TY  - JOUR
AU  - Lučić Škorić, Marija
AU  - Milovanović, Stoja
AU  - Žižović, Irena
AU  - Ortega-Toro, Rodrigo
AU  - Santagata, Gabriella
AU  - Malinconico, Mario
AU  - Kalagasidis Krušić, Melina
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5243
AB  - The aim of the present study was to investigate starch-based materials, prepared in an environmentally friendly way and from renewable resources, suitable for the development of biodegradable active food packaging. For this purpose, a bioactive compound (thymol) was incorporated into thermoplastic starch (TPS) and a TPS blend with poly (ε-caprolactone) (TPS–PCL) by the supercritical CO2 (scCO2) impregnation process. Impregnation experiments with scCO2 were carried out at a pressure of 30 MPa and temperatures in the range of 40–100 °C during 1 to 20 h. The structural, morphological, and thermal properties of the obtained materials were comprehensively evaluated. Bioactive component release kinetic studies were performed in water at 6 °C and 25 °C. It was shown that the scCO2 impregnation process could be successfully employed for thymol loading into TPS and TPS–PCL. The process was significantly influenced by the operating temperature and time as well as content of PCL. The samples showed a controlled release of thymol within seven days with a higher amount of released thymol from the TPS–PCL blend. The obtained materials are solvent-free and release the bioactive component in a controlled manner.
PB  - MDPI
T2  - Polymers
T1  - Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics
IS  - 20
SP  - 4360
VL  - 14
DO  - 10.3390/polym14204360
ER  - 

@article{
author = "Lučić Škorić, Marija and Milovanović, Stoja and Žižović, Irena and Ortega-Toro, Rodrigo and Santagata, Gabriella and Malinconico, Mario and Kalagasidis Krušić, Melina",
year = "2022",
abstract = "The aim of the present study was to investigate starch-based materials, prepared in an environmentally friendly way and from renewable resources, suitable for the development of biodegradable active food packaging. For this purpose, a bioactive compound (thymol) was incorporated into thermoplastic starch (TPS) and a TPS blend with poly (ε-caprolactone) (TPS–PCL) by the supercritical CO2 (scCO2) impregnation process. Impregnation experiments with scCO2 were carried out at a pressure of 30 MPa and temperatures in the range of 40–100 °C during 1 to 20 h. The structural, morphological, and thermal properties of the obtained materials were comprehensively evaluated. Bioactive component release kinetic studies were performed in water at 6 °C and 25 °C. It was shown that the scCO2 impregnation process could be successfully employed for thymol loading into TPS and TPS–PCL. The process was significantly influenced by the operating temperature and time as well as content of PCL. The samples showed a controlled release of thymol within seven days with a higher amount of released thymol from the TPS–PCL blend. The obtained materials are solvent-free and release the bioactive component in a controlled manner.",
publisher = "MDPI",
journal = "Polymers",
title = "Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics",
number = "20",
pages = "4360",
volume = "14",
doi = "10.3390/polym14204360"
}

Lučić Škorić, M., Milovanović, S., Žižović, I., Ortega-Toro, R., Santagata, G., Malinconico, M.,& Kalagasidis Krušić, M.. (2022). Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics. in Polymers
MDPI., 14(20), 4360.
https://doi.org/10.3390/polym14204360

Lučić Škorić M, Milovanović S, Žižović I, Ortega-Toro R, Santagata G, Malinconico M, Kalagasidis Krušić M. Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics. in Polymers. 2022;14(20):4360.
doi:10.3390/polym14204360 .

Lučić Škorić, Marija, Milovanović, Stoja, Žižović, Irena, Ortega-Toro, Rodrigo, Santagata, Gabriella, Malinconico, Mario, Kalagasidis Krušić, Melina, "Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics" in Polymers, 14, no. 20 (2022):4360,
https://doi.org/10.3390/polym14204360 . .

