TY  - BOOK
AU  - Tadić, Vanja
AU  - Maksimović, Svetolik
AU  - Nešić, Ivana
AU  - Žižović, Irena
AU  - Mišić, Dušan
AU  - Milovanović, Stoja
AU  - Žugić, Ana
AU  - Aksentijević, Ksenija
AU  - Stanković, Milica
AU  - Ivanović, Jasna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6876
PB  - Niš : Galaksijanis
T1  - Smilje od tradicionalne do naučno zasnovane primene
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6876
ER  - 

@book{
author = "Tadić, Vanja and Maksimović, Svetolik and Nešić, Ivana and Žižović, Irena and Mišić, Dušan and Milovanović, Stoja and Žugić, Ana and Aksentijević, Ksenija and Stanković, Milica and Ivanović, Jasna",
year = "2021",
publisher = "Niš : Galaksijanis",
title = "Smilje od tradicionalne do naučno zasnovane primene",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6876"
}

Tadić, V., Maksimović, S., Nešić, I., Žižović, I., Mišić, D., Milovanović, S., Žugić, A., Aksentijević, K., Stanković, M.,& Ivanović, J.. (2021). Smilje od tradicionalne do naučno zasnovane primene. 
Niš : Galaksijanis..
https://hdl.handle.net/21.15107/rcub_technorep_6876

Tadić V, Maksimović S, Nešić I, Žižović I, Mišić D, Milovanović S, Žugić A, Aksentijević K, Stanković M, Ivanović J. Smilje od tradicionalne do naučno zasnovane primene. 2021;.
https://hdl.handle.net/21.15107/rcub_technorep_6876 .

Tadić, Vanja, Maksimović, Svetolik, Nešić, Ivana, Žižović, Irena, Mišić, Dušan, Milovanović, Stoja, Žugić, Ana, Aksentijević, Ksenija, Stanković, Milica, Ivanović, Jasna, "Smilje od tradicionalne do naučno zasnovane primene" (2021),
https://hdl.handle.net/21.15107/rcub_technorep_6876 .

TY  - JOUR
AU  - Malićanin, Marko
AU  - Milanović, Jelena
AU  - Žižović, Irena
AU  - Ivanović, Jasna
AU  - Milovanović, Stoja
AU  - Rakić, Vesna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6877
AB  - In this work, the extraction by supercritical carbon dioxide of grapeseed oil from five red grape varieties was investigated. Apart from an indigenous variety Prokupac, as the domestic, and Merlot and Cabernet Sauvignon, as international grape varieties the most represented in the Republic of Serbia, Pinot Noir and Gamay were studied as well. Extraction conditions were: temperature of 50 °C, 250 bar pressure, and 0.3 kg/h flow rate of CO2. It was shown that the extraction kinetics of international grape varieties, mutually similar differ significantly from the domestic one. The obtained oil yields were in the range of 8.3% w/w (Gamay) to 10.4% w/w (Pinot Noir) for the international varieties and 5.0% w/w for the domestic variety. The mathematical model “Sovova” was applied to define transport parameters regulating the oil mass transfer inside the seed particles and determine the agreement between experimental and model curves. The interpretation of results took into account the differences of grade seed morphologies (outer surfaces and inner layers) which was investigated by SEM analysis.
AB  - U ovom radu je ekstrakcija natkritičnim ugljen-dioksidom primenjena za dobijanje ulja iz
semenki crvenih sorti grožđa koje su najzastupljenije u Republici Srbiji, od kojih je sorta Prokupac
autohtona, a ostale sorte su internacionalne. Ekstrakcija je izvedena na temperaturi od 50 °C,
pritisku od 250 bar i protoku od 0,3 kg CO2 /h. Pokazano je da je kinetika ekstrakcije slična za
internacionalne sorte grožđa, a da se značajno razlikuje od kinetike ekstrakcije ulja iz autohtone
sorte Prokupac. Prinosi ulja su se kod internacionalnih sorti grožđa kretali od 8,3% (Game) do
10,4% w/w (Pinot Noir), dok je kod domaće sorte Prokupac ostvaren prinos od 4,96% w/w. Za
definisanje parametara ekstrakcije koji regulišu transport mase unutar čestica semenki primenjen
je matematički model “Sovova”. Snimanje unutrašnje i spoljašnje morfologije semenki SEM
metodom je korišćeno za interpretaciju rezultata dobijenih primenom matematičkog modela.
PB  - University of Niš, Serbia
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters
T1  - Ekstrakcija ulja iz semenki crvenih sorti grožđa natkritičnim CO2. Prinosi i parametri ekstrakcije
EP  - 56
IS  - 1
SP  - 45
VL  - 19
DO  - 10.2298/FUPCT2101045M
ER  - 

@article{
author = "Malićanin, Marko and Milanović, Jelena and Žižović, Irena and Ivanović, Jasna and Milovanović, Stoja and Rakić, Vesna",
year = "2021",
abstract = "In this work, the extraction by supercritical carbon dioxide of grapeseed oil from five red grape varieties was investigated. Apart from an indigenous variety Prokupac, as the domestic, and Merlot and Cabernet Sauvignon, as international grape varieties the most represented in the Republic of Serbia, Pinot Noir and Gamay were studied as well. Extraction conditions were: temperature of 50 °C, 250 bar pressure, and 0.3 kg/h flow rate of CO2. It was shown that the extraction kinetics of international grape varieties, mutually similar differ significantly from the domestic one. The obtained oil yields were in the range of 8.3% w/w (Gamay) to 10.4% w/w (Pinot Noir) for the international varieties and 5.0% w/w for the domestic variety. The mathematical model “Sovova” was applied to define transport parameters regulating the oil mass transfer inside the seed particles and determine the agreement between experimental and model curves. The interpretation of results took into account the differences of grade seed morphologies (outer surfaces and inner layers) which was investigated by SEM analysis., U ovom radu je ekstrakcija natkritičnim ugljen-dioksidom primenjena za dobijanje ulja iz
semenki crvenih sorti grožđa koje su najzastupljenije u Republici Srbiji, od kojih je sorta Prokupac
autohtona, a ostale sorte su internacionalne. Ekstrakcija je izvedena na temperaturi od 50 °C,
pritisku od 250 bar i protoku od 0,3 kg CO2 /h. Pokazano je da je kinetika ekstrakcije slična za
internacionalne sorte grožđa, a da se značajno razlikuje od kinetike ekstrakcije ulja iz autohtone
sorte Prokupac. Prinosi ulja su se kod internacionalnih sorti grožđa kretali od 8,3% (Game) do
10,4% w/w (Pinot Noir), dok je kod domaće sorte Prokupac ostvaren prinos od 4,96% w/w. Za
definisanje parametara ekstrakcije koji regulišu transport mase unutar čestica semenki primenjen
je matematički model “Sovova”. Snimanje unutrašnje i spoljašnje morfologije semenki SEM
metodom je korišćeno za interpretaciju rezultata dobijenih primenom matematičkog modela.",
publisher = "University of Niš, Serbia",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters, Ekstrakcija ulja iz semenki crvenih sorti grožđa natkritičnim CO2. Prinosi i parametri ekstrakcije",
pages = "56-45",
number = "1",
volume = "19",
doi = "10.2298/FUPCT2101045M"
}

Malićanin, M., Milanović, J., Žižović, I., Ivanović, J., Milovanović, S.,& Rakić, V.. (2021). SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters. in Facta Universitatis, Series: Physics, Chemistry and Technology
University of Niš, Serbia., 19(1), 45-56.
https://doi.org/10.2298/FUPCT2101045M

Malićanin M, Milanović J, Žižović I, Ivanović J, Milovanović S, Rakić V. SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2021;19(1):45-56.
doi:10.2298/FUPCT2101045M .

Malićanin, Marko, Milanović, Jelena, Žižović, Irena, Ivanović, Jasna, Milovanović, Stoja, Rakić, Vesna, "SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters" in Facta Universitatis, Series: Physics, Chemistry and Technology, 19, no. 1 (2021):45-56,
https://doi.org/10.2298/FUPCT2101045M . .

TY  - JOUR
AU  - Milanović, Jelena
AU  - Malićanin, Marko
AU  - Žižović, Irena
AU  - Ivanović, Jasna
AU  - Milovanović, Stoja
AU  - Rakić, Vesna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6878
AB  - This study aimed to investigate the potential of the most abundant red grape variety from the central part of Serbia (the region of three Morava rivers) for grape oil manufacturing, using supercritical CO2 extraction. The content of the main constituents of grape seed oils from the indigenous variety Prokupac was determined and the results
of the analysis were compared with selected, most commonly grown, international varieties (Cabernet Sauvignon, Pinot Noir, Merlot, and Gamay). Fatty acid profile and the content of biologically active compounds (total phenolic compounds and αtocopherol) were determined. Oxidative stability of the oils was estimated using a DSC
(differential scanning calorimetry) method, by determining the oxidation onset temperature. The fatty acid composition was in accordance with literature data. In terms of α-tocopherol content, its low relative amount was measured in the oils from all grape seed varieties.
AB  - Cilj ovog rada je ispitivanje potencijala za dobijanje ulja iz semenki grožđa najzastupljenijih
crvenih sorti grožđa u centralnom delu Republike Srbije (oblast tri Morave), primenom natkritične
CO2 ekstrakcije. U radu je izvršena karakterizacija glavnih sastojaka semenki autohtone sorte
Prokupac i poređenje sastava ovog ulja sa uljima izolovanih iz semenki najzastupljenijih
internacionalnih sorti grožđa u ovom regionu. Određen je masnokiselinski sastav ulja, sadržaj
ukupnih fenolnih jedinjenja i sadržaj α-tokoferola. Za određivanje oksidativne stabilnosti ulja
upotrebljena je DSC metoda. Sastav masnih kiselina u uljima bio je u skladu sa podacima iz
literature. Utvrđeno je da se od svih sorti grožđa primenjenim uslovima ekstrakcije dobijaju ulja sa
niskim sadržajem α-tokoferola.
PB  - University of Niš, Serbia
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - Chemical composition of seed oil from red grape varieties obtained by supercritical CO2 extraction
T1  - Hemijski sastav ulja semenki crvenih sorti grožđa izolovanih natkritičnom CO2 ekstrakcijom
EP  - 90
IS  - 2
SP  - 81
VL  - 19
DO  - 10.2298/FUPCT2102081M
ER  - 

@article{
author = "Milanović, Jelena and Malićanin, Marko and Žižović, Irena and Ivanović, Jasna and Milovanović, Stoja and Rakić, Vesna",
year = "2021",
abstract = "This study aimed to investigate the potential of the most abundant red grape variety from the central part of Serbia (the region of three Morava rivers) for grape oil manufacturing, using supercritical CO2 extraction. The content of the main constituents of grape seed oils from the indigenous variety Prokupac was determined and the results
of the analysis were compared with selected, most commonly grown, international varieties (Cabernet Sauvignon, Pinot Noir, Merlot, and Gamay). Fatty acid profile and the content of biologically active compounds (total phenolic compounds and αtocopherol) were determined. Oxidative stability of the oils was estimated using a DSC
(differential scanning calorimetry) method, by determining the oxidation onset temperature. The fatty acid composition was in accordance with literature data. In terms of α-tocopherol content, its low relative amount was measured in the oils from all grape seed varieties., Cilj ovog rada je ispitivanje potencijala za dobijanje ulja iz semenki grožđa najzastupljenijih
crvenih sorti grožđa u centralnom delu Republike Srbije (oblast tri Morave), primenom natkritične
CO2 ekstrakcije. U radu je izvršena karakterizacija glavnih sastojaka semenki autohtone sorte
Prokupac i poređenje sastava ovog ulja sa uljima izolovanih iz semenki najzastupljenijih
internacionalnih sorti grožđa u ovom regionu. Određen je masnokiselinski sastav ulja, sadržaj
ukupnih fenolnih jedinjenja i sadržaj α-tokoferola. Za određivanje oksidativne stabilnosti ulja
upotrebljena je DSC metoda. Sastav masnih kiselina u uljima bio je u skladu sa podacima iz
literature. Utvrđeno je da se od svih sorti grožđa primenjenim uslovima ekstrakcije dobijaju ulja sa
niskim sadržajem α-tokoferola.",
publisher = "University of Niš, Serbia",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "Chemical composition of seed oil from red grape varieties obtained by supercritical CO2 extraction, Hemijski sastav ulja semenki crvenih sorti grožđa izolovanih natkritičnom CO2 ekstrakcijom",
pages = "90-81",
number = "2",
volume = "19",
doi = "10.2298/FUPCT2102081M"
}

Milanović, J., Malićanin, M., Žižović, I., Ivanović, J., Milovanović, S.,& Rakić, V.. (2021). Chemical composition of seed oil from red grape varieties obtained by supercritical CO2 extraction. in Facta Universitatis, Series: Physics, Chemistry and Technology
University of Niš, Serbia., 19(2), 81-90.
https://doi.org/10.2298/FUPCT2102081M

Milanović J, Malićanin M, Žižović I, Ivanović J, Milovanović S, Rakić V. Chemical composition of seed oil from red grape varieties obtained by supercritical CO2 extraction. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2021;19(2):81-90.
doi:10.2298/FUPCT2102081M .

