TY  - JOUR
AU  - Vukomanović, Marija
AU  - Škapin, Srečo Davor
AU  - Jančar, Boštjan
AU  - Maksin, Tatjana
AU  - Ignjatović, Nenad
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5650
AB  - Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces B: Biointerfaces
T1  - Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery
EP  - 413
IS  - 2
SP  - 404
VL  - 82
DO  - 10.1016/j.colsurfb.2010.09.011
UR  - https://hdl.handle.net/21.15107/rcub_dais_2749
ER  - 

@article{
author = "Vukomanović, Marija and Škapin, Srečo Davor and Jančar, Boštjan and Maksin, Tatjana and Ignjatović, Nenad and Uskoković, Vuk and Uskoković, Dragan",
year = "2011",
abstract = "Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces B: Biointerfaces",
title = "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery",
pages = "413-404",
number = "2",
volume = "82",
doi = "10.1016/j.colsurfb.2010.09.011",
url = "https://hdl.handle.net/21.15107/rcub_dais_2749"
}

Vukomanović, M., Škapin, S. D., Jančar, B., Maksin, T., Ignjatović, N., Uskoković, V.,& Uskoković, D.. (2011). Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces B: Biointerfaces, 82(2), 404-413.
https://doi.org/10.1016/j.colsurfb.2010.09.011
https://hdl.handle.net/21.15107/rcub_dais_2749

Vukomanović M, Škapin SD, Jančar B, Maksin T, Ignjatović N, Uskoković V, Uskoković D. Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces B: Biointerfaces. 2011;82(2):404-413.
doi:10.1016/j.colsurfb.2010.09.011
https://hdl.handle.net/21.15107/rcub_dais_2749 .

Vukomanović, Marija, Škapin, Srečo Davor, Jančar, Boštjan, Maksin, Tatjana, Ignjatović, Nenad, Uskoković, Vuk, Uskoković, Dragan, "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery" in Colloids and Surfaces B: Biointerfaces, 82, no. 2 (2011):404-413,
https://doi.org/10.1016/j.colsurfb.2010.09.011 .,
https://hdl.handle.net/21.15107/rcub_dais_2749 .

TY  - JOUR
AU  - Vuković, Goran D.
AU  - Marinković, Aleksandar
AU  - Čolić, Miodrag
AU  - Ristić, Mirjana
AU  - Aleksić, Radoslav
AU  - Perić-Grujić, Aleksandra
AU  - Uskoković, Petar
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1714
AB  - Surface functionalization of multi-walled carbon nanotubes (MWCNTs) by ethylenediamine, via chemical modification of carboxyl groups, using O-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, was performed. The resulting materials were characterized by different techniques, such as FTIR, TGA and elemental analysis. Biocompatibility studies showed that the functionalized MWCNTs, at concentrations between 1 and 50 mu g mL(-1), were not cytotoxic for the fibroblast L929 cell line. In batch tests, the influences of solution pH, contact time, initial metal ion concentration and temperature on the sorption of Cd2+ ions onto raw-MWCNTs (raw-MWCNT), oxidized MWCNTs (o-MWCNT) and ethylenediamine-functionalized MWCNTs (e-MWCNT) were studied. The adsorption of Cd2+ ions by o-MWCNT and e-MWCNT was strongly pH dependent. The time dependent Cd2+ sorption onto raw-MWCNT, o-MWCNT and e-MWCNT can be described by a pseudo-second-order kinetic model. The Langmuir isotherm model agrees well with the equilibrium experimental data. The maximum capacity was obtained for e-MWCNT, 25.7 mgg(-1), at 45 degrees C. The thermodynamic parameters were also deduced for the adsorption of Cd2+ ions on raw-MWCNT, o-MWCNT and e-MWCNT and the results showed that the adsorption was spontaneous and endothermic.
PB  - Elsevier Science Sa, Lausanne
T2  - Chemical Engineering Journal
T1  - Removal of cadmium from aqueous solutions by oxidized and ethylenediamine-functionalized multi-walled carbon nanotubes
EP  - 248
IS  - 1
SP  - 238
VL  - 157
DO  - 10.1016/j.cej.2009.11.026
ER  - 

