TY  - JOUR
AU  - Espina, Jaime A.
AU  - Cordeiro, Marilia H.
AU  - Milivojević, Milan
AU  - Pajić-Lijaković, Ivana
AU  - Barriga, Elias H.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6662
AB  - Shear stress is essential for normal physiology and malignancy. Common physiological processes - such as blood flow, particle flow in the gut, or contact between migratory cell clusters and their substrate - produce shear stress that can have an impact on the behavior of different tissues. In addition, shear stress has roles in processes of biomedical interest, such as wound healing, cancer and fibrosis induced by soft implants. Thus, understanding how cells react and adapt to shear stress is important. In this Review, we discuss in vivo and in vitro data obtained from vascular and epithelial models; highlight the insights these have afforded regarding the general mechanisms through which cells sense, transduce and respond to shear stress at the cellular levels; and outline how the changes cells experience in response to shear stress impact tissue organization. Finally, we discuss the role of shear stress in collective cell migration, which is only starting to be appreciated. We review our current understanding of the effects of shear stress in the context of embryo development, cancer and fibrosis, and invite the scientific community to further investigate the role of shear stress in these scenarios.
PB  - Company of Biologists Ltd.
T2  - Journal of Cell Science
T1  - Response of cells and tissues to shear stress
IS  - 18
SP  - jcs260985
VL  - 136
DO  - 10.1242/jcs.260985
ER  - 

@article{
author = "Espina, Jaime A. and Cordeiro, Marilia H. and Milivojević, Milan and Pajić-Lijaković, Ivana and Barriga, Elias H.",
year = "2023",
abstract = "Shear stress is essential for normal physiology and malignancy. Common physiological processes - such as blood flow, particle flow in the gut, or contact between migratory cell clusters and their substrate - produce shear stress that can have an impact on the behavior of different tissues. In addition, shear stress has roles in processes of biomedical interest, such as wound healing, cancer and fibrosis induced by soft implants. Thus, understanding how cells react and adapt to shear stress is important. In this Review, we discuss in vivo and in vitro data obtained from vascular and epithelial models; highlight the insights these have afforded regarding the general mechanisms through which cells sense, transduce and respond to shear stress at the cellular levels; and outline how the changes cells experience in response to shear stress impact tissue organization. Finally, we discuss the role of shear stress in collective cell migration, which is only starting to be appreciated. We review our current understanding of the effects of shear stress in the context of embryo development, cancer and fibrosis, and invite the scientific community to further investigate the role of shear stress in these scenarios.",
publisher = "Company of Biologists Ltd.",
journal = "Journal of Cell Science",
title = "Response of cells and tissues to shear stress",
number = "18",
pages = "jcs260985",
volume = "136",
doi = "10.1242/jcs.260985"
}

Espina, J. A., Cordeiro, M. H., Milivojević, M., Pajić-Lijaković, I.,& Barriga, E. H.. (2023). Response of cells and tissues to shear stress. in Journal of Cell Science
Company of Biologists Ltd.., 136(18), jcs260985.
https://doi.org/10.1242/jcs.260985

Espina JA, Cordeiro MH, Milivojević M, Pajić-Lijaković I, Barriga EH. Response of cells and tissues to shear stress. in Journal of Cell Science. 2023;136(18):jcs260985.
doi:10.1242/jcs.260985 .

Espina, Jaime A., Cordeiro, Marilia H., Milivojević, Milan, Pajić-Lijaković, Ivana, Barriga, Elias H., "Response of cells and tissues to shear stress" in Journal of Cell Science, 136, no. 18 (2023):jcs260985,
https://doi.org/10.1242/jcs.260985 . .