Milanović, Jelena, Malićanin, Marko, Žižović, Irena, Ivanović, Jasna, Milovanović, Stoja, Rakić, Vesna, "Chemical composition of seed oil from red grape varieties obtained by supercritical CO2 extraction" in Facta Universitatis, Series: Physics, Chemistry and Technology, 19, no. 2 (2021):81-90,
https://doi.org/10.2298/FUPCT2102081M . .

TY  - CONF
AU  - Maksimović, Svetolik
AU  - Milovanović, Stoja
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6896
AB  - The coupling of supercritical fluid extraction and supercritical solvent impregnation processes has been proved to be convenient in cases where the active substance, to be incorporated in the solid carrier, is supercritical extract. The integrated process enables minimizing the loss of the extract by directly using the supercritical CO2-extract solution leaving the extractor vessel for the impregnation and avoidance of the intermediate decompression step in the separate processes (decompression after extraction), and consequently leads to energy and time savings.
The objective of this work was to examine the application of the integrated process for impregnation of chitosan/alginate and corn starch xerogels and aerogels with Helichrysum italicum supercritical CO2 extract. For that purpose, first chitosan/alginate and starch hydrogels were prepared by sol-gel method. Thereafter hydrogels were transformed into alcogels by water exchange with ethanol or acetone. Xerogels and aerogels were produced by air and supercritical CO2 drying of the alcogels or acetogels, respectively. Finally, impregnation of the xerogels and aerogels was performed in the laboratory unit for the integrated processes.
Both chitosan/alginate and starch xerogels and aerogels showed significant affinity for the incorporation of active principles from H. italicum which was confirmed by FTIR method. SEM method indicated significant differences in materials’ porosity. One of the reason for this is pore collapse phenomenon associated the formation of the xerogels. Obtained results confirmed that it is possible to impregnate chitosan/alginate and starch xerogels and aerogels with H. italicum extract by the integrated process of supercritical CO2 extraction and impregnation.
C3  - 18th European Meeting of Supercritical fluids (EMSF), 3-6 May 2021, Bordeaux, France
T1  - The integrated process of supercritical CO2 extraction from Helichrysum italicum and supercritical impregnation of biocompatible polymers with the obtained extract
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6896
ER  - 

@conference{
author = "Maksimović, Svetolik and Milovanović, Stoja and Ivanović, Jasna and Žižović, Irena",
year = "2021",
abstract = "The coupling of supercritical fluid extraction and supercritical solvent impregnation processes has been proved to be convenient in cases where the active substance, to be incorporated in the solid carrier, is supercritical extract. The integrated process enables minimizing the loss of the extract by directly using the supercritical CO2-extract solution leaving the extractor vessel for the impregnation and avoidance of the intermediate decompression step in the separate processes (decompression after extraction), and consequently leads to energy and time savings.
The objective of this work was to examine the application of the integrated process for impregnation of chitosan/alginate and corn starch xerogels and aerogels with Helichrysum italicum supercritical CO2 extract. For that purpose, first chitosan/alginate and starch hydrogels were prepared by sol-gel method. Thereafter hydrogels were transformed into alcogels by water exchange with ethanol or acetone. Xerogels and aerogels were produced by air and supercritical CO2 drying of the alcogels or acetogels, respectively. Finally, impregnation of the xerogels and aerogels was performed in the laboratory unit for the integrated processes.
Both chitosan/alginate and starch xerogels and aerogels showed significant affinity for the incorporation of active principles from H. italicum which was confirmed by FTIR method. SEM method indicated significant differences in materials’ porosity. One of the reason for this is pore collapse phenomenon associated the formation of the xerogels. Obtained results confirmed that it is possible to impregnate chitosan/alginate and starch xerogels and aerogels with H. italicum extract by the integrated process of supercritical CO2 extraction and impregnation.",
journal = "18th European Meeting of Supercritical fluids (EMSF), 3-6 May 2021, Bordeaux, France",
title = "The integrated process of supercritical CO2 extraction from Helichrysum italicum and supercritical impregnation of biocompatible polymers with the obtained extract",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6896"
}

Maksimović, S., Milovanović, S., Ivanović, J.,& Žižović, I.. (2021). The integrated process of supercritical CO2 extraction from Helichrysum italicum and supercritical impregnation of biocompatible polymers with the obtained extract. in 18th European Meeting of Supercritical fluids (EMSF), 3-6 May 2021, Bordeaux, France.
https://hdl.handle.net/21.15107/rcub_technorep_6896

Maksimović S, Milovanović S, Ivanović J, Žižović I. The integrated process of supercritical CO2 extraction from Helichrysum italicum and supercritical impregnation of biocompatible polymers with the obtained extract. in 18th European Meeting of Supercritical fluids (EMSF), 3-6 May 2021, Bordeaux, France. 2021;.
https://hdl.handle.net/21.15107/rcub_technorep_6896 .

Maksimović, Svetolik, Milovanović, Stoja, Ivanović, Jasna, Žižović, Irena, "The integrated process of supercritical CO2 extraction from Helichrysum italicum and supercritical impregnation of biocompatible polymers with the obtained extract" in 18th European Meeting of Supercritical fluids (EMSF), 3-6 May 2021, Bordeaux, France (2021),
https://hdl.handle.net/21.15107/rcub_technorep_6896 .

TY  - JOUR
AU  - Lukić, Ivana
AU  - Vulić, Jelena
AU  - Ivanović, Jasna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4561
AB  - Present study was aimed to produce biodegradable films with antioxidant activity for active food packaging. Films of poly(lactic acid) (PLA) with 5 wt% of poly(ε-caprolactone) (PCL), denoted as PLA-5, were loaded with thymol, carvacrol and their mixture using supercritical CO2 at 40 °C and 10 MPa for 5 h, with 27.53, 21.18, and 21.49 % of loading achieved, respectively. Morphological, structural and mechanical properties of the obtained PLA-5 films were analyzed. The highest total polyphenol content and the best antioxidant activity as well as good storage stability, acceptable physical properties and the lowest release rate (44.51 mg/L released after 6 weeks) were observed for PLA-5 film loaded with thymol and carvacrol mixture. Mixture of thymol and carvacrol loaded into PLA-5 film showed synergy and low percentage of migration into distilled water, revealing great potential for application as a food packaging material with aim to decrease requirements for amount of the active ingredients.
T2  - Food Packaging and Shelf Life
T1  - Antioxidant activity of PLA/PCL films loaded with thymol and/or carvacrol using scCO2 for active food packaging
VL  - 26
DO  - 10.1016/j.fpsl.2020.100578
ER  - 

@article{
author = "Lukić, Ivana and Vulić, Jelena and Ivanović, Jasna",
year = "2020",
abstract = "Present study was aimed to produce biodegradable films with antioxidant activity for active food packaging. Films of poly(lactic acid) (PLA) with 5 wt% of poly(ε-caprolactone) (PCL), denoted as PLA-5, were loaded with thymol, carvacrol and their mixture using supercritical CO2 at 40 °C and 10 MPa for 5 h, with 27.53, 21.18, and 21.49 % of loading achieved, respectively. Morphological, structural and mechanical properties of the obtained PLA-5 films were analyzed. The highest total polyphenol content and the best antioxidant activity as well as good storage stability, acceptable physical properties and the lowest release rate (44.51 mg/L released after 6 weeks) were observed for PLA-5 film loaded with thymol and carvacrol mixture. Mixture of thymol and carvacrol loaded into PLA-5 film showed synergy and low percentage of migration into distilled water, revealing great potential for application as a food packaging material with aim to decrease requirements for amount of the active ingredients.",
journal = "Food Packaging and Shelf Life",
title = "Antioxidant activity of PLA/PCL films loaded with thymol and/or carvacrol using scCO2 for active food packaging",
volume = "26",
doi = "10.1016/j.fpsl.2020.100578"
}

Lukić, I., Vulić, J.,& Ivanović, J.. (2020). Antioxidant activity of PLA/PCL films loaded with thymol and/or carvacrol using scCO2 for active food packaging. in Food Packaging and Shelf Life, 26.
https://doi.org/10.1016/j.fpsl.2020.100578

Lukić I, Vulić J, Ivanović J. Antioxidant activity of PLA/PCL films loaded with thymol and/or carvacrol using scCO2 for active food packaging. in Food Packaging and Shelf Life. 2020;26.
doi:10.1016/j.fpsl.2020.100578 .

Lukić, Ivana, Vulić, Jelena, Ivanović, Jasna, "Antioxidant activity of PLA/PCL films loaded with thymol and/or carvacrol using scCO2 for active food packaging" in Food Packaging and Shelf Life, 26 (2020),
https://doi.org/10.1016/j.fpsl.2020.100578 . .

TY  - JOUR
AU  - Krivokapić, Jovana
AU  - Ivanović, Jasna
AU  - Đuriš, Jelena
AU  - Medarević, Đorđe
AU  - Potpara, Zorica
AU  - Maksimović, Zoran
AU  - Ibrić, Svetlana
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5900
AB  - The objective of this work was to study the relation between the manufacturing conditions of microcrystalline cellulose (MCC), its physicochemical properties and its tableting behavior. Two different preparation procedures were used to produce MCC from wheat straw, utilizing an acid hydrolysis method, either using only sulfuric acid or combination of sulfuric and hydrochloric acid. The tableting behavior of obtained MCC samples and mixtures of MCC with ibuprofen was studied using a dynamic powder compaction analyzer. It was observed that some of the obtained MCC samples showed better flowing properties than commercially available Vivapur® PH101 and also very high values of tensile strength, solid fraction and elastic recovery. This can be linked with its good compaction behavior, but on the other hand it can cause problems with the disintegration of the tablets. In mixtures with ibuprofen, MCC samples showed lower values of tensile strength, while on the other hand elastic recovery did not seem to be much affected, still exhibiting very high values. According to the obtained results, it can be concluded that MCC obtained from the agricultural waste could have satisfactory properties for tablet preparation by the direct compression method. Further studies are needed to optimize process conditions in order to achieve better physicochemical characteristics, especially in terms of elastic recovery.
PB  - Elsevier B.V.
T2  - Saudi Pharmaceutical Journal
T1  - Tableting properties of microcrystalline cellulose obtained from wheat straw measured with a single punch bench top tablet press
EP  - 718
SP  - 710
VL  - 2
DO  - 10.1016/j.jsps.2020.04.013
ER  - 

@article{
author = "Krivokapić, Jovana and Ivanović, Jasna and Đuriš, Jelena and Medarević, Đorđe and Potpara, Zorica and Maksimović, Zoran and Ibrić, Svetlana",
year = "2020",
abstract = "The objective of this work was to study the relation between the manufacturing conditions of microcrystalline cellulose (MCC), its physicochemical properties and its tableting behavior. Two different preparation procedures were used to produce MCC from wheat straw, utilizing an acid hydrolysis method, either using only sulfuric acid or combination of sulfuric and hydrochloric acid. The tableting behavior of obtained MCC samples and mixtures of MCC with ibuprofen was studied using a dynamic powder compaction analyzer. It was observed that some of the obtained MCC samples showed better flowing properties than commercially available Vivapur® PH101 and also very high values of tensile strength, solid fraction and elastic recovery. This can be linked with its good compaction behavior, but on the other hand it can cause problems with the disintegration of the tablets. In mixtures with ibuprofen, MCC samples showed lower values of tensile strength, while on the other hand elastic recovery did not seem to be much affected, still exhibiting very high values. According to the obtained results, it can be concluded that MCC obtained from the agricultural waste could have satisfactory properties for tablet preparation by the direct compression method. Further studies are needed to optimize process conditions in order to achieve better physicochemical characteristics, especially in terms of elastic recovery.",
publisher = "Elsevier B.V.",
journal = "Saudi Pharmaceutical Journal",
title = "Tableting properties of microcrystalline cellulose obtained from wheat straw measured with a single punch bench top tablet press",
pages = "718-710",
volume = "2",
doi = "10.1016/j.jsps.2020.04.013"
}

Krivokapić, J., Ivanović, J., Đuriš, J., Medarević, Đ., Potpara, Z., Maksimović, Z.,& Ibrić, S.. (2020). Tableting properties of microcrystalline cellulose obtained from wheat straw measured with a single punch bench top tablet press. in Saudi Pharmaceutical Journal
Elsevier B.V.., 2, 710-718.
https://doi.org/10.1016/j.jsps.2020.04.013

Krivokapić J, Ivanović J, Đuriš J, Medarević Đ, Potpara Z, Maksimović Z, Ibrić S. Tableting properties of microcrystalline cellulose obtained from wheat straw measured with a single punch bench top tablet press. in Saudi Pharmaceutical Journal. 2020;2:710-718.
doi:10.1016/j.jsps.2020.04.013 .