@article{
author = "Vuković, Goran D. and Marinković, Aleksandar and Čolić, Miodrag and Ristić, Mirjana and Aleksić, Radoslav and Perić-Grujić, Aleksandra and Uskoković, Petar",
year = "2010",
abstract = "Surface functionalization of multi-walled carbon nanotubes (MWCNTs) by ethylenediamine, via chemical modification of carboxyl groups, using O-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, was performed. The resulting materials were characterized by different techniques, such as FTIR, TGA and elemental analysis. Biocompatibility studies showed that the functionalized MWCNTs, at concentrations between 1 and 50 mu g mL(-1), were not cytotoxic for the fibroblast L929 cell line. In batch tests, the influences of solution pH, contact time, initial metal ion concentration and temperature on the sorption of Cd2+ ions onto raw-MWCNTs (raw-MWCNT), oxidized MWCNTs (o-MWCNT) and ethylenediamine-functionalized MWCNTs (e-MWCNT) were studied. The adsorption of Cd2+ ions by o-MWCNT and e-MWCNT was strongly pH dependent. The time dependent Cd2+ sorption onto raw-MWCNT, o-MWCNT and e-MWCNT can be described by a pseudo-second-order kinetic model. The Langmuir isotherm model agrees well with the equilibrium experimental data. The maximum capacity was obtained for e-MWCNT, 25.7 mgg(-1), at 45 degrees C. The thermodynamic parameters were also deduced for the adsorption of Cd2+ ions on raw-MWCNT, o-MWCNT and e-MWCNT and the results showed that the adsorption was spontaneous and endothermic.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Chemical Engineering Journal",
title = "Removal of cadmium from aqueous solutions by oxidized and ethylenediamine-functionalized multi-walled carbon nanotubes",
pages = "248-238",
number = "1",
volume = "157",
doi = "10.1016/j.cej.2009.11.026"
}

Vuković, G. D., Marinković, A., Čolić, M., Ristić, M., Aleksić, R., Perić-Grujić, A.,& Uskoković, P.. (2010). Removal of cadmium from aqueous solutions by oxidized and ethylenediamine-functionalized multi-walled carbon nanotubes. in Chemical Engineering Journal
Elsevier Science Sa, Lausanne., 157(1), 238-248.
https://doi.org/10.1016/j.cej.2009.11.026

Vuković GD, Marinković A, Čolić M, Ristić M, Aleksić R, Perić-Grujić A, Uskoković P. Removal of cadmium from aqueous solutions by oxidized and ethylenediamine-functionalized multi-walled carbon nanotubes. in Chemical Engineering Journal. 2010;157(1):238-248.
doi:10.1016/j.cej.2009.11.026 .

Vuković, Goran D., Marinković, Aleksandar, Čolić, Miodrag, Ristić, Mirjana, Aleksić, Radoslav, Perić-Grujić, Aleksandra, Uskoković, Petar, "Removal of cadmium from aqueous solutions by oxidized and ethylenediamine-functionalized multi-walled carbon nanotubes" in Chemical Engineering Journal, 157, no. 1 (2010):238-248,
https://doi.org/10.1016/j.cej.2009.11.026 . .

