TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Stanković, Milica
AU  - Roganović, Sonja
AU  - Nešić, Ivana
AU  - Zvezdanović, Jelena
AU  - Tadić, Vanja
AU  - Žižović, Irena
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5230
AB  - Ethnopharmacological relevance: Helichrysum italicum has been widely used in traditional medicine to treat allergies, colds, cough, skin, liver and gallbladder disorders, inflammation, infections, and sleeplessness. Furthermore, it possesses considerable wound healing and skin protective properties, documented by several in vivo studies performed on animals. However, there is a lack of experimental evidence supporting its potential as a topical agent tested by human clinical trials. Aim of the study: The study aimed to investigate the skin protective activity of cotton gauze and polypropylene non-woven fabric, impregnated with H. italicum extract by the integrated supercritical CO2 extraction-supercritical solvent impregnation process. Materials and methods: The integrated process of supercritical CO2 extraction of H. italicum and the impregnation of cotton gauze and polypropylene non-woven fabric was performed under 350 bar and 40 °C with and without the addition of ethanol as a cosolvent. Impregnated textile materials were tested in vivo for their bioactivity on irritated human skin. Randomized in vivo studies performed involved assays of both safety and efficacy of the impregnated textiles. The effects were evaluated using the in vivo non-invasive biophysical measurements of the following skin parameters: electrical capacitance, transepidermal water loss, melanin index, erythema index, and skin pH. Results: Both cotton gauze and polypropylene non-woven fabric were impregnated with H. italicum extracts under supercritical conditions with considerable values of the impregnation yield (1.97%–4.25%). The addition of ethanol as a cosolvent during the process caused significant changes in the incorporated extracts’ impregnation yield and chemical profile. Both impregnated textile materials were safe, evaluated by their testing on the human skin with no cause of any irritation and redness. However, efficacy studies revealed that polypropylene non-woven fabric impregnated with H. italicum extract with ethanol as a cosolvent, possessed significantly greater potential for skin protection than the other investigated samples. Conclusions: The present study demonstrated the feasibility of the combined supercritical extraction and impregnation process in developing materials for topical application based on H. italicum extract. The results of in vivo studies performed on human volunteers confirmed the suitability of H. italicum active components to be a part of human skin protective preparations because of their ability to maintain the skin unimpaired. Traditionally claimed applications as a medicinal plant capable of regenerating skin have been scientifically proven, in addition to employing green technology in obtaining the impregnated materials with a broad spectrum of utilization.
PB  - Elsevier Ireland Ltd
T2  - Journal of Ethnopharmacology
T1  - Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin
SP  - 115779
VL  - 301
DO  - 10.1016/j.jep.2022.115779
ER  - 

@article{
author = "Maksimović, Svetolik and Stanković, Milica and Roganović, Sonja and Nešić, Ivana and Zvezdanović, Jelena and Tadić, Vanja and Žižović, Irena",
year = "2023",
abstract = "Ethnopharmacological relevance: Helichrysum italicum has been widely used in traditional medicine to treat allergies, colds, cough, skin, liver and gallbladder disorders, inflammation, infections, and sleeplessness. Furthermore, it possesses considerable wound healing and skin protective properties, documented by several in vivo studies performed on animals. However, there is a lack of experimental evidence supporting its potential as a topical agent tested by human clinical trials. Aim of the study: The study aimed to investigate the skin protective activity of cotton gauze and polypropylene non-woven fabric, impregnated with H. italicum extract by the integrated supercritical CO2 extraction-supercritical solvent impregnation process. Materials and methods: The integrated process of supercritical CO2 extraction of H. italicum and the impregnation of cotton gauze and polypropylene non-woven fabric was performed under 350 bar and 40 °C with and without the addition of ethanol as a cosolvent. Impregnated textile materials were tested in vivo for their bioactivity on irritated human skin. Randomized in vivo studies performed involved assays of both safety and efficacy of the impregnated textiles. The effects were evaluated using the in vivo non-invasive biophysical measurements of the following skin parameters: electrical capacitance, transepidermal water loss, melanin index, erythema index, and skin pH. Results: Both cotton gauze and polypropylene non-woven fabric were impregnated with H. italicum extracts under supercritical conditions with considerable values of the impregnation yield (1.97%–4.25%). The addition of ethanol as a cosolvent during the process caused significant changes in the incorporated extracts’ impregnation yield and chemical profile. Both impregnated textile materials were safe, evaluated by their testing on the human skin with no cause of any irritation and redness. However, efficacy studies revealed that polypropylene non-woven fabric impregnated with H. italicum extract with ethanol as a cosolvent, possessed significantly greater potential for skin protection than the other investigated samples. Conclusions: The present study demonstrated the feasibility of the combined supercritical extraction and impregnation process in developing materials for topical application based on H. italicum extract. The results of in vivo studies performed on human volunteers confirmed the suitability of H. italicum active components to be a part of human skin protective preparations because of their ability to maintain the skin unimpaired. Traditionally claimed applications as a medicinal plant capable of regenerating skin have been scientifically proven, in addition to employing green technology in obtaining the impregnated materials with a broad spectrum of utilization.",
publisher = "Elsevier Ireland Ltd",
journal = "Journal of Ethnopharmacology",
title = "Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin",
pages = "115779",
volume = "301",
doi = "10.1016/j.jep.2022.115779"
}

Maksimović, S., Stanković, M., Roganović, S., Nešić, I., Zvezdanović, J., Tadić, V.,& Žižović, I.. (2023). Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin. in Journal of Ethnopharmacology
Elsevier Ireland Ltd., 301, 115779.
https://doi.org/10.1016/j.jep.2022.115779

Maksimović S, Stanković M, Roganović S, Nešić I, Zvezdanović J, Tadić V, Žižović I. Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin. in Journal of Ethnopharmacology. 2023;301:115779.
doi:10.1016/j.jep.2022.115779 .

Maksimović, Svetolik, Stanković, Milica, Roganović, Sonja, Nešić, Ivana, Zvezdanović, Jelena, Tadić, Vanja, Žižović, Irena, "Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin" in Journal of Ethnopharmacology, 301 (2023):115779,
https://doi.org/10.1016/j.jep.2022.115779 . .

TY  - JOUR
AU  - Lučić Škorić, Marija
AU  - Milovanović, Stoja
AU  - Žižović, Irena
AU  - Ortega-Toro, Rodrigo
AU  - Santagata, Gabriella
AU  - Malinconico, Mario
AU  - Kalagasidis Krušić, Melina
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5243
AB  - The aim of the present study was to investigate starch-based materials, prepared in an environmentally friendly way and from renewable resources, suitable for the development of biodegradable active food packaging. For this purpose, a bioactive compound (thymol) was incorporated into thermoplastic starch (TPS) and a TPS blend with poly (ε-caprolactone) (TPS–PCL) by the supercritical CO2 (scCO2) impregnation process. Impregnation experiments with scCO2 were carried out at a pressure of 30 MPa and temperatures in the range of 40–100 °C during 1 to 20 h. The structural, morphological, and thermal properties of the obtained materials were comprehensively evaluated. Bioactive component release kinetic studies were performed in water at 6 °C and 25 °C. It was shown that the scCO2 impregnation process could be successfully employed for thymol loading into TPS and TPS–PCL. The process was significantly influenced by the operating temperature and time as well as content of PCL. The samples showed a controlled release of thymol within seven days with a higher amount of released thymol from the TPS–PCL blend. The obtained materials are solvent-free and release the bioactive component in a controlled manner.
PB  - MDPI
T2  - Polymers
T1  - Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics
IS  - 20
SP  - 4360
VL  - 14
DO  - 10.3390/polym14204360
ER  - 

@article{
author = "Lučić Škorić, Marija and Milovanović, Stoja and Žižović, Irena and Ortega-Toro, Rodrigo and Santagata, Gabriella and Malinconico, Mario and Kalagasidis Krušić, Melina",
year = "2022",
abstract = "The aim of the present study was to investigate starch-based materials, prepared in an environmentally friendly way and from renewable resources, suitable for the development of biodegradable active food packaging. For this purpose, a bioactive compound (thymol) was incorporated into thermoplastic starch (TPS) and a TPS blend with poly (ε-caprolactone) (TPS–PCL) by the supercritical CO2 (scCO2) impregnation process. Impregnation experiments with scCO2 were carried out at a pressure of 30 MPa and temperatures in the range of 40–100 °C during 1 to 20 h. The structural, morphological, and thermal properties of the obtained materials were comprehensively evaluated. Bioactive component release kinetic studies were performed in water at 6 °C and 25 °C. It was shown that the scCO2 impregnation process could be successfully employed for thymol loading into TPS and TPS–PCL. The process was significantly influenced by the operating temperature and time as well as content of PCL. The samples showed a controlled release of thymol within seven days with a higher amount of released thymol from the TPS–PCL blend. The obtained materials are solvent-free and release the bioactive component in a controlled manner.",
publisher = "MDPI",
journal = "Polymers",
title = "Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics",
number = "20",
pages = "4360",
volume = "14",
doi = "10.3390/polym14204360"
}

Lučić Škorić, M., Milovanović, S., Žižović, I., Ortega-Toro, R., Santagata, G., Malinconico, M.,& Kalagasidis Krušić, M.. (2022). Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics. in Polymers
MDPI., 14(20), 4360.
https://doi.org/10.3390/polym14204360

Lučić Škorić M, Milovanović S, Žižović I, Ortega-Toro R, Santagata G, Malinconico M, Kalagasidis Krušić M. Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics. in Polymers. 2022;14(20):4360.
doi:10.3390/polym14204360 .

Lučić Škorić, Marija, Milovanović, Stoja, Žižović, Irena, Ortega-Toro, Rodrigo, Santagata, Gabriella, Malinconico, Mario, Kalagasidis Krušić, Melina, "Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics" in Polymers, 14, no. 20 (2022):4360,
https://doi.org/10.3390/polym14204360 . .

TY  - JOUR
AU  - Lukić, Ivana
AU  - Pajnik, Jelena
AU  - Nišavić, Jakov
AU  - Tadić, Vanja
AU  - Vági, Erika
AU  - Szekely, Edit
AU  - Žižović, Irena
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5113
AB  - The integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated materials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1).
PB  - MDPI
T2  - Processes
T1  - Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties
IS  - 4
SP  - 680
VL  - 10
DO  - 10.3390/pr10040680
ER  - 

@article{
author = "Lukić, Ivana and Pajnik, Jelena and Nišavić, Jakov and Tadić, Vanja and Vági, Erika and Szekely, Edit and Žižović, Irena",
year = "2022",
abstract = "The integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated materials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1).",
publisher = "MDPI",
journal = "Processes",
title = "Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties",
number = "4",
pages = "680",
volume = "10",
doi = "10.3390/pr10040680"
}

Lukić, I., Pajnik, J., Nišavić, J., Tadić, V., Vági, E., Szekely, E.,& Žižović, I.. (2022). Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties. in Processes
MDPI., 10(4), 680.
https://doi.org/10.3390/pr10040680

Lukić I, Pajnik J, Nišavić J, Tadić V, Vági E, Szekely E, Žižović I. Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties. in Processes. 2022;10(4):680.
doi:10.3390/pr10040680 .

