Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels
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Natural compounds found in different plant extracts can show numerous biological
activities and be used as health promoters. For instance, thymol, carvacrol,
citronellol, and eugenol (found in extracts of thyme, oregano, lemongrass, and clove,
respectively) can be used as anti-inflammatory, antiviral, and antimicrobial agents [1-
4]. The high volatility of the mentioned natural bioactive compounds (NBCs), which
restricts their broader application, can be managed by the incorporation of NBCs
into polymer matrices. Therefore, intending to develop devices that release
antimicrobial substances in a controlled manner, this study tested the applicability
of the supercritical solvent impregnation (SSI) technique for the incorporation of
NBCs into starch aerogels. First, the hydrogels were prepared from corn starch. The
water in the hydrogels was replaced by ethanol, and the obtained alcogels were dried
using the supercritical drying (SCD) technique. The parameters of the aerogels`
...
preparation were optimized previously [5].Later, SSI was performed at 150 bar and
35 °C for 2 h. The obtained materials were analyzed using FTIR, to determine the
potential interactions between the NBCs and polymer that could determine the rate
of controlled release and antimicrobial activity. Controlled release of NBCs from the
aerogels was tested in phosphate-buffered saline solution at 37 °C. ...
Source:
Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia, 2023, 163-165Publisher:
- Maribor : University of Maribor
- Maribor : University Press
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200135 (University of Belgrade, Faculty of Technology and Metallurgy) (RS-MESTD-inst-2020-200135)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200287 (Innovation Center of the Faculty of Technology and Metallurgy) (RS-MESTD-inst-2020-200287)
- COST Action "Advanced Engineering of aeroGels for Environment and Life Sciences" (AERoGELS, ref. CA18125), supported by COST (European Cooperation in Science and Technology)
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Tehnološko-metalurški fakultetTY - CONF AU - Milovanović, Stoja AU - Lukić, Ivana AU - Marković, Darka PY - 2023 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6792 AB - Natural compounds found in different plant extracts can show numerous biological activities and be used as health promoters. For instance, thymol, carvacrol, citronellol, and eugenol (found in extracts of thyme, oregano, lemongrass, and clove, respectively) can be used as anti-inflammatory, antiviral, and antimicrobial agents [1- 4]. The high volatility of the mentioned natural bioactive compounds (NBCs), which restricts their broader application, can be managed by the incorporation of NBCs into polymer matrices. Therefore, intending to develop devices that release antimicrobial substances in a controlled manner, this study tested the applicability of the supercritical solvent impregnation (SSI) technique for the incorporation of NBCs into starch aerogels. First, the hydrogels were prepared from corn starch. The water in the hydrogels was replaced by ethanol, and the obtained alcogels were dried using the supercritical drying (SCD) technique. The parameters of the aerogels` preparation were optimized previously [5].Later, SSI was performed at 150 bar and 35 °C for 2 h. The obtained materials were analyzed using FTIR, to determine the potential interactions between the NBCs and polymer that could determine the rate of controlled release and antimicrobial activity. Controlled release of NBCs from the aerogels was tested in phosphate-buffered saline solution at 37 °C. ... PB - Maribor : University of Maribor PB - Maribor : University Press C3 - Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia T1 - Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels EP - 165 SP - 163 UR - https://hdl.handle.net/21.15107/rcub_technorep_6792 ER -
@conference{ author = "Milovanović, Stoja and Lukić, Ivana and Marković, Darka", year = "2023", abstract = "Natural compounds found in different plant extracts can show numerous biological activities and be used as health promoters. For instance, thymol, carvacrol, citronellol, and eugenol (found in extracts of thyme, oregano, lemongrass, and clove, respectively) can be used as anti-inflammatory, antiviral, and antimicrobial agents [1- 4]. The high volatility of the mentioned natural bioactive compounds (NBCs), which restricts their broader application, can be managed by the incorporation of NBCs into polymer matrices. Therefore, intending to develop devices that release antimicrobial substances in a controlled manner, this study tested the applicability of the supercritical solvent impregnation (SSI) technique for the incorporation of NBCs into starch aerogels. First, the hydrogels were prepared from corn starch. The water in the hydrogels was replaced by ethanol, and the obtained alcogels were dried using the supercritical drying (SCD) technique. The parameters of the aerogels` preparation were optimized previously [5].Later, SSI was performed at 150 bar and 35 °C for 2 h. The obtained materials were analyzed using FTIR, to determine the potential interactions between the NBCs and polymer that could determine the rate of controlled release and antimicrobial activity. Controlled release of NBCs from the aerogels was tested in phosphate-buffered saline solution at 37 °C. ...", publisher = "Maribor : University of Maribor, Maribor : University Press", journal = "Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia", title = "Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels", pages = "165-163", url = "https://hdl.handle.net/21.15107/rcub_technorep_6792" }
Milovanović, S., Lukić, I.,& Marković, D.. (2023). Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels. in Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia Maribor : University of Maribor., 163-165. https://hdl.handle.net/21.15107/rcub_technorep_6792
Milovanović S, Lukić I, Marković D. Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels. in Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia. 2023;:163-165. https://hdl.handle.net/21.15107/rcub_technorep_6792 .
Milovanović, Stoja, Lukić, Ivana, Marković, Darka, "Supercritical Solvent Impregnation Technique for the Development of Antimicrobial Starch-based Aerogels" in Book of Abstracts / 3rd International Conference on Aerogels for Biomedical and Environmental Applications, 5–7 July 2023, Maribor, Slovenia (2023):163-165, https://hdl.handle.net/21.15107/rcub_technorep_6792 .