Krivokapić, Jovana, Ivanović, Jasna, Đuriš, Jelena, Medarević, Đorđe, Potpara, Zorica, Maksimović, Zoran, Ibrić, Svetlana, "Tableting properties of microcrystalline cellulose obtained from wheat straw measured with a single punch bench top tablet press" in Saudi Pharmaceutical Journal, 2 (2020):710-718,
https://doi.org/10.1016/j.jsps.2020.04.013 . .

TY  - JOUR
AU  - Kuska, Robert
AU  - Milovanović, Stoja
AU  - Frerich, Sulamith
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5041
AB  - Thermal properties of extrusion and injection grade polylactic acid (PLA) were analysed using high pressure differential scanning calorimetry (HP-DSC) under CO2 pressures of up to 50 MPa. The greatest depression of melting point and degree of crystallinity of the samples occurred at 20–30 MPa (∼97–115 °C). Batch and semi-continuous processes for supercritical foaming and impregnation of PLA with thymol or thyme extract were performed at 30 MPa and 100–110 °C to prevent thymol degradation, decrease heating requirements and ease polymer processing. At these conditions, PLA foams containing 5.6% or 1.1% of thymol and 0.7% of thyme extract were obtained using static or dynamic batch impregnation and semi-continuous extraction-impregnation process for 7 h, respectively. DSC and HP-DSC analyses revealed more pronounced effect of scCO2 plasticizing than foaming on PLA crystallinity. Neat and impregnated PLA foams with pores size of 15-200 μm have potential for food packaging, biomedical and insulation applications.
PB  - Elsevier B.V.
T2  - Journal of Supercritical Fluids
T1  - Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design
EP  - 80
SP  - 71
VL  - 144
DO  - 10.1016/j.supflu.2018.10.008
ER  - 

@article{
author = "Kuska, Robert and Milovanović, Stoja and Frerich, Sulamith and Ivanović, Jasna",
year = "2019",
abstract = "Thermal properties of extrusion and injection grade polylactic acid (PLA) were analysed using high pressure differential scanning calorimetry (HP-DSC) under CO2 pressures of up to 50 MPa. The greatest depression of melting point and degree of crystallinity of the samples occurred at 20–30 MPa (∼97–115 °C). Batch and semi-continuous processes for supercritical foaming and impregnation of PLA with thymol or thyme extract were performed at 30 MPa and 100–110 °C to prevent thymol degradation, decrease heating requirements and ease polymer processing. At these conditions, PLA foams containing 5.6% or 1.1% of thymol and 0.7% of thyme extract were obtained using static or dynamic batch impregnation and semi-continuous extraction-impregnation process for 7 h, respectively. DSC and HP-DSC analyses revealed more pronounced effect of scCO2 plasticizing than foaming on PLA crystallinity. Neat and impregnated PLA foams with pores size of 15-200 μm have potential for food packaging, biomedical and insulation applications.",
publisher = "Elsevier B.V.",
journal = "Journal of Supercritical Fluids",
title = "Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design",
pages = "80-71",
volume = "144",
doi = "10.1016/j.supflu.2018.10.008"
}

Kuska, R., Milovanović, S., Frerich, S.,& Ivanović, J.. (2019). Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design. in Journal of Supercritical Fluids
Elsevier B.V.., 144, 71-80.
https://doi.org/10.1016/j.supflu.2018.10.008

Kuska R, Milovanović S, Frerich S, Ivanović J. Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design. in Journal of Supercritical Fluids. 2019;144:71-80.
doi:10.1016/j.supflu.2018.10.008 .

Kuska, Robert, Milovanović, Stoja, Frerich, Sulamith, Ivanović, Jasna, "Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design" in Journal of Supercritical Fluids, 144 (2019):71-80,
https://doi.org/10.1016/j.supflu.2018.10.008 . .

TY  - JOUR
AU  - Kuska, Robert
AU  - Milovanović, Stoja
AU  - Frerich, Sulamith
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4328
AB  - Thermal properties of extrusion and injection grade polylactic acid (PLA) were analysed using high pressure differential scanning calorimetry (HP-DSC) under CO2 pressures of up to 50 MPa. The greatest depression of melting point and degree of crystallinity of the samples occurred at 20-30 MPa (similar to 97-115 degrees C). Batch and semi continuous processes for supercritical foaming and impregnation of PLA with thymol or thyme extract were performed at 30 MPa and 100-110 degrees C to prevent thymol degradation, decrease heating requirements and ease polymer processing. At these conditions, PLA foams containing 5.6% or 1.1% of thymol and 0.7% of thyme extract were obtained using static or dynamic batch impregnation and semi-continuous extraction-impregnation process for 7 h, respectively. DSC and HP-DSC analyses revealed more pronounced effect of scCO(2) plasticizing than foaming on PLA crystallinity. Neat and impregnated PLA foams with pores size of 15-200 pm have potential for food packaging, biomedical and insulation applications.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design
EP  - 80
SP  - 71
VL  - 144
DO  - 10.1016/j.supflu.2018.10.008
ER  - 

@article{
author = "Kuska, Robert and Milovanović, Stoja and Frerich, Sulamith and Ivanović, Jasna",
year = "2019",
abstract = "Thermal properties of extrusion and injection grade polylactic acid (PLA) were analysed using high pressure differential scanning calorimetry (HP-DSC) under CO2 pressures of up to 50 MPa. The greatest depression of melting point and degree of crystallinity of the samples occurred at 20-30 MPa (similar to 97-115 degrees C). Batch and semi continuous processes for supercritical foaming and impregnation of PLA with thymol or thyme extract were performed at 30 MPa and 100-110 degrees C to prevent thymol degradation, decrease heating requirements and ease polymer processing. At these conditions, PLA foams containing 5.6% or 1.1% of thymol and 0.7% of thyme extract were obtained using static or dynamic batch impregnation and semi-continuous extraction-impregnation process for 7 h, respectively. DSC and HP-DSC analyses revealed more pronounced effect of scCO(2) plasticizing than foaming on PLA crystallinity. Neat and impregnated PLA foams with pores size of 15-200 pm have potential for food packaging, biomedical and insulation applications.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design",
pages = "80-71",
volume = "144",
doi = "10.1016/j.supflu.2018.10.008"
}

Kuska, R., Milovanović, S., Frerich, S.,& Ivanović, J.. (2019). Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 144, 71-80.
https://doi.org/10.1016/j.supflu.2018.10.008

Kuska R, Milovanović S, Frerich S, Ivanović J. Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design. in Journal of Supercritical Fluids. 2019;144:71-80.
doi:10.1016/j.supflu.2018.10.008 .

Kuska, Robert, Milovanović, Stoja, Frerich, Sulamith, Ivanović, Jasna, "Thermal analysis of polylactic acid under high CO2 pressure applied in supercritical impregnation and foaming process design" in Journal of Supercritical Fluids, 144 (2019):71-80,
https://doi.org/10.1016/j.supflu.2018.10.008 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Mraković, Ana
AU  - Kuska, Robert
AU  - Žižović, Irena
AU  - Frerich, Sulamith
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4173
AB  - Amorphous, medical grade poly(D,L-lactic acid) (PLA) and poly(D,L-lactic-co-glycolic acid) (PLGA) were used to develop systems for controlled release of a natural bioactive substance - thymol. Supercritical carbon dioxide (scCO(2)) was successfully used both as an impregnation medium for thymol incorporation into the polymer matrix and a foaming agent in a single-step batch process. Impregnation of samples using low to moderate scCO(2) densities (273 kg/m(3) and 630 kg/m(3)) and short processing times (2 h and 4 h) enabled thymol loading of 0.920/0-6.62% and formation of microcellular foams upon system depressurization. Thymol effect on structural and thermal properties on foamed samples was proven by FTIR and DSC. The effect of CO2 under elevated pressure on the neat polymers was analysed by high pressure DSC. Foaming of polymers with lower molecular weight by CO2 of higher density yielded foams with smaller pores. All tested foams released thymol in a controlled manner in phosphate buffered saline (PBS) at 37 degrees C within 3 to 6 weeks. Higher loading and lower cell density favoured thymol release rate, while its concentration in PBS for the tested period depended on foam interaction with the medium. Representative PLGA foam sample with the highest thymol loading (6.62%) showed controlled thymol release within 72 h in mediums having pH values from 1.1 to 7.4.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science & Engineering C-Materials for Biological Applications
T1  - Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release
EP  - 404
SP  - 394
VL  - 99
DO  - 10.1016/j.msec.2019.01.106
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Mraković, Ana and Kuska, Robert and Žižović, Irena and Frerich, Sulamith and Ivanović, Jasna",
year = "2019",
abstract = "Amorphous, medical grade poly(D,L-lactic acid) (PLA) and poly(D,L-lactic-co-glycolic acid) (PLGA) were used to develop systems for controlled release of a natural bioactive substance - thymol. Supercritical carbon dioxide (scCO(2)) was successfully used both as an impregnation medium for thymol incorporation into the polymer matrix and a foaming agent in a single-step batch process. Impregnation of samples using low to moderate scCO(2) densities (273 kg/m(3) and 630 kg/m(3)) and short processing times (2 h and 4 h) enabled thymol loading of 0.920/0-6.62% and formation of microcellular foams upon system depressurization. Thymol effect on structural and thermal properties on foamed samples was proven by FTIR and DSC. The effect of CO2 under elevated pressure on the neat polymers was analysed by high pressure DSC. Foaming of polymers with lower molecular weight by CO2 of higher density yielded foams with smaller pores. All tested foams released thymol in a controlled manner in phosphate buffered saline (PBS) at 37 degrees C within 3 to 6 weeks. Higher loading and lower cell density favoured thymol release rate, while its concentration in PBS for the tested period depended on foam interaction with the medium. Representative PLGA foam sample with the highest thymol loading (6.62%) showed controlled thymol release within 72 h in mediums having pH values from 1.1 to 7.4.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science & Engineering C-Materials for Biological Applications",
title = "Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release",
pages = "404-394",
volume = "99",
doi = "10.1016/j.msec.2019.01.106"
}

Milovanović, S., Marković, D., Mraković, A., Kuska, R., Žižović, I., Frerich, S.,& Ivanović, J.. (2019). Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release. in Materials Science & Engineering C-Materials for Biological Applications
Elsevier Science Bv, Amsterdam., 99, 394-404.
https://doi.org/10.1016/j.msec.2019.01.106

Milovanović S, Marković D, Mraković A, Kuska R, Žižović I, Frerich S, Ivanović J. Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release. in Materials Science & Engineering C-Materials for Biological Applications. 2019;99:394-404.
doi:10.1016/j.msec.2019.01.106 .

