TY  - CONF
AU  - Zvicer, Jovana
AU  - Samardžić, M.
AU  - Mišković-Stanković, Vesna
AU  - Obradović, Bojana
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2880
AB  - Alginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression.
PB  - 15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015
C3  - 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
T1  - Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures
DO  - 10.1109/BIBE.2015.7367664
ER  - 

@conference{
author = "Zvicer, Jovana and Samardžić, M. and Mišković-Stanković, Vesna and Obradović, Bojana",
year = "2015",
abstract = "Alginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression.",
publisher = "15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015",
journal = "2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015",
title = "Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures",
doi = "10.1109/BIBE.2015.7367664"
}

Zvicer, J., Samardžić, M., Mišković-Stanković, V.,& Obradović, B.. (2015). Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures. in 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015..
https://doi.org/10.1109/BIBE.2015.7367664

Zvicer J, Samardžić M, Mišković-Stanković V, Obradović B. Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures. in 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015. 2015;.
doi:10.1109/BIBE.2015.7367664 .

Zvicer, Jovana, Samardžić, M., Mišković-Stanković, Vesna, Obradović, Bojana, "Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures" in 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015 (2015),
https://doi.org/10.1109/BIBE.2015.7367664 . .