TY  - JOUR
AU  - Šešlija, Sanja
AU  - Nešić, Aleksandra
AU  - Ružić, Jovana
AU  - Kalagasidis Krušić, Melina
AU  - Veličković, Sava
AU  - Avolio, Roberto
AU  - Santagata, Gabriella
AU  - Malinconico, Mario
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3951
AB  - The aim of this study was the development of novel polysaccharide based films intended to be used as edible food packaging material. The films were prepared by solution casting method using highly methoxylated pectin (PEC) and poly(ethylene glycol) (PEG) of various molecular weights (400, 600 and 1000 gmol(-1)) in different ratios (5:1, 3:1 and 1:1). The film formation was supported by hydrogen bonding between PEC and PEG, which was evidenced by means of ATR-FTIR and NMR analysis. TGA revealed that generally PEG behaves like a pro-degrading agent for pectin, except in the case of PEC/PEG film with a ratio of 1:1. Furthermore, DSC thermograms indicated that PEG1000 exists as a separate phase in the pectin matrix while the formulations with PEG400 and PEG600 showed mainly amorphous morphology. The addition of PEG enhanced the plasticization of PEC films, as evidenced by progressive decreasing of the glass transition temperature values (T-g). The tensile test measurements showed that increasing concentration of PEG produced weaker and more flexibile films. Due to the increased molecular mobility, the pectin phase became more permeable to water vapor as the PEG concentration increased. The obtained results showed that the combination of both polymers resulted in interesting bio -inspired edible films with the potential to compete with commercially used synthetic package materials.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Hydrocolloids
T1  - Edible blend films of pectin and poly(ethylene glycol): Preparation and physico-chemical evaluation
EP  - 501
SP  - 494
VL  - 77
DO  - 10.1016/j.foodhyd.2017.10.027
ER  - 

@article{
author = "Šešlija, Sanja and Nešić, Aleksandra and Ružić, Jovana and Kalagasidis Krušić, Melina and Veličković, Sava and Avolio, Roberto and Santagata, Gabriella and Malinconico, Mario",
year = "2018",
abstract = "The aim of this study was the development of novel polysaccharide based films intended to be used as edible food packaging material. The films were prepared by solution casting method using highly methoxylated pectin (PEC) and poly(ethylene glycol) (PEG) of various molecular weights (400, 600 and 1000 gmol(-1)) in different ratios (5:1, 3:1 and 1:1). The film formation was supported by hydrogen bonding between PEC and PEG, which was evidenced by means of ATR-FTIR and NMR analysis. TGA revealed that generally PEG behaves like a pro-degrading agent for pectin, except in the case of PEC/PEG film with a ratio of 1:1. Furthermore, DSC thermograms indicated that PEG1000 exists as a separate phase in the pectin matrix while the formulations with PEG400 and PEG600 showed mainly amorphous morphology. The addition of PEG enhanced the plasticization of PEC films, as evidenced by progressive decreasing of the glass transition temperature values (T-g). The tensile test measurements showed that increasing concentration of PEG produced weaker and more flexibile films. Due to the increased molecular mobility, the pectin phase became more permeable to water vapor as the PEG concentration increased. The obtained results showed that the combination of both polymers resulted in interesting bio -inspired edible films with the potential to compete with commercially used synthetic package materials.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Hydrocolloids",
title = "Edible blend films of pectin and poly(ethylene glycol): Preparation and physico-chemical evaluation",
pages = "501-494",
volume = "77",
doi = "10.1016/j.foodhyd.2017.10.027"
}

Šešlija, S., Nešić, A., Ružić, J., Kalagasidis Krušić, M., Veličković, S., Avolio, R., Santagata, G.,& Malinconico, M.. (2018). Edible blend films of pectin and poly(ethylene glycol): Preparation and physico-chemical evaluation. in Food Hydrocolloids
Elsevier Sci Ltd, Oxford., 77, 494-501.
https://doi.org/10.1016/j.foodhyd.2017.10.027

Šešlija S, Nešić A, Ružić J, Kalagasidis Krušić M, Veličković S, Avolio R, Santagata G, Malinconico M. Edible blend films of pectin and poly(ethylene glycol): Preparation and physico-chemical evaluation. in Food Hydrocolloids. 2018;77:494-501.
doi:10.1016/j.foodhyd.2017.10.027 .

Šešlija, Sanja, Nešić, Aleksandra, Ružić, Jovana, Kalagasidis Krušić, Melina, Veličković, Sava, Avolio, Roberto, Santagata, Gabriella, Malinconico, Mario, "Edible blend films of pectin and poly(ethylene glycol): Preparation and physico-chemical evaluation" in Food Hydrocolloids, 77 (2018):494-501,
https://doi.org/10.1016/j.foodhyd.2017.10.027 . .