Milovanović, Stoja, Marković, Darka, Mraković, Ana, Kuska, Robert, Žižović, Irena, Frerich, Sulamith, Ivanović, Jasna, "Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release" in Materials Science & Engineering C-Materials for Biological Applications, 99 (2019):394-404,
https://doi.org/10.1016/j.msec.2019.01.106 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4061
AB  - This study explores utilization of biodegradable and biocompatible polymers for controlled release of natural bioactive substance. For that purpose, poly(epsilon-caprolactone) (PCL) beads, cellulose acetate (CA) film, and poly lactic-co-glycolic acid (PLGA) flakes were impregnated with thymol by employing environmentally friendly process of supercritical carbon dioxide (scCO(2)) impregnation. At selected pressure and temperature, prolongation of operating time increased thymol loading. Pure scCO(2) did not affect CA film with average pore diameter of approximately 3 mu m, while it enabled change of PCL beads and PLGA flakes into foams with average pore diameter approximately 175 mu m and 87 mu m, respectively. Additionally to scCO(2), thymol acted as a plasticizer increasing pore size of polymers up to three times. Kinetic of thymol release from selected samples was tested using phosphate buffer saline at 37 degrees C and successfully described with Korsmeyer-Peppas, zero-order, first-order, and Higuchi models. The suggested method of PCL, CA, and PLGA supercritical impregnation led to development of porous, solvent free, added-value materials that release thymol in a controlled manner from 5 h to several days.
PB  - Sage Publications Ltd, London
T2  - Cellular Polymers
T1  - Added-value porous materials for controlled thymol release obtained by supercritical CO2 impregnation process
EP  - 166
IS  - 5-6
SP  - 153
VL  - 38
DO  - 10.1177/0262489319872329
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Ivanović, Jasna",
year = "2019",
abstract = "This study explores utilization of biodegradable and biocompatible polymers for controlled release of natural bioactive substance. For that purpose, poly(epsilon-caprolactone) (PCL) beads, cellulose acetate (CA) film, and poly lactic-co-glycolic acid (PLGA) flakes were impregnated with thymol by employing environmentally friendly process of supercritical carbon dioxide (scCO(2)) impregnation. At selected pressure and temperature, prolongation of operating time increased thymol loading. Pure scCO(2) did not affect CA film with average pore diameter of approximately 3 mu m, while it enabled change of PCL beads and PLGA flakes into foams with average pore diameter approximately 175 mu m and 87 mu m, respectively. Additionally to scCO(2), thymol acted as a plasticizer increasing pore size of polymers up to three times. Kinetic of thymol release from selected samples was tested using phosphate buffer saline at 37 degrees C and successfully described with Korsmeyer-Peppas, zero-order, first-order, and Higuchi models. The suggested method of PCL, CA, and PLGA supercritical impregnation led to development of porous, solvent free, added-value materials that release thymol in a controlled manner from 5 h to several days.",
publisher = "Sage Publications Ltd, London",
journal = "Cellular Polymers",
title = "Added-value porous materials for controlled thymol release obtained by supercritical CO2 impregnation process",
pages = "166-153",
number = "5-6",
volume = "38",
doi = "10.1177/0262489319872329"
}

Milovanović, S., Marković, D.,& Ivanović, J.. (2019). Added-value porous materials for controlled thymol release obtained by supercritical CO2 impregnation process. in Cellular Polymers
Sage Publications Ltd, London., 38(5-6), 153-166.
https://doi.org/10.1177/0262489319872329

Milovanović S, Marković D, Ivanović J. Added-value porous materials for controlled thymol release obtained by supercritical CO2 impregnation process. in Cellular Polymers. 2019;38(5-6):153-166.
doi:10.1177/0262489319872329 .

Milovanović, Stoja, Marković, Darka, Ivanović, Jasna, "Added-value porous materials for controlled thymol release obtained by supercritical CO2 impregnation process" in Cellular Polymers, 38, no. 5-6 (2019):153-166,
https://doi.org/10.1177/0262489319872329 . .

TY  - JOUR
AU  - Radović, Marko N.
AU  - Adamović, Tijana
AU  - Pavlović, Jelena
AU  - Rusmirović, Jelena
AU  - Tadić, Vanja
AU  - Branković, Zorica
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4232
AB  - Supercritical CO2 impregnation process was used for the first time to fabricate biodegradable gelatin-chitosan (G/Ch) films containing dove oil (CO) for potential use in active food packaging. All the impregnations were carried out at moderately low temperature (40 degrees C). Aiming to maximize CO loading in the films with acceptable morphological, structural and thermal properties, CO2 pressure, impregnation time and G:Ch mass ratio were varied. Gelatin fraction in the films of 25-50 wt. %, scCO(2) pressures of 10-20 MPa and impregnation time of 2-6 h impregnation favoured the CO loading. Processing of the film with equal gelatin to chitosan mass ratio (G/Ch(50:50)) at 10 MPa for 2 h yielded sufficiently high loading (56 mg CO/g(film)) without an adverse effect on morphological properties. The G/Ch(50:50) film was therefore chosen for structural and thermal analyses. ATR-FTIR analysis confirmed successful CO incorporation into the G/Ch(50:50) and its interaction with the film. Plasticizing effect of scCO(2) and CO on the film was evidenced by DSC. Incorporation of 56 mg CO/g(film) into the G/Ch(50:50) didn't affect thermal stability of the film. Beside environmental benefits, supercritical impregnation process enables fast fabrication of G/Ch bio-composite films containing CO, thermally stable to 110 degrees C, which is suitable for most of food packaging applications.
PB  - Savez hemijskih inženjera, Beograd
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - Supercritical co2 impregnation of gelatin-chitosan films with clove essential oil and characterization thereof
EP  - 130
IS  - 2
SP  - 119
VL  - 25
DO  - 10.2298/CICEQ180323025R
ER  - 

@article{
author = "Radović, Marko N. and Adamović, Tijana and Pavlović, Jelena and Rusmirović, Jelena and Tadić, Vanja and Branković, Zorica and Ivanović, Jasna",
year = "2019",
abstract = "Supercritical CO2 impregnation process was used for the first time to fabricate biodegradable gelatin-chitosan (G/Ch) films containing dove oil (CO) for potential use in active food packaging. All the impregnations were carried out at moderately low temperature (40 degrees C). Aiming to maximize CO loading in the films with acceptable morphological, structural and thermal properties, CO2 pressure, impregnation time and G:Ch mass ratio were varied. Gelatin fraction in the films of 25-50 wt. %, scCO(2) pressures of 10-20 MPa and impregnation time of 2-6 h impregnation favoured the CO loading. Processing of the film with equal gelatin to chitosan mass ratio (G/Ch(50:50)) at 10 MPa for 2 h yielded sufficiently high loading (56 mg CO/g(film)) without an adverse effect on morphological properties. The G/Ch(50:50) film was therefore chosen for structural and thermal analyses. ATR-FTIR analysis confirmed successful CO incorporation into the G/Ch(50:50) and its interaction with the film. Plasticizing effect of scCO(2) and CO on the film was evidenced by DSC. Incorporation of 56 mg CO/g(film) into the G/Ch(50:50) didn't affect thermal stability of the film. Beside environmental benefits, supercritical impregnation process enables fast fabrication of G/Ch bio-composite films containing CO, thermally stable to 110 degrees C, which is suitable for most of food packaging applications.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "Supercritical co2 impregnation of gelatin-chitosan films with clove essential oil and characterization thereof",
pages = "130-119",
number = "2",
volume = "25",
doi = "10.2298/CICEQ180323025R"
}

Radović, M. N., Adamović, T., Pavlović, J., Rusmirović, J., Tadić, V., Branković, Z.,& Ivanović, J.. (2019). Supercritical co2 impregnation of gelatin-chitosan films with clove essential oil and characterization thereof. in Chemical Industry & Chemical Engineering Quarterly
Savez hemijskih inženjera, Beograd., 25(2), 119-130.
https://doi.org/10.2298/CICEQ180323025R

Radović MN, Adamović T, Pavlović J, Rusmirović J, Tadić V, Branković Z, Ivanović J. Supercritical co2 impregnation of gelatin-chitosan films with clove essential oil and characterization thereof. in Chemical Industry & Chemical Engineering Quarterly. 2019;25(2):119-130.
doi:10.2298/CICEQ180323025R .

Radović, Marko N., Adamović, Tijana, Pavlović, Jelena, Rusmirović, Jelena, Tadić, Vanja, Branković, Zorica, Ivanović, Jasna, "Supercritical co2 impregnation of gelatin-chitosan films with clove essential oil and characterization thereof" in Chemical Industry & Chemical Engineering Quarterly, 25, no. 2 (2019):119-130,
https://doi.org/10.2298/CICEQ180323025R . .

TY  - JOUR
AU  - Đukić-Vuković, Aleksandra
AU  - Mladenović, Dragana
AU  - Ivanović, Jasna
AU  - Pejin, Jelena
AU  - Mojović, Ljiljana
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4253
AB  - Lactic acid (LA) is a platform chemical which can be produced biotechnologically on agricultural residues, wastes and by-products and further used for production of biodegradable, biocompatible LA polymers. These polymers are mostly used for high-end applications but they have potential for much wider application with decrease in production costs. Available technologies and strategies are reviewed in order to point out the issues, challenges and solutions relevant to increase sustainability and competitiveness of LA production on agricultural residues and wastes. Data on chemical composition, regional and seasonal availability of agricultural residues, wastes and by-products are lacking to provide predictable and effective combining for LA production. Precision agriculture, remote sensing and integration with data on chemical composition can help in better planning and more adequate exploitation of available sources in future. Novel pretreatments for the most abundant lignocellulosic feedstocks, which allow utilization of carbohydrates in LA production and side streams like lignin in other biorefineries are needed. Integration of pretreatment, hydrolysis and fermentation under non-sterile conditions or open fermentation mode should enable easier scale up and decrease energy consumption and costs without sacrificing LA purity. Capital investments in improvement of the available technologies are high. Support from policy makers stimulating production of LA polymers from second and third generation feedstocks will help in research, development and faster adoption on larger scale. For production of LA polymers with tailored properties, it is essential to choose the most productive method for LA production and separation from these complex substrates. The shift in research interest from LA polymerization towards "green" processing of LA polymers products is occurring and that will be the additional driving force for the field in future.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Renewable & Sustainable Energy Reviews
T1  - Towards sustainability of lactic acid and poly-lactic acid polymers production
EP  - 252
SP  - 238
VL  - 108
DO  - 10.1016/j.rser.2019.03.050
ER  - 

@article{
author = "Đukić-Vuković, Aleksandra and Mladenović, Dragana and Ivanović, Jasna and Pejin, Jelena and Mojović, Ljiljana",
year = "2019",
abstract = "Lactic acid (LA) is a platform chemical which can be produced biotechnologically on agricultural residues, wastes and by-products and further used for production of biodegradable, biocompatible LA polymers. These polymers are mostly used for high-end applications but they have potential for much wider application with decrease in production costs. Available technologies and strategies are reviewed in order to point out the issues, challenges and solutions relevant to increase sustainability and competitiveness of LA production on agricultural residues and wastes. Data on chemical composition, regional and seasonal availability of agricultural residues, wastes and by-products are lacking to provide predictable and effective combining for LA production. Precision agriculture, remote sensing and integration with data on chemical composition can help in better planning and more adequate exploitation of available sources in future. Novel pretreatments for the most abundant lignocellulosic feedstocks, which allow utilization of carbohydrates in LA production and side streams like lignin in other biorefineries are needed. Integration of pretreatment, hydrolysis and fermentation under non-sterile conditions or open fermentation mode should enable easier scale up and decrease energy consumption and costs without sacrificing LA purity. Capital investments in improvement of the available technologies are high. Support from policy makers stimulating production of LA polymers from second and third generation feedstocks will help in research, development and faster adoption on larger scale. For production of LA polymers with tailored properties, it is essential to choose the most productive method for LA production and separation from these complex substrates. The shift in research interest from LA polymerization towards "green" processing of LA polymers products is occurring and that will be the additional driving force for the field in future.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Renewable & Sustainable Energy Reviews",
title = "Towards sustainability of lactic acid and poly-lactic acid polymers production",
pages = "252-238",
volume = "108",
doi = "10.1016/j.rser.2019.03.050"
}

Đukić-Vuković, A., Mladenović, D., Ivanović, J., Pejin, J.,& Mojović, L.. (2019). Towards sustainability of lactic acid and poly-lactic acid polymers production. in Renewable & Sustainable Energy Reviews
Pergamon-Elsevier Science Ltd, Oxford., 108, 238-252.
https://doi.org/10.1016/j.rser.2019.03.050

Đukić-Vuković A, Mladenović D, Ivanović J, Pejin J, Mojović L. Towards sustainability of lactic acid and poly-lactic acid polymers production. in Renewable & Sustainable Energy Reviews. 2019;108:238-252.
doi:10.1016/j.rser.2019.03.050 .

Đukić-Vuković, Aleksandra, Mladenović, Dragana, Ivanović, Jasna, Pejin, Jelena, Mojović, Ljiljana, "Towards sustainability of lactic acid and poly-lactic acid polymers production" in Renewable & Sustainable Energy Reviews, 108 (2019):238-252,
https://doi.org/10.1016/j.rser.2019.03.050 . .

