Приказ основних података о документу

dc.creatorManojlović, Verica
dc.creatorĐonlagić, Jasna
dc.creatorObradović, Bojana
dc.creatorNedović, Viktor
dc.creatorBugarski, Branko
dc.date.accessioned2021-03-10T10:32:54Z
dc.date.available2021-03-10T10:32:54Z
dc.date.issued2006
dc.identifier.issn0268-2575
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/929
dc.description.abstractIn this study, the process of electrostatic extrusion as a method for cell immobilization was investigated. We have assessed the effects of concentrations of yeast cells (as a model cell type) and Na alginate on the size of the resulting microbeads and attempted to rationalize the obtained findings by rheological characterization of the cell-alginate suspensions. Under the investigated conditions, microbeads, 50-600 mu m in diameter, were produced and the increase in both alginate and cell concentrations resulted in larger microbeads with their sizes having higher standard deviations. Rheological characterization revealed non-Newtonian, pseudoplastic behavior of cell-alginate suspensions with higher viscosities at higher alginate concentrations. However, the presence of cells even at high concentrations (5 x 10(8) and 1 x 10(9) cells mL(-1)) did not significantly affect the rheological properties of the Na alginate solution. Finally, we have investigated the kinetics of alginate gelation with respect to the quantity of Ca2+ ions and the presence of cells. The molar ratio of alpha-L-guluronic acid units to Ca2+ ions of 4:1 provided complete crosslinking. The presence of cells decreased the rate of network formation as well as the strength of the obtained Ca alginate hydrogel.en
dc.publisherWiley, Hoboken
dc.rightsopenAccess
dc.sourceJournal of Chemical Technology and Biotechnology
dc.subjectcell immobilizationen
dc.subjectrheologyen
dc.subjectalginateen
dc.subjectelectrostatic extrusionen
dc.titleInvestigations of cell immobilization in alginate: rheological and electrostatic extrusion studiesen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage510
dc.citation.issue4
dc.citation.other81(4): 505-510
dc.citation.rankM21
dc.citation.spage505
dc.citation.volume81
dc.identifier.doi10.1002/jctb.1465
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/2375/926.pdf
dc.identifier.scopus2-s2.0-33646205685
dc.identifier.wos000236946500005
dc.type.versionpublishedVersion


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