Lukić, Ivana, Pajnik, Jelena, Nišavić, Jakov, Tadić, Vanja, Vági, Erika, Szekely, Edit, Žižović, Irena, "Application of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Properties" in Processes, 10, no. 4 (2022):680,
https://doi.org/10.3390/pr10040680 . .

TY  - JOUR
AU  - Malićanin, Marko
AU  - Milanović, Jelena
AU  - Žižović, Irena
AU  - Ivanović, Jasna
AU  - Milovanović, Stoja
AU  - Rakić, Vesna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6877
AB  - In this work, the extraction by supercritical carbon dioxide of grapeseed oil from five red grape varieties was investigated. Apart from an indigenous variety Prokupac, as the domestic, and Merlot and Cabernet Sauvignon, as international grape varieties the most represented in the Republic of Serbia, Pinot Noir and Gamay were studied as well. Extraction conditions were: temperature of 50 °C, 250 bar pressure, and 0.3 kg/h flow rate of CO2. It was shown that the extraction kinetics of international grape varieties, mutually similar differ significantly from the domestic one. The obtained oil yields were in the range of 8.3% w/w (Gamay) to 10.4% w/w (Pinot Noir) for the international varieties and 5.0% w/w for the domestic variety. The mathematical model “Sovova” was applied to define transport parameters regulating the oil mass transfer inside the seed particles and determine the agreement between experimental and model curves. The interpretation of results took into account the differences of grade seed morphologies (outer surfaces and inner layers) which was investigated by SEM analysis.
AB  - U ovom radu je ekstrakcija natkritičnim ugljen-dioksidom primenjena za dobijanje ulja iz
semenki crvenih sorti grožđa koje su najzastupljenije u Republici Srbiji, od kojih je sorta Prokupac
autohtona, a ostale sorte su internacionalne. Ekstrakcija je izvedena na temperaturi od 50 °C,
pritisku od 250 bar i protoku od 0,3 kg CO2 /h. Pokazano je da je kinetika ekstrakcije slična za
internacionalne sorte grožđa, a da se značajno razlikuje od kinetike ekstrakcije ulja iz autohtone
sorte Prokupac. Prinosi ulja su se kod internacionalnih sorti grožđa kretali od 8,3% (Game) do
10,4% w/w (Pinot Noir), dok je kod domaće sorte Prokupac ostvaren prinos od 4,96% w/w. Za
definisanje parametara ekstrakcije koji regulišu transport mase unutar čestica semenki primenjen
je matematički model “Sovova”. Snimanje unutrašnje i spoljašnje morfologije semenki SEM
metodom je korišćeno za interpretaciju rezultata dobijenih primenom matematičkog modela.
PB  - University of Niš, Serbia
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters
T1  - Ekstrakcija ulja iz semenki crvenih sorti grožđa natkritičnim CO2. Prinosi i parametri ekstrakcije
EP  - 56
IS  - 1
SP  - 45
VL  - 19
DO  - 10.2298/FUPCT2101045M
ER  - 

@article{
author = "Malićanin, Marko and Milanović, Jelena and Žižović, Irena and Ivanović, Jasna and Milovanović, Stoja and Rakić, Vesna",
year = "2021",
abstract = "In this work, the extraction by supercritical carbon dioxide of grapeseed oil from five red grape varieties was investigated. Apart from an indigenous variety Prokupac, as the domestic, and Merlot and Cabernet Sauvignon, as international grape varieties the most represented in the Republic of Serbia, Pinot Noir and Gamay were studied as well. Extraction conditions were: temperature of 50 °C, 250 bar pressure, and 0.3 kg/h flow rate of CO2. It was shown that the extraction kinetics of international grape varieties, mutually similar differ significantly from the domestic one. The obtained oil yields were in the range of 8.3% w/w (Gamay) to 10.4% w/w (Pinot Noir) for the international varieties and 5.0% w/w for the domestic variety. The mathematical model “Sovova” was applied to define transport parameters regulating the oil mass transfer inside the seed particles and determine the agreement between experimental and model curves. The interpretation of results took into account the differences of grade seed morphologies (outer surfaces and inner layers) which was investigated by SEM analysis., U ovom radu je ekstrakcija natkritičnim ugljen-dioksidom primenjena za dobijanje ulja iz
semenki crvenih sorti grožđa koje su najzastupljenije u Republici Srbiji, od kojih je sorta Prokupac
autohtona, a ostale sorte su internacionalne. Ekstrakcija je izvedena na temperaturi od 50 °C,
pritisku od 250 bar i protoku od 0,3 kg CO2 /h. Pokazano je da je kinetika ekstrakcije slična za
internacionalne sorte grožđa, a da se značajno razlikuje od kinetike ekstrakcije ulja iz autohtone
sorte Prokupac. Prinosi ulja su se kod internacionalnih sorti grožđa kretali od 8,3% (Game) do
10,4% w/w (Pinot Noir), dok je kod domaće sorte Prokupac ostvaren prinos od 4,96% w/w. Za
definisanje parametara ekstrakcije koji regulišu transport mase unutar čestica semenki primenjen
je matematički model “Sovova”. Snimanje unutrašnje i spoljašnje morfologije semenki SEM
metodom je korišćeno za interpretaciju rezultata dobijenih primenom matematičkog modela.",
publisher = "University of Niš, Serbia",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters, Ekstrakcija ulja iz semenki crvenih sorti grožđa natkritičnim CO2. Prinosi i parametri ekstrakcije",
pages = "56-45",
number = "1",
volume = "19",
doi = "10.2298/FUPCT2101045M"
}

Malićanin, M., Milanović, J., Žižović, I., Ivanović, J., Milovanović, S.,& Rakić, V.. (2021). SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters. in Facta Universitatis, Series: Physics, Chemistry and Technology
University of Niš, Serbia., 19(1), 45-56.
https://doi.org/10.2298/FUPCT2101045M

Malićanin M, Milanović J, Žižović I, Ivanović J, Milovanović S, Rakić V. SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2021;19(1):45-56.
doi:10.2298/FUPCT2101045M .

Malićanin, Marko, Milanović, Jelena, Žižović, Irena, Ivanović, Jasna, Milovanović, Stoja, Rakić, Vesna, "SupercriticaL CO2 extraction of oils from red grape varieties: yields and extraction parameters" in Facta Universitatis, Series: Physics, Chemistry and Technology, 19, no. 1 (2021):45-56,
https://doi.org/10.2298/FUPCT2101045M . .

TY  - JOUR
AU  - Pajnik, Jelena
AU  - Lukić, Ivana
AU  - Dikić, Jelena
AU  - Ašanin, Jelena
AU  - Gordić, Milan V.
AU  - Mišić, Dušan
AU  - Žižović, Irena
AU  - Korzeniowska, Malgorzata
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4442
AB  - In the present study, supercritical solvent impregnation (SSI) has been applied to incorporate thymol into bio-composite polymers as a potential active packaging material. Thymol, a natural component with a proven antimicrobial activity, was successfully impregnated into starch-chitosan (SC) and starch-chitosan-zeolite (SCZ) films using supercritical carbon dioxide (scCO(2)) as a solvent. Experiments were performed at 35 degrees C, pressures of 15.5 and 30 MPa, and an impregnation time in the range of 4-24 h. The highest impregnation yields of SC films with starch to chitosan mass ratios of 1:1 and 1:2 were 10.80% and 6.48%, respectively. The addition of natural zeolite (15-60%) significantly increased the loading capacity of films enabling thymol incorporation in a quantity of 16.7-27.3%. FTIR and SEM analyses were applied for the characterization of the films. Mechanical properties and water vapor permeability of films before and after the impregnation were tested as well. Thymol release kinetics in deionized water was followed and modeled by the Korsmeyer-Peppas and Weibull model. SCZ films with thymol loading of approximately 24% exhibited strong antibacterial activity against E. coli and methicillin-resistant Staphylococcus (S.) aureus (MRSA).
PB  - MDPI, Basel
T2  - Molecules
T1  - Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties
IS  - 20
VL  - 25
DO  - 10.3390/molecules25204717
ER  - 

@article{
author = "Pajnik, Jelena and Lukić, Ivana and Dikić, Jelena and Ašanin, Jelena and Gordić, Milan V. and Mišić, Dušan and Žižović, Irena and Korzeniowska, Malgorzata",
year = "2020",
abstract = "In the present study, supercritical solvent impregnation (SSI) has been applied to incorporate thymol into bio-composite polymers as a potential active packaging material. Thymol, a natural component with a proven antimicrobial activity, was successfully impregnated into starch-chitosan (SC) and starch-chitosan-zeolite (SCZ) films using supercritical carbon dioxide (scCO(2)) as a solvent. Experiments were performed at 35 degrees C, pressures of 15.5 and 30 MPa, and an impregnation time in the range of 4-24 h. The highest impregnation yields of SC films with starch to chitosan mass ratios of 1:1 and 1:2 were 10.80% and 6.48%, respectively. The addition of natural zeolite (15-60%) significantly increased the loading capacity of films enabling thymol incorporation in a quantity of 16.7-27.3%. FTIR and SEM analyses were applied for the characterization of the films. Mechanical properties and water vapor permeability of films before and after the impregnation were tested as well. Thymol release kinetics in deionized water was followed and modeled by the Korsmeyer-Peppas and Weibull model. SCZ films with thymol loading of approximately 24% exhibited strong antibacterial activity against E. coli and methicillin-resistant Staphylococcus (S.) aureus (MRSA).",
publisher = "MDPI, Basel",
journal = "Molecules",
title = "Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties",
number = "20",
volume = "25",
doi = "10.3390/molecules25204717"
}

Pajnik, J., Lukić, I., Dikić, J., Ašanin, J., Gordić, M. V., Mišić, D., Žižović, I.,& Korzeniowska, M.. (2020). Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties. in Molecules
MDPI, Basel., 25(20).
https://doi.org/10.3390/molecules25204717

Pajnik J, Lukić I, Dikić J, Ašanin J, Gordić MV, Mišić D, Žižović I, Korzeniowska M. Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties. in Molecules. 2020;25(20).
doi:10.3390/molecules25204717 .

