Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry
Abstract
In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method.
Keywords:
Carbendazim / Fruit juice / Ion trap / LC-MS/MS / Matrix effect / MSPDSource:
Food Additives and Contaminants, 2005, 22, 11, 1132-1137Publisher:
- Taylor & Francis
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Grujić, Svetlana AU - Radišić, Marina AU - Vasiljević, Tatjana AU - Laušević, Mila PY - 2005 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6052 AB - In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method. PB - Taylor & Francis T2 - Food Additives and Contaminants T1 - Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry EP - 1137 IS - 11 SP - 1132 VL - 22 DO - 10.1080/02652030500352863 ER -
@article{ author = "Grujić, Svetlana and Radišić, Marina and Vasiljević, Tatjana and Laušević, Mila", year = "2005", abstract = "In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD≤12%) and low limits of detection (0.03 ng ml -1 ) and quantification (0.1 ng ml -1 ) were achieved with this method.", publisher = "Taylor & Francis", journal = "Food Additives and Contaminants", title = "Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry", pages = "1137-1132", number = "11", volume = "22", doi = "10.1080/02652030500352863" }
Grujić, S., Radišić, M., Vasiljević, T.,& Laušević, M.. (2005). Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry. in Food Additives and Contaminants Taylor & Francis., 22(11), 1132-1137. https://doi.org/10.1080/02652030500352863
Grujić S, Radišić M, Vasiljević T, Laušević M. Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry. in Food Additives and Contaminants. 2005;22(11):1132-1137. doi:10.1080/02652030500352863 .
Grujić, Svetlana, Radišić, Marina, Vasiljević, Tatjana, Laušević, Mila, "Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry" in Food Additives and Contaminants, 22, no. 11 (2005):1132-1137, https://doi.org/10.1080/02652030500352863 . .