TY  - JOUR
AU  - Vuković, Goran D.
AU  - Tomić, Sergej
AU  - Marinković, Aleksandar
AU  - Radmilović, Velimir R.
AU  - Uskoković, Petar
AU  - Čolić, Miodrag
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1648
AB  - Dapsone is an anti-microbial and anti-inflammatory drug. Water-dispersible dapsone-modified multi-wall carbon nanotubes (dap-MWCNTs) were prepared by chemical modification of the carboxyl groups introduced on the surface of the nanotubes using O-(7-aza-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA). The modification was confirmed by Fourier-transform infrared spectroscopy, transmission election microscopy and thermogravimetric analysis. The biological effect of dap-MWCNTs was tested using rat peritoneal macrophages (PMempty set). By confocal laser microscopy and flow cytometry, it was shown that the dap-MWCNTs were rapidly ingested by PMempty set as were the control, oxidized o-MWCNTs. Neither dap-MWCNTs at lower concentrations (up to 50 mu g/ml), nor o-MWCNTs, at equivalent concentrations, respectively affected the viability of PMempty set, while higher concentrations triggered apoptosis. Apoptosis of PMempty set induced by the control, o-MWCNTs, was higher than that induced by dap-MWCNTs and it correlated with the induction of oxidative stress. In contrast, dap-MWCNTs did not trigger oxidative stress but caused apoptosis of PMempty set predominantly after prolonged cultivation (3 days). Although equivalent concentrations of soluble dapsone induced oxidative stress, they were anti-apoptotic. Cumulatively, the obtained results show the complexity of dap-MWCNT/PMempty set interactions and suggest that this complex could be investigated for the treatment of dapsone-sensitive intracellular microorganisms or inflammatory diseases responding to dapsone therapy.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Carbon
T1  - The response of peritoneal macrophages to dapsone covalently attached on the surface of carbon nanotubes
EP  - 3078
IS  - 11
SP  - 3066
VL  - 48
DO  - 10.1016/j.carbon.2010.04.043
ER  - 

@article{
author = "Vuković, Goran D. and Tomić, Sergej and Marinković, Aleksandar and Radmilović, Velimir R. and Uskoković, Petar and Čolić, Miodrag",
year = "2010",
abstract = "Dapsone is an anti-microbial and anti-inflammatory drug. Water-dispersible dapsone-modified multi-wall carbon nanotubes (dap-MWCNTs) were prepared by chemical modification of the carboxyl groups introduced on the surface of the nanotubes using O-(7-aza-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA). The modification was confirmed by Fourier-transform infrared spectroscopy, transmission election microscopy and thermogravimetric analysis. The biological effect of dap-MWCNTs was tested using rat peritoneal macrophages (PMempty set). By confocal laser microscopy and flow cytometry, it was shown that the dap-MWCNTs were rapidly ingested by PMempty set as were the control, oxidized o-MWCNTs. Neither dap-MWCNTs at lower concentrations (up to 50 mu g/ml), nor o-MWCNTs, at equivalent concentrations, respectively affected the viability of PMempty set, while higher concentrations triggered apoptosis. Apoptosis of PMempty set induced by the control, o-MWCNTs, was higher than that induced by dap-MWCNTs and it correlated with the induction of oxidative stress. In contrast, dap-MWCNTs did not trigger oxidative stress but caused apoptosis of PMempty set predominantly after prolonged cultivation (3 days). Although equivalent concentrations of soluble dapsone induced oxidative stress, they were anti-apoptotic. Cumulatively, the obtained results show the complexity of dap-MWCNT/PMempty set interactions and suggest that this complex could be investigated for the treatment of dapsone-sensitive intracellular microorganisms or inflammatory diseases responding to dapsone therapy.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Carbon",
title = "The response of peritoneal macrophages to dapsone covalently attached on the surface of carbon nanotubes",
pages = "3078-3066",
number = "11",
volume = "48",
doi = "10.1016/j.carbon.2010.04.043"
}

Vuković, G. D., Tomić, S., Marinković, A., Radmilović, V. R., Uskoković, P.,& Čolić, M.. (2010). The response of peritoneal macrophages to dapsone covalently attached on the surface of carbon nanotubes. in Carbon
Pergamon-Elsevier Science Ltd, Oxford., 48(11), 3066-3078.
https://doi.org/10.1016/j.carbon.2010.04.043

Vuković GD, Tomić S, Marinković A, Radmilović VR, Uskoković P, Čolić M. The response of peritoneal macrophages to dapsone covalently attached on the surface of carbon nanotubes. in Carbon. 2010;48(11):3066-3078.
doi:10.1016/j.carbon.2010.04.043 .