Pajnik, Jelena, Lukić, Ivana, Dikić, Jelena, Ašanin, Jelena, Gordić, Milan V., Mišić, Dušan, Žižović, Irena, Korzeniowska, Malgorzata, "Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties" in Molecules, 25, no. 20 (2020),
https://doi.org/10.3390/molecules25204717 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Đuriš, Jelena
AU  - Dapčević, Aleksandra
AU  - Medarević, Đorđe
AU  - Ibrić, Svetlana
AU  - Žižović, Irena
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4074
AB  - The present work is aimed towards designing advanced materials by means of sustainable processes. In that sense, the utilization of supercritical CO2 (scCO(2)) for processing of pharmaceutical polymers (Soluplus (R), Eudragit (R), and hydroxypropyl methylcellulose acetate succinate), alone and with an addition of cardiovascular drug Carvedilol, was explored. Employed single-step static scCO(2) process (pressure of 30 MPa and temperature of 100 degrees C for 2 h) enabled fabrication of solvent-free polymeric foams and Carvedilol solid dispersions with controlled microstructure and average pore diameter of 101-257 pm suitable for application in the pharmaceutical industry. ScCO2 did not remain in the foams after processing or affected the polymer composition, while Carvedilol formed hydrogen bonds with the polymers. Carvedilol was molecularly dispersed in the fabricated solid dispersions and its transition from the crystalline to amorphous form was complete. Korsmeyer-Peppas model was successfully used for the mathematical description of Carvedilol dissolution from solid dispersions. The dissolution rate of Carvedilol in acidic medium was significantly enhanced by its dispersion in tested polymers using the proposed high-pressure method.
PB  - Elsevier Sci Ltd, Oxford
T2  - Polymer Testing
T1  - Soluplus (R), Eudragit (R), HPMC-AS foams and solid dispersions for enhancement of Carvedilol dissolution rate prepared by a supercritical CO2 process
EP  - 64
SP  - 54
VL  - 76
DO  - 10.1016/j.polymertesting.2019.03.001
ER  - 

@article{
author = "Milovanović, Stoja and Đuriš, Jelena and Dapčević, Aleksandra and Medarević, Đorđe and Ibrić, Svetlana and Žižović, Irena",
year = "2019",
abstract = "The present work is aimed towards designing advanced materials by means of sustainable processes. In that sense, the utilization of supercritical CO2 (scCO(2)) for processing of pharmaceutical polymers (Soluplus (R), Eudragit (R), and hydroxypropyl methylcellulose acetate succinate), alone and with an addition of cardiovascular drug Carvedilol, was explored. Employed single-step static scCO(2) process (pressure of 30 MPa and temperature of 100 degrees C for 2 h) enabled fabrication of solvent-free polymeric foams and Carvedilol solid dispersions with controlled microstructure and average pore diameter of 101-257 pm suitable for application in the pharmaceutical industry. ScCO2 did not remain in the foams after processing or affected the polymer composition, while Carvedilol formed hydrogen bonds with the polymers. Carvedilol was molecularly dispersed in the fabricated solid dispersions and its transition from the crystalline to amorphous form was complete. Korsmeyer-Peppas model was successfully used for the mathematical description of Carvedilol dissolution from solid dispersions. The dissolution rate of Carvedilol in acidic medium was significantly enhanced by its dispersion in tested polymers using the proposed high-pressure method.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Testing",
title = "Soluplus (R), Eudragit (R), HPMC-AS foams and solid dispersions for enhancement of Carvedilol dissolution rate prepared by a supercritical CO2 process",
pages = "64-54",
volume = "76",
doi = "10.1016/j.polymertesting.2019.03.001"
}

Milovanović, S., Đuriš, J., Dapčević, A., Medarević, Đ., Ibrić, S.,& Žižović, I.. (2019). Soluplus (R), Eudragit (R), HPMC-AS foams and solid dispersions for enhancement of Carvedilol dissolution rate prepared by a supercritical CO2 process. in Polymer Testing
Elsevier Sci Ltd, Oxford., 76, 54-64.
https://doi.org/10.1016/j.polymertesting.2019.03.001

Milovanović S, Đuriš J, Dapčević A, Medarević Đ, Ibrić S, Žižović I. Soluplus (R), Eudragit (R), HPMC-AS foams and solid dispersions for enhancement of Carvedilol dissolution rate prepared by a supercritical CO2 process. in Polymer Testing. 2019;76:54-64.
doi:10.1016/j.polymertesting.2019.03.001 .

Milovanović, Stoja, Đuriš, Jelena, Dapčević, Aleksandra, Medarević, Đorđe, Ibrić, Svetlana, Žižović, Irena, "Soluplus (R), Eudragit (R), HPMC-AS foams and solid dispersions for enhancement of Carvedilol dissolution rate prepared by a supercritical CO2 process" in Polymer Testing, 76 (2019):54-64,
https://doi.org/10.1016/j.polymertesting.2019.03.001 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Mraković, Ana
AU  - Kuska, Robert
AU  - Žižović, Irena
AU  - Frerich, Sulamith
AU  - Ivanović, Jasna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4173
AB  - Amorphous, medical grade poly(D,L-lactic acid) (PLA) and poly(D,L-lactic-co-glycolic acid) (PLGA) were used to develop systems for controlled release of a natural bioactive substance - thymol. Supercritical carbon dioxide (scCO(2)) was successfully used both as an impregnation medium for thymol incorporation into the polymer matrix and a foaming agent in a single-step batch process. Impregnation of samples using low to moderate scCO(2) densities (273 kg/m(3) and 630 kg/m(3)) and short processing times (2 h and 4 h) enabled thymol loading of 0.920/0-6.62% and formation of microcellular foams upon system depressurization. Thymol effect on structural and thermal properties on foamed samples was proven by FTIR and DSC. The effect of CO2 under elevated pressure on the neat polymers was analysed by high pressure DSC. Foaming of polymers with lower molecular weight by CO2 of higher density yielded foams with smaller pores. All tested foams released thymol in a controlled manner in phosphate buffered saline (PBS) at 37 degrees C within 3 to 6 weeks. Higher loading and lower cell density favoured thymol release rate, while its concentration in PBS for the tested period depended on foam interaction with the medium. Representative PLGA foam sample with the highest thymol loading (6.62%) showed controlled thymol release within 72 h in mediums having pH values from 1.1 to 7.4.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science & Engineering C-Materials for Biological Applications
T1  - Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release
EP  - 404
SP  - 394
VL  - 99
DO  - 10.1016/j.msec.2019.01.106
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Mraković, Ana and Kuska, Robert and Žižović, Irena and Frerich, Sulamith and Ivanović, Jasna",
year = "2019",
abstract = "Amorphous, medical grade poly(D,L-lactic acid) (PLA) and poly(D,L-lactic-co-glycolic acid) (PLGA) were used to develop systems for controlled release of a natural bioactive substance - thymol. Supercritical carbon dioxide (scCO(2)) was successfully used both as an impregnation medium for thymol incorporation into the polymer matrix and a foaming agent in a single-step batch process. Impregnation of samples using low to moderate scCO(2) densities (273 kg/m(3) and 630 kg/m(3)) and short processing times (2 h and 4 h) enabled thymol loading of 0.920/0-6.62% and formation of microcellular foams upon system depressurization. Thymol effect on structural and thermal properties on foamed samples was proven by FTIR and DSC. The effect of CO2 under elevated pressure on the neat polymers was analysed by high pressure DSC. Foaming of polymers with lower molecular weight by CO2 of higher density yielded foams with smaller pores. All tested foams released thymol in a controlled manner in phosphate buffered saline (PBS) at 37 degrees C within 3 to 6 weeks. Higher loading and lower cell density favoured thymol release rate, while its concentration in PBS for the tested period depended on foam interaction with the medium. Representative PLGA foam sample with the highest thymol loading (6.62%) showed controlled thymol release within 72 h in mediums having pH values from 1.1 to 7.4.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science & Engineering C-Materials for Biological Applications",
title = "Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release",
pages = "404-394",
volume = "99",
doi = "10.1016/j.msec.2019.01.106"
}

Milovanović, S., Marković, D., Mraković, A., Kuska, R., Žižović, I., Frerich, S.,& Ivanović, J.. (2019). Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release. in Materials Science & Engineering C-Materials for Biological Applications
Elsevier Science Bv, Amsterdam., 99, 394-404.
https://doi.org/10.1016/j.msec.2019.01.106

Milovanović S, Marković D, Mraković A, Kuska R, Žižović I, Frerich S, Ivanović J. Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release. in Materials Science & Engineering C-Materials for Biological Applications. 2019;99:394-404.
doi:10.1016/j.msec.2019.01.106 .

Milovanović, Stoja, Marković, Darka, Mraković, Ana, Kuska, Robert, Žižović, Irena, Frerich, Sulamith, Ivanović, Jasna, "Supercritical CO2 - assisted production of PLA and PLGA foams for controlled thymol release" in Materials Science & Engineering C-Materials for Biological Applications, 99 (2019):394-404,
https://doi.org/10.1016/j.msec.2019.01.106 . .

TY  - JOUR
AU  - Žižović, Irena
AU  - Senerović, Lidija
AU  - Morić, Ivana
AU  - Adamović, Tijana
AU  - Jovanović, Milena
AU  - Kalagasidis Krušić, Melina
AU  - Mišić, Dušan
AU  - Stojanović, Dušica
AU  - Milovanović, Stoja
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3923
AB  - This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 degrees C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus
EP  - 20
SP  - 11
VL  - 140
DO  - 10.1016/j.supflu.2018.05.025
ER  - 

@article{
author = "Žižović, Irena and Senerović, Lidija and Morić, Ivana and Adamović, Tijana and Jovanović, Milena and Kalagasidis Krušić, Melina and Mišić, Dušan and Stojanović, Dušica and Milovanović, Stoja",
year = "2018",
abstract = "This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 degrees C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus",
pages = "20-11",
volume = "140",
doi = "10.1016/j.supflu.2018.05.025"
}

Žižović, I., Senerović, L., Morić, I., Adamović, T., Jovanović, M., Kalagasidis Krušić, M., Mišić, D., Stojanović, D.,& Milovanović, S.. (2018). Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 140, 11-20.
https://doi.org/10.1016/j.supflu.2018.05.025

Žižović I, Senerović L, Morić I, Adamović T, Jovanović M, Kalagasidis Krušić M, Mišić D, Stojanović D, Milovanović S. Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus. in Journal of Supercritical Fluids. 2018;140:11-20.
doi:10.1016/j.supflu.2018.05.025 .

Žižović, Irena, Senerović, Lidija, Morić, Ivana, Adamović, Tijana, Jovanović, Milena, Kalagasidis Krušić, Melina, Mišić, Dušan, Stojanović, Dušica, Milovanović, Stoja, "Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus" in Journal of Supercritical Fluids, 140 (2018):11-20,
https://doi.org/10.1016/j.supflu.2018.05.025 . .

TY  - JOUR
AU  - Terzić, Ivan
AU  - Ivanović, Jasna
AU  - Žižović, Irena
AU  - Lučić-Škorić, Marija
AU  - Milosavljević, Nedeljko
AU  - Milašinović, Nikola
AU  - Kalagasidis Krušić, Melina
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3946
AB  - Supercritical carbon dioxide (scCO(2)) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO(2) to obtain xero- and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO(2) drying at 11 MPa and 45 degrees C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO(2) at 10 MPa and 35 degrees C. In vitro studies of swelling in PBS at 37 degrees C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG. SCI., 58:2192-2199, 2018.
PB  - Wiley, Hoboken
T2  - Polymer Engineering and Science
T1  - A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol
EP  - 2199
IS  - 12
SP  - 2192
VL  - 58
DO  - 10.1002/pen.24834
ER  - 

@article{
author = "Terzić, Ivan and Ivanović, Jasna and Žižović, Irena and Lučić-Škorić, Marija and Milosavljević, Nedeljko and Milašinović, Nikola and Kalagasidis Krušić, Melina",
year = "2018",
abstract = "Supercritical carbon dioxide (scCO(2)) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO(2) to obtain xero- and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO(2) drying at 11 MPa and 45 degrees C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO(2) at 10 MPa and 35 degrees C. In vitro studies of swelling in PBS at 37 degrees C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG. SCI., 58:2192-2199, 2018.",
publisher = "Wiley, Hoboken",
journal = "Polymer Engineering and Science",
title = "A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol",
pages = "2199-2192",
number = "12",
volume = "58",
doi = "10.1002/pen.24834"
}

Terzić, I., Ivanović, J., Žižović, I., Lučić-Škorić, M., Milosavljević, N., Milašinović, N.,& Kalagasidis Krušić, M.. (2018). A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol. in Polymer Engineering and Science
Wiley, Hoboken., 58(12), 2192-2199.
https://doi.org/10.1002/pen.24834

Terzić I, Ivanović J, Žižović I, Lučić-Škorić M, Milosavljević N, Milašinović N, Kalagasidis Krušić M. A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol. in Polymer Engineering and Science. 2018;58(12):2192-2199.
doi:10.1002/pen.24834 .

