Response of cells and tissues to shear stress
Аутори
Espina, Jaime A.Cordeiro, Marilia H.
Milivojević, Milan
Pajić-Lijaković, Ivana
Barriga, Elias H.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Shear stress is essential for normal physiology and malignancy. Common physiological processes - such as blood flow, particle flow in the gut, or contact between migratory cell clusters and their substrate - produce shear stress that can have an impact on the behavior of different tissues. In addition, shear stress has roles in processes of biomedical interest, such as wound healing, cancer and fibrosis induced by soft implants. Thus, understanding how cells react and adapt to shear stress is important. In this Review, we discuss in vivo and in vitro data obtained from vascular and epithelial models; highlight the insights these have afforded regarding the general mechanisms through which cells sense, transduce and respond to shear stress at the cellular levels; and outline how the changes cells experience in response to shear stress impact tissue organization. Finally, we discuss the role of shear stress in collective cell migration, which is only starting to be appreciated. We review... our current understanding of the effects of shear stress in the context of embryo development, cancer and fibrosis, and invite the scientific community to further investigate the role of shear stress in these scenarios.
Кључне речи:
Biomechanics / Cytoskeleton / Fluid shear stress / Shear stressИзвор:
Journal of Cell Science, 2023, 136, 18, jcs260985-Издавач:
- Company of Biologists Ltd.
Финансирање / пројекти:
- European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (grant agreement 950254)
- EMBO installation grant (project number 4765)
- Caixa’ Foundation Junior Leader Incoming Fellowship (94978)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200135 (Универзитет у Београду, Технолошко-металуршки факултет) (RS-MESTD-inst-2020-200135)
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Espina, Jaime A. AU - Cordeiro, Marilia H. AU - Milivojević, Milan AU - Pajić-Lijaković, Ivana AU - Barriga, Elias H. PY - 2023 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6662 AB - Shear stress is essential for normal physiology and malignancy. Common physiological processes - such as blood flow, particle flow in the gut, or contact between migratory cell clusters and their substrate - produce shear stress that can have an impact on the behavior of different tissues. In addition, shear stress has roles in processes of biomedical interest, such as wound healing, cancer and fibrosis induced by soft implants. Thus, understanding how cells react and adapt to shear stress is important. In this Review, we discuss in vivo and in vitro data obtained from vascular and epithelial models; highlight the insights these have afforded regarding the general mechanisms through which cells sense, transduce and respond to shear stress at the cellular levels; and outline how the changes cells experience in response to shear stress impact tissue organization. Finally, we discuss the role of shear stress in collective cell migration, which is only starting to be appreciated. We review our current understanding of the effects of shear stress in the context of embryo development, cancer and fibrosis, and invite the scientific community to further investigate the role of shear stress in these scenarios. PB - Company of Biologists Ltd. T2 - Journal of Cell Science T1 - Response of cells and tissues to shear stress IS - 18 SP - jcs260985 VL - 136 DO - 10.1242/jcs.260985 ER -
@article{ author = "Espina, Jaime A. and Cordeiro, Marilia H. and Milivojević, Milan and Pajić-Lijaković, Ivana and Barriga, Elias H.", year = "2023", abstract = "Shear stress is essential for normal physiology and malignancy. Common physiological processes - such as blood flow, particle flow in the gut, or contact between migratory cell clusters and their substrate - produce shear stress that can have an impact on the behavior of different tissues. In addition, shear stress has roles in processes of biomedical interest, such as wound healing, cancer and fibrosis induced by soft implants. Thus, understanding how cells react and adapt to shear stress is important. In this Review, we discuss in vivo and in vitro data obtained from vascular and epithelial models; highlight the insights these have afforded regarding the general mechanisms through which cells sense, transduce and respond to shear stress at the cellular levels; and outline how the changes cells experience in response to shear stress impact tissue organization. Finally, we discuss the role of shear stress in collective cell migration, which is only starting to be appreciated. We review our current understanding of the effects of shear stress in the context of embryo development, cancer and fibrosis, and invite the scientific community to further investigate the role of shear stress in these scenarios.", publisher = "Company of Biologists Ltd.", journal = "Journal of Cell Science", title = "Response of cells and tissues to shear stress", number = "18", pages = "jcs260985", volume = "136", doi = "10.1242/jcs.260985" }
Espina, J. A., Cordeiro, M. H., Milivojević, M., Pajić-Lijaković, I.,& Barriga, E. H.. (2023). Response of cells and tissues to shear stress. in Journal of Cell Science Company of Biologists Ltd.., 136(18), jcs260985. https://doi.org/10.1242/jcs.260985
Espina JA, Cordeiro MH, Milivojević M, Pajić-Lijaković I, Barriga EH. Response of cells and tissues to shear stress. in Journal of Cell Science. 2023;136(18):jcs260985. doi:10.1242/jcs.260985 .
Espina, Jaime A., Cordeiro, Marilia H., Milivojević, Milan, Pajić-Lijaković, Ivana, Barriga, Elias H., "Response of cells and tissues to shear stress" in Journal of Cell Science, 136, no. 18 (2023):jcs260985, https://doi.org/10.1242/jcs.260985 . .