Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis
Abstract
For the first time, particle shape analysis of silica coated iron oxide (maghemite/magnetite) nanoparticle clusters (core-shell nanostructures) is discussed using computational methods. We analyzed three samples of core-shell nanostructures synthesized with different thickness of the silica shell. A new computational method is presented and successfully applied to the segmentation of the core-shell nanoparticles, as one of the main problems in image analysis of the TEM micrographs. We have introduced the circularity coefficient, marked with k(circ) and defined as the ratio of circularity measure C-2(S) of nanoparticles core and circularity measure core-shell nanoparticles in order to answer the question how the shell affects the overall shape of the final core-shell structure, with respect to circularity. More precisely, the circularity coefficient determines whether the circularity of the core-shell nanoparticle is higher, lower or equal to the circularity of the core. We have also de...termined the shells share in the overall area of the core-shell nanoparticle. The core-shell nanoparticle clusters here investigated exhibit superparamagnetic properties at room temperature, thus emphasizing their potential for use in practical applications such as in biomedical and particle separation. We show that the saturation magnetization strength can be easily adjusted by controlling the thickness of the silica shell. (C) 2016 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
Keywords:
Synthesis / Superparamagnetism / Magnetic properties / Image analysis / Circularity / Shape descriptorsSource:
Ceramics International, 2016, 42, 9, 10976-10984Publisher:
- Elsevier
Funding / projects:
- Magnetic and radionuclide labeled nanostructured materials for medical applications (RS-45015)
- Representations of logical structures and formal languages and their application in computing (RS-174026)
DOI: 10.1016/j.ceramint.2016.03.235
ISSN: 0272-8842; 1873-3956
WoS: 000376693800060
Scopus: 2-s2.0-84961908018
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Kopanja, Lazar AU - Kralj, Slavko AU - Žunić, Dragiša AU - Lončar, Boris B. AU - Tadić, Marin PY - 2016 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5810 AB - For the first time, particle shape analysis of silica coated iron oxide (maghemite/magnetite) nanoparticle clusters (core-shell nanostructures) is discussed using computational methods. We analyzed three samples of core-shell nanostructures synthesized with different thickness of the silica shell. A new computational method is presented and successfully applied to the segmentation of the core-shell nanoparticles, as one of the main problems in image analysis of the TEM micrographs. We have introduced the circularity coefficient, marked with k(circ) and defined as the ratio of circularity measure C-2(S) of nanoparticles core and circularity measure core-shell nanoparticles in order to answer the question how the shell affects the overall shape of the final core-shell structure, with respect to circularity. More precisely, the circularity coefficient determines whether the circularity of the core-shell nanoparticle is higher, lower or equal to the circularity of the core. We have also determined the shells share in the overall area of the core-shell nanoparticle. The core-shell nanoparticle clusters here investigated exhibit superparamagnetic properties at room temperature, thus emphasizing their potential for use in practical applications such as in biomedical and particle separation. We show that the saturation magnetization strength can be easily adjusted by controlling the thickness of the silica shell. (C) 2016 Elsevier Ltd and Techna Group S.r.l. All rights reserved. PB - Elsevier T2 - Ceramics International T1 - Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis EP - 10984 IS - 9 SP - 10976 VL - 42 DO - 10.1016/j.ceramint.2016.03.235 ER -
@article{ author = "Kopanja, Lazar and Kralj, Slavko and Žunić, Dragiša and Lončar, Boris B. and Tadić, Marin", year = "2016", abstract = "For the first time, particle shape analysis of silica coated iron oxide (maghemite/magnetite) nanoparticle clusters (core-shell nanostructures) is discussed using computational methods. We analyzed three samples of core-shell nanostructures synthesized with different thickness of the silica shell. A new computational method is presented and successfully applied to the segmentation of the core-shell nanoparticles, as one of the main problems in image analysis of the TEM micrographs. We have introduced the circularity coefficient, marked with k(circ) and defined as the ratio of circularity measure C-2(S) of nanoparticles core and circularity measure core-shell nanoparticles in order to answer the question how the shell affects the overall shape of the final core-shell structure, with respect to circularity. More precisely, the circularity coefficient determines whether the circularity of the core-shell nanoparticle is higher, lower or equal to the circularity of the core. We have also determined the shells share in the overall area of the core-shell nanoparticle. The core-shell nanoparticle clusters here investigated exhibit superparamagnetic properties at room temperature, thus emphasizing their potential for use in practical applications such as in biomedical and particle separation. We show that the saturation magnetization strength can be easily adjusted by controlling the thickness of the silica shell. (C) 2016 Elsevier Ltd and Techna Group S.r.l. All rights reserved.", publisher = "Elsevier", journal = "Ceramics International", title = "Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis", pages = "10984-10976", number = "9", volume = "42", doi = "10.1016/j.ceramint.2016.03.235" }
Kopanja, L., Kralj, S., Žunić, D., Lončar, B. B.,& Tadić, M.. (2016). Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis. in Ceramics International Elsevier., 42(9), 10976-10984. https://doi.org/10.1016/j.ceramint.2016.03.235
Kopanja L, Kralj S, Žunić D, Lončar BB, Tadić M. Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis. in Ceramics International. 2016;42(9):10976-10984. doi:10.1016/j.ceramint.2016.03.235 .
Kopanja, Lazar, Kralj, Slavko, Žunić, Dragiša, Lončar, Boris B., Tadić, Marin, "Core-shell superparamagnetic iron oxide nanoparticle (SPION) clusters: TEM micrograph analysis, particle design and shape analysis" in Ceramics International, 42, no. 9 (2016):10976-10984, https://doi.org/10.1016/j.ceramint.2016.03.235 . .