TY  - JOUR
AU  - Terzić, Ivan
AU  - Ivanović, Jasna
AU  - Žižović, Irena
AU  - Lučić-Škorić, Marija
AU  - Milosavljević, Nedeljko
AU  - Milašinović, Nikola
AU  - Kalagasidis Krušić, Melina
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3946
AB  - Supercritical carbon dioxide (scCO(2)) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO(2) to obtain xero- and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO(2) drying at 11 MPa and 45 degrees C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO(2) at 10 MPa and 35 degrees C. In vitro studies of swelling in PBS at 37 degrees C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG. SCI., 58:2192-2199, 2018.
PB  - Wiley, Hoboken
T2  - Polymer Engineering and Science
T1  - A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol
EP  - 2199
IS  - 12
SP  - 2192
VL  - 58
DO  - 10.1002/pen.24834
ER  - 

@article{
author = "Terzić, Ivan and Ivanović, Jasna and Žižović, Irena and Lučić-Škorić, Marija and Milosavljević, Nedeljko and Milašinović, Nikola and Kalagasidis Krušić, Melina",
year = "2018",
abstract = "Supercritical carbon dioxide (scCO(2)) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO(2) to obtain xero- and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO(2) drying at 11 MPa and 45 degrees C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO(2) at 10 MPa and 35 degrees C. In vitro studies of swelling in PBS at 37 degrees C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG. SCI., 58:2192-2199, 2018.",
publisher = "Wiley, Hoboken",
journal = "Polymer Engineering and Science",
title = "A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol",
pages = "2199-2192",
number = "12",
volume = "58",
doi = "10.1002/pen.24834"
}

Terzić, I., Ivanović, J., Žižović, I., Lučić-Škorić, M., Milosavljević, N., Milašinović, N.,& Kalagasidis Krušić, M.. (2018). A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol. in Polymer Engineering and Science
Wiley, Hoboken., 58(12), 2192-2199.
https://doi.org/10.1002/pen.24834

Terzić I, Ivanović J, Žižović I, Lučić-Škorić M, Milosavljević N, Milašinović N, Kalagasidis Krušić M. A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol. in Polymer Engineering and Science. 2018;58(12):2192-2199.
doi:10.1002/pen.24834 .

Terzić, Ivan, Ivanović, Jasna, Žižović, Irena, Lučić-Škorić, Marija, Milosavljević, Nedeljko, Milašinović, Nikola, Kalagasidis Krušić, Melina, "A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol" in Polymer Engineering and Science, 58, no. 12 (2018):2192-2199,
https://doi.org/10.1002/pen.24834 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Hollermann, Gesa
AU  - Errenst, Cornelia
AU  - Pajnik, Jelena
AU  - Frerich, Sulamith
AU  - Kroll, Stephen
AU  - Rezwan, Kurosch
AU  - Ivanović, Jasna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4037
AB  - Biodegradable polymers with antibacterial properties are highly desirable materials for active food packaging applications. Thymol, a dietary monoterpene phenol with a strong antibacterial activity is abundant in plants belonging to the genus Thymus. This study presents two approaches for supercritical CO2 impregnation of poly (lactic acid)(PLA)/poly(epsilon-caprolactone)(PCL) blended films to induce antibacterial properties of the material: (i) a batch impregnation process for loading pure thymol, and (ii) an integrated supercritical extraction-impregnation process for isolation of thyme extract and its incorporation into the films, operated in both batch or semi-continuous modes with supercritical solution circulation. The PCL content in films, impregnation time and CO2 flow regime were varied to maximize loading of the films with thymol or thyme extract with preserving films' structure and thermal stability. Representative film samples impregnated with thymol and thyme extract were tested against Gram ( - ) (Escherichia col) and Gram( + ) (Bacillus subtilis) model strains, by measuring their metabolic activity and re-cultivation after exposure to the films. The film containing thymol (35.8 wt%) showed a strong antibacterial activity leading to a total reduction of bacterial cell viability. Proposed processes enable fast, controlled and organic solvent-free fabrication of the PLA/PCL films containing natural antibacterial substances at moderately low temperature, with a compact structure and a good thermal stability, for potential use as active food packaging materials.
PB  - Elsevier Science Bv, Amsterdam
T2  - Food Research International
T1  - Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging
EP  - 495
SP  - 486
VL  - 107
DO  - 10.1016/j.foodres.2018.02.065
ER  - 

@article{
author = "Milovanović, Stoja and Hollermann, Gesa and Errenst, Cornelia and Pajnik, Jelena and Frerich, Sulamith and Kroll, Stephen and Rezwan, Kurosch and Ivanović, Jasna",
year = "2018",
abstract = "Biodegradable polymers with antibacterial properties are highly desirable materials for active food packaging applications. Thymol, a dietary monoterpene phenol with a strong antibacterial activity is abundant in plants belonging to the genus Thymus. This study presents two approaches for supercritical CO2 impregnation of poly (lactic acid)(PLA)/poly(epsilon-caprolactone)(PCL) blended films to induce antibacterial properties of the material: (i) a batch impregnation process for loading pure thymol, and (ii) an integrated supercritical extraction-impregnation process for isolation of thyme extract and its incorporation into the films, operated in both batch or semi-continuous modes with supercritical solution circulation. The PCL content in films, impregnation time and CO2 flow regime were varied to maximize loading of the films with thymol or thyme extract with preserving films' structure and thermal stability. Representative film samples impregnated with thymol and thyme extract were tested against Gram ( - ) (Escherichia col) and Gram( + ) (Bacillus subtilis) model strains, by measuring their metabolic activity and re-cultivation after exposure to the films. The film containing thymol (35.8 wt%) showed a strong antibacterial activity leading to a total reduction of bacterial cell viability. Proposed processes enable fast, controlled and organic solvent-free fabrication of the PLA/PCL films containing natural antibacterial substances at moderately low temperature, with a compact structure and a good thermal stability, for potential use as active food packaging materials.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Food Research International",
title = "Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging",
pages = "495-486",
volume = "107",
doi = "10.1016/j.foodres.2018.02.065"
}

Milovanović, S., Hollermann, G., Errenst, C., Pajnik, J., Frerich, S., Kroll, S., Rezwan, K.,& Ivanović, J.. (2018). Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging. in Food Research International
Elsevier Science Bv, Amsterdam., 107, 486-495.
https://doi.org/10.1016/j.foodres.2018.02.065

Milovanović S, Hollermann G, Errenst C, Pajnik J, Frerich S, Kroll S, Rezwan K, Ivanović J. Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging. in Food Research International. 2018;107:486-495.
doi:10.1016/j.foodres.2018.02.065 .

Milovanović, Stoja, Hollermann, Gesa, Errenst, Cornelia, Pajnik, Jelena, Frerich, Sulamith, Kroll, Stephen, Rezwan, Kurosch, Ivanović, Jasna, "Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging" in Food Research International, 107 (2018):486-495,
https://doi.org/10.1016/j.foodres.2018.02.065 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Tadić, Vanja
AU  - Ivanović, Jasna
AU  - Radmanović, Tanja
AU  - Milovanović, Stoja
AU  - Stanković, Milica
AU  - Žižović, Irena
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3867
AB  - Supercritical CO2 extraction of Helichrysum italicum and impregnation of starch xerogels with the extract by using an integrated scCO(2) extraction and impregnation process were performed at 350 bar and 40 degrees C in order to produce biomaterials for possible oral intake of the extract. Xerogels produced by air-drying of acetogels and alcogels were used as carriers in the supercritical impregnation process. The effect of ethanol as a co-solvent, contact time, plant material/carrier mass ratio and xerogel preparation on the impregnation loading was studied. The highest impregnation loading (1.261 +/- 0.22%) was achieved after 5 h impregnation of the xerogel obtained from alcogel using pure scCO(2) and plant material/carrier mass ratio of 10. Chemical analysis of the extracts showed that the addition of ethanol as co-solvent had a positive effect on scCO(2) selectivity to terpene fraction and total flavonoids, while it lowered the total phenolic content. Despite the difference in chemical composition, both extracts expressed similar antioxidant activity according to the DPPH and FRAP methods. The integrated process was shown to be a feasible method for isolation and incorporation of bioactive components of H italicum into starch xerogels.
PB  - Savez hemijskih inženjera, Beograd
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel
EP  - 200
IS  - 2
SP  - 191
VL  - 24
DO  - 10.2298/CICEQ170223031M
ER  - 

@article{
author = "Maksimović, Svetolik and Tadić, Vanja and Ivanović, Jasna and Radmanović, Tanja and Milovanović, Stoja and Stanković, Milica and Žižović, Irena",
year = "2018",
abstract = "Supercritical CO2 extraction of Helichrysum italicum and impregnation of starch xerogels with the extract by using an integrated scCO(2) extraction and impregnation process were performed at 350 bar and 40 degrees C in order to produce biomaterials for possible oral intake of the extract. Xerogels produced by air-drying of acetogels and alcogels were used as carriers in the supercritical impregnation process. The effect of ethanol as a co-solvent, contact time, plant material/carrier mass ratio and xerogel preparation on the impregnation loading was studied. The highest impregnation loading (1.261 +/- 0.22%) was achieved after 5 h impregnation of the xerogel obtained from alcogel using pure scCO(2) and plant material/carrier mass ratio of 10. Chemical analysis of the extracts showed that the addition of ethanol as co-solvent had a positive effect on scCO(2) selectivity to terpene fraction and total flavonoids, while it lowered the total phenolic content. Despite the difference in chemical composition, both extracts expressed similar antioxidant activity according to the DPPH and FRAP methods. The integrated process was shown to be a feasible method for isolation and incorporation of bioactive components of H italicum into starch xerogels.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel",
pages = "200-191",
number = "2",
volume = "24",
doi = "10.2298/CICEQ170223031M"
}

Maksimović, S., Tadić, V., Ivanović, J., Radmanović, T., Milovanović, S., Stanković, M.,& Žižović, I.. (2018). Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel. in Chemical Industry & Chemical Engineering Quarterly
Savez hemijskih inženjera, Beograd., 24(2), 191-200.
https://doi.org/10.2298/CICEQ170223031M

Maksimović S, Tadić V, Ivanović J, Radmanović T, Milovanović S, Stanković M, Žižović I. Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel. in Chemical Industry & Chemical Engineering Quarterly. 2018;24(2):191-200.
doi:10.2298/CICEQ170223031M .

Maksimović, Svetolik, Tadić, Vanja, Ivanović, Jasna, Radmanović, Tanja, Milovanović, Stoja, Stanković, Milica, Žižović, Irena, "Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel" in Chemical Industry & Chemical Engineering Quarterly, 24, no. 2 (2018):191-200,
https://doi.org/10.2298/CICEQ170223031M . .

TY  - CHAP
AU  - Milovanović, Stoja
AU  - Radetić, Maja
AU  - Misić, D.
AU  - Ašanin, Jelena
AU  - Leontijević, V.
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3496
AB  - The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed.
T2  - Cotton Fibres: Characteristics, Uses and Performance
T1  - High pressure modified cotton in wound dressing applications
EP  - 205
SP  - 177
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1463
ER  - 

@inbook{
author = "Milovanović, Stoja and Radetić, Maja and Misić, D. and Ašanin, Jelena and Leontijević, V. and Ivanović, Jasna and Žižović, Irena",
year = "2017",
abstract = "The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed.",
journal = "Cotton Fibres: Characteristics, Uses and Performance",
booktitle = "High pressure modified cotton in wound dressing applications",
pages = "205-177",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1463"
}

Milovanović, S., Radetić, M., Misić, D., Ašanin, J., Leontijević, V., Ivanović, J.,& Žižović, I.. (2017). High pressure modified cotton in wound dressing applications. in Cotton Fibres: Characteristics, Uses and Performance, 177-205.
https://hdl.handle.net/21.15107/rcub_veterinar_1463

Milovanović S, Radetić M, Misić D, Ašanin J, Leontijević V, Ivanović J, Žižović I. High pressure modified cotton in wound dressing applications. in Cotton Fibres: Characteristics, Uses and Performance. 2017;:177-205.
https://hdl.handle.net/21.15107/rcub_veterinar_1463 .