TY  - JOUR
AU  - Pajić-Lijaković, Ivana
AU  - Guevorkian, Karine
AU  - Barriga, Elias H.
AU  - Munoz, Jose J.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4829
AB  - This issue gathers exciting multi-disciplinary work relating viscoelasticity and collective cell remodeling within various biological processes such as morphogenesis, tumorigenesis, and wound healing. Viscoelasticity is influenced by energy transfer and dissipation during cell rearrangement at various time and space scales. Cumulative structural changes at a subcellular level have effects on viscoelasticity at a supracellular level. Established configurations of migrating cells and the rate of their change, which significantly regulate viscoelasticity at a supracellular level, have the impact on the cohesiveness inhomogeneity and various mechanical and biochemical processes at a subcellular level. This Research Topic aims to connect the macroscopic viscoelastic parameters with the individual and collective cell response. Consideration of biochemical, biophysical and bio-mechanical aspects responsible for tissue remodeling, intercalation, and migration were discussed on various multicellular systems under in vivo and in vitro conditions. Thus in this Research Topic we aim to provide a state-of-the-art view about the current knowledge related to viscoelasticity caused by collective cell remodeling and adhesive contractile properties, covering a plethora of phenomena such as: 1) single cell response under stretched monolayers modeled with an improved Vertex model, 2) adhesion percolation within a tissue as an important factor which influences its viscoelasticity, 3) the active turbulence caused by collective cell migration accompanied with the generation of mechanical waves, 4) cell jamming state transitions, and 5) viscoelastic response characterization in liver diseases. Alternative techniques to measure and control cell rearrangement under various experimental conditions are also considered, including atomic force microscopy measurements and various elastography techniques. This Research Topic provides an overview of the current understanding of various: biological, biochemical, biophysical and mechanical aspects of cell remodeling. The inter-relation between cell remodeling and tissue viscoelasticity was discussed by emphasizing the relevant rheological parameters, the way of their measurement under in vivo/ in vitro conditions, and the strategy of multi-scale constitutive modeling.
T2  - Frontiers in Physics
T1  - Editorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling
VL  - 9
DO  - 10.3389/fphy.2021.773096
ER  - 

@article{
author = "Pajić-Lijaković, Ivana and Guevorkian, Karine and Barriga, Elias H. and Munoz, Jose J.",
year = "2021",
abstract = "This issue gathers exciting multi-disciplinary work relating viscoelasticity and collective cell remodeling within various biological processes such as morphogenesis, tumorigenesis, and wound healing. Viscoelasticity is influenced by energy transfer and dissipation during cell rearrangement at various time and space scales. Cumulative structural changes at a subcellular level have effects on viscoelasticity at a supracellular level. Established configurations of migrating cells and the rate of their change, which significantly regulate viscoelasticity at a supracellular level, have the impact on the cohesiveness inhomogeneity and various mechanical and biochemical processes at a subcellular level. This Research Topic aims to connect the macroscopic viscoelastic parameters with the individual and collective cell response. Consideration of biochemical, biophysical and bio-mechanical aspects responsible for tissue remodeling, intercalation, and migration were discussed on various multicellular systems under in vivo and in vitro conditions. Thus in this Research Topic we aim to provide a state-of-the-art view about the current knowledge related to viscoelasticity caused by collective cell remodeling and adhesive contractile properties, covering a plethora of phenomena such as: 1) single cell response under stretched monolayers modeled with an improved Vertex model, 2) adhesion percolation within a tissue as an important factor which influences its viscoelasticity, 3) the active turbulence caused by collective cell migration accompanied with the generation of mechanical waves, 4) cell jamming state transitions, and 5) viscoelastic response characterization in liver diseases. Alternative techniques to measure and control cell rearrangement under various experimental conditions are also considered, including atomic force microscopy measurements and various elastography techniques. This Research Topic provides an overview of the current understanding of various: biological, biochemical, biophysical and mechanical aspects of cell remodeling. The inter-relation between cell remodeling and tissue viscoelasticity was discussed by emphasizing the relevant rheological parameters, the way of their measurement under in vivo/ in vitro conditions, and the strategy of multi-scale constitutive modeling.",
journal = "Frontiers in Physics",
title = "Editorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling",
volume = "9",
doi = "10.3389/fphy.2021.773096"
}

Pajić-Lijaković, I., Guevorkian, K., Barriga, E. H.,& Munoz, J. J.. (2021). Editorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling. in Frontiers in Physics, 9.
https://doi.org/10.3389/fphy.2021.773096

Pajić-Lijaković I, Guevorkian K, Barriga EH, Munoz JJ. Editorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling. in Frontiers in Physics. 2021;9.
doi:10.3389/fphy.2021.773096 .

Pajić-Lijaković, Ivana, Guevorkian, Karine, Barriga, Elias H., Munoz, Jose J., "Editorial: Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling" in Frontiers in Physics, 9 (2021),
https://doi.org/10.3389/fphy.2021.773096 . .