Vuković, Goran D., Tomić, Sergej, Marinković, Aleksandar, Radmilović, Velimir R., Uskoković, Petar, Čolić, Miodrag, "The response of peritoneal macrophages to dapsone covalently attached on the surface of carbon nanotubes" in Carbon, 48, no. 11 (2010):3066-3078,
https://doi.org/10.1016/j.carbon.2010.04.043 . .

TY  - JOUR
AU  - Torki, A. M.
AU  - Živković, Irena
AU  - Radmilović, Velimir R.
AU  - Stojanović, Dušica
AU  - Radojević, Vesna
AU  - Uskoković, Petar
AU  - Aleksić, Radoslav
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1710
AB  - This work reports the preparation of SiO(2) and TiO(2)/poly (vinyl butyral) nanocomposites with enhanced dynamic mechanical properties. Silica and titania nanoparticles were introduced in the matrix as the neat powder and as colloidal sol using the melt mixing process. Composites reinforced with colloidal sol silica and titania showed higher mechanical properties than the ones reinforced with as-received particles. When sol TiO(2) particles are used, the highest increase of storage modulus of about 54% is obtained for 5 wt% loading, while for sol SiO(2), the storage modulus increases with the addition of nanosilica with the largest increase of about 99% for 7 wt% loading. In addition, nanocomposites were introduced within Kevlar/PVB composites. The addition of 5 wt% silica and titania colloidal sol lead to the remarkable increase of the storage modulus for about 98 and 65%, respectively. Largest contribution of nanoreinforcements in lowering the glass transition temperature is observed for 7 wt% loading of TiO(2) and SiO(2) colloidal sol.
PB  - World Scientific Publ Co Pte Ltd, Singapore
T2  - International Journal of Modern Physics B
T1  - Dynamic mechanical properties of nanocomposites with poly (vinyl butyral) matrix
EP  - 812
IS  - 6-7
SP  - 805
VL  - 24
DO  - 10.1142/S0217979210064447
ER  - 

@article{
author = "Torki, A. M. and Živković, Irena and Radmilović, Velimir R. and Stojanović, Dušica and Radojević, Vesna and Uskoković, Petar and Aleksić, Radoslav",
year = "2010",
abstract = "This work reports the preparation of SiO(2) and TiO(2)/poly (vinyl butyral) nanocomposites with enhanced dynamic mechanical properties. Silica and titania nanoparticles were introduced in the matrix as the neat powder and as colloidal sol using the melt mixing process. Composites reinforced with colloidal sol silica and titania showed higher mechanical properties than the ones reinforced with as-received particles. When sol TiO(2) particles are used, the highest increase of storage modulus of about 54% is obtained for 5 wt% loading, while for sol SiO(2), the storage modulus increases with the addition of nanosilica with the largest increase of about 99% for 7 wt% loading. In addition, nanocomposites were introduced within Kevlar/PVB composites. The addition of 5 wt% silica and titania colloidal sol lead to the remarkable increase of the storage modulus for about 98 and 65%, respectively. Largest contribution of nanoreinforcements in lowering the glass transition temperature is observed for 7 wt% loading of TiO(2) and SiO(2) colloidal sol.",
publisher = "World Scientific Publ Co Pte Ltd, Singapore",
journal = "International Journal of Modern Physics B",
title = "Dynamic mechanical properties of nanocomposites with poly (vinyl butyral) matrix",
pages = "812-805",
number = "6-7",
volume = "24",
doi = "10.1142/S0217979210064447"
}

Torki, A. M., Živković, I., Radmilović, V. R., Stojanović, D., Radojević, V., Uskoković, P.,& Aleksić, R.. (2010). Dynamic mechanical properties of nanocomposites with poly (vinyl butyral) matrix. in International Journal of Modern Physics B
World Scientific Publ Co Pte Ltd, Singapore., 24(6-7), 805-812.
https://doi.org/10.1142/S0217979210064447

Torki AM, Živković I, Radmilović VR, Stojanović D, Radojević V, Uskoković P, Aleksić R. Dynamic mechanical properties of nanocomposites with poly (vinyl butyral) matrix. in International Journal of Modern Physics B. 2010;24(6-7):805-812.
doi:10.1142/S0217979210064447 .