TY  - JOUR
AU  - Šešlija, Sanja
AU  - Nešić, Aleksandra
AU  - Lučić-Škorić, Marija
AU  - Kalagasidis Krušić, Melina
AU  - Santagata, Gabriella
AU  - Malinconico, Mario
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4038
AB  - The present paper reports on pectin based films modified with carboxymethyl cellulose intended for food packaging. The films are prepared by solvent-casting method with different carboxymethyl cellulose content and cross-linker concentration (Ca2+ ions) in the presence of glycerol as a plasticizer. FT-IR spectra of the prepared films propose that carboxyl group from pectin are mainly involved in interactions with CMC, whereas -OH groups are mainly involved in self-associated hydrogen bonding of neat polymers. Further, an addition of carboxymethyl cellulose improved mechanical properties compared to pure pectin films, while TGA analysis confirmed satisfying thermal stability regarding their potential application as packaging material. Finally, water vapor permeability values are in the range of 1.32x10(-7) up to 2.03x10(-7) wg/m h Pa.
PB  - Wiley-VCH Verlag Gmbh, Weinheim
T2  - Macromolecular Symposia
T1  - Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material
IS  - 1
VL  - 378
DO  - 10.1002/masy.201600163
ER  - 

@article{
author = "Šešlija, Sanja and Nešić, Aleksandra and Lučić-Škorić, Marija and Kalagasidis Krušić, Melina and Santagata, Gabriella and Malinconico, Mario",
year = "2018",
abstract = "The present paper reports on pectin based films modified with carboxymethyl cellulose intended for food packaging. The films are prepared by solvent-casting method with different carboxymethyl cellulose content and cross-linker concentration (Ca2+ ions) in the presence of glycerol as a plasticizer. FT-IR spectra of the prepared films propose that carboxyl group from pectin are mainly involved in interactions with CMC, whereas -OH groups are mainly involved in self-associated hydrogen bonding of neat polymers. Further, an addition of carboxymethyl cellulose improved mechanical properties compared to pure pectin films, while TGA analysis confirmed satisfying thermal stability regarding their potential application as packaging material. Finally, water vapor permeability values are in the range of 1.32x10(-7) up to 2.03x10(-7) wg/m h Pa.",
publisher = "Wiley-VCH Verlag Gmbh, Weinheim",
journal = "Macromolecular Symposia",
title = "Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material",
number = "1",
volume = "378",
doi = "10.1002/masy.201600163"
}

Šešlija, S., Nešić, A., Lučić-Škorić, M., Kalagasidis Krušić, M., Santagata, G.,& Malinconico, M.. (2018). Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material. in Macromolecular Symposia
Wiley-VCH Verlag Gmbh, Weinheim., 378(1).
https://doi.org/10.1002/masy.201600163

Šešlija S, Nešić A, Lučić-Škorić M, Kalagasidis Krušić M, Santagata G, Malinconico M. Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material. in Macromolecular Symposia. 2018;378(1).
doi:10.1002/masy.201600163 .

Šešlija, Sanja, Nešić, Aleksandra, Lučić-Škorić, Marija, Kalagasidis Krušić, Melina, Santagata, Gabriella, Malinconico, Mario, "Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material" in Macromolecular Symposia, 378, no. 1 (2018),
https://doi.org/10.1002/masy.201600163 . .

TY  - JOUR
AU  - Nešić, Aleksandra
AU  - Onjia, Antonije
AU  - Davidović, Slađana
AU  - Dimitrijević, Suzana
AU  - Errico, Maria Emanuela
AU  - Santagata, Gabriella
AU  - Malinconico, Mario
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3671
AB  - In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity
EP  - 990
SP  - 981
VL  - 157
DO  - 10.1016/j.carbpol.2016.10.054
ER  - 

@article{
author = "Nešić, Aleksandra and Onjia, Antonije and Davidović, Slađana and Dimitrijević, Suzana and Errico, Maria Emanuela and Santagata, Gabriella and Malinconico, Mario",
year = "2017",
abstract = "In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity",
pages = "990-981",
volume = "157",
doi = "10.1016/j.carbpol.2016.10.054"
}

Nešić, A., Onjia, A., Davidović, S., Dimitrijević, S., Errico, M. E., Santagata, G.,& Malinconico, M.. (2017). Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 157, 981-990.
https://doi.org/10.1016/j.carbpol.2016.10.054

Nešić A, Onjia A, Davidović S, Dimitrijević S, Errico ME, Santagata G, Malinconico M. Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers. 2017;157:981-990.
doi:10.1016/j.carbpol.2016.10.054 .

Nešić, Aleksandra, Onjia, Antonije, Davidović, Slađana, Dimitrijević, Suzana, Errico, Maria Emanuela, Santagata, Gabriella, Malinconico, Mario, "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity" in Carbohydrate Polymers, 157 (2017):981-990,
https://doi.org/10.1016/j.carbpol.2016.10.054 . .