Terzić, Ivan, Ivanović, Jasna, Žižović, Irena, Lučić-Škorić, Marija, Milosavljević, Nedeljko, Milašinović, Nikola, Kalagasidis Krušić, Melina, "A novel chitosan gels: Supercritical CO2 drying and impregnation with thymol" in Polymer Engineering and Science, 58, no. 12 (2018):2192-2199,
https://doi.org/10.1002/pen.24834 . .

TY  - JOUR
AU  - Pajnik, Jelena
AU  - Radetić, Maja
AU  - Stojanović, Dušica
AU  - Janković-Častvan, Ivona
AU  - Tadić, Vanja
AU  - Stanković, Miroslav
AU  - Jovanović, Dušan M.
AU  - Žižović, Irena
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4035
AB  - This study discusses the possibility of supercritical solvent impregnation of polypropylene and polyamide fabrics as well as cellulose acetate in the form of beads and films with pyrethrum extract in order to fabricate functionalized materials with repellent properties. Impregnation experiments were performed at temperature of 40 degrees C and pressures of 10 and 20 MPa in supercritical carbon dioxide. The time of impregnation was varied from 0.5 to 18 h. Loadings of pyrethrum extract into polypropylene fabrics and cellulose acetate films higher than 30% were attainable at 10 MPa. In the case of polyamide fabrics and cellulose acetate beads, the pressure of 20 MPa was needed for obtaining the loadings higher than 11%. Pyrethrum extract release study revealed different capabilities of the tested materials for the repellent release, implying a variety of their possible applications. The impregnated solids were characterized by SEM, DSC, FTIR, Mercury intrusion porosimetry analyses and HPLC analyses.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Functionalization of polypropylene, polyamide and cellulose acetate materials with pyrethrum extract as a natural repellent in supercritical carbon dioxide
EP  - 81
SP  - 70
VL  - 136
DO  - 10.1016/j.supflu.2018.02.014
ER  - 

@article{
author = "Pajnik, Jelena and Radetić, Maja and Stojanović, Dušica and Janković-Častvan, Ivona and Tadić, Vanja and Stanković, Miroslav and Jovanović, Dušan M. and Žižović, Irena",
year = "2018",
abstract = "This study discusses the possibility of supercritical solvent impregnation of polypropylene and polyamide fabrics as well as cellulose acetate in the form of beads and films with pyrethrum extract in order to fabricate functionalized materials with repellent properties. Impregnation experiments were performed at temperature of 40 degrees C and pressures of 10 and 20 MPa in supercritical carbon dioxide. The time of impregnation was varied from 0.5 to 18 h. Loadings of pyrethrum extract into polypropylene fabrics and cellulose acetate films higher than 30% were attainable at 10 MPa. In the case of polyamide fabrics and cellulose acetate beads, the pressure of 20 MPa was needed for obtaining the loadings higher than 11%. Pyrethrum extract release study revealed different capabilities of the tested materials for the repellent release, implying a variety of their possible applications. The impregnated solids were characterized by SEM, DSC, FTIR, Mercury intrusion porosimetry analyses and HPLC analyses.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Functionalization of polypropylene, polyamide and cellulose acetate materials with pyrethrum extract as a natural repellent in supercritical carbon dioxide",
pages = "81-70",
volume = "136",
doi = "10.1016/j.supflu.2018.02.014"
}

Pajnik, J., Radetić, M., Stojanović, D., Janković-Častvan, I., Tadić, V., Stanković, M., Jovanović, D. M.,& Žižović, I.. (2018). Functionalization of polypropylene, polyamide and cellulose acetate materials with pyrethrum extract as a natural repellent in supercritical carbon dioxide. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 136, 70-81.
https://doi.org/10.1016/j.supflu.2018.02.014

Pajnik J, Radetić M, Stojanović D, Janković-Častvan I, Tadić V, Stanković M, Jovanović DM, Žižović I. Functionalization of polypropylene, polyamide and cellulose acetate materials with pyrethrum extract as a natural repellent in supercritical carbon dioxide. in Journal of Supercritical Fluids. 2018;136:70-81.
doi:10.1016/j.supflu.2018.02.014 .

Pajnik, Jelena, Radetić, Maja, Stojanović, Dušica, Janković-Častvan, Ivona, Tadić, Vanja, Stanković, Miroslav, Jovanović, Dušan M., Žižović, Irena, "Functionalization of polypropylene, polyamide and cellulose acetate materials with pyrethrum extract as a natural repellent in supercritical carbon dioxide" in Journal of Supercritical Fluids, 136 (2018):70-81,
https://doi.org/10.1016/j.supflu.2018.02.014 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Tadić, Vanja
AU  - Ivanović, Jasna
AU  - Radmanović, Tanja
AU  - Milovanović, Stoja
AU  - Stanković, Milica
AU  - Žižović, Irena
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3867
AB  - Supercritical CO2 extraction of Helichrysum italicum and impregnation of starch xerogels with the extract by using an integrated scCO(2) extraction and impregnation process were performed at 350 bar and 40 degrees C in order to produce biomaterials for possible oral intake of the extract. Xerogels produced by air-drying of acetogels and alcogels were used as carriers in the supercritical impregnation process. The effect of ethanol as a co-solvent, contact time, plant material/carrier mass ratio and xerogel preparation on the impregnation loading was studied. The highest impregnation loading (1.261 +/- 0.22%) was achieved after 5 h impregnation of the xerogel obtained from alcogel using pure scCO(2) and plant material/carrier mass ratio of 10. Chemical analysis of the extracts showed that the addition of ethanol as co-solvent had a positive effect on scCO(2) selectivity to terpene fraction and total flavonoids, while it lowered the total phenolic content. Despite the difference in chemical composition, both extracts expressed similar antioxidant activity according to the DPPH and FRAP methods. The integrated process was shown to be a feasible method for isolation and incorporation of bioactive components of H italicum into starch xerogels.
PB  - Savez hemijskih inženjera, Beograd
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel
EP  - 200
IS  - 2
SP  - 191
VL  - 24
DO  - 10.2298/CICEQ170223031M
ER  - 

@article{
author = "Maksimović, Svetolik and Tadić, Vanja and Ivanović, Jasna and Radmanović, Tanja and Milovanović, Stoja and Stanković, Milica and Žižović, Irena",
year = "2018",
abstract = "Supercritical CO2 extraction of Helichrysum italicum and impregnation of starch xerogels with the extract by using an integrated scCO(2) extraction and impregnation process were performed at 350 bar and 40 degrees C in order to produce biomaterials for possible oral intake of the extract. Xerogels produced by air-drying of acetogels and alcogels were used as carriers in the supercritical impregnation process. The effect of ethanol as a co-solvent, contact time, plant material/carrier mass ratio and xerogel preparation on the impregnation loading was studied. The highest impregnation loading (1.261 +/- 0.22%) was achieved after 5 h impregnation of the xerogel obtained from alcogel using pure scCO(2) and plant material/carrier mass ratio of 10. Chemical analysis of the extracts showed that the addition of ethanol as co-solvent had a positive effect on scCO(2) selectivity to terpene fraction and total flavonoids, while it lowered the total phenolic content. Despite the difference in chemical composition, both extracts expressed similar antioxidant activity according to the DPPH and FRAP methods. The integrated process was shown to be a feasible method for isolation and incorporation of bioactive components of H italicum into starch xerogels.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel",
pages = "200-191",
number = "2",
volume = "24",
doi = "10.2298/CICEQ170223031M"
}

Maksimović, S., Tadić, V., Ivanović, J., Radmanović, T., Milovanović, S., Stanković, M.,& Žižović, I.. (2018). Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel. in Chemical Industry & Chemical Engineering Quarterly
Savez hemijskih inženjera, Beograd., 24(2), 191-200.
https://doi.org/10.2298/CICEQ170223031M

Maksimović S, Tadić V, Ivanović J, Radmanović T, Milovanović S, Stanković M, Žižović I. Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel. in Chemical Industry & Chemical Engineering Quarterly. 2018;24(2):191-200.
doi:10.2298/CICEQ170223031M .

Maksimović, Svetolik, Tadić, Vanja, Ivanović, Jasna, Radmanović, Tanja, Milovanović, Stoja, Stanković, Milica, Žižović, Irena, "Utilization of the integrated process of supercritical extraction and impregnation for incorporation of helichrysum italicum extract into corn starch xerogel" in Chemical Industry & Chemical Engineering Quarterly, 24, no. 2 (2018):191-200,
https://doi.org/10.2298/CICEQ170223031M . .

TY  - JOUR
AU  - Marković, Darka
AU  - Milovanović, Stoja
AU  - Radoicić, Marija
AU  - Radovanović, Željko
AU  - Žižović, Irena
AU  - Šaponjić, Zoran
AU  - Radetić, Maja
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3904
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(epsilon-caprolactone) beads and foams
EP  - S381
IS  - 12
SP  - S380
VL  - 83
UR  - https://hdl.handle.net/21.15107/rcub_technorep_3904
ER  - 

@article{
author = "Marković, Darka and Milovanović, Stoja and Radoicić, Marija and Radovanović, Željko and Žižović, Irena and Šaponjić, Zoran and Radetić, Maja",
year = "2018",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(epsilon-caprolactone) beads and foams",
pages = "S381-S380",
number = "12",
volume = "83",
url = "https://hdl.handle.net/21.15107/rcub_technorep_3904"
}

Marković, D., Milovanović, S., Radoicić, M., Radovanović, Ž., Žižović, I., Šaponjić, Z.,& Radetić, M.. (2018). Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(epsilon-caprolactone) beads and foams. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 83(12), S380-S381.
https://hdl.handle.net/21.15107/rcub_technorep_3904

Marković D, Milovanović S, Radoicić M, Radovanović Ž, Žižović I, Šaponjić Z, Radetić M. Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(epsilon-caprolactone) beads and foams. in Journal of the Serbian Chemical Society. 2018;83(12):S380-S381.
https://hdl.handle.net/21.15107/rcub_technorep_3904 .

Marković, Darka, Milovanović, Stoja, Radoicić, Marija, Radovanović, Željko, Žižović, Irena, Šaponjić, Zoran, Radetić, Maja, "Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(epsilon-caprolactone) beads and foams" in Journal of the Serbian Chemical Society, 83, no. 12 (2018):S380-S381,
https://hdl.handle.net/21.15107/rcub_technorep_3904 .