Milovanović, Stoja, Radetić, Maja, Misić, D., Ašanin, Jelena, Leontijević, V., Ivanović, Jasna, Žižović, Irena, "High pressure modified cotton in wound dressing applications" in Cotton Fibres: Characteristics, Uses and Performance (2017):177-205,
https://hdl.handle.net/21.15107/rcub_veterinar_1463 .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Adamović, Tijana
AU  - Aksentijević, Ksenija
AU  - Mišić, Dušan
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3571
AB  - Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 degrees C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.
PB  - Hindawi Ltd, London
T2  - International Journal of Polymer Science
T1  - Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation
VL  - 2017
DO  - 10.1155/2017/8762649
ER  - 

@article{
author = "Milovanović, Stoja and Adamović, Tijana and Aksentijević, Ksenija and Mišić, Dušan and Ivanović, Jasna and Žižović, Irena",
year = "2017",
abstract = "Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 degrees C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.",
publisher = "Hindawi Ltd, London",
journal = "International Journal of Polymer Science",
title = "Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation",
volume = "2017",
doi = "10.1155/2017/8762649"
}

Milovanović, S., Adamović, T., Aksentijević, K., Mišić, D., Ivanović, J.,& Žižović, I.. (2017). Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation. in International Journal of Polymer Science
Hindawi Ltd, London., 2017.
https://doi.org/10.1155/2017/8762649

Milovanović S, Adamović T, Aksentijević K, Mišić D, Ivanović J, Žižović I. Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation. in International Journal of Polymer Science. 2017;2017.
doi:10.1155/2017/8762649 .

Milovanović, Stoja, Adamović, Tijana, Aksentijević, Ksenija, Mišić, Dušan, Ivanović, Jasna, Žižović, Irena, "Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation" in International Journal of Polymer Science, 2017 (2017),
https://doi.org/10.1155/2017/8762649 . .

TY  - JOUR
AU  - Rusmirović, Jelena
AU  - Ivanović, Jasna
AU  - Pavlović, Vladimir B.
AU  - Rakić, Vesna M.
AU  - Rančić, Milica
AU  - Đokić, Veljko
AU  - Marinković, Aleksandar
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3741
AB  - The influence of modification and vacuum/supercritical CO2 (scCO(2)) drying methods on the surface properties, morphology and thermal stability of cellulose nanocrystals (NC) was presented in this study. Introduction of reactive vinyl groups on NC surface was performed by either direct esterification with oleic acid, linseed or sunflower oil fatty acids; or by amidation of maleic acid/ethylene diamine with methyl ester of fatty acid. Obtained modified NC (m-NC) were characterized using MR and Raman spectroscopy; and by determination of acid, iodine and ester values. Structural analysis of m-NC showed varieties of forms, from spongy to nanostructural non-uniform layered morphology with observable agglomeration, which confirmed morphology dependence on modification/processing methods Thermogravimetry-MS spectrometry showed different thermal stability and degradation pathways of NC/m-NC. Incorporation of 1 wt% of reactive m-NC in unsaturated polyester lead to high performance nanocomposites and contributed to increase of stress at break in the range from 76 to 93%.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Novel modified nanocellulose applicable as reinforcement in high-performance nanocomposites
EP  - 74
SP  - 64
VL  - 164
DO  - 10.1016/j.carbpol.2017.01.086
ER  - 

@article{
author = "Rusmirović, Jelena and Ivanović, Jasna and Pavlović, Vladimir B. and Rakić, Vesna M. and Rančić, Milica and Đokić, Veljko and Marinković, Aleksandar",
year = "2017",
abstract = "The influence of modification and vacuum/supercritical CO2 (scCO(2)) drying methods on the surface properties, morphology and thermal stability of cellulose nanocrystals (NC) was presented in this study. Introduction of reactive vinyl groups on NC surface was performed by either direct esterification with oleic acid, linseed or sunflower oil fatty acids; or by amidation of maleic acid/ethylene diamine with methyl ester of fatty acid. Obtained modified NC (m-NC) were characterized using MR and Raman spectroscopy; and by determination of acid, iodine and ester values. Structural analysis of m-NC showed varieties of forms, from spongy to nanostructural non-uniform layered morphology with observable agglomeration, which confirmed morphology dependence on modification/processing methods Thermogravimetry-MS spectrometry showed different thermal stability and degradation pathways of NC/m-NC. Incorporation of 1 wt% of reactive m-NC in unsaturated polyester lead to high performance nanocomposites and contributed to increase of stress at break in the range from 76 to 93%.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Novel modified nanocellulose applicable as reinforcement in high-performance nanocomposites",
pages = "74-64",
volume = "164",
doi = "10.1016/j.carbpol.2017.01.086"
}

Rusmirović, J., Ivanović, J., Pavlović, V. B., Rakić, V. M., Rančić, M., Đokić, V.,& Marinković, A.. (2017). Novel modified nanocellulose applicable as reinforcement in high-performance nanocomposites. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 164, 64-74.
https://doi.org/10.1016/j.carbpol.2017.01.086

Rusmirović J, Ivanović J, Pavlović VB, Rakić VM, Rančić M, Đokić V, Marinković A. Novel modified nanocellulose applicable as reinforcement in high-performance nanocomposites. in Carbohydrate Polymers. 2017;164:64-74.
doi:10.1016/j.carbpol.2017.01.086 .

Rusmirović, Jelena, Ivanović, Jasna, Pavlović, Vladimir B., Rakić, Vesna M., Rančić, Milica, Đokić, Veljko, Marinković, Aleksandar, "Novel modified nanocellulose applicable as reinforcement in high-performance nanocomposites" in Carbohydrate Polymers, 164 (2017):64-74,
https://doi.org/10.1016/j.carbpol.2017.01.086 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Kuska, Robert
AU  - Lučić-Škorić, Marija
AU  - Kalagasidis Krušić, Melina
AU  - Frerich, Sulamith
AU  - Žižović, Irena
AU  - Ivanović, Jasna
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3219
AB  - The present work was aimed to study swelling kinetics of polylactic acid (PLA) and its impregnation with thymol in supercritical carbon dioxide (scCO2) medium. The influences of temperature and soaking time on the swelling kinetics and impregnation yield of PLA cylindrical disc and film were investigated. Swelling experiments were performed in a high pressure view cell at 10 MPa and temperatures of 40°C, 60°C and 75°C for 2 to 24 h. On the basis of swelling kinetics, pressure of 10 MPa and temperature of 40°C were chosen for supercritical solvent impregnation (SSI) of the PLA samples during 2 to24 h. The highest swelling extent was observed for the PLA monolith after 24 h treatment with pure scCO2 (7.5%) and scCO2 with thymol (118.3%). It was shown that sufficiently high amount of thymol can be loaded into both PLA monolith and film using SSI after only 2 h (10.0% and 6.6%, respectively). Monolith and film of PLA impregnated with thymol could be suitable for active food packaging and sterile medical disposables.
AB  - Prikazana studija je namenjena ispitivanju kinetike bubrenja polilaktida (PLA) i njegovoj impregnaciji timolom u natkritičnom ugljenik(IV)-oksidu (nkCO2). Praćen je uticaj temperature i operativnog vremena na kinetiku bubrenja i prinos impregnacije PLA cilindričnog diska i filma. Eksperimenti bubrenja su izvedeni u ćeliji za rad pod visokim pritiscima na 10 MPa and 40°C, 60°C i 75°C od 2 h do 24 h. Na osnovu kinetike bubrenja, natkritična impregnacija uzoraka PLA timolom je izvedena na pritisku od 10 MPa i temperaturi od 40°C tokom 2 do 24 h. Najveći stepen bubrenja je imao PLA disk na 10 MPa i 40°C nakon 24 h (7,5%) u sistemu sa čistim nkCO2 i u sistemu sa timolom (118,3%). Pokazano je da se dovoljno visok prinos impregnacije timola može postići nakon 2 h (10,0% za disk i 6,6% za film). PLA u formi diska i filma impregnirani timolom su pogodni materijali za aktivno pakovanje hrane i za sterilni medicinski pribor.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions
T1  - Kinetika bubrenja PLA i njegova impregnacija timolom upotrebom natkritičnog uglenik(IV)-oksida
EP  - 20
IS  - 1
SP  - 16
VL  - 71
DO  - 10.5937/tehnika1601016M
ER  - 

@article{
author = "Milovanović, Stoja and Kuska, Robert and Lučić-Škorić, Marija and Kalagasidis Krušić, Melina and Frerich, Sulamith and Žižović, Irena and Ivanović, Jasna",
year = "2016",
abstract = "The present work was aimed to study swelling kinetics of polylactic acid (PLA) and its impregnation with thymol in supercritical carbon dioxide (scCO2) medium. The influences of temperature and soaking time on the swelling kinetics and impregnation yield of PLA cylindrical disc and film were investigated. Swelling experiments were performed in a high pressure view cell at 10 MPa and temperatures of 40°C, 60°C and 75°C for 2 to 24 h. On the basis of swelling kinetics, pressure of 10 MPa and temperature of 40°C were chosen for supercritical solvent impregnation (SSI) of the PLA samples during 2 to24 h. The highest swelling extent was observed for the PLA monolith after 24 h treatment with pure scCO2 (7.5%) and scCO2 with thymol (118.3%). It was shown that sufficiently high amount of thymol can be loaded into both PLA monolith and film using SSI after only 2 h (10.0% and 6.6%, respectively). Monolith and film of PLA impregnated with thymol could be suitable for active food packaging and sterile medical disposables., Prikazana studija je namenjena ispitivanju kinetike bubrenja polilaktida (PLA) i njegovoj impregnaciji timolom u natkritičnom ugljenik(IV)-oksidu (nkCO2). Praćen je uticaj temperature i operativnog vremena na kinetiku bubrenja i prinos impregnacije PLA cilindričnog diska i filma. Eksperimenti bubrenja su izvedeni u ćeliji za rad pod visokim pritiscima na 10 MPa and 40°C, 60°C i 75°C od 2 h do 24 h. Na osnovu kinetike bubrenja, natkritična impregnacija uzoraka PLA timolom je izvedena na pritisku od 10 MPa i temperaturi od 40°C tokom 2 do 24 h. Najveći stepen bubrenja je imao PLA disk na 10 MPa i 40°C nakon 24 h (7,5%) u sistemu sa čistim nkCO2 i u sistemu sa timolom (118,3%). Pokazano je da se dovoljno visok prinos impregnacije timola može postići nakon 2 h (10,0% za disk i 6,6% za film). PLA u formi diska i filma impregnirani timolom su pogodni materijali za aktivno pakovanje hrane i za sterilni medicinski pribor.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions, Kinetika bubrenja PLA i njegova impregnacija timolom upotrebom natkritičnog uglenik(IV)-oksida",
pages = "20-16",
number = "1",
volume = "71",
doi = "10.5937/tehnika1601016M"
}

Milovanović, S., Kuska, R., Lučić-Škorić, M., Kalagasidis Krušić, M., Frerich, S., Žižović, I.,& Ivanović, J.. (2016). Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 71(1), 16-20.
https://doi.org/10.5937/tehnika1601016M

Milovanović S, Kuska R, Lučić-Škorić M, Kalagasidis Krušić M, Frerich S, Žižović I, Ivanović J. Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions. in Tehnika. 2016;71(1):16-20.
doi:10.5937/tehnika1601016M .

