A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds
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2023
Authors
Milovanović, StojaGrzegorczyk, Agnieszka
Świątek, Łukasz
Grzęda, Anita
Dębczak, Agnieszka
Tyskiewicz, Katarzyna
Konkol, Marcin
Article (Published version)

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The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils s...howed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food.
Keywords:
Antimicrobial activity / Antioxidant activity / Biological activity / Fatty acid composition / Linoleic acid / Total phenolic contentSource:
Food and Bioprocess Technology, 2023Publisher:
- Springer
Funding / projects:
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Milovanović, Stoja AU - Grzegorczyk, Agnieszka AU - Świątek, Łukasz AU - Grzęda, Anita AU - Dębczak, Agnieszka AU - Tyskiewicz, Katarzyna AU - Konkol, Marcin PY - 2023 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6031 AB - The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils showed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food. PB - Springer T2 - Food and Bioprocess Technology T1 - A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds DO - 10.1007/s11947-023-03038-9 ER -
@article{ author = "Milovanović, Stoja and Grzegorczyk, Agnieszka and Świątek, Łukasz and Grzęda, Anita and Dębczak, Agnieszka and Tyskiewicz, Katarzyna and Konkol, Marcin", year = "2023", abstract = "The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils showed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food.", publisher = "Springer", journal = "Food and Bioprocess Technology", title = "A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds", doi = "10.1007/s11947-023-03038-9" }
Milovanović, S., Grzegorczyk, A., Świątek, Ł., Grzęda, A., Dębczak, A., Tyskiewicz, K.,& Konkol, M.. (2023). A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds. in Food and Bioprocess Technology Springer.. https://doi.org/10.1007/s11947-023-03038-9
Milovanović S, Grzegorczyk A, Świątek Ł, Grzęda A, Dębczak A, Tyskiewicz K, Konkol M. A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds. in Food and Bioprocess Technology. 2023;. doi:10.1007/s11947-023-03038-9 .
Milovanović, Stoja, Grzegorczyk, Agnieszka, Świątek, Łukasz, Grzęda, Anita, Dębczak, Agnieszka, Tyskiewicz, Katarzyna, Konkol, Marcin, "A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds" in Food and Bioprocess Technology (2023), https://doi.org/10.1007/s11947-023-03038-9 . .