Alkylation of N-ethyl-2-phenylacetamide with benzyl halides
Apstrakt
Alkylations of N-ethyl-2-phenylacetamide with benzyl halides (chloride, bromide and iodide) in the presence of powdered KOH were carried out in order to establish the possible reaction products as well as to ascertain optimal reaction conditions for the synthesis of different products. Reactions were carried out in the presence of different phase-transfer catalysts, solvents and temperatures. N-, O-, C-and C,N-products of alkylation were established. Non-polar solvents were found to be the best for this type of reaction.
Ključne reči:
Alkylation / C,N-alkylation / C-alkylation / Mono-N-substituted phenylacetamides / N-alkylation / Phase-transfer catalysis / PhenylacetamidesIzvor:
Journal of the Serbian Chemical Society, 1996, 61, 12, 1137-1144Izdavač:
- Serbian Chemical Society, Belgrade
Institucija/grupa
Tehnološko-metalurški fakultetTY - JOUR AU - Mijin, Dušan AU - Božić, Biljana M. AU - Stojanović, N.D. AU - Petrović, Slobodan PY - 1996 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/72 AB - Alkylations of N-ethyl-2-phenylacetamide with benzyl halides (chloride, bromide and iodide) in the presence of powdered KOH were carried out in order to establish the possible reaction products as well as to ascertain optimal reaction conditions for the synthesis of different products. Reactions were carried out in the presence of different phase-transfer catalysts, solvents and temperatures. N-, O-, C-and C,N-products of alkylation were established. Non-polar solvents were found to be the best for this type of reaction. PB - Serbian Chemical Society, Belgrade T2 - Journal of the Serbian Chemical Society T1 - Alkylation of N-ethyl-2-phenylacetamide with benzyl halides EP - 1144 IS - 12 SP - 1137 VL - 61 UR - https://hdl.handle.net/21.15107/rcub_technorep_72 ER -
@article{ author = "Mijin, Dušan and Božić, Biljana M. and Stojanović, N.D. and Petrović, Slobodan", year = "1996", abstract = "Alkylations of N-ethyl-2-phenylacetamide with benzyl halides (chloride, bromide and iodide) in the presence of powdered KOH were carried out in order to establish the possible reaction products as well as to ascertain optimal reaction conditions for the synthesis of different products. Reactions were carried out in the presence of different phase-transfer catalysts, solvents and temperatures. N-, O-, C-and C,N-products of alkylation were established. Non-polar solvents were found to be the best for this type of reaction.", publisher = "Serbian Chemical Society, Belgrade", journal = "Journal of the Serbian Chemical Society", title = "Alkylation of N-ethyl-2-phenylacetamide with benzyl halides", pages = "1144-1137", number = "12", volume = "61", url = "https://hdl.handle.net/21.15107/rcub_technorep_72" }
Mijin, D., Božić, B. M., Stojanović, N.D.,& Petrović, S.. (1996). Alkylation of N-ethyl-2-phenylacetamide with benzyl halides. in Journal of the Serbian Chemical Society Serbian Chemical Society, Belgrade., 61(12), 1137-1144. https://hdl.handle.net/21.15107/rcub_technorep_72
Mijin D, Božić BM, Stojanović N, Petrović S. Alkylation of N-ethyl-2-phenylacetamide with benzyl halides. in Journal of the Serbian Chemical Society. 1996;61(12):1137-1144. https://hdl.handle.net/21.15107/rcub_technorep_72 .
Mijin, Dušan, Božić, Biljana M., Stojanović, N.D., Petrović, Slobodan, "Alkylation of N-ethyl-2-phenylacetamide with benzyl halides" in Journal of the Serbian Chemical Society, 61, no. 12 (1996):1137-1144, https://hdl.handle.net/21.15107/rcub_technorep_72 .
Related items
Showing items related by title, author, creator and subject.
-
Synthesis of substituted 3-cyano-2-pyridones: Part IV. Influence of 3-alkyl-2,4-pentanedione and N-alkyl cyanoacetamide structure on the enzyme catalyzed synthesis of substituted 3-cyano-2-pyridones
Mijin, Dušan; Milić, BD; Misić-Vuković, Milica (Natl Inst Science Communication, New Delhi, 2006) -
Alumina/silica aerogel with zinc chloride alkylation catalyst: Influence of supercritical drying conditions and aerogel structure on alkylation catalytic activity
Orlović, Aleksandar; Janaćković, Đorđe; Skala, Dejan (Elsevier, Amsterdam, 2002) -
Characterization of in situ prepared nanocomposites of PS and TIO2 nanoparticles surface modified with alkyl gallates: Effect of alkyl chain length
Džunuzović, Enis; Džunuzović, Jasna; Radoman, Tijana S.; Marinović-Cincović, Milena; Nikolić, Ljubiša B.; Jeremić, Katarina B.; Nedeljković, Jovan (Wiley, Hoboken, 2013)