Milovanović, Stoja, Kuska, Robert, Lučić-Škorić, Marija, Kalagasidis Krušić, Melina, Frerich, Sulamith, Žižović, Irena, Ivanović, Jasna, "Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions" in Tehnika, 71, no. 1 (2016):16-20,
https://doi.org/10.5937/tehnika1601016M . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Aksentijević, Ksenija
AU  - Stojanović, Dušica
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3248
AB  - Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure techniques. Effect of thymol content on CA was confirmed by SEM, FTIR and DSC methods. Kinetic of thymol release from CA was tested using simulated gastric and intestinal fluids (hydrochloric acid and phosphate buffer saline). Results were correlated with Korsmeyer-Peppas and Weibull model. Depending on the thymol content and chemical nature of the release medium, the time of thymol release varied from one to three days indicating CA as a promising carrier of thymol with potential uses from medicine to agriculture. The impregnated CA showed antibacterial activity against 23 tested bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) which is particularly important bearing in mind that this strain causes fatal infections in humans and animals.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Application of cellulose acetate for controlled release of thymol
EP  - 353
SP  - 344
VL  - 147
DO  - 10.1016/j.carbpol.2016.03.093
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Aksentijević, Ksenija and Stojanović, Dušica and Ivanović, Jasna and Žižović, Irena",
year = "2016",
abstract = "Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure techniques. Effect of thymol content on CA was confirmed by SEM, FTIR and DSC methods. Kinetic of thymol release from CA was tested using simulated gastric and intestinal fluids (hydrochloric acid and phosphate buffer saline). Results were correlated with Korsmeyer-Peppas and Weibull model. Depending on the thymol content and chemical nature of the release medium, the time of thymol release varied from one to three days indicating CA as a promising carrier of thymol with potential uses from medicine to agriculture. The impregnated CA showed antibacterial activity against 23 tested bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) which is particularly important bearing in mind that this strain causes fatal infections in humans and animals.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Application of cellulose acetate for controlled release of thymol",
pages = "353-344",
volume = "147",
doi = "10.1016/j.carbpol.2016.03.093"
}

Milovanović, S., Marković, D., Aksentijević, K., Stojanović, D., Ivanović, J.,& Žižović, I.. (2016). Application of cellulose acetate for controlled release of thymol. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 147, 344-353.
https://doi.org/10.1016/j.carbpol.2016.03.093

Milovanović S, Marković D, Aksentijević K, Stojanović D, Ivanović J, Žižović I. Application of cellulose acetate for controlled release of thymol. in Carbohydrate Polymers. 2016;147:344-353.
doi:10.1016/j.carbpol.2016.03.093 .

Milovanović, Stoja, Marković, Darka, Aksentijević, Ksenija, Stojanović, Dušica, Ivanović, Jasna, Žižović, Irena, "Application of cellulose acetate for controlled release of thymol" in Carbohydrate Polymers, 147 (2016):344-353,
https://doi.org/10.1016/j.carbpol.2016.03.093 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Milovanović, Stoja
AU  - Žižović, Irena
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3336
AB  - Modification of native starch enables fabrication of a broad spectrum of technologically valuable products for food and non-food applications. Given the increased public concern about food safety and rigorous environmental regulations, a special attention is paid to non-thermal and organic solvent-free treatments of the starch-based materials. Supercritical carbon dioxide (scCO(2)) is considered to be an attractive processing aid for starch modification due to its unique physicochemical properties such as low viscosity, absence of surface tension, high diffusivity, tuneable density and controllable solvent strength, low critical parameters (7.38MPa, 31.1 degrees C), availability, and environmental acceptability. This is the first review on different use of scCO(2) as a processing aid in setting functionality of starch-based materials including scCO(2)-assisted gelatinization, fabrication of porous materials, impregnation, and chemical modification. In these processes, scCO(2) is used as a plasticizer, blowing agent, solvent, medium or anti-solvent to alter structural, and/or physicochemical properties of starch. The advantages of the scCO(2)-assisted processes for starch modification over the corresponding conventional techniques were discussed in detail.
PB  - Wiley-VCH Verlag Gmbh, Weinheim
T2  - Starch-Starke
T1  - Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials
EP  - 833
IS  - 9-10
SP  - 821
VL  - 68
DO  - 10.1002/star.201500194
ER  - 

@article{
author = "Ivanović, Jasna and Milovanović, Stoja and Žižović, Irena",
year = "2016",
abstract = "Modification of native starch enables fabrication of a broad spectrum of technologically valuable products for food and non-food applications. Given the increased public concern about food safety and rigorous environmental regulations, a special attention is paid to non-thermal and organic solvent-free treatments of the starch-based materials. Supercritical carbon dioxide (scCO(2)) is considered to be an attractive processing aid for starch modification due to its unique physicochemical properties such as low viscosity, absence of surface tension, high diffusivity, tuneable density and controllable solvent strength, low critical parameters (7.38MPa, 31.1 degrees C), availability, and environmental acceptability. This is the first review on different use of scCO(2) as a processing aid in setting functionality of starch-based materials including scCO(2)-assisted gelatinization, fabrication of porous materials, impregnation, and chemical modification. In these processes, scCO(2) is used as a plasticizer, blowing agent, solvent, medium or anti-solvent to alter structural, and/or physicochemical properties of starch. The advantages of the scCO(2)-assisted processes for starch modification over the corresponding conventional techniques were discussed in detail.",
publisher = "Wiley-VCH Verlag Gmbh, Weinheim",
journal = "Starch-Starke",
title = "Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials",
pages = "833-821",
number = "9-10",
volume = "68",
doi = "10.1002/star.201500194"
}

Ivanović, J., Milovanović, S.,& Žižović, I.. (2016). Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials. in Starch-Starke
Wiley-VCH Verlag Gmbh, Weinheim., 68(9-10), 821-833.
https://doi.org/10.1002/star.201500194

Ivanović J, Milovanović S, Žižović I. Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials. in Starch-Starke. 2016;68(9-10):821-833.
doi:10.1002/star.201500194 .

Ivanović, Jasna, Milovanović, Stoja, Žižović, Irena, "Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials" in Starch-Starke, 68, no. 9-10 (2016):821-833,
https://doi.org/10.1002/star.201500194 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Knauer, Sandra
AU  - Fanovich, Alejandra
AU  - Milovanović, Stoja
AU  - Stamenić, Marko
AU  - Jaeger, Philip
AU  - Žižović, Irena
AU  - Eggers, Rudolf
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3407
AB  - The potential of supercritical carbon dioxide (scCO(2)) processing of polycaprolactone (Pa) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 degrees C) was analyzed and quantified. The effect of scCO(2) sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 degrees C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size similar to 200-300 mu m), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO(2) solubility (0.25-0.30 g/g) and mass transfer rate (similar to 10(-10) m(2)/s) in the polymer phase as well as its great plasticizing effect (-Delta T-m = 26.4-27.4 degrees C). Higher saturation of the polymer phase with scCO(2) (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO(2) ( gt 5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
EP  - 498
SP  - 486
VL  - 107
DO  - 10.1016/j.supflu.2015.07.001
ER  - 

@article{
author = "Ivanović, Jasna and Knauer, Sandra and Fanovich, Alejandra and Milovanović, Stoja and Stamenić, Marko and Jaeger, Philip and Žižović, Irena and Eggers, Rudolf",
year = "2016",
abstract = "The potential of supercritical carbon dioxide (scCO(2)) processing of polycaprolactone (Pa) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 degrees C) was analyzed and quantified. The effect of scCO(2) sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 degrees C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size similar to 200-300 mu m), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO(2) solubility (0.25-0.30 g/g) and mass transfer rate (similar to 10(-10) m(2)/s) in the polymer phase as well as its great plasticizing effect (-Delta T-m = 26.4-27.4 degrees C). Higher saturation of the polymer phase with scCO(2) (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO(2) ( gt 5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA",
pages = "498-486",
volume = "107",
doi = "10.1016/j.supflu.2015.07.001"
}

Ivanović, J., Knauer, S., Fanovich, A., Milovanović, S., Stamenić, M., Jaeger, P., Žižović, I.,& Eggers, R.. (2016). Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 107, 486-498.
https://doi.org/10.1016/j.supflu.2015.07.001

Ivanović J, Knauer S, Fanovich A, Milovanović S, Stamenić M, Jaeger P, Žižović I, Eggers R. Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA. in Journal of Supercritical Fluids. 2016;107:486-498.
doi:10.1016/j.supflu.2015.07.001 .

Ivanović, Jasna, Knauer, Sandra, Fanovich, Alejandra, Milovanović, Stoja, Stamenić, Marko, Jaeger, Philip, Žižović, Irena, Eggers, Rudolf, "Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA" in Journal of Supercritical Fluids, 107 (2016):486-498,
https://doi.org/10.1016/j.supflu.2015.07.001 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Pantić, Milica M.
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2908
AB  - The impregnation of differently prepared chitosan gels with thymol using supercritical carbon dioxide (scCO2) was studied in order to obtain new materials with added value without the use of organic solvents. The optimum conditions of supercritical impregnation (15 MPa, 35 °C and 24 h) were defined based on previously investigated thymol solubility in scCO2. Cross-linkers formaldehyde and glutardialdehyde were used to prepare chitosan hydrogels. The obtained hydrogels of chitosan were converted in acetogels and then dried with air or by using scCO2 in order to obtain xerogels and aerogels. The best results, in terms of morphology and yield of impregnation with thymol, have been achieved for the aerogel of chitosan (11.30%) which was obtained with cross-linker formaldehyde and dried with scCO2 at 15 MPa and 50 °C.
AB  - U radu je ispitivana impregnacija različito pripremljenih hitozan gelova sa timolom pomoću natkritičnog ugljenik(IV)-oksida (nkCO2) u cilju dobijanja novih materijala sa dodatom vrednošću bez upotrebe organskih rastvarača. Optimalni uslovi natkritične impregnacije (15 MPa, 35 °C i 24 h) su definisani na osnovu prethodno ispitane rastvorljivosti timola u nkCO2. Za pripremu hidrogelova hitozana korišćeni su umreživači formaldehid i glutardialdehid. Dobijeni hidrogelovi hitozana su prevedeni u acetogelove, a potom sušeni na vazduhu ili pomoću nkCO2 kako bi se dobili kserogelovi ili aerogelovi. Najbolji rezultati u pogledu morfologije i prinosa impregancije sa timolom postignuti su za aerogel hitozana (11,30%) koji je dobijen umrežavanjem sa formaldehidom i sušenjem sa nkCO2 na 15 MPa i 50 °C.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Optimization of chitosan gel preparation for supercritical impregnation of thymol
T1  - Uticaj pripreme hitozan gelova na natkritičnu impregnaciju sa timolom
EP  - 396
IS  - 3
SP  - 391
VL  - 70
DO  - 10.5937/tehnika1503391M
ER  - 

@article{
author = "Milovanović, Stoja and Pantić, Milica M. and Ivanović, Jasna and Žižović, Irena",
year = "2015",
abstract = "The impregnation of differently prepared chitosan gels with thymol using supercritical carbon dioxide (scCO2) was studied in order to obtain new materials with added value without the use of organic solvents. The optimum conditions of supercritical impregnation (15 MPa, 35 °C and 24 h) were defined based on previously investigated thymol solubility in scCO2. Cross-linkers formaldehyde and glutardialdehyde were used to prepare chitosan hydrogels. The obtained hydrogels of chitosan were converted in acetogels and then dried with air or by using scCO2 in order to obtain xerogels and aerogels. The best results, in terms of morphology and yield of impregnation with thymol, have been achieved for the aerogel of chitosan (11.30%) which was obtained with cross-linker formaldehyde and dried with scCO2 at 15 MPa and 50 °C., U radu je ispitivana impregnacija različito pripremljenih hitozan gelova sa timolom pomoću natkritičnog ugljenik(IV)-oksida (nkCO2) u cilju dobijanja novih materijala sa dodatom vrednošću bez upotrebe organskih rastvarača. Optimalni uslovi natkritične impregnacije (15 MPa, 35 °C i 24 h) su definisani na osnovu prethodno ispitane rastvorljivosti timola u nkCO2. Za pripremu hidrogelova hitozana korišćeni su umreživači formaldehid i glutardialdehid. Dobijeni hidrogelovi hitozana su prevedeni u acetogelove, a potom sušeni na vazduhu ili pomoću nkCO2 kako bi se dobili kserogelovi ili aerogelovi. Najbolji rezultati u pogledu morfologije i prinosa impregancije sa timolom postignuti su za aerogel hitozana (11,30%) koji je dobijen umrežavanjem sa formaldehidom i sušenjem sa nkCO2 na 15 MPa i 50 °C.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Optimization of chitosan gel preparation for supercritical impregnation of thymol, Uticaj pripreme hitozan gelova na natkritičnu impregnaciju sa timolom",
pages = "396-391",
number = "3",
volume = "70",
doi = "10.5937/tehnika1503391M"
}

Milovanović, S., Pantić, M. M., Ivanović, J.,& Žižović, I.. (2015). Optimization of chitosan gel preparation for supercritical impregnation of thymol. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 70(3), 391-396.
https://doi.org/10.5937/tehnika1503391M

Milovanović S, Pantić MM, Ivanović J, Žižović I. Optimization of chitosan gel preparation for supercritical impregnation of thymol. in Tehnika. 2015;70(3):391-396.
doi:10.5937/tehnika1503391M .