TY  - JOUR
AU  - Marković, Darka
AU  - Milovanović, Stoja
AU  - De Clerck, Karen
AU  - Žižović, Irena
AU  - Stojanović, Dušica
AU  - Radetić, Maja
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3889
AB  - This study discusses the potential of high pressure (supercritical and liquid) CO2 impregnation to load electrospun polyamide nanofibers with thymol as an antimicrobial agent. The influence of selected pressures and temperatures on the thymol impregnation yield has been evaluated. High pressure impregnation provided superior thymol impregnation yields (up to similar to 60%) on nanofibers compared to conventional immersion methods (similar to 2%). The presence of thymol in impregnated samples was confirmed by FT-IR analysis. FESEM analysis revealed that impregnation with thymol resulted in a swelling of the nanofibers. The nanofiber morphological changes strongly depended on the thymol impregnation yield. Nanofibers impregnated with thymol using high pressure CO2 ensured excellent antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacterium S. aureus and fungus C. albicans. In addition, the Higuchi release model well fitted the thymol release studies.
PB  - Elsevier Sci Ltd, Oxford
T2  - Journal of CO2 Utilization
T1  - Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol
EP  - 27
SP  - 19
VL  - 26
DO  - 10.1016/j.jcou.2018.04.019
ER  - 

@article{
author = "Marković, Darka and Milovanović, Stoja and De Clerck, Karen and Žižović, Irena and Stojanović, Dušica and Radetić, Maja",
year = "2018",
abstract = "This study discusses the potential of high pressure (supercritical and liquid) CO2 impregnation to load electrospun polyamide nanofibers with thymol as an antimicrobial agent. The influence of selected pressures and temperatures on the thymol impregnation yield has been evaluated. High pressure impregnation provided superior thymol impregnation yields (up to similar to 60%) on nanofibers compared to conventional immersion methods (similar to 2%). The presence of thymol in impregnated samples was confirmed by FT-IR analysis. FESEM analysis revealed that impregnation with thymol resulted in a swelling of the nanofibers. The nanofiber morphological changes strongly depended on the thymol impregnation yield. Nanofibers impregnated with thymol using high pressure CO2 ensured excellent antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacterium S. aureus and fungus C. albicans. In addition, the Higuchi release model well fitted the thymol release studies.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Journal of CO2 Utilization",
title = "Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol",
pages = "27-19",
volume = "26",
doi = "10.1016/j.jcou.2018.04.019"
}

Marković, D., Milovanović, S., De Clerck, K., Žižović, I., Stojanović, D.,& Radetić, M.. (2018). Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol. in Journal of CO2 Utilization
Elsevier Sci Ltd, Oxford., 26, 19-27.
https://doi.org/10.1016/j.jcou.2018.04.019

Marković D, Milovanović S, De Clerck K, Žižović I, Stojanović D, Radetić M. Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol. in Journal of CO2 Utilization. 2018;26:19-27.
doi:10.1016/j.jcou.2018.04.019 .

Marković, Darka, Milovanović, Stoja, De Clerck, Karen, Žižović, Irena, Stojanović, Dušica, Radetić, Maja, "Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol" in Journal of CO2 Utilization, 26 (2018):19-27,
https://doi.org/10.1016/j.jcou.2018.04.019 . .

TY  - JOUR
AU  - Marković, Darka
AU  - Milovanović, Stoja
AU  - Radoičić, M.
AU  - Radovanović, Željko
AU  - Žižović, Irena
AU  - Šaponjić, Zoran
AU  - Radetić, Maja
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3789
AB  - This study discusses the possibility of immobilization of colloidal TiO2 nanoparticles (NPs) onto poly(ε-caprolactone) (PCL) beads and foams that could be utilized for the removal of textile dyes from water by photodegradation. PCL foams were fabricated by environmentally friendly treatment of PCL beads in supercritical carbon dioxide. PCL beads and foams loaded with colloidal TiO2 NPs were used as photocatalysts for the removal of the textile dyes C.I. Acid Orange 7 and C.I. Basic Yellow 28 from aqueous solutions (10 mg L-1) under illumination that simulated sunlight. Unlike the PCL beads, the PCL foams provided complete discoloration of the dye solution within 24 h of illumination. The PCL foams also exhibited excellent floatability that was maintained for more than four weeks. Additionally, their photocatalytic activity was preserved within three repeated photodegradation cycles, indicating that the floating photocatalyst provided superior photocatalytic activity compared to the non-floating PCL beads.
PB  - Serbian Chemical Society, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(ε-caprolactone) beads and foams
EP  - 1389
IS  - 12
SP  - 1379
VL  - 83
DO  - 10.2298/JSC180913089M
ER  - 

@article{
author = "Marković, Darka and Milovanović, Stoja and Radoičić, M. and Radovanović, Željko and Žižović, Irena and Šaponjić, Zoran and Radetić, Maja",
year = "2018",
abstract = "This study discusses the possibility of immobilization of colloidal TiO2 nanoparticles (NPs) onto poly(ε-caprolactone) (PCL) beads and foams that could be utilized for the removal of textile dyes from water by photodegradation. PCL foams were fabricated by environmentally friendly treatment of PCL beads in supercritical carbon dioxide. PCL beads and foams loaded with colloidal TiO2 NPs were used as photocatalysts for the removal of the textile dyes C.I. Acid Orange 7 and C.I. Basic Yellow 28 from aqueous solutions (10 mg L-1) under illumination that simulated sunlight. Unlike the PCL beads, the PCL foams provided complete discoloration of the dye solution within 24 h of illumination. The PCL foams also exhibited excellent floatability that was maintained for more than four weeks. Additionally, their photocatalytic activity was preserved within three repeated photodegradation cycles, indicating that the floating photocatalyst provided superior photocatalytic activity compared to the non-floating PCL beads.",
publisher = "Serbian Chemical Society, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(ε-caprolactone) beads and foams",
pages = "1389-1379",
number = "12",
volume = "83",
doi = "10.2298/JSC180913089M"
}

Marković, D., Milovanović, S., Radoičić, M., Radovanović, Ž., Žižović, I., Šaponjić, Z.,& Radetić, M.. (2018). Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(ε-caprolactone) beads and foams. in Journal of the Serbian Chemical Society
Serbian Chemical Society, Belgrade., 83(12), 1379-1389.
https://doi.org/10.2298/JSC180913089M

Marković D, Milovanović S, Radoičić M, Radovanović Ž, Žižović I, Šaponjić Z, Radetić M. Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(ε-caprolactone) beads and foams. in Journal of the Serbian Chemical Society. 2018;83(12):1379-1389.
doi:10.2298/JSC180913089M .

Marković, Darka, Milovanović, Stoja, Radoičić, M., Radovanović, Željko, Žižović, Irena, Šaponjić, Zoran, Radetić, Maja, "Removal of textile dyes from water by TiO2 nanoparticles immobilized on poly(ε-caprolactone) beads and foams" in Journal of the Serbian Chemical Society, 83, no. 12 (2018):1379-1389,
https://doi.org/10.2298/JSC180913089M . .

TY  - JOUR
AU  - Adamović, Tijana
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Žižović, Irena
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3817
AB  - Cellulose acetate films were impregnated with carvacrol using supercritical carbon dioxide. The supercritical impregnation process, conducted in a static regime at pressure of 21 MPa and temperature of 50°C, was optimized by variation in the processing time (30 and 120 min) and decompression rate (from 0.3 MPa/min to 36 MPa/min). Characterization of the obtained cellulose acetate films was performed by Atomic Force Microscopy and Differential Scanning Calorimetry. Effects of glycerol and carvacrol on the properties of the films were discussed. Release kinetics from the cellulose acetate film with 31.4% of carvacrol was investigated in a physiological saline solution. In addition, the Higuchi and Korsmeyer-Peppas release models fitted the carvacrol release curve well. Obtained cellulose acetate films impregnated with carvacrol can be of interest for the application in medicine as wound dressings considering their biocompatibility and biodegradability as well as their potential antimicrobial activity or in the food industry as an active food packaging.
AB  - Filmovi acetata celuloze su impregnirani karvakrolom pomoću natkritičnog ugljenik(IV)-oksida. Proces natkritične impregnacije, izveden u statičkom režimu na pritisku 21 MPa i temperaturi 50°C, je optimizovan varijacijom procesnog vremena (30 i 120 min) i brzine dekompresije (od 0,3 MPa/min do 36 MPa/min). Karakterizacija dobijenih filmova acetata celuloze je izvedena pomoću mikroskopije atomskih sila i diferencijalne skenirajuće kalorimetrije. Efekat glicerola i karvakrola na karakteristike dobijenih filmova je objašnjen. Otpuštanje karvakrola iz filma koji je ima 31,4% primos impregnacije karvakrola je ispitano u fiziološkom rastvoru. Dodatno, Higuči i Korsmejer-Pepas modeli otpuštanja su dobro fitovali krivu otpuštanja karvakrola. Dobijeni filmovi acetata celuloze impregnirani karvakrolom mogu biti značajni za primenu u medicini za previjanje rana uzimajući u obzir njihovu biokompatibilnost i biodegradabilnost kao i potencijalno antimikrobno dejstvo ili u industriji hrane kao aktivno pakovanje.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Impregnation of cellulose acetate films with carvacrol using supercritical carbon ioxide
T1  - Impregnacija filmova acetata celuloze karvakrolom pomoću natkritičnog ugljenik(IV)-oksida
EP  - 25
IS  - 1
SP  - 19
VL  - 73
DO  - 10.5937/tehnika1801017A
ER  - 

@article{
author = "Adamović, Tijana and Milovanović, Stoja and Marković, Darka and Žižović, Irena",
year = "2018",
abstract = "Cellulose acetate films were impregnated with carvacrol using supercritical carbon dioxide. The supercritical impregnation process, conducted in a static regime at pressure of 21 MPa and temperature of 50°C, was optimized by variation in the processing time (30 and 120 min) and decompression rate (from 0.3 MPa/min to 36 MPa/min). Characterization of the obtained cellulose acetate films was performed by Atomic Force Microscopy and Differential Scanning Calorimetry. Effects of glycerol and carvacrol on the properties of the films were discussed. Release kinetics from the cellulose acetate film with 31.4% of carvacrol was investigated in a physiological saline solution. In addition, the Higuchi and Korsmeyer-Peppas release models fitted the carvacrol release curve well. Obtained cellulose acetate films impregnated with carvacrol can be of interest for the application in medicine as wound dressings considering their biocompatibility and biodegradability as well as their potential antimicrobial activity or in the food industry as an active food packaging., Filmovi acetata celuloze su impregnirani karvakrolom pomoću natkritičnog ugljenik(IV)-oksida. Proces natkritične impregnacije, izveden u statičkom režimu na pritisku 21 MPa i temperaturi 50°C, je optimizovan varijacijom procesnog vremena (30 i 120 min) i brzine dekompresije (od 0,3 MPa/min do 36 MPa/min). Karakterizacija dobijenih filmova acetata celuloze je izvedena pomoću mikroskopije atomskih sila i diferencijalne skenirajuće kalorimetrije. Efekat glicerola i karvakrola na karakteristike dobijenih filmova je objašnjen. Otpuštanje karvakrola iz filma koji je ima 31,4% primos impregnacije karvakrola je ispitano u fiziološkom rastvoru. Dodatno, Higuči i Korsmejer-Pepas modeli otpuštanja su dobro fitovali krivu otpuštanja karvakrola. Dobijeni filmovi acetata celuloze impregnirani karvakrolom mogu biti značajni za primenu u medicini za previjanje rana uzimajući u obzir njihovu biokompatibilnost i biodegradabilnost kao i potencijalno antimikrobno dejstvo ili u industriji hrane kao aktivno pakovanje.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Impregnation of cellulose acetate films with carvacrol using supercritical carbon ioxide, Impregnacija filmova acetata celuloze karvakrolom pomoću natkritičnog ugljenik(IV)-oksida",
pages = "25-19",
number = "1",
volume = "73",
doi = "10.5937/tehnika1801017A"
}

Adamović, T., Milovanović, S., Marković, D.,& Žižović, I.. (2018). Impregnation of cellulose acetate films with carvacrol using supercritical carbon ioxide. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 73(1), 19-25.
https://doi.org/10.5937/tehnika1801017A

Adamović T, Milovanović S, Marković D, Žižović I. Impregnation of cellulose acetate films with carvacrol using supercritical carbon ioxide. in Tehnika. 2018;73(1):19-25.
doi:10.5937/tehnika1801017A .

