Stability of liposomal particles with encapsulated coumarin derivate
Authors
Jovanović, Aleksandra A.Avdović, Edina
Plećić, Ana
Čutović, Natalija
Bugarski, Branko
Marković, Zoran
Conference object (Published version)
Metadata
Show full item recordAbstract
Coumarin derivates possess several biological effects, including anti-inflammatory, antioxidant, anticoagulant, antitumor, insecticidal, anthelminthic, hypnotic, antifungal, and HIV protease inhibition properties [1,2]. Due to their solubility in organic solvents and insolubility in water and body fluids, their bioavailability is significantlylow. Thus, they can be encapsulated intoliposomal particles with the aim of overcoming the mentioned disadvan-tage[3]. Hence, in the present study, coumarin derivate was encapsulated in phospholipid liposomes and their stability was monitored for 60 days in terms of vesicle size, polydispersity index (PDI), zeta potential, and mobility.
Keywords:
Liposomes / mobility / polydispersity index / vesicle size / zeta potentialSource:
Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts, 2024, 78, 1S, 66-Publisher:
- Savez hemijskih inženjera Srbije
Note:
- ExcellMater Conference 2024: Innovative Biomaterials for Novel Medical Devices, Belgrade, Serbia, April 10-12, 2024.
Institution/Community
Tehnološko-metalurški fakultetTY - CONF AU - Jovanović, Aleksandra A. AU - Avdović, Edina AU - Plećić, Ana AU - Čutović, Natalija AU - Bugarski, Branko AU - Marković, Zoran PY - 2024 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7440 AB - Coumarin derivates possess several biological effects, including anti-inflammatory, antioxidant, anticoagulant, antitumor, insecticidal, anthelminthic, hypnotic, antifungal, and HIV protease inhibition properties [1,2]. Due to their solubility in organic solvents and insolubility in water and body fluids, their bioavailability is significantlylow. Thus, they can be encapsulated intoliposomal particles with the aim of overcoming the mentioned disadvan-tage[3]. Hence, in the present study, coumarin derivate was encapsulated in phospholipid liposomes and their stability was monitored for 60 days in terms of vesicle size, polydispersity index (PDI), zeta potential, and mobility. PB - Savez hemijskih inženjera Srbije C3 - Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts T1 - Stability of liposomal particles with encapsulated coumarin derivate IS - 1S SP - 66 VL - 78 UR - https://hdl.handle.net/21.15107/rcub_technorep_7440 ER -
@conference{ author = "Jovanović, Aleksandra A. and Avdović, Edina and Plećić, Ana and Čutović, Natalija and Bugarski, Branko and Marković, Zoran", year = "2024", abstract = "Coumarin derivates possess several biological effects, including anti-inflammatory, antioxidant, anticoagulant, antitumor, insecticidal, anthelminthic, hypnotic, antifungal, and HIV protease inhibition properties [1,2]. Due to their solubility in organic solvents and insolubility in water and body fluids, their bioavailability is significantlylow. Thus, they can be encapsulated intoliposomal particles with the aim of overcoming the mentioned disadvan-tage[3]. Hence, in the present study, coumarin derivate was encapsulated in phospholipid liposomes and their stability was monitored for 60 days in terms of vesicle size, polydispersity index (PDI), zeta potential, and mobility.", publisher = "Savez hemijskih inženjera Srbije", journal = "Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts", title = "Stability of liposomal particles with encapsulated coumarin derivate", number = "1S", pages = "66", volume = "78", url = "https://hdl.handle.net/21.15107/rcub_technorep_7440" }
Jovanović, A. A., Avdović, E., Plećić, A., Čutović, N., Bugarski, B.,& Marković, Z.. (2024). Stability of liposomal particles with encapsulated coumarin derivate. in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts Savez hemijskih inženjera Srbije., 78(1S), 66. https://hdl.handle.net/21.15107/rcub_technorep_7440
Jovanović AA, Avdović E, Plećić A, Čutović N, Bugarski B, Marković Z. Stability of liposomal particles with encapsulated coumarin derivate. in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts. 2024;78(1S):66. https://hdl.handle.net/21.15107/rcub_technorep_7440 .
Jovanović, Aleksandra A., Avdović, Edina, Plećić, Ana, Čutović, Natalija, Bugarski, Branko, Marković, Zoran, "Stability of liposomal particles with encapsulated coumarin derivate" in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts, 78, no. 1S (2024):66, https://hdl.handle.net/21.15107/rcub_technorep_7440 .