RP TLC of some newly synthesized azo-dye derivatives
Апстракт
The chromatographic behavior of series of azo-dye derivatives has been studied by RP C-18 TLC with water-methanol, water-acetone, water-dioxane, and water-acetonitrile mobile phases. The mechanism of retention was investigated and the retention constants, R-M(0), were determined by extrapolation. Correlations between retention constants, R-M(0), and lipophificity, C-0 (C-0 = R-M(0)/m) and log P (ACD log P) were investigated. Better correlations were obtained between C-0 and log P than between R-M(0) and log P. These C-0 values may be use as a measure of the lipophilicity of the compounds investigated. The effect of mobile phase pH on retention of azo-dye derivatives was studied in RP C-18 TLC with diluted acetic acid-methanol, 20 + 30 (v/v) as mobile phase. Different methods were used to measure mobile phase pH. pK(a) values were determined on the basis of the relationships between analyte retention and mobile phase pH. Because the investigated azo dyes are newly synthesized compounds ...these pK(a) values have been determined for the first time. Correlations between pK(a) and log P are discussed.
Кључне речи:
azo dyes / RP TLC / chromatographic mechanism / correlation analysis / lipophilicity / effect of pHИзвор:
JPC-Journal of Planar Chromatography-Modern Tlc, 2006, 19, 108, 98-103Издавач:
- Akademiai Kiado Zrt, Budapest
DOI: 10.1556/JPC.19.2006.2.2
ISSN: 0933-4173
WoS: 000238267600002
Scopus: 2-s2.0-33744963807
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Perišić-Janjić, Nada AU - Ušćumlić, Gordana AU - Mijin, Dušan PY - 2006 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/921 AB - The chromatographic behavior of series of azo-dye derivatives has been studied by RP C-18 TLC with water-methanol, water-acetone, water-dioxane, and water-acetonitrile mobile phases. The mechanism of retention was investigated and the retention constants, R-M(0), were determined by extrapolation. Correlations between retention constants, R-M(0), and lipophificity, C-0 (C-0 = R-M(0)/m) and log P (ACD log P) were investigated. Better correlations were obtained between C-0 and log P than between R-M(0) and log P. These C-0 values may be use as a measure of the lipophilicity of the compounds investigated. The effect of mobile phase pH on retention of azo-dye derivatives was studied in RP C-18 TLC with diluted acetic acid-methanol, 20 + 30 (v/v) as mobile phase. Different methods were used to measure mobile phase pH. pK(a) values were determined on the basis of the relationships between analyte retention and mobile phase pH. Because the investigated azo dyes are newly synthesized compounds these pK(a) values have been determined for the first time. Correlations between pK(a) and log P are discussed. PB - Akademiai Kiado Zrt, Budapest T2 - JPC-Journal of Planar Chromatography-Modern Tlc T1 - RP TLC of some newly synthesized azo-dye derivatives EP - 103 IS - 108 SP - 98 VL - 19 DO - 10.1556/JPC.19.2006.2.2 ER -
@article{ author = "Perišić-Janjić, Nada and Ušćumlić, Gordana and Mijin, Dušan", year = "2006", abstract = "The chromatographic behavior of series of azo-dye derivatives has been studied by RP C-18 TLC with water-methanol, water-acetone, water-dioxane, and water-acetonitrile mobile phases. The mechanism of retention was investigated and the retention constants, R-M(0), were determined by extrapolation. Correlations between retention constants, R-M(0), and lipophificity, C-0 (C-0 = R-M(0)/m) and log P (ACD log P) were investigated. Better correlations were obtained between C-0 and log P than between R-M(0) and log P. These C-0 values may be use as a measure of the lipophilicity of the compounds investigated. The effect of mobile phase pH on retention of azo-dye derivatives was studied in RP C-18 TLC with diluted acetic acid-methanol, 20 + 30 (v/v) as mobile phase. Different methods were used to measure mobile phase pH. pK(a) values were determined on the basis of the relationships between analyte retention and mobile phase pH. Because the investigated azo dyes are newly synthesized compounds these pK(a) values have been determined for the first time. Correlations between pK(a) and log P are discussed.", publisher = "Akademiai Kiado Zrt, Budapest", journal = "JPC-Journal of Planar Chromatography-Modern Tlc", title = "RP TLC of some newly synthesized azo-dye derivatives", pages = "103-98", number = "108", volume = "19", doi = "10.1556/JPC.19.2006.2.2" }
Perišić-Janjić, N., Ušćumlić, G.,& Mijin, D.. (2006). RP TLC of some newly synthesized azo-dye derivatives. in JPC-Journal of Planar Chromatography-Modern Tlc Akademiai Kiado Zrt, Budapest., 19(108), 98-103. https://doi.org/10.1556/JPC.19.2006.2.2
Perišić-Janjić N, Ušćumlić G, Mijin D. RP TLC of some newly synthesized azo-dye derivatives. in JPC-Journal of Planar Chromatography-Modern Tlc. 2006;19(108):98-103. doi:10.1556/JPC.19.2006.2.2 .
Perišić-Janjić, Nada, Ušćumlić, Gordana, Mijin, Dušan, "RP TLC of some newly synthesized azo-dye derivatives" in JPC-Journal of Planar Chromatography-Modern Tlc, 19, no. 108 (2006):98-103, https://doi.org/10.1556/JPC.19.2006.2.2 . .