Lazarević-Pašti, Tamara

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orcid::0000-0001-6220-2079
  • Lazarević-Pašti, Tamara (6)
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Author's Bibliography

Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal

Katnić, Đurica B.; Porobić, Slavica J.; Vujčić, Ivica; Kojić, Marija M.; Lazarević-Pašti, Tamara; Milanković, Vedran; Marinović-Cincović, Milena; Živojinović, Dragana Z.

(Elsevier Ltd, 2024)

TY  - JOUR
AU  - Katnić, Đurica B.
AU  - Porobić, Slavica J.
AU  - Vujčić, Ivica
AU  - Kojić, Marija M.
AU  - Lazarević-Pašti, Tamara
AU  - Milanković, Vedran
AU  - Marinović-Cincović, Milena
AU  - Živojinović, Dragana Z.
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6633
AB  - Irradiated fig pomace pyrochar (IrrPyrFP) is noteworthy as a novel sterilized low-cost sorbent of BTEX, pesticides, and Pb2+ ions. It was produced by applying pyrolysis treatment followed by gamma irradiation modification in order to obtain a highly efficient and sterile sorbent. The characterization of fig pomace before and after pyrolysis, as well as before and after irradiation of the obtained pyrochar, was done using SEM, FTIR, and elemental analysis, while its sorption ability was tested through the removal of examined pollutants by batch sorption experiments. The obtained results suggest that IrrPyrFP could play a significant role in the control of environmental pollutants, as indicated by the maximum adsorption capacities: 42 mg g−1 for BTEX, 0.625 mg g−1 for malathion, 0.495 mg g−1 for chlorpyrifos and 255 mg g−1 for Pb2+. A kinetic study showed that the removal process by IrrPyrFP mainly follows pseudo 2nd kinetics order, while the sorption equilibriums were estimated using the Langmuir and Freundlich model. Overall, the findings of this work suggest that pyrolysis and activation by irradiation of waste biomass is a promising way to produce sterile efficient sorbents for waste-water treatment based on green chemistry. Additionally, the demonstrated application of fig pomace promotes the potential of using this biomass for continual and economical waste management in the rising fig industry.
PB  - Elsevier Ltd
T2  - Radiation Physics and Chemistry
T1  - Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal
SP  - 111277
VL  - 214
DO  - 10.1016/j.radphyschem.2023.111277
ER  - 
@article{
author = "Katnić, Đurica B. and Porobić, Slavica J. and Vujčić, Ivica and Kojić, Marija M. and Lazarević-Pašti, Tamara and Milanković, Vedran and Marinović-Cincović, Milena and Živojinović, Dragana Z.",
year = "2024",
abstract = "Irradiated fig pomace pyrochar (IrrPyrFP) is noteworthy as a novel sterilized low-cost sorbent of BTEX, pesticides, and Pb2+ ions. It was produced by applying pyrolysis treatment followed by gamma irradiation modification in order to obtain a highly efficient and sterile sorbent. The characterization of fig pomace before and after pyrolysis, as well as before and after irradiation of the obtained pyrochar, was done using SEM, FTIR, and elemental analysis, while its sorption ability was tested through the removal of examined pollutants by batch sorption experiments. The obtained results suggest that IrrPyrFP could play a significant role in the control of environmental pollutants, as indicated by the maximum adsorption capacities: 42 mg g−1 for BTEX, 0.625 mg g−1 for malathion, 0.495 mg g−1 for chlorpyrifos and 255 mg g−1 for Pb2+. A kinetic study showed that the removal process by IrrPyrFP mainly follows pseudo 2nd kinetics order, while the sorption equilibriums were estimated using the Langmuir and Freundlich model. Overall, the findings of this work suggest that pyrolysis and activation by irradiation of waste biomass is a promising way to produce sterile efficient sorbents for waste-water treatment based on green chemistry. Additionally, the demonstrated application of fig pomace promotes the potential of using this biomass for continual and economical waste management in the rising fig industry.",
publisher = "Elsevier Ltd",
journal = "Radiation Physics and Chemistry",
title = "Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal",
pages = "111277",
volume = "214",
doi = "10.1016/j.radphyschem.2023.111277"
}
Katnić, Đ. B., Porobić, S. J., Vujčić, I., Kojić, M. M., Lazarević-Pašti, T., Milanković, V., Marinović-Cincović, M.,& Živojinović, D. Z.. (2024). Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal. in Radiation Physics and Chemistry
Elsevier Ltd., 214, 111277.
https://doi.org/10.1016/j.radphyschem.2023.111277
Katnić ĐB, Porobić SJ, Vujčić I, Kojić MM, Lazarević-Pašti T, Milanković V, Marinović-Cincović M, Živojinović DZ. Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal. in Radiation Physics and Chemistry. 2024;214:111277.
doi:10.1016/j.radphyschem.2023.111277 .
Katnić, Đurica B., Porobić, Slavica J., Vujčić, Ivica, Kojić, Marija M., Lazarević-Pašti, Tamara, Milanković, Vedran, Marinović-Cincović, Milena, Živojinović, Dragana Z., "Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal" in Radiation Physics and Chemistry, 214 (2024):111277,
https://doi.org/10.1016/j.radphyschem.2023.111277 . .
2
1

Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors

Laban, Bojana B.; Lazarević-Pašti, Tamara; Veljović, Đorđe; Marković, Mirjana; Klekotka, Urszula

(John Wiley and Sons Inc., 2023)

TY  - JOUR
AU  - Laban, Bojana B.
AU  - Lazarević-Pašti, Tamara
AU  - Veljović, Đorđe
AU  - Marković, Mirjana
AU  - Klekotka, Urszula
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6222
AB  - The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.
PB  - John Wiley and Sons Inc.
T2  - European Journal of Inorganic Chemistry
T1  - Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors
SP  - e202200754
DO  - 10.1002/ejic.202200754
ER  - 
@article{
author = "Laban, Bojana B. and Lazarević-Pašti, Tamara and Veljović, Đorđe and Marković, Mirjana and Klekotka, Urszula",
year = "2023",
abstract = "The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.",
publisher = "John Wiley and Sons Inc.",
journal = "European Journal of Inorganic Chemistry",
title = "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors",
pages = "e202200754",
doi = "10.1002/ejic.202200754"
}
Laban, B. B., Lazarević-Pašti, T., Veljović, Đ., Marković, M.,& Klekotka, U.. (2023). Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry
John Wiley and Sons Inc.., e202200754.
https://doi.org/10.1002/ejic.202200754
Laban BB, Lazarević-Pašti T, Veljović Đ, Marković M, Klekotka U. Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry. 2023;:e202200754.
doi:10.1002/ejic.202200754 .
Laban, Bojana B., Lazarević-Pašti, Tamara, Veljović, Đorđe, Marković, Mirjana, Klekotka, Urszula, "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors" in European Journal of Inorganic Chemistry (2023):e202200754,
https://doi.org/10.1002/ejic.202200754 . .
2

Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants

Katnić, Đurica; Porobić, Slavica J.; Lazarević-Pašti, Tamara; Kojić, Marija; Tasić, Tamara; Marinović-Cincović, Milena; Živojinović, Dragana

(2023)