Torki, A. M., Živković, Irena, Radmilović, Velimir R., Stojanović, Dušica, Radojević, Vesna, Uskoković, Petar, Aleksić, Radoslav, "Dynamic mechanical properties of nanocomposites with poly (vinyl butyral) matrix" in International Journal of Modern Physics B, 24, no. 6-7 (2010):805-812,
https://doi.org/10.1142/S0217979210064447 . .

TY  - JOUR
AU  - Stojanović, Dušica
AU  - Orlović, Aleksandar
AU  - Glišić, Sandra
AU  - Marković, Smilja
AU  - Radmilović, Velimir R.
AU  - Uskoković, Petar
AU  - Aleksić, Radoslav
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1701
AB  - The objective of this study is to investigate and compare methods of nanosilica coating with gamma-methacryloxypropyltrimethoxy (MEMO) silane using supercritical carbon dioxide and carbon dioxide-ethanol mixture. Characterization of grafted silane coupling agent on the nanosilica surface was performed by the infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The d(50) value and particle size distribution were determined by laser particle size analyzer (PSA). The operating parameters of silanization process at 40 degrees C, such as the silica/silane weight ratio, the presence of ethanol, and the pressure, were found to be important for the successful coating of silica particles with minimum agglomeration. The results indicate that presence of ethanol in high-pressure carbon dioxide plays an important role in achieving successful deagglomeration of coated nanoparticles. Dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) revealed that dispersion of the silica particles in the PMMA matrix and interfacial adhesion between silica particles and polymer matrix were enhanced, when silica nanoparticles treated with silane under high pressure of carbon dioxide and ethanol were used for the nanocomposite preparation.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol
EP  - 284
IS  - 3
SP  - 276
VL  - 52
DO  - 10.1016/j.supflu.2010.02.004
ER  - 

@article{
author = "Stojanović, Dušica and Orlović, Aleksandar and Glišić, Sandra and Marković, Smilja and Radmilović, Velimir R. and Uskoković, Petar and Aleksić, Radoslav",
year = "2010",
abstract = "The objective of this study is to investigate and compare methods of nanosilica coating with gamma-methacryloxypropyltrimethoxy (MEMO) silane using supercritical carbon dioxide and carbon dioxide-ethanol mixture. Characterization of grafted silane coupling agent on the nanosilica surface was performed by the infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The d(50) value and particle size distribution were determined by laser particle size analyzer (PSA). The operating parameters of silanization process at 40 degrees C, such as the silica/silane weight ratio, the presence of ethanol, and the pressure, were found to be important for the successful coating of silica particles with minimum agglomeration. The results indicate that presence of ethanol in high-pressure carbon dioxide plays an important role in achieving successful deagglomeration of coated nanoparticles. Dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) revealed that dispersion of the silica particles in the PMMA matrix and interfacial adhesion between silica particles and polymer matrix were enhanced, when silica nanoparticles treated with silane under high pressure of carbon dioxide and ethanol were used for the nanocomposite preparation.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol",
pages = "284-276",
number = "3",
volume = "52",
doi = "10.1016/j.supflu.2010.02.004"
}

Stojanović, D., Orlović, A., Glišić, S., Marković, S., Radmilović, V. R., Uskoković, P.,& Aleksić, R.. (2010). Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 52(3), 276-284.
https://doi.org/10.1016/j.supflu.2010.02.004

Stojanović D, Orlović A, Glišić S, Marković S, Radmilović VR, Uskoković P, Aleksić R. Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol. in Journal of Supercritical Fluids. 2010;52(3):276-284.
doi:10.1016/j.supflu.2010.02.004 .

Stojanović, Dušica, Orlović, Aleksandar, Glišić, Sandra, Marković, Smilja, Radmilović, Velimir R., Uskoković, Petar, Aleksić, Radoslav, "Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol" in Journal of Supercritical Fluids, 52, no. 3 (2010):276-284,
https://doi.org/10.1016/j.supflu.2010.02.004 . .

