The analytical properties of an analytical method must be evaluated through validation protocols. Beside specificity and/or selectivity, linearity of calibration, repeatability and accuracy, the most important parameters are: LOD (limit of detection) and LOQ (limit of quantification). Through these limits, it is possible to define the smallest concentration of analyte that can be reliably detected and quantified. To establish these limits, an analyst should apply several estimation methods and test a large number of sample replicates. It is difficult to make a compromise between complex statistical programs and the simple analytical demand to have reliable analytical parameters. The differences and equivalency of estimation methods and approaches for analytical limits could be overcome by an experimental comparison. In this paper, the focus is the LOD of inductively coupled plasma-mass spectrometry (ICP-MS) measurements employed for the determination of arsenic. The current approaches ...for the calculation of the LOD are summarized and critically discussed. (C) 2012 Elsevier B.V. All rights reserved.
Ključne reči:
Limit of detection / Estimation approaches / Arsenic / ICP-MS
TY - JOUR
AU - Rajaković, Ljubinka V.
AU - Markovic, Dana D.
AU - Rajaković-Ognjanović, Vladana N.
AU - Antanasijević, Davor Z.
PY - 2012
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5737
AB - The analytical properties of an analytical method must be evaluated through validation protocols. Beside specificity and/or selectivity, linearity of calibration, repeatability and accuracy, the most important parameters are: LOD (limit of detection) and LOQ (limit of quantification). Through these limits, it is possible to define the smallest concentration of analyte that can be reliably detected and quantified. To establish these limits, an analyst should apply several estimation methods and test a large number of sample replicates. It is difficult to make a compromise between complex statistical programs and the simple analytical demand to have reliable analytical parameters. The differences and equivalency of estimation methods and approaches for analytical limits could be overcome by an experimental comparison. In this paper, the focus is the LOD of inductively coupled plasma-mass spectrometry (ICP-MS) measurements employed for the determination of arsenic. The current approaches for the calculation of the LOD are summarized and critically discussed. (C) 2012 Elsevier B.V. All rights reserved.
T2 - Talanta
T1 - Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic
EP - 87
IS - SI
SP - 79
VL - 102
DO - 10.1016/j.talanta.2012.08.016
ER -
@article{
author = "Rajaković, Ljubinka V. and Markovic, Dana D. and Rajaković-Ognjanović, Vladana N. and Antanasijević, Davor Z.",
year = "2012",
abstract = "The analytical properties of an analytical method must be evaluated through validation protocols. Beside specificity and/or selectivity, linearity of calibration, repeatability and accuracy, the most important parameters are: LOD (limit of detection) and LOQ (limit of quantification). Through these limits, it is possible to define the smallest concentration of analyte that can be reliably detected and quantified. To establish these limits, an analyst should apply several estimation methods and test a large number of sample replicates. It is difficult to make a compromise between complex statistical programs and the simple analytical demand to have reliable analytical parameters. The differences and equivalency of estimation methods and approaches for analytical limits could be overcome by an experimental comparison. In this paper, the focus is the LOD of inductively coupled plasma-mass spectrometry (ICP-MS) measurements employed for the determination of arsenic. The current approaches for the calculation of the LOD are summarized and critically discussed. (C) 2012 Elsevier B.V. All rights reserved.",
journal = "Talanta",
title = "Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic",
pages = "87-79",
number = "SI",
volume = "102",
doi = "10.1016/j.talanta.2012.08.016"
}
Rajaković, L. V., Markovic, D. D., Rajaković-Ognjanović, V. N.,& Antanasijević, D. Z.. (2012). Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic. in Talanta, 102(SI), 79-87.
https://doi.org/10.1016/j.talanta.2012.08.016
Rajaković LV, Markovic DD, Rajaković-Ognjanović VN, Antanasijević DZ. Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic. in Talanta. 2012;102(SI):79-87.
doi:10.1016/j.talanta.2012.08.016 .
Rajaković, Ljubinka V., Markovic, Dana D., Rajaković-Ognjanović, Vladana N., Antanasijević, Davor Z., "Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic" in Talanta, 102, no. SI (2012):79-87,
https://doi.org/10.1016/j.talanta.2012.08.016 . .
