In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method.
Keywords:
Carbendazim / Fruit juice / Ion trap / LC-MS/MS / Matrix effect / MSPD
Source:
Food Additives and Contaminants, 2005, 22, 11, 1132-1137
TY - JOUR
AU - Grujić, Svetlana
AU - Radišić, Marina
AU - Vasiljević, Tatjana
AU - Laušević, Mila
PY - 2005
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6052
AB - In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method.
PB - Taylor & Francis
T2 - Food Additives and Contaminants
T1 - Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry
EP - 1137
IS - 11
SP - 1132
VL - 22
DO - 10.1080/02652030500352863
ER -
@article{
author = "Grujić, Svetlana and Radišić, Marina and Vasiljević, Tatjana and Laušević, Mila",
year = "2005",
abstract = "In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method.",
publisher = "Taylor & Francis",
journal = "Food Additives and Contaminants",
title = "Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry",
pages = "1137-1132",
number = "11",
volume = "22",
doi = "10.1080/02652030500352863"
}
Grujić, S., Radišić, M., Vasiljević, T.,& Laušević, M.. (2005). Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry. in Food Additives and Contaminants
Taylor & Francis., 22(11), 1132-1137.
https://doi.org/10.1080/02652030500352863
Grujić S, Radišić M, Vasiljević T, Laušević M. Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry. in Food Additives and Contaminants. 2005;22(11):1132-1137.
doi:10.1080/02652030500352863 .
Grujić, Svetlana, Radišić, Marina, Vasiljević, Tatjana, Laušević, Mila, "Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry" in Food Additives and Contaminants, 22, no. 11 (2005):1132-1137,
https://doi.org/10.1080/02652030500352863 . .