Adamović, Tijana, Milovanović, Stoja, Marković, Darka, Žižović, Irena, "Impregnation of cellulose acetate films with carvacrol using supercritical carbon ioxide" in Tehnika, 73, no. 1 (2018):19-25,
https://doi.org/10.5937/tehnika1801017A . .

TY  - JOUR
AU  - Marković, Darka
AU  - Milovanović, Stoja
AU  - Radovanović, Željko
AU  - Žižović, Irena
AU  - Šaponjić, Zoran
AU  - Radetić, Maja
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3861
AB  - This study discusses a novel approach for fabrication of floating photocatalyst which can be efficiently exploited for photodegradation of dyes in aqueous solutions. A fabrication of the floating photocatalyst consisted of two steps: transformation of the poly(epsilon-caprolactone) beads (PCLb) into poly(epsilon-caprolactone) foam (PCLf) with porous structure in supercritical carbon-dioxide and subsequent loading of PCLf with TiO2 nanoparticles (NPs). Morphological characterization of the PCLf before and after TiO2 NPs loading was carried out by FESEM. The presence of titanium on the surface and inside the PCLf was detected by EDX. Photocatalytical activity of the floating photocatalyst was investigated in aqueous solution of textile dyes C.I. Acid Orange 7 (AO7) and C.I. Basic Yellow 28 (BY28) which were exposed to lamp that simulates the sun light. In addition to sustainable floatability for a long period of time, developed floating photocatalyst exhibited high rate of photodegradation since the complete discoloration of AO7 and BY28 solutions and photocatalysts alone occurred after 300 and 180 min of illumination, respectively. Its photocatalytic activity was preserved after three repeated photodegradation cycles with unchanged chemical structure that was confirmed by FTIR analysis.
PB  - Korean Fiber Soc, Seoul
T2  - Fibers and Polymers
T1  - Floating Photocatalyst Based on Poly(epsilon-caprolactone) Foam and TiO2 Nanoparticles for Removal of Textile Dyes
EP  - 1227
IS  - 6
SP  - 1219
VL  - 19
DO  - 10.1007/s12221-018-8148-5
ER  - 

@article{
author = "Marković, Darka and Milovanović, Stoja and Radovanović, Željko and Žižović, Irena and Šaponjić, Zoran and Radetić, Maja",
year = "2018",
abstract = "This study discusses a novel approach for fabrication of floating photocatalyst which can be efficiently exploited for photodegradation of dyes in aqueous solutions. A fabrication of the floating photocatalyst consisted of two steps: transformation of the poly(epsilon-caprolactone) beads (PCLb) into poly(epsilon-caprolactone) foam (PCLf) with porous structure in supercritical carbon-dioxide and subsequent loading of PCLf with TiO2 nanoparticles (NPs). Morphological characterization of the PCLf before and after TiO2 NPs loading was carried out by FESEM. The presence of titanium on the surface and inside the PCLf was detected by EDX. Photocatalytical activity of the floating photocatalyst was investigated in aqueous solution of textile dyes C.I. Acid Orange 7 (AO7) and C.I. Basic Yellow 28 (BY28) which were exposed to lamp that simulates the sun light. In addition to sustainable floatability for a long period of time, developed floating photocatalyst exhibited high rate of photodegradation since the complete discoloration of AO7 and BY28 solutions and photocatalysts alone occurred after 300 and 180 min of illumination, respectively. Its photocatalytic activity was preserved after three repeated photodegradation cycles with unchanged chemical structure that was confirmed by FTIR analysis.",
publisher = "Korean Fiber Soc, Seoul",
journal = "Fibers and Polymers",
title = "Floating Photocatalyst Based on Poly(epsilon-caprolactone) Foam and TiO2 Nanoparticles for Removal of Textile Dyes",
pages = "1227-1219",
number = "6",
volume = "19",
doi = "10.1007/s12221-018-8148-5"
}

Marković, D., Milovanović, S., Radovanović, Ž., Žižović, I., Šaponjić, Z.,& Radetić, M.. (2018). Floating Photocatalyst Based on Poly(epsilon-caprolactone) Foam and TiO2 Nanoparticles for Removal of Textile Dyes. in Fibers and Polymers
Korean Fiber Soc, Seoul., 19(6), 1219-1227.
https://doi.org/10.1007/s12221-018-8148-5

Marković D, Milovanović S, Radovanović Ž, Žižović I, Šaponjić Z, Radetić M. Floating Photocatalyst Based on Poly(epsilon-caprolactone) Foam and TiO2 Nanoparticles for Removal of Textile Dyes. in Fibers and Polymers. 2018;19(6):1219-1227.
doi:10.1007/s12221-018-8148-5 .

Marković, Darka, Milovanović, Stoja, Radovanović, Željko, Žižović, Irena, Šaponjić, Zoran, Radetić, Maja, "Floating Photocatalyst Based on Poly(epsilon-caprolactone) Foam and TiO2 Nanoparticles for Removal of Textile Dyes" in Fibers and Polymers, 19, no. 6 (2018):1219-1227,
https://doi.org/10.1007/s12221-018-8148-5 . .

TY  - JOUR
AU  - Pajnik, Jelena
AU  - Stamenić, Marko
AU  - Radetić, Maja
AU  - Tomanović, Snežana
AU  - Sukara, Ratko
AU  - Mihaljica, Darko
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3574
AB  - This study discusses a possibility of cotton fabric impregnation with pyrethrum extract as a tick repellent in supercritical carbon dioxide. A solubility of pyrethrum extract in supercritical carbon dioxide has been determined at 35 and 40 degrees C and pressures ranging from 8 to 20 MPa. The highest solubility of 48.69 kg/m(3) was obtained at temperature of 35 degrees C and pressure of 20 MPa. Density -based equations of Chrastil, Adachi-Lu and del Valle-Aguilera were employed to correlate the experimental data. Based on the solubility data, conditions for the impregnation of cotton fabric were selected. Conditions at 40 degrees C and 8 MPa provided targeted quantities of the impregnated extract of 0.5% and 1% after 1 h and 2 h of the impregnation, respectively. The presence of pyrethrins on the cotton fabric's surface was confirmed by FTIR analysis. Repellent activity of both impregnated cotton fabrics (pyrethrum extract contents of 0.5% and 1%) was proven against ticks.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Impregnation of cotton fabric with pyrethrum extract in supercritical carbon dioxide
EP  - 72
SP  - 66
VL  - 128
DO  - 10.1016/j.supflu.2017.05.006
ER  - 

@article{
author = "Pajnik, Jelena and Stamenić, Marko and Radetić, Maja and Tomanović, Snežana and Sukara, Ratko and Mihaljica, Darko and Žižović, Irena",
year = "2017",
abstract = "This study discusses a possibility of cotton fabric impregnation with pyrethrum extract as a tick repellent in supercritical carbon dioxide. A solubility of pyrethrum extract in supercritical carbon dioxide has been determined at 35 and 40 degrees C and pressures ranging from 8 to 20 MPa. The highest solubility of 48.69 kg/m(3) was obtained at temperature of 35 degrees C and pressure of 20 MPa. Density -based equations of Chrastil, Adachi-Lu and del Valle-Aguilera were employed to correlate the experimental data. Based on the solubility data, conditions for the impregnation of cotton fabric were selected. Conditions at 40 degrees C and 8 MPa provided targeted quantities of the impregnated extract of 0.5% and 1% after 1 h and 2 h of the impregnation, respectively. The presence of pyrethrins on the cotton fabric's surface was confirmed by FTIR analysis. Repellent activity of both impregnated cotton fabrics (pyrethrum extract contents of 0.5% and 1%) was proven against ticks.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Impregnation of cotton fabric with pyrethrum extract in supercritical carbon dioxide",
pages = "72-66",
volume = "128",
doi = "10.1016/j.supflu.2017.05.006"
}

Pajnik, J., Stamenić, M., Radetić, M., Tomanović, S., Sukara, R., Mihaljica, D.,& Žižović, I.. (2017). Impregnation of cotton fabric with pyrethrum extract in supercritical carbon dioxide. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 128, 66-72.
https://doi.org/10.1016/j.supflu.2017.05.006

Pajnik J, Stamenić M, Radetić M, Tomanović S, Sukara R, Mihaljica D, Žižović I. Impregnation of cotton fabric with pyrethrum extract in supercritical carbon dioxide. in Journal of Supercritical Fluids. 2017;128:66-72.
doi:10.1016/j.supflu.2017.05.006 .

Pajnik, Jelena, Stamenić, Marko, Radetić, Maja, Tomanović, Snežana, Sukara, Ratko, Mihaljica, Darko, Žižović, Irena, "Impregnation of cotton fabric with pyrethrum extract in supercritical carbon dioxide" in Journal of Supercritical Fluids, 128 (2017):66-72,
https://doi.org/10.1016/j.supflu.2017.05.006 . .

TY  - CHAP
AU  - Milovanović, Stoja
AU  - Radetić, Maja
AU  - Misić, D.
AU  - Ašanin, Jelena
AU  - Leontijević, V.
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3496
AB  - The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed.
T2  - Cotton Fibres: Characteristics, Uses and Performance
T1  - High pressure modified cotton in wound dressing applications
EP  - 205
SP  - 177
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1463
ER  - 

@inbook{
author = "Milovanović, Stoja and Radetić, Maja and Misić, D. and Ašanin, Jelena and Leontijević, V. and Ivanović, Jasna and Žižović, Irena",
year = "2017",
abstract = "The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed.",
journal = "Cotton Fibres: Characteristics, Uses and Performance",
booktitle = "High pressure modified cotton in wound dressing applications",
pages = "205-177",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1463"
}

Milovanović, S., Radetić, M., Misić, D., Ašanin, J., Leontijević, V., Ivanović, J.,& Žižović, I.. (2017). High pressure modified cotton in wound dressing applications. in Cotton Fibres: Characteristics, Uses and Performance, 177-205.
https://hdl.handle.net/21.15107/rcub_veterinar_1463

Milovanović S, Radetić M, Misić D, Ašanin J, Leontijević V, Ivanović J, Žižović I. High pressure modified cotton in wound dressing applications. in Cotton Fibres: Characteristics, Uses and Performance. 2017;:177-205.
https://hdl.handle.net/21.15107/rcub_veterinar_1463 .