TY  - JOUR
AU  - Katnić, Đurica
AU  - Porobić, Slavica J.
AU  - Lazarević-Pašti, Tamara
AU  - Kojić, Marija
AU  - Tasić, Tamara
AU  - Marinović-Cincović, Milena
AU  - Živojinović, Dragana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11871
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6802
AB  - The removal of environmental pollutants is significant because of their harmful effects on living organisms. Biochar is favorable as a natural adsorbent of environmental pollutants due to its advantages, such as environmental acceptability and economic profitability. This study evaluated the potential of pyrolyzed plum pomace (PyrPP) as an adsorbent for environmental pollutants: Pb2+ ions, pesticides (chlorpyrifos and malathion), as well as organic pollutants BTEX. In order to ameliorate the adsorption capacity of PyrPP, modification by gamma irradiation was performed. Irradiated plum pomace biochar (IrPyrPP) has been shown to be an effective adsorbent, and the material is also sterilized by irradiation, which makes this material potentially sterile adsorbents of the most environmental pollutants from water. The irradiated biochar showed better adsorption performances for the removal of Pb2+ ions, BTEX, and chlorpyrifos. Maximum adsorption capacity (Qmax) of PyrPP for Pb2+, BTEX, chlorpyrifos, and malathion adsorption was 157.0, 17.6, 0.219, and 1.067 mg g− 1 , while Qmax of IrPyrPP for Pb2+, BTEX, chlorpyrifos and malathion was 271.0, 48.0, 0.428 and 0.593 mg g− 1 , respectively. The results obtained during this research suggest that biomass pyrolysis and modification of this biomass by irradiation is a promising way to produce efficient natural sterile sorbents for wastewater treatment.
T2  - Journal of Water Process Engineering
T1  - Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants
SP  - 104487
VL  - 56
DO  - 10.1016/j.jwpe.2023.104487
ER  - 
@article{
author = "Katnić, Đurica and Porobić, Slavica J. and Lazarević-Pašti, Tamara and Kojić, Marija and Tasić, Tamara and Marinović-Cincović, Milena and Živojinović, Dragana",
year = "2023",
abstract = "The removal of environmental pollutants is significant because of their harmful effects on living organisms. Biochar is favorable as a natural adsorbent of environmental pollutants due to its advantages, such as environmental acceptability and economic profitability. This study evaluated the potential of pyrolyzed plum pomace (PyrPP) as an adsorbent for environmental pollutants: Pb2+ ions, pesticides (chlorpyrifos and malathion), as well as organic pollutants BTEX. In order to ameliorate the adsorption capacity of PyrPP, modification by gamma irradiation was performed. Irradiated plum pomace biochar (IrPyrPP) has been shown to be an effective adsorbent, and the material is also sterilized by irradiation, which makes this material potentially sterile adsorbents of the most environmental pollutants from water. The irradiated biochar showed better adsorption performances for the removal of Pb2+ ions, BTEX, and chlorpyrifos. Maximum adsorption capacity (Qmax) of PyrPP for Pb2+, BTEX, chlorpyrifos, and malathion adsorption was 157.0, 17.6, 0.219, and 1.067 mg g− 1 , while Qmax of IrPyrPP for Pb2+, BTEX, chlorpyrifos and malathion was 271.0, 48.0, 0.428 and 0.593 mg g− 1 , respectively. The results obtained during this research suggest that biomass pyrolysis and modification of this biomass by irradiation is a promising way to produce efficient natural sterile sorbents for wastewater treatment.",
journal = "Journal of Water Process Engineering",
title = "Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants",
pages = "104487",
volume = "56",
doi = "10.1016/j.jwpe.2023.104487"
}
Katnić, Đ., Porobić, S. J., Lazarević-Pašti, T., Kojić, M., Tasić, T., Marinović-Cincović, M.,& Živojinović, D.. (2023). Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants. in Journal of Water Process Engineering, 56, 104487.
https://doi.org/10.1016/j.jwpe.2023.104487
Katnić Đ, Porobić SJ, Lazarević-Pašti T, Kojić M, Tasić T, Marinović-Cincović M, Živojinović D. Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants. in Journal of Water Process Engineering. 2023;56:104487.
doi:10.1016/j.jwpe.2023.104487 .
Katnić, Đurica, Porobić, Slavica J., Lazarević-Pašti, Tamara, Kojić, Marija, Tasić, Tamara, Marinović-Cincović, Milena, Živojinović, Dragana, "Sterilized plum pomace biochar as a low-cost effective sorbent of environmental contaminants" in Journal of Water Process Engineering, 56 (2023):104487,
https://doi.org/10.1016/j.jwpe.2023.104487 . .
2
2

Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water

Lazarević-Pašti, Tamara; Pašti, Igor A.; Jokić, Bojan M.; Babić, Biljana M.; Vasić, Vesna M.

(Royal Society of Chemistry, 2016)

TY  - JOUR
AU  - Lazarević-Pašti, Tamara
AU  - Pašti, Igor A.
AU  - Jokić, Bojan M.
AU  - Babić, Biljana M.
AU  - Vasić, Vesna M.
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5828
AB  - Extensive use of organophosphate pesticides (OPs) invokes development of efficient procedures for their removal from the environment. By introducing low levels ( LT 1 at%) of B, N or P into the structure of mesoporous carbons, we have produced a series of materials with different surface chemical composition, textural properties and level of structural disorder. These adsorbents were applied for removal of dimethoate and its oxo-analogue omethoate from aqueous solutions under batch adsorption conditions and by filtration using modified nylon membrane filters. Adsorption capacities up to 164 mg g(-1) were measured, with OPs uptake typically above 80% for dimethoate concentration as high as 5 x 10(-3) mol dm(-3). After the adsorption, neurotoxic effects of OP-containing water samples were significantly reduced or completely removed. The level of structural disorder was identified as a key parameter for efficient removal of dimethoate and omethoate while in the filtration experiments surface area of adsorbents also played an important role. While the presented research appeals to new fundamental studies of OP-carbon surface interactions, it also indicates a possible strategy in designing new efficient adsorbents for OPs removal from water.
PB  - Royal Society of Chemistry
T2  - RSC Advances
T1  - Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water
EP  - 62139
IS  - 67
SP  - 62128
VL  - 6
DO  - 10.1039/c6ra06736k
ER  - 
@article{
author = "Lazarević-Pašti, Tamara and Pašti, Igor A. and Jokić, Bojan M. and Babić, Biljana M. and Vasić, Vesna M.",
year = "2016",
abstract = "Extensive use of organophosphate pesticides (OPs) invokes development of efficient procedures for their removal from the environment. By introducing low levels ( LT 1 at%) of B, N or P into the structure of mesoporous carbons, we have produced a series of materials with different surface chemical composition, textural properties and level of structural disorder. These adsorbents were applied for removal of dimethoate and its oxo-analogue omethoate from aqueous solutions under batch adsorption conditions and by filtration using modified nylon membrane filters. Adsorption capacities up to 164 mg g(-1) were measured, with OPs uptake typically above 80% for dimethoate concentration as high as 5 x 10(-3) mol dm(-3). After the adsorption, neurotoxic effects of OP-containing water samples were significantly reduced or completely removed. The level of structural disorder was identified as a key parameter for efficient removal of dimethoate and omethoate while in the filtration experiments surface area of adsorbents also played an important role. While the presented research appeals to new fundamental studies of OP-carbon surface interactions, it also indicates a possible strategy in designing new efficient adsorbents for OPs removal from water.",
publisher = "Royal Society of Chemistry",
journal = "RSC Advances",
title = "Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water",
pages = "62139-62128",
number = "67",
volume = "6",
doi = "10.1039/c6ra06736k"
}
Lazarević-Pašti, T., Pašti, I. A., Jokić, B. M., Babić, B. M.,& Vasić, V. M.. (2016). Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water. in RSC Advances
Royal Society of Chemistry., 6(67), 62128-62139.
https://doi.org/10.1039/c6ra06736k
Lazarević-Pašti T, Pašti IA, Jokić BM, Babić BM, Vasić VM. Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water. in RSC Advances. 2016;6(67):62128-62139.
doi:10.1039/c6ra06736k .
Lazarević-Pašti, Tamara, Pašti, Igor A., Jokić, Bojan M., Babić, Biljana M., Vasić, Vesna M., "Heteroatom-doped mesoporous carbons as efficient adsorbents for removal of dimethoate and omethoate from water" in RSC Advances, 6, no. 67 (2016):62128-62139,
https://doi.org/10.1039/c6ra06736k . .
32
18
34

Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts

Nastasijević, Branislav J.; Lazarević-Pašti, Tamara; Dimitrijević-Branković, Suzana; Pašti, Igor A.; Vujačić, Ana V.; Joksić, Gordana; Vasić, Vesna M.