TY  - JOUR
AU  - Vuković, Goran D.
AU  - Marinković, Aleksandar
AU  - Obradović, Maja
AU  - Radmilović, V.
AU  - Čolić, Miodrag
AU  - Aleksić, Radoslav
AU  - Uskoković, Petar
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1512
AB  - Surface functionalization of multi-walled carbon nanotubes (MWCNTs), with amino groups via chemical modification of carboxyl groups introduced on the nanotube surface, using O-(7-azabenzotriazol-1-yl)-N, N,N',N'-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA) is reported. The N-HATU coupling agent provides faster reaction rate and the reaction occurs at lower temperature compared to amidation and acylation-amidation chemistry. The amines, 1,6-hexanediamine (HDA), diethylenetriamine (DETA), triethylenetetramine (TETA) and 1,4-phenylenediamine (PDA) were used. The resulting materials were characterized with different techniques such as FTIR, XRD, elemental analysis, TGA, TEM, UV-vis spectroscopy and cyclic voltammetry. MWCNTs functionalized with PDA posses the best dispersibility and electron transfer properties in comparison to the others amines. Functionalized MWCNTs, at the concentrations between 1 and 50 mu g ml(-1), were not cytotoxic for the fibroblast L929 cell line. However, the concentrations of MWCNTs higher of 10 mu g ml(-1) reduced cell growth and this effect correlated positively with the degree of their uptake by L929 cells.
PB  - Elsevier Science Bv, Amsterdam
T2  - Applied Surface Science
T1  - Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes
EP  - 8075
IS  - 18
SP  - 8067
VL  - 255
DO  - 10.1016/j.apsusc.2009.05.016
ER  - 

@article{
author = "Vuković, Goran D. and Marinković, Aleksandar and Obradović, Maja and Radmilović, V. and Čolić, Miodrag and Aleksić, Radoslav and Uskoković, Petar",
year = "2009",
abstract = "Surface functionalization of multi-walled carbon nanotubes (MWCNTs), with amino groups via chemical modification of carboxyl groups introduced on the nanotube surface, using O-(7-azabenzotriazol-1-yl)-N, N,N',N'-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA) is reported. The N-HATU coupling agent provides faster reaction rate and the reaction occurs at lower temperature compared to amidation and acylation-amidation chemistry. The amines, 1,6-hexanediamine (HDA), diethylenetriamine (DETA), triethylenetetramine (TETA) and 1,4-phenylenediamine (PDA) were used. The resulting materials were characterized with different techniques such as FTIR, XRD, elemental analysis, TGA, TEM, UV-vis spectroscopy and cyclic voltammetry. MWCNTs functionalized with PDA posses the best dispersibility and electron transfer properties in comparison to the others amines. Functionalized MWCNTs, at the concentrations between 1 and 50 mu g ml(-1), were not cytotoxic for the fibroblast L929 cell line. However, the concentrations of MWCNTs higher of 10 mu g ml(-1) reduced cell growth and this effect correlated positively with the degree of their uptake by L929 cells.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Applied Surface Science",
title = "Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes",
pages = "8075-8067",
number = "18",
volume = "255",
doi = "10.1016/j.apsusc.2009.05.016"
}

Vuković, G. D., Marinković, A., Obradović, M., Radmilović, V., Čolić, M., Aleksić, R.,& Uskoković, P.. (2009). Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes. in Applied Surface Science
Elsevier Science Bv, Amsterdam., 255(18), 8067-8075.
https://doi.org/10.1016/j.apsusc.2009.05.016

Vuković GD, Marinković A, Obradović M, Radmilović V, Čolić M, Aleksić R, Uskoković P. Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes. in Applied Surface Science. 2009;255(18):8067-8075.
doi:10.1016/j.apsusc.2009.05.016 .

Vuković, Goran D., Marinković, Aleksandar, Obradović, