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A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds
dc.creator | Milovanović, Stoja | |
dc.creator | Grzegorczyk, Agnieszka | |
dc.creator | Świątek, Łukasz | |
dc.creator | Grzęda, Anita | |
dc.creator | Dębczak, Agnieszka | |
dc.creator | Tyskiewicz, Katarzyna | |
dc.creator | Konkol, Marcin | |
dc.date.accessioned | 2023-03-10T13:57:26Z | |
dc.date.available | 2023-03-10T13:57:26Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1935-5130 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6031 | |
dc.description.abstract | The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils showed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food. | sr |
dc.language.iso | en | sr |
dc.publisher | Springer | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200135/RS// | sr |
dc.rights | restrictedAccess | sr |
dc.source | Food and Bioprocess Technology | sr |
dc.subject | Antimicrobial activity | sr |
dc.subject | Antioxidant activity | sr |
dc.subject | Biological activity | sr |
dc.subject | Fatty acid composition | sr |
dc.subject | Linoleic acid | sr |
dc.subject | Total phenolic content | sr |
dc.title | A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds | sr |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dc.citation.rank | M21~ | |
dc.identifier.doi | 10.1007/s11947-023-03038-9 | |
dc.identifier.pmid | 37363382 | |
dc.identifier.scopus | 2-s2.0-85148943062 | |
dc.identifier.wos | 000941068100005 | |
dc.type.version | publishedVersion | sr |