A novel and effective antibacterial agent based on a combination of copper nanoparticles (CuNPs) and polypyrrole (PPy) is presented. By using a straightforward in situ polymerization method in water, a copper/polypyrrole (Cu/PPy) nanocomposite with spherical CuNPs, around 25 nm in diameter, uniformly dispersed throughout a granular PPy matrix, was characterized and subjected to determination of antibacterial activity toward E. coli, and S. aureus. In this survey, the synergistic engagement of various features of CuNPs and PPy against bacteria was somewhat expected. After a 24 h interaction with S. aureus, already 2 ppm of Cu/PPy with only 9.45 wt% content of Cu is acting almost completely cidal, with 99.17 % bacterial growth inhibition, while 10 ppm has a cidal value of 99.99 % at the same time. Safe and environmentally acceptable concentrations of Cu/PPy indicate that it is convenient as an antibacterial agent for wider use.
TY - JOUR
AU - Mašojević, Dijana
AU - Stamenović, Una
AU - Otoničar, Mojca
AU - Davidović, Slađana
AU - Škapin, Srečo
AU - Barudžija, Tanja
AU - Vodnik, Vesna
PY - 2023
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5918
AB - A novel and effective antibacterial agent based on a combination of copper nanoparticles (CuNPs) and polypyrrole (PPy) is presented. By using a straightforward in situ polymerization method in water, a copper/polypyrrole (Cu/PPy) nanocomposite with spherical CuNPs, around 25 nm in diameter, uniformly dispersed throughout a granular PPy matrix, was characterized and subjected to determination of antibacterial activity toward E. coli, and S. aureus. In this survey, the synergistic engagement of various features of CuNPs and PPy against bacteria was somewhat expected. After a 24 h interaction with S. aureus, already 2 ppm of Cu/PPy with only 9.45 wt% content of Cu is acting almost completely cidal, with 99.17 % bacterial growth inhibition, while 10 ppm has a cidal value of 99.99 % at the same time. Safe and environmentally acceptable concentrations of Cu/PPy indicate that it is convenient as an antibacterial agent for wider use.
PB - Elsevier B.V.
T2 - Materials Letters
T1 - Evaluation of the antibacterial effectiveness of novel copper/polypyrrole nanocomposite
SP - 134051
VL - 338
DO - 10.1016/j.matlet.2023.134051
ER -
@article{
author = "Mašojević, Dijana and Stamenović, Una and Otoničar, Mojca and Davidović, Slađana and Škapin, Srečo and Barudžija, Tanja and Vodnik, Vesna",
year = "2023",
abstract = "A novel and effective antibacterial agent based on a combination of copper nanoparticles (CuNPs) and polypyrrole (PPy) is presented. By using a straightforward in situ polymerization method in water, a copper/polypyrrole (Cu/PPy) nanocomposite with spherical CuNPs, around 25 nm in diameter, uniformly dispersed throughout a granular PPy matrix, was characterized and subjected to determination of antibacterial activity toward E. coli, and S. aureus. In this survey, the synergistic engagement of various features of CuNPs and PPy against bacteria was somewhat expected. After a 24 h interaction with S. aureus, already 2 ppm of Cu/PPy with only 9.45 wt% content of Cu is acting almost completely cidal, with 99.17 % bacterial growth inhibition, while 10 ppm has a cidal value of 99.99 % at the same time. Safe and environmentally acceptable concentrations of Cu/PPy indicate that it is convenient as an antibacterial agent for wider use.",
publisher = "Elsevier B.V.",
journal = "Materials Letters",
title = "Evaluation of the antibacterial effectiveness of novel copper/polypyrrole nanocomposite",
pages = "134051",
volume = "338",
doi = "10.1016/j.matlet.2023.134051"
}
Mašojević, D., Stamenović, U., Otoničar, M., Davidović, S., Škapin, S., Barudžija, T.,& Vodnik, V.. (2023). Evaluation of the antibacterial effectiveness of novel copper/polypyrrole nanocomposite. in Materials Letters
Elsevier B.V.., 338, 134051.
https://doi.org/10.1016/j.matlet.2023.134051
Mašojević D, Stamenović U, Otoničar M, Davidović S, Škapin S, Barudžija T, Vodnik V. Evaluation of the antibacterial effectiveness of novel copper/polypyrrole nanocomposite. in Materials Letters. 2023;338:134051.
doi:10.1016/j.matlet.2023.134051 .
Mašojević, Dijana, Stamenović, Una, Otoničar, Mojca, Davidović, Slađana, Škapin, Srečo, Barudžija, Tanja, Vodnik, Vesna, "Evaluation of the antibacterial effectiveness of novel copper/polypyrrole nanocomposite" in Materials Letters, 338 (2023):134051,
https://doi.org/10.1016/j.matlet.2023.134051 . .