Milovanović, Stoja, Radetić, Maja, Misić, D., Ašanin, Jelena, Leontijević, V., Ivanović, Jasna, Žižović, Irena, "High pressure modified cotton in wound dressing applications" in Cotton Fibres: Characteristics, Uses and Performance (2017):177-205,
https://hdl.handle.net/21.15107/rcub_veterinar_1463 .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Adamović, Tijana
AU  - Aksentijević, Ksenija
AU  - Mišić, Dušan
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3571
AB  - Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 degrees C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.
PB  - Hindawi Ltd, London
T2  - International Journal of Polymer Science
T1  - Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation
VL  - 2017
DO  - 10.1155/2017/8762649
ER  - 

@article{
author = "Milovanović, Stoja and Adamović, Tijana and Aksentijević, Ksenija and Mišić, Dušan and Ivanović, Jasna and Žižović, Irena",
year = "2017",
abstract = "Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 degrees C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.",
publisher = "Hindawi Ltd, London",
journal = "International Journal of Polymer Science",
title = "Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation",
volume = "2017",
doi = "10.1155/2017/8762649"
}

Milovanović, S., Adamović, T., Aksentijević, K., Mišić, D., Ivanović, J.,& Žižović, I.. (2017). Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation. in International Journal of Polymer Science
Hindawi Ltd, London., 2017.
https://doi.org/10.1155/2017/8762649

Milovanović S, Adamović T, Aksentijević K, Mišić D, Ivanović J, Žižović I. Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation. in International Journal of Polymer Science. 2017;2017.
doi:10.1155/2017/8762649 .

Milovanović, Stoja, Adamović, Tijana, Aksentijević, Ksenija, Mišić, Dušan, Ivanović, Jasna, Žižović, Irena, "Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation" in International Journal of Polymer Science, 2017 (2017),
https://doi.org/10.1155/2017/8762649 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Tadić, Vanja
AU  - Skala, Dejan
AU  - Žižović, Irena
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3757
AB  - Helichrysum italicum presents a valuable source of natural bioactive compounds. In this work, a literature review of terpenes, phenolic compounds, and other less common phytochemicals from H. italicum with regard to application of different separation methods is presented. Data including extraction/separation methods and experimental conditions applied, obtained yields, number of identified compounds, content of different compound groups, and analytical techniques applied are shown as corresponding tables. Numerous biological activities of both isolates and individual compounds are emphasized. In addition, the data reported are discussed, and the directions for further investigations are proposed.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Separation of phytochemicals from Helichrysum italicum: An analysis of different isolation techniques and biological activity of prepared extracts
EP  - 28
SP  - 9
VL  - 138
DO  - 10.1016/j.phytochem.2017.01.001
ER  - 

@article{
author = "Maksimović, Svetolik and Tadić, Vanja and Skala, Dejan and Žižović, Irena",
year = "2017",
abstract = "Helichrysum italicum presents a valuable source of natural bioactive compounds. In this work, a literature review of terpenes, phenolic compounds, and other less common phytochemicals from H. italicum with regard to application of different separation methods is presented. Data including extraction/separation methods and experimental conditions applied, obtained yields, number of identified compounds, content of different compound groups, and analytical techniques applied are shown as corresponding tables. Numerous biological activities of both isolates and individual compounds are emphasized. In addition, the data reported are discussed, and the directions for further investigations are proposed.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Separation of phytochemicals from Helichrysum italicum: An analysis of different isolation techniques and biological activity of prepared extracts",
pages = "28-9",
volume = "138",
doi = "10.1016/j.phytochem.2017.01.001"
}

Maksimović, S., Tadić, V., Skala, D.,& Žižović, I.. (2017). Separation of phytochemicals from Helichrysum italicum: An analysis of different isolation techniques and biological activity of prepared extracts. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford., 138, 9-28.
https://doi.org/10.1016/j.phytochem.2017.01.001

Maksimović S, Tadić V, Skala D, Žižović I. Separation of phytochemicals from Helichrysum italicum: An analysis of different isolation techniques and biological activity of prepared extracts. in Phytochemistry. 2017;138:9-28.
doi:10.1016/j.phytochem.2017.01.001 .

Maksimović, Svetolik, Tadić, Vanja, Skala, Dejan, Žižović, Irena, "Separation of phytochemicals from Helichrysum italicum: An analysis of different isolation techniques and biological activity of prepared extracts" in Phytochemistry, 138 (2017):9-28,
https://doi.org/10.1016/j.phytochem.2017.01.001 . .

TY  - CHAP
AU  - Meyer, Florian
AU  - Stamenić, Marko
AU  - Žižović, Irena
AU  - Eggers, Rudolf
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3489
AB  - A new trend in mathematical modeling of supercritical extraction process from plant material is presented. The most of the previously published models considered properties of the fixed bed of plant material during the extraction to be constant. This assumption might be quite true in the case of plant materials with relatively low quantity of extractables. However, the fixed bed property change may occur in the case of extraction from material with high quantities of extractables. Recently, mathematical model which took into account particle density, bed porosity and particle diameter as variables was derived. In this chapter, the model is further improved by introducing variable solubility of the extract in supercritical fluid. On the basis of new experimental results on the binary equilibrium of the system supercritical fluid - extract present in solid, a relationship between solubility in supercritical fluid and oil content in solid was established. The new model was derived which took into account particle density, bed porosity, particle diameter and solubility in supercritical fluid as variables. The model was verified on results from experiments in which the kinetics of supercritical extraction from rapseed was analyzed. Parameters of the model showed expected behaviour with respect to the change of particle size. Further analysis, shown in this chapter, showed that, if the dependency of solubility from the concentration in the solid phase is not accounted for, the model tends to overestimate the yield of the extraction. The new model is so far, the most realistic model and one of the most demanding models regarding experimental work and mathematical tools for the description of mass transfer in fixed beds.
T2  - Mathematical Research Summaries
T1  - Advances in mathematical modeling of supercritical extraction processes
EP  - 102
SP  - 101
VL  - 2
UR  - https://hdl.handle.net/21.15107/rcub_technorep_3489
ER  - 

@inbook{
author = "Meyer, Florian and Stamenić, Marko and Žižović, Irena and Eggers, Rudolf",
year = "2017",
abstract = "A new trend in mathematical modeling of supercritical extraction process from plant material is presented. The most of the previously published models considered properties of the fixed bed of plant material during the extraction to be constant. This assumption might be quite true in the case of plant materials with relatively low quantity of extractables. However, the fixed bed property change may occur in the case of extraction from material with high quantities of extractables. Recently, mathematical model which took into account particle density, bed porosity and particle diameter as variables was derived. In this chapter, the model is further improved by introducing variable solubility of the extract in supercritical fluid. On the basis of new experimental results on the binary equilibrium of the system supercritical fluid - extract present in solid, a relationship between solubility in supercritical fluid and oil content in solid was established. The new model was derived which took into account particle density, bed porosity, particle diameter and solubility in supercritical fluid as variables. The model was verified on results from experiments in which the kinetics of supercritical extraction from rapseed was analyzed. Parameters of the model showed expected behaviour with respect to the change of particle size. Further analysis, shown in this chapter, showed that, if the dependency of solubility from the concentration in the solid phase is not accounted for, the model tends to overestimate the yield of the extraction. The new model is so far, the most realistic model and one of the most demanding models regarding experimental work and mathematical tools for the description of mass transfer in fixed beds.",
journal = "Mathematical Research Summaries",
booktitle = "Advances in mathematical modeling of supercritical extraction processes",
pages = "102-101",
volume = "2",
url = "https://hdl.handle.net/21.15107/rcub_technorep_3489"
}

Meyer, F., Stamenić, M., Žižović, I.,& Eggers, R.. (2017). Advances in mathematical modeling of supercritical extraction processes. in Mathematical Research Summaries, 2, 101-102.
https://hdl.handle.net/21.15107/rcub_technorep_3489

Meyer F, Stamenić M, Žižović I, Eggers R. Advances in mathematical modeling of supercritical extraction processes. in Mathematical Research Summaries. 2017;2:101-102.
https://hdl.handle.net/21.15107/rcub_technorep_3489 .

Meyer, Florian, Stamenić, Marko, Žižović, Irena, Eggers, Rudolf, "Advances in mathematical modeling of supercritical extraction processes" in Mathematical Research Summaries, 2 (2017):101-102,
https://hdl.handle.net/21.15107/rcub_technorep_3489 .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Kuska, Robert
AU  - Lučić-Škorić, Marija
AU  - Kalagasidis Krušić, Melina
AU  - Frerich, Sulamith
AU  - Žižović, Irena
AU  - Ivanović, Jasna
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3219
AB  - The present work was aimed to study swelling kinetics of polylactic acid (PLA) and its impregnation with thymol in supercritical carbon dioxide (scCO2) medium. The influences of temperature and soaking time on the swelling kinetics and impregnation yield of PLA cylindrical disc and film were investigated. Swelling experiments were performed in a high pressure view cell at 10 MPa and temperatures of 40°C, 60°C and 75°C for 2 to 24 h. On the basis of swelling kinetics, pressure of 10 MPa and temperature of 40°C were chosen for supercritical solvent impregnation (SSI) of the PLA samples during 2 to24 h. The highest swelling extent was observed for the PLA monolith after 24 h treatment with pure scCO2 (7.5%) and scCO2 with thymol (118.3%). It was shown that sufficiently high amount of thymol can be loaded into both PLA monolith and film using SSI after only 2 h (10.0% and 6.6%, respectively). Monolith and film of PLA impregnated with thymol could be suitable for active food packaging and sterile medical disposables.
AB  - Prikazana studija je namenjena ispitivanju kinetike bubrenja polilaktida (PLA) i njegovoj impregnaciji timolom u natkritičnom ugljenik(IV)-oksidu (nkCO2). Praćen je uticaj temperature i operativnog vremena na kinetiku bubrenja i prinos impregnacije PLA cilindričnog diska i filma. Eksperimenti bubrenja su izvedeni u ćeliji za rad pod visokim pritiscima na 10 MPa and 40°C, 60°C i 75°C od 2 h do 24 h. Na osnovu kinetike bubrenja, natkritična impregnacija uzoraka PLA timolom je izvedena na pritisku od 10 MPa i temperaturi od 40°C tokom 2 do 24 h. Najveći stepen bubrenja je imao PLA disk na 10 MPa i 40°C nakon 24 h (7,5%) u sistemu sa čistim nkCO2 i u sistemu sa timolom (118,3%). Pokazano je da se dovoljno visok prinos impregnacije timola može postići nakon 2 h (10,0% za disk i 6,6% za film). PLA u formi diska i filma impregnirani timolom su pogodni materijali za aktivno pakovanje hrane i za sterilni medicinski pribor.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions
T1  - Kinetika bubrenja PLA i njegova impregnacija timolom upotrebom natkritičnog uglenik(IV)-oksida
EP  - 20
IS  - 1
SP  - 16
VL  - 71
DO  - 10.5937/tehnika1601016M
ER  - 

