Belić, Aleksandar

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  • Belić, Aleksandar (2)
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Author's Bibliography

Investigation of electrohydrodynamic calculations

Bošković, Stefan A.; Karač, Aleksandar; Vrhovac, Slobodan B.; Belić, Aleksandar; Bugarski, Branko

(Savez hemijskih inženjera Srbije, 2022)

TY  - JOUR
AU  - Bošković, Stefan A.
AU  - Karač, Aleksandar
AU  - Vrhovac, Slobodan B.
AU  - Belić, Aleksandar
AU  - Bugarski, Branko
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5148
AB  - A perfect dielectric model was incorporated into the OpenFOAM® software and used for investigation and, possibly, improvements of electrohydrodynamic calculations. Two different sets of numerical simulations were analyzed, in which two different fluids were present. The first set was one-dimensional, while in the second, a drop of one fluid was surrounded by the other fluid. It is shown that oscillations and possibly artificial generation of a curl of the electric field strength can be observed at applying certain expressions or calculation strategies, which can be thus abandoned. Usage of dynamic meshes, at least those present in the used software, and of limiters for the gradient of the electric field strength can lead to large numerical errors. It is also shown that usage of certain cell face values could improve the results. An electric Courant number was derived by dimensional analysis, and it could be suggested for future calculations. Conclusions made in this paper are expected to be transferable to other more complicated models.
AB  - Model idealnog dielektrika je uključen u programski paket OpenFOAM® (OpenFOAM Foundation, UK) i korišćen za ispitivanje i moguće poboljšavanje elektrohidrodinamičkih proračuna. Analizirana su dva različita seta numeričkih simulacija, u kojima su bila modelovana dva različita fluida. Prvi set je bio jednodimenzionalan dok je u drugom setu kap jednog fluida bila okružena drugim fluidom. U radu je pokazano da se određeni izrazi ili strategije izračunavanja mogu odbaciti usled pojave oscilacija i mogućeg veštačkog stvaranja rotora jačine električnog polja. Korišćenje pokretnih mreža, barem onih prisutnih u programskom paketu OpenFOAM®, i limitera za gradijent jačine električnog polja mogu dovesti do velikih numeričkih grešaka. Takođe je pokazano da bi korišćenje određenih vrednosti sa površi ćelija moglo poboljšati rezultate. Izraz za električni Kuronov broj je izveden dimenzionom analizom i mogao bi se preporučiti za buduće proračune. Očekuje se da su zaključci iz ovog rada prenosivi na druge, komplikovanije modele.
PB  - Savez hemijskih inženjera Srbije
T2  - Hemijska industrija
T1  - Investigation of electrohydrodynamic calculations
T1  - Ispitivanje elektrohidrodinamičkih proračuna
EP  - 74
IS  - 2
SP  - 65
VL  - 76
DO  - 10.2298/HEMIND211110010B
ER  - 
@article{
author = "Bošković, Stefan A. and Karač, Aleksandar and Vrhovac, Slobodan B. and Belić, Aleksandar and Bugarski, Branko",
year = "2022",
abstract = "A perfect dielectric model was incorporated into the OpenFOAM® software and used for investigation and, possibly, improvements of electrohydrodynamic calculations. Two different sets of numerical simulations were analyzed, in which two different fluids were present. The first set was one-dimensional, while in the second, a drop of one fluid was surrounded by the other fluid. It is shown that oscillations and possibly artificial generation of a curl of the electric field strength can be observed at applying certain expressions or calculation strategies, which can be thus abandoned. Usage of dynamic meshes, at least those present in the used software, and of limiters for the gradient of the electric field strength can lead to large numerical errors. It is also shown that usage of certain cell face values could improve the results. An electric Courant number was derived by dimensional analysis, and it could be suggested for future calculations. Conclusions made in this paper are expected to be transferable to other more complicated models., Model idealnog dielektrika je uključen u programski paket OpenFOAM® (OpenFOAM Foundation, UK) i korišćen za ispitivanje i moguće poboljšavanje elektrohidrodinamičkih proračuna. Analizirana su dva različita seta numeričkih simulacija, u kojima su bila modelovana dva različita fluida. Prvi set je bio jednodimenzionalan dok je u drugom setu kap jednog fluida bila okružena drugim fluidom. U radu je pokazano da se određeni izrazi ili strategije izračunavanja mogu odbaciti usled pojave oscilacija i mogućeg veštačkog stvaranja rotora jačine električnog polja. Korišćenje pokretnih mreža, barem onih prisutnih u programskom paketu OpenFOAM®, i limitera za gradijent jačine električnog polja mogu dovesti do velikih numeričkih grešaka. Takođe je pokazano da bi korišćenje određenih vrednosti sa površi ćelija moglo poboljšati rezultate. Izraz za električni Kuronov broj je izveden dimenzionom analizom i mogao bi se preporučiti za buduće proračune. Očekuje se da su zaključci iz ovog rada prenosivi na druge, komplikovanije modele.",
publisher = "Savez hemijskih inženjera Srbije",
journal = "Hemijska industrija",
title = "Investigation of electrohydrodynamic calculations, Ispitivanje elektrohidrodinamičkih proračuna",
pages = "74-65",
number = "2",
volume = "76",
doi = "10.2298/HEMIND211110010B"
}
Bošković, S. A., Karač, A., Vrhovac, S. B., Belić, A.,& Bugarski, B.. (2022). Investigation of electrohydrodynamic calculations. in Hemijska industrija
Savez hemijskih inženjera Srbije., 76(2), 65-74.
https://doi.org/10.2298/HEMIND211110010B
Bošković SA, Karač A, Vrhovac SB, Belić A, Bugarski B. Investigation of electrohydrodynamic calculations. in Hemijska industrija. 2022;76(2):65-74.
doi:10.2298/HEMIND211110010B .
Bošković, Stefan A., Karač, Aleksandar, Vrhovac, Slobodan B., Belić, Aleksandar, Bugarski, Branko, "Investigation of electrohydrodynamic calculations" in Hemijska industrija, 76, no. 2 (2022):65-74,
https://doi.org/10.2298/HEMIND211110010B . .
1

Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate

Drvenica, Ivana; Bukara, Katarina; Ilić, Vesna Lj.; Mišić, Danijela; Vasić, Borislav; Gajić, Radoš B.; Đorđević, Verica; Veljović, Đorđe; Belić, Aleksandar; Bugarski, Branko

(Wiley, Hoboken, 2016)

TY  - JOUR
AU  - Drvenica, Ivana
AU  - Bukara, Katarina
AU  - Ilić, Vesna Lj.
AU  - Mišić, Danijela
AU  - Vasić, Borislav
AU  - Gajić, Radoš B.
AU  - Đorđević, Verica
AU  - Veljović, Đorđe
AU  - Belić, Aleksandar
AU  - Bugarski, Branko
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3329
AB  - The present study investigated preparation of bovine and porcine erythrocyte membranes from slaughterhouse blood as bio-derived materials for delivery of dexamethasone-sodium phosphate (DexP). The obtained biomembranes, i.e., ghosts were characterized in vitro in terms of morphological properties, loading parameters, and release behavior. For the last two, an UHPLC/-HESI-MS/MS based analytical procedure for absolute drug identification and quantification was developed. The results revealed that loading of DexP into both type of ghosts was directly proportional to the increase of drug concentration in the incubation medium, while incubation at 37 degrees C had statistically significant effect on loaded amount of DexP (P lt 0.05). The encapsulation efficiency was about fivefold higher in porcine compared to bovine ghosts. Insight into ghosts' surface morphology by field emission-scanning electron microscopy and atomic force microscopy confirmed that besides inevitable effects of osmosis, DexP inclusion itself had no observable additional effect on the morphology of the ghosts carriers. DexP release profiles were dependent on erythrocyte ghost type and amount of residual hemoglobin. However, sustained DexP release was achieved and shown over 3 days from porcine ghosts and 5 days from bovine erythrocyte ghosts.
PB  - Wiley, Hoboken
T2  - Biotechnology Progress
T1  - Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate
EP  - 1055
IS  - 4
SP  - 1046
VL  - 32
DO  - 10.1002/btpr.2304
ER  - 
@article{
author = "Drvenica, Ivana and Bukara, Katarina and Ilić, Vesna Lj. and Mišić, Danijela and Vasić, Borislav and Gajić, Radoš B. and Đorđević, Verica and Veljović, Đorđe and Belić, Aleksandar and Bugarski, Branko",
year = "2016",
abstract = "The present study investigated preparation of bovine and porcine erythrocyte membranes from slaughterhouse blood as bio-derived materials for delivery of dexamethasone-sodium phosphate (DexP). The obtained biomembranes, i.e., ghosts were characterized in vitro in terms of morphological properties, loading parameters, and release behavior. For the last two, an UHPLC/-HESI-MS/MS based analytical procedure for absolute drug identification and quantification was developed. The results revealed that loading of DexP into both type of ghosts was directly proportional to the increase of drug concentration in the incubation medium, while incubation at 37 degrees C had statistically significant effect on loaded amount of DexP (P lt 0.05). The encapsulation efficiency was about fivefold higher in porcine compared to bovine ghosts. Insight into ghosts' surface morphology by field emission-scanning electron microscopy and atomic force microscopy confirmed that besides inevitable effects of osmosis, DexP inclusion itself had no observable additional effect on the morphology of the ghosts carriers. DexP release profiles were dependent on erythrocyte ghost type and amount of residual hemoglobin. However, sustained DexP release was achieved and shown over 3 days from porcine ghosts and 5 days from bovine erythrocyte ghosts.",
publisher = "Wiley, Hoboken",
journal = "Biotechnology Progress",
title = "Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate",
pages = "1055-1046",
number = "4",
volume = "32",
doi = "10.1002/btpr.2304"
}
Drvenica, I., Bukara, K., Ilić, V. Lj., Mišić, D., Vasić, B., Gajić, R. B., Đorđević, V., Veljović, Đ., Belić, A.,& Bugarski, B.. (2016). Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate. in Biotechnology Progress
Wiley, Hoboken., 32(4), 1046-1055.
https://doi.org/10.1002/btpr.2304
Drvenica I, Bukara K, Ilić VL, Mišić D, Vasić B, Gajić RB, Đorđević V, Veljović Đ, Belić A, Bugarski B. Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate. in Biotechnology Progress. 2016;32(4):1046-1055.
doi:10.1002/btpr.2304 .
Drvenica, Ivana, Bukara, Katarina, Ilić, Vesna Lj., Mišić, Danijela, Vasić, Borislav, Gajić, Radoš B., Đorđević, Verica, Veljović, Đorđe, Belić, Aleksandar, Bugarski, Branko, "Biomembranes from slaughterhouse blood erythrocytes as prolonged release systems for dexamethasone sodium phosphate" in Biotechnology Progress, 32, no. 4 (2016):1046-1055,
https://doi.org/10.1002/btpr.2304 . .
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