Milovanović, Stoja, Pantić, Milica M., Ivanović, Jasna, Žižović, Irena, "Optimization of chitosan gel preparation for supercritical impregnation of thymol" in Tehnika, 70, no. 3 (2015):391-396,
https://doi.org/10.5937/tehnika1503391M . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Saičić, Snežana
AU  - Milanović-Stevanović, Mirjana
AU  - Petrović, Nada
AU  - Žižović, Irena
AU  - Petrović, Slobodan
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2947
AB  - The study was aimed to investigate potential of supercritical extract of rosemary (RSE) in the long term oxidative stabilization of pork liver pâté (five years). Determination of peroxide value (PV) and thiobarbituric acid (TBA) assay were used to assess and compare lipid deterioration in pâté samples containing the same content of RSE, butylated hydroxyanisole (BHA) and commercial rosemary antioxidant Flavor'Plus (FP).The first evidence of primary oxidation was reported after five years in all the samples except in those containing low concentrations of RSE (200-500 mg/kg) and FP (500 mg/kg). Increasing concentration of the RSE in pâté (1000 mg/kg) resulted in the lower efficiency in preventing primary oxidation of lipids (PV=0.27 meq/kg). The BHA was reported for the lowest efficiency among tested antioxidants (PV=0.26-0.3 meq/kg). The TBA assay showed no evidence of secondary oxidation products in all the samples due to insufficient amount of formed peroxides. General chemical composition of the pâté samples after five years was not significantly different from the initial one. Since RSE is isolated and deodorized using supercritical fluid technology it doesn't contain traces of organic solvents. For that reason, the RSE would provide an added value to commercial liver pâté due to both natural origin and potential bioactive properties.
AB  - Studija je imala za cilj da istraži potencijal superkritičnog ekstrakta ruzmarina (RSE) u dugoročnoj oksidativnoj stabilizaciji jetrene svinjske paštete (pet godina). Određivanje peroksidne vrednosti (PV) i tiobarbiturne kiseline (TBA test) korišćeni su za procenu i poređenje lipidnog pogoršanja u uzorcima paštete koji imaju isti sadržaj RSE, butilovanog hidroksianizola (BHA) i komercijalnog antioksidansa ruzmarina Flavor'Plus (FP). Prvi dokaz primarne oksidacije je zabeležen nakon pet godina u svim uzorcima osim u onim koji sadrže niske koncentracije RSE (200-500 mg/kg) i FP (500 mg/kg). Povećanje koncentracije RSE u pašteti (1000 mg/kg) je rezultovalo u slabijoj efikasnosti u prevenciji primarne oksidacije lipida (PV = 0,27 meq/kg). BHA vrednost utvrđena za najnižu efi kasnost testiranih antioksidanasa (PV = 0,26-0,3 meq/kg). TBA test je pokazao da nema dokaza sekundarne oksidacije proizvoda u svim uzorcima zbog nedovoljne količine formiranih peroksida. Opšti (osnovni) hemijski sastav uzoraka paštete posle pet godina nije se bitno razlikovao od prvobitnog sastava. Budući da je RSE izolovana i dezodorisana korišćenjem tehnologije superkritičnog fluida, ne sadrži tragove organskih rastvarača. Iz tog razloga, RSE bi obezbedio dodatnu vrednost komercijalnoj jetrenoj pašteti, kako zbog prirodnog porekla tako i zbog potencijalnih bioaktivnih svojstava.
PB  - Institut za higijenu i tehnologiju mesa, Beograd
T2  - Tehnologija mesa
T1  - High efficiency of supercritical rosemary extract in long term oxidative stabilization of pork liver pâté
T1  - Visoka efikasnost superkritičnog ekstrakta ruzmarina u dugoročnoj oksidativnoj stabilizaciji svinjske jetrene paštete
EP  - 49
IS  - 1
SP  - 41
VL  - 56
DO  - 10.5937/tehmesa1501041I
ER  - 

@article{
author = "Ivanović, Jasna and Saičić, Snežana and Milanović-Stevanović, Mirjana and Petrović, Nada and Žižović, Irena and Petrović, Slobodan",
year = "2015",
abstract = "The study was aimed to investigate potential of supercritical extract of rosemary (RSE) in the long term oxidative stabilization of pork liver pâté (five years). Determination of peroxide value (PV) and thiobarbituric acid (TBA) assay were used to assess and compare lipid deterioration in pâté samples containing the same content of RSE, butylated hydroxyanisole (BHA) and commercial rosemary antioxidant Flavor'Plus (FP).The first evidence of primary oxidation was reported after five years in all the samples except in those containing low concentrations of RSE (200-500 mg/kg) and FP (500 mg/kg). Increasing concentration of the RSE in pâté (1000 mg/kg) resulted in the lower efficiency in preventing primary oxidation of lipids (PV=0.27 meq/kg). The BHA was reported for the lowest efficiency among tested antioxidants (PV=0.26-0.3 meq/kg). The TBA assay showed no evidence of secondary oxidation products in all the samples due to insufficient amount of formed peroxides. General chemical composition of the pâté samples after five years was not significantly different from the initial one. Since RSE is isolated and deodorized using supercritical fluid technology it doesn't contain traces of organic solvents. For that reason, the RSE would provide an added value to commercial liver pâté due to both natural origin and potential bioactive properties., Studija je imala za cilj da istraži potencijal superkritičnog ekstrakta ruzmarina (RSE) u dugoročnoj oksidativnoj stabilizaciji jetrene svinjske paštete (pet godina). Određivanje peroksidne vrednosti (PV) i tiobarbiturne kiseline (TBA test) korišćeni su za procenu i poređenje lipidnog pogoršanja u uzorcima paštete koji imaju isti sadržaj RSE, butilovanog hidroksianizola (BHA) i komercijalnog antioksidansa ruzmarina Flavor'Plus (FP). Prvi dokaz primarne oksidacije je zabeležen nakon pet godina u svim uzorcima osim u onim koji sadrže niske koncentracije RSE (200-500 mg/kg) i FP (500 mg/kg). Povećanje koncentracije RSE u pašteti (1000 mg/kg) je rezultovalo u slabijoj efikasnosti u prevenciji primarne oksidacije lipida (PV = 0,27 meq/kg). BHA vrednost utvrđena za najnižu efi kasnost testiranih antioksidanasa (PV = 0,26-0,3 meq/kg). TBA test je pokazao da nema dokaza sekundarne oksidacije proizvoda u svim uzorcima zbog nedovoljne količine formiranih peroksida. Opšti (osnovni) hemijski sastav uzoraka paštete posle pet godina nije se bitno razlikovao od prvobitnog sastava. Budući da je RSE izolovana i dezodorisana korišćenjem tehnologije superkritičnog fluida, ne sadrži tragove organskih rastvarača. Iz tog razloga, RSE bi obezbedio dodatnu vrednost komercijalnoj jetrenoj pašteti, kako zbog prirodnog porekla tako i zbog potencijalnih bioaktivnih svojstava.",
publisher = "Institut za higijenu i tehnologiju mesa, Beograd",
journal = "Tehnologija mesa",
title = "High efficiency of supercritical rosemary extract in long term oxidative stabilization of pork liver pâté, Visoka efikasnost superkritičnog ekstrakta ruzmarina u dugoročnoj oksidativnoj stabilizaciji svinjske jetrene paštete",
pages = "49-41",
number = "1",
volume = "56",
doi = "10.5937/tehmesa1501041I"
}

Ivanović, J., Saičić, S., Milanović-Stevanović, M., Petrović, N., Žižović, I.,& Petrović, S.. (2015). High efficiency of supercritical rosemary extract in long term oxidative stabilization of pork liver pâté. in Tehnologija mesa
Institut za higijenu i tehnologiju mesa, Beograd., 56(1), 41-49.
https://doi.org/10.5937/tehmesa1501041I

Ivanović J, Saičić S, Milanović-Stevanović M, Petrović N, Žižović I, Petrović S. High efficiency of supercritical rosemary extract in long term oxidative stabilization of pork liver pâté. in Tehnologija mesa. 2015;56(1):41-49.
doi:10.5937/tehmesa1501041I .

Ivanović, Jasna, Saičić, Snežana, Milanović-Stevanović, Mirjana, Petrović, Nada, Žižović, Irena, Petrović, Slobodan, "High efficiency of supercritical rosemary extract in long term oxidative stabilization of pork liver pâté" in Tehnologija mesa, 56, no. 1 (2015):41-49,
https://doi.org/10.5937/tehmesa1501041I . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Janković-Častvan, Ivona
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3011
AB  - In this study, for the first time, the supercritical solvent impregnation (SSI) technique has been used to test the incorporation of thymol into starch gels. Corn and tapioca starch hydrogels prepared at different temperatures (70-100 degrees C) were converted to the acetogels and subsequently dried with supercritical CO2 or air to obtain aero- or xerogels, respectively. Starch xero- and aerogels were impregnated with thymol in a high pressure view cell using supercritical CO2 at 15.5MPa and 35 degrees C during 24h. The influence of the botanical origin of starch, temperature for hydrogels preparation (Tgel-h) and drying method on the gel morphology and thymol impregnation yields was discussed. Determined thymol SSI yields were in the range of 1.15-4.02% for the corn and 0.58-3.63% for the tapioca starch gels. Xerogels had higher thymol loading capacities (1.76-4.02%) than aerogels (0.58-3.31%) at given SSI conditions. Gel morphology and thymol SSI yields were positively affected by the Tgel-h increase. The xerogel obtained from the corn starch hydrogel prepared at 100 degrees C had the largest specific surface area (5.52m(2)/g) and thymol loading capacity (4.02%) at given SSI conditions. These results, along with a simple and low-cost production, indicated the great potential of the corn starch xerogel for commercial use as a carrier in pharmaceuticals and nutraceuticals.
PB  - Wiley-VCH Verlag Gmbh, Weinheim
T2  - Starch-Starke
T1  - Effect of starch xero- and aerogels preparation on the supercritical CO2 impregnation of thymol
EP  - 182
IS  - 1-2
SP  - 174
VL  - 67
DO  - 10.1002/star.201400134
ER  - 

@article{
author = "Milovanović, Stoja and Janković-Častvan, Ivona and Ivanović, Jasna and Žižović, Irena",
year = "2015",
abstract = "In this study, for the first time, the supercritical solvent impregnation (SSI) technique has been used to test the incorporation of thymol into starch gels. Corn and tapioca starch hydrogels prepared at different temperatures (70-100 degrees C) were converted to the acetogels and subsequently dried with supercritical CO2 or air to obtain aero- or xerogels, respectively. Starch xero- and aerogels were impregnated with thymol in a high pressure view cell using supercritical CO2 at 15.5MPa and 35 degrees C during 24h. The influence of the botanical origin of starch, temperature for hydrogels preparation (Tgel-h) and drying method on the gel morphology and thymol impregnation yields was discussed. Determined thymol SSI yields were in the range of 1.15-4.02% for the corn and 0.58-3.63% for the tapioca starch gels. Xerogels had higher thymol loading capacities (1.76-4.02%) than aerogels (0.58-3.31%) at given SSI conditions. Gel morphology and thymol SSI yields were positively affected by the Tgel-h increase. The xerogel obtained from the corn starch hydrogel prepared at 100 degrees C had the largest specific surface area (5.52m(2)/g) and thymol loading capacity (4.02%) at given SSI conditions. These results, along with a simple and low-cost production, indicated the great potential of the corn starch xerogel for commercial use as a carrier in pharmaceuticals and nutraceuticals.",
publisher = "Wiley-VCH Verlag Gmbh, Weinheim",
journal = "Starch-Starke",
title = "Effect of starch xero- and aerogels preparation on the supercritical CO2 impregnation of thymol",
pages = "182-174",
number = "1-2",
volume = "67",
doi = "10.1002/star.201400134"
}

Milovanović, S., Janković-Častvan, I., Ivanović, J.,& Žižović, I.. (2015). Effect of starch xero- and aerogels preparation on the supercritical CO2 impregnation of thymol. in Starch-Starke
Wiley-VCH Verlag Gmbh, Weinheim., 67(1-2), 174-182.
https://doi.org/10.1002/star.201400134

Milovanović S, Janković-Častvan I, Ivanović J, Žižović I. Effect of starch xero- and aerogels preparation on the supercritical CO2 impregnation of thymol. in Starch-Starke. 2015;67(1-2):174-182.
doi:10.1002/star.201400134 .

Milovanović, Stoja, Janković-Častvan, Ivona, Ivanović, Jasna, Žižović, Irena, "Effect of starch xero- and aerogels preparation on the supercritical CO2 impregnation of thymol" in Starch-Starke, 67, no. 1-2 (2015):174-182,
https://doi.org/10.1002/star.201400134 . .