@article{
author = "Milovanović, Stoja and Kuska, Robert and Lučić-Škorić, Marija and Kalagasidis Krušić, Melina and Frerich, Sulamith and Žižović, Irena and Ivanović, Jasna",
year = "2016",
abstract = "The present work was aimed to study swelling kinetics of polylactic acid (PLA) and its impregnation with thymol in supercritical carbon dioxide (scCO2) medium. The influences of temperature and soaking time on the swelling kinetics and impregnation yield of PLA cylindrical disc and film were investigated. Swelling experiments were performed in a high pressure view cell at 10 MPa and temperatures of 40°C, 60°C and 75°C for 2 to 24 h. On the basis of swelling kinetics, pressure of 10 MPa and temperature of 40°C were chosen for supercritical solvent impregnation (SSI) of the PLA samples during 2 to24 h. The highest swelling extent was observed for the PLA monolith after 24 h treatment with pure scCO2 (7.5%) and scCO2 with thymol (118.3%). It was shown that sufficiently high amount of thymol can be loaded into both PLA monolith and film using SSI after only 2 h (10.0% and 6.6%, respectively). Monolith and film of PLA impregnated with thymol could be suitable for active food packaging and sterile medical disposables., Prikazana studija je namenjena ispitivanju kinetike bubrenja polilaktida (PLA) i njegovoj impregnaciji timolom u natkritičnom ugljenik(IV)-oksidu (nkCO2). Praćen je uticaj temperature i operativnog vremena na kinetiku bubrenja i prinos impregnacije PLA cilindričnog diska i filma. Eksperimenti bubrenja su izvedeni u ćeliji za rad pod visokim pritiscima na 10 MPa and 40°C, 60°C i 75°C od 2 h do 24 h. Na osnovu kinetike bubrenja, natkritična impregnacija uzoraka PLA timolom je izvedena na pritisku od 10 MPa i temperaturi od 40°C tokom 2 do 24 h. Najveći stepen bubrenja je imao PLA disk na 10 MPa i 40°C nakon 24 h (7,5%) u sistemu sa čistim nkCO2 i u sistemu sa timolom (118,3%). Pokazano je da se dovoljno visok prinos impregnacije timola može postići nakon 2 h (10,0% za disk i 6,6% za film). PLA u formi diska i filma impregnirani timolom su pogodni materijali za aktivno pakovanje hrane i za sterilni medicinski pribor.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions, Kinetika bubrenja PLA i njegova impregnacija timolom upotrebom natkritičnog uglenik(IV)-oksida",
pages = "20-16",
number = "1",
volume = "71",
doi = "10.5937/tehnika1601016M"
}

Milovanović, S., Kuska, R., Lučić-Škorić, M., Kalagasidis Krušić, M., Frerich, S., Žižović, I.,& Ivanović, J.. (2016). Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 71(1), 16-20.
https://doi.org/10.5937/tehnika1601016M

Milovanović S, Kuska R, Lučić-Škorić M, Kalagasidis Krušić M, Frerich S, Žižović I, Ivanović J. Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions. in Tehnika. 2016;71(1):16-20.
doi:10.5937/tehnika1601016M .

Milovanović, Stoja, Kuska, Robert, Lučić-Škorić, Marija, Kalagasidis Krušić, Melina, Frerich, Sulamith, Žižović, Irena, Ivanović, Jasna, "Swelling kinetics and impregnation of PLA with thymol under supercritical CO2 conditions" in Tehnika, 71, no. 1 (2016):16-20,
https://doi.org/10.5937/tehnika1601016M . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Aksentijević, Ksenija
AU  - Stojanović, Dušica
AU  - Ivanović, Jasna
AU  - Žižović, Irena
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3248
AB  - Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure techniques. Effect of thymol content on CA was confirmed by SEM, FTIR and DSC methods. Kinetic of thymol release from CA was tested using simulated gastric and intestinal fluids (hydrochloric acid and phosphate buffer saline). Results were correlated with Korsmeyer-Peppas and Weibull model. Depending on the thymol content and chemical nature of the release medium, the time of thymol release varied from one to three days indicating CA as a promising carrier of thymol with potential uses from medicine to agriculture. The impregnated CA showed antibacterial activity against 23 tested bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) which is particularly important bearing in mind that this strain causes fatal infections in humans and animals.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Application of cellulose acetate for controlled release of thymol
EP  - 353
SP  - 344
VL  - 147
DO  - 10.1016/j.carbpol.2016.03.093
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Aksentijević, Ksenija and Stojanović, Dušica and Ivanović, Jasna and Žižović, Irena",
year = "2016",
abstract = "Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure techniques. Effect of thymol content on CA was confirmed by SEM, FTIR and DSC methods. Kinetic of thymol release from CA was tested using simulated gastric and intestinal fluids (hydrochloric acid and phosphate buffer saline). Results were correlated with Korsmeyer-Peppas and Weibull model. Depending on the thymol content and chemical nature of the release medium, the time of thymol release varied from one to three days indicating CA as a promising carrier of thymol with potential uses from medicine to agriculture. The impregnated CA showed antibacterial activity against 23 tested bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) which is particularly important bearing in mind that this strain causes fatal infections in humans and animals.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Application of cellulose acetate for controlled release of thymol",
pages = "353-344",
volume = "147",
doi = "10.1016/j.carbpol.2016.03.093"
}

Milovanović, S., Marković, D., Aksentijević, K., Stojanović, D., Ivanović, J.,& Žižović, I.. (2016). Application of cellulose acetate for controlled release of thymol. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 147, 344-353.
https://doi.org/10.1016/j.carbpol.2016.03.093

Milovanović S, Marković D, Aksentijević K, Stojanović D, Ivanović J, Žižović I. Application of cellulose acetate for controlled release of thymol. in Carbohydrate Polymers. 2016;147:344-353.
doi:10.1016/j.carbpol.2016.03.093 .

Milovanović, Stoja, Marković, Darka, Aksentijević, Ksenija, Stojanović, Dušica, Ivanović, Jasna, Žižović, Irena, "Application of cellulose acetate for controlled release of thymol" in Carbohydrate Polymers, 147 (2016):344-353,
https://doi.org/10.1016/j.carbpol.2016.03.093 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Milovanović, Stoja
AU  - Žižović, Irena
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3336
AB  - Modification of native starch enables fabrication of a broad spectrum of technologically valuable products for food and non-food applications. Given the increased public concern about food safety and rigorous environmental regulations, a special attention is paid to non-thermal and organic solvent-free treatments of the starch-based materials. Supercritical carbon dioxide (scCO(2)) is considered to be an attractive processing aid for starch modification due to its unique physicochemical properties such as low viscosity, absence of surface tension, high diffusivity, tuneable density and controllable solvent strength, low critical parameters (7.38MPa, 31.1 degrees C), availability, and environmental acceptability. This is the first review on different use of scCO(2) as a processing aid in setting functionality of starch-based materials including scCO(2)-assisted gelatinization, fabrication of porous materials, impregnation, and chemical modification. In these processes, scCO(2) is used as a plasticizer, blowing agent, solvent, medium or anti-solvent to alter structural, and/or physicochemical properties of starch. The advantages of the scCO(2)-assisted processes for starch modification over the corresponding conventional techniques were discussed in detail.
PB  - Wiley-VCH Verlag Gmbh, Weinheim
T2  - Starch-Starke
T1  - Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials
EP  - 833
IS  - 9-10
SP  - 821
VL  - 68
DO  - 10.1002/star.201500194
ER  - 

@article{
author = "Ivanović, Jasna and Milovanović, Stoja and Žižović, Irena",
year = "2016",
abstract = "Modification of native starch enables fabrication of a broad spectrum of technologically valuable products for food and non-food applications. Given the increased public concern about food safety and rigorous environmental regulations, a special attention is paid to non-thermal and organic solvent-free treatments of the starch-based materials. Supercritical carbon dioxide (scCO(2)) is considered to be an attractive processing aid for starch modification due to its unique physicochemical properties such as low viscosity, absence of surface tension, high diffusivity, tuneable density and controllable solvent strength, low critical parameters (7.38MPa, 31.1 degrees C), availability, and environmental acceptability. This is the first review on different use of scCO(2) as a processing aid in setting functionality of starch-based materials including scCO(2)-assisted gelatinization, fabrication of porous materials, impregnation, and chemical modification. In these processes, scCO(2) is used as a plasticizer, blowing agent, solvent, medium or anti-solvent to alter structural, and/or physicochemical properties of starch. The advantages of the scCO(2)-assisted processes for starch modification over the corresponding conventional techniques were discussed in detail.",
publisher = "Wiley-VCH Verlag Gmbh, Weinheim",
journal = "Starch-Starke",
title = "Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials",
pages = "833-821",
number = "9-10",
volume = "68",
doi = "10.1002/star.201500194"
}

Ivanović, J., Milovanović, S.,& Žižović, I.. (2016). Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials. in Starch-Starke
Wiley-VCH Verlag Gmbh, Weinheim., 68(9-10), 821-833.
https://doi.org/10.1002/star.201500194

Ivanović J, Milovanović S, Žižović I. Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials. in Starch-Starke. 2016;68(9-10):821-833.
doi:10.1002/star.201500194 .

Ivanović, Jasna, Milovanović, Stoja, Žižović, Irena, "Utilization of supercritical CO2 as a processing aid in setting functionality of starch-based materials" in Starch-Starke, 68, no. 9-10 (2016):821-833,
https://doi.org/10.1002/star.201500194 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Knauer, Sandra
AU  - Fanovich, Alejandra
AU  - Milovanović, Stoja
AU  - Stamenić, Marko
AU  - Jaeger, Philip
AU  - Žižović, Irena
AU  - Eggers, Rudolf
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3407
AB  - The potential of supercritical carbon dioxide (scCO(2)) processing of polycaprolactone (Pa) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 degrees C) was analyzed and quantified. The effect of scCO(2) sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 degrees C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size similar to 200-300 mu m), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO(2) solubility (0.25-0.30 g/g) and mass transfer rate (similar to 10(-10) m(2)/s) in the polymer phase as well as its great plasticizing effect (-Delta T-m = 26.4-27.4 degrees C). Higher saturation of the polymer phase with scCO(2) (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO(2) ( gt 5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
EP  - 498
SP  - 486
VL  - 107
DO  - 10.1016/j.supflu.2015.07.001
ER  - 

@article{
author = "Ivanović, Jasna and Knauer, Sandra and Fanovich, Alejandra and Milovanović, Stoja and Stamenić, Marko and Jaeger, Philip and Žižović, Irena and Eggers, Rudolf",
year = "2016",
abstract = "The potential of supercritical carbon dioxide (scCO(2)) processing of polycaprolactone (Pa) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 degrees C) was analyzed and quantified. The effect of scCO(2) sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 degrees C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size similar to 200-300 mu m), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO(2) solubility (0.25-0.30 g/g) and mass transfer rate (similar to 10(-10) m(2)/s) in the polymer phase as well as its great plasticizing effect (-Delta T-m = 26.4-27.4 degrees C). Higher saturation of the polymer phase with scCO(2) (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO(2) ( gt 5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA",
pages = "498-486",
volume = "107",
doi = "10.1016/j.supflu.2015.07.001"
}

Ivanović, J., Knauer, S., Fanovich, A., Milovanović, S., Stamenić, M., Jaeger, P., Žižović, I.,& Eggers, R.. (2016). Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 107, 486-498.
https://doi.org/10.1016/j.supflu.2015.07.001

Ivanović J, Knauer S, Fanovich A, Milovanović S, Stamenić M, Jaeger P, Žižović I, Eggers R. Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA. in Journal of Supercritical Fluids. 2016;107:486-498.
doi:10.1016/j.supflu.2015.07.001 .

Ivanović, Jasna, Knauer, Sandra, Fanovich, Alejandra, Milovanović, Stoja, Stamenić, Marko, Jaeger, Philip, Žižović, Irena, Eggers, Rudolf, "Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA" in Journal of Supercritical Fluids, 107 (2016):486-498,
https://doi.org/10.1016/j.supflu.2015.07.001 . .