analysis / RP-TLC / S-Triazine derivatives
TY - JOUR
AU - Jevrić, Lidija R.
AU - Koprivica, Gordana B.
AU - Mišljenović, Nevena M.
AU - Jovanović, Bratislav Ž.
PY - 2010
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5599
AB - The chromatographic behavior of four group of s-triazine derivatives (14 compounds) has been studied by TLC on silica gel impregnated with paraffin oil. Retention mechanism has been determined using the following mobile phases: water-acetone, water-acetonitrile, water-dioxane, water-tetrahydrofuran, water-methanol and water-ethanol, by changing the volume fraction of modifier in the mobile phase. On impregnated silica gel, a reversed-phase chromatographic process occurs. Good correlation was obtained between the retention constants, RMθ (determined by linear extrapolation), and slope, S, of chromatographic equations. There was also satisfactory correlation between these retention constants and logP values calculated using different theoretical methods. The study showed that the retention constants can be used as a measure of lipophilicity of investigated compounds.
PB - Univerzitet u Novom Sadu
T2 - Acta Periodica Technologica
T1 - Chromatographic behavior and lipophilicity of s-triazine derivatives on silica gel impregnated with paraffin oil
EP - 168
SP - 159
VL - 41
DO - 10.2298/APT1041159J
ER -
@article{
author = "Jevrić, Lidija R. and Koprivica, Gordana B. and Mišljenović, Nevena M. and Jovanović, Bratislav Ž.",
year = "2010",
abstract = "The chromatographic behavior of four group of s-triazine derivatives (14 compounds) has been studied by TLC on silica gel impregnated with paraffin oil. Retention mechanism has been determined using the following mobile phases: water-acetone, water-acetonitrile, water-dioxane, water-tetrahydrofuran, water-methanol and water-ethanol, by changing the volume fraction of modifier in the mobile phase. On impregnated silica gel, a reversed-phase chromatographic process occurs. Good correlation was obtained between the retention constants, RMθ (determined by linear extrapolation), and slope, S, of chromatographic equations. There was also satisfactory correlation between these retention constants and logP values calculated using different theoretical methods. The study showed that the retention constants can be used as a measure of lipophilicity of investigated compounds.",
publisher = "Univerzitet u Novom Sadu",
journal = "Acta Periodica Technologica",
title = "Chromatographic behavior and lipophilicity of s-triazine derivatives on silica gel impregnated with paraffin oil",
pages = "168-159",
volume = "41",
doi = "10.2298/APT1041159J"
}
Jevrić, L. R., Koprivica, G. B., Mišljenović, N. M.,& Jovanović, B. Ž.. (2010). Chromatographic behavior and lipophilicity of s-triazine derivatives on silica gel impregnated with paraffin oil. in Acta Periodica Technologica
Univerzitet u Novom Sadu., 41, 159-168.
https://doi.org/10.2298/APT1041159J
Jevrić LR, Koprivica GB, Mišljenović NM, Jovanović BŽ. Chromatographic behavior and lipophilicity of s-triazine derivatives on silica gel impregnated with paraffin oil. in Acta Periodica Technologica. 2010;41:159-168.
doi:10.2298/APT1041159J .
Jevrić, Lidija R., Koprivica, Gordana B., Mišljenović, Nevena M., Jovanović, Bratislav Ž., "Chromatographic behavior and lipophilicity of s-triazine derivatives on silica gel impregnated with paraffin oil" in Acta Periodica Technologica, 41 (2010):159-168,
https://doi.org/10.2298/APT1041159J . .