(Elsevier, Amsterdam, 2012)

TY  - JOUR
AU  - Nastasijević, Branislav J.
AU  - Lazarević-Pašti, Tamara
AU  - Dimitrijević-Branković, Suzana
AU  - Pašti, Igor A.
AU  - Vujačić, Ana V.
AU  - Joksić, Gordana
AU  - Vasić, Vesna M.
PY  - 2012
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2130
AB  - The aim of this study was to investigate the inhibitory activity of Gentiana lutea extracts on the enzyme myeloperoxidase (MPO), as well as the antioxidant activity of these extracts and their correlation with the total polyphenol content. Extracts were prepared using methanol (100%), water and ethanol aqueous solutions (96, 75, 50 and 25% v/v) as solvents for extraction. Also, isovitexin, amarogentin and gentiopicroside, pharmacologically active constituents of G. lutea were tested as potential inhibitors of MPO. Antioxidant activity of extracts was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging test and also using cyclic voltammetry (CV). Among all extracts, the antioxidant capacity of 50% ethanol aqueous extract was the highest, both when measured using the DPPH test, with IC50 = 20.6 mu g/ml, and when using CV. Also, 50% ethanol extract, showed the best inhibition of MPO activity in comparison with other extracts. In the group of the selected G. lutea constituents, gentiopicroside has proved to be the strongest inhibitor of MPO, with IC50 = 0.8 mu g/ml. Also, the concentration of G. lutea constituents were determined in all extracts, using Ultra Performance Liquid Chromatography (UPLC).
PB  - Elsevier, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts
EP  - 196
SP  - 191
VL  - 66
DO  - 10.1016/j.jpba.2012.03.052
ER  - 
@article{
author = "Nastasijević, Branislav J. and Lazarević-Pašti, Tamara and Dimitrijević-Branković, Suzana and Pašti, Igor A. and Vujačić, Ana V. and Joksić, Gordana and Vasić, Vesna M.",
year = "2012",
abstract = "The aim of this study was to investigate the inhibitory activity of Gentiana lutea extracts on the enzyme myeloperoxidase (MPO), as well as the antioxidant activity of these extracts and their correlation with the total polyphenol content. Extracts were prepared using methanol (100%), water and ethanol aqueous solutions (96, 75, 50 and 25% v/v) as solvents for extraction. Also, isovitexin, amarogentin and gentiopicroside, pharmacologically active constituents of G. lutea were tested as potential inhibitors of MPO. Antioxidant activity of extracts was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging test and also using cyclic voltammetry (CV). Among all extracts, the antioxidant capacity of 50% ethanol aqueous extract was the highest, both when measured using the DPPH test, with IC50 = 20.6 mu g/ml, and when using CV. Also, 50% ethanol extract, showed the best inhibition of MPO activity in comparison with other extracts. In the group of the selected G. lutea constituents, gentiopicroside has proved to be the strongest inhibitor of MPO, with IC50 = 0.8 mu g/ml. Also, the concentration of G. lutea constituents were determined in all extracts, using Ultra Performance Liquid Chromatography (UPLC).",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts",
pages = "196-191",
volume = "66",
doi = "10.1016/j.jpba.2012.03.052"
}
Nastasijević, B. J., Lazarević-Pašti, T., Dimitrijević-Branković, S., Pašti, I. A., Vujačić, A. V., Joksić, G.,& Vasić, V. M.. (2012). Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier, Amsterdam., 66, 191-196.
https://doi.org/10.1016/j.jpba.2012.03.052
Nastasijević BJ, Lazarević-Pašti T, Dimitrijević-Branković S, Pašti IA, Vujačić AV, Joksić G, Vasić VM. Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts. in Journal of Pharmaceutical and Biomedical Analysis. 2012;66:191-196.
doi:10.1016/j.jpba.2012.03.052 .
Nastasijević, Branislav J., Lazarević-Pašti, Tamara, Dimitrijević-Branković, Suzana, Pašti, Igor A., Vujačić, Ana V., Joksić, Gordana, Vasić, Vesna M., "Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts" in Journal of Pharmaceutical and Biomedical Analysis, 66 (2012):191-196,
https://doi.org/10.1016/j.jpba.2012.03.052 . .
58
46
62

Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods

Lazarević-Pašti, Tamara; Momić, Tatjana; Onjia, Antonije; Vujisić, Ljubodrag V.; Vasić, Vesna M.

(Springer Wien, Wien, 2010)

TY  - JOUR
AU  - Lazarević-Pašti, Tamara
AU  - Momić, Tatjana
AU  - Onjia, Antonije
AU  - Vujisić, Ljubodrag V.
AU  - Vasić, Vesna M.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1639
AB  - In order to improve the sensitivity of assays for inhibitors of the enzyme acetylcholine esterase (AChE), an effective method was developed for the conversion of the organophosphate pesticides (OPs) diazinon, malathion, chlorpyrifos, azinphos-methyl and phorate into more toxic inhibitors. This was accomplished by converting them from the thio form into their oxo form using the enzyme myeloperoxidase. The oxo forms, which are the only products of conversion, were determined by AChE bioassays, using either the free enzyme, or a flow injection analysis manifold with immobilized AChE and spectrophotometric detection. All modified OPs exhibited inhibitory power at ppb levels and within 10 min. The method is considered to represent an excellent means for improving the sensitivity of assays for determination of OPs.
PB  - Springer Wien, Wien
T2  - Microchimica Acta
T1  - Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods
EP  - 297
IS  - 3-4
SP  - 289
VL  - 170
DO  - 10.1007/s00604-010-0324-2
ER  - 
@article{
author = "Lazarević-Pašti, Tamara and Momić, Tatjana and Onjia, Antonije and Vujisić, Ljubodrag V. and Vasić, Vesna M.",
year = "2010",
abstract = "In order to improve the sensitivity of assays for inhibitors of the enzyme acetylcholine esterase (AChE), an effective method was developed for the conversion of the organophosphate pesticides (OPs) diazinon, malathion, chlorpyrifos, azinphos-methyl and phorate into more toxic inhibitors. This was accomplished by converting them from the thio form into their oxo form using the enzyme myeloperoxidase. The oxo forms, which are the only products of conversion, were determined by AChE bioassays, using either the free enzyme, or a flow injection analysis manifold with immobilized AChE and spectrophotometric detection. All modified OPs exhibited inhibitory power at ppb levels and within 10 min. The method is considered to represent an excellent means for improving the sensitivity of assays for determination of OPs.",
publisher = "Springer Wien, Wien",
journal = "Microchimica Acta",
title = "Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods",
pages = "297-289",
number = "3-4",
volume = "170",
doi = "10.1007/s00604-010-0324-2"
}
Lazarević-Pašti, T., Momić, T., Onjia, A., Vujisić, L. V.,& Vasić, V. M.. (2010). Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods. in Microchimica Acta
Springer Wien, Wien., 170(3-4), 289-297.
https://doi.org/10.1007/s00604-010-0324-2
Lazarević-Pašti T, Momić T, Onjia A, Vujisić LV, Vasić VM. Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods. in Microchimica Acta. 2010;170(3-4):289-297.
doi:10.1007/s00604-010-0324-2 .
Lazarević-Pašti, Tamara, Momić, Tatjana, Onjia, Antonije, Vujisić, Ljubodrag V., Vasić, Vesna M., "Myeloperoxidase-mediated oxidation of organophosphorus pesticides as a pre-step in their determination by AChE based bioanalytical methods" in Microchimica Acta, 170, no. 3-4 (2010):289-297,
https://doi.org/10.1007/s00604-010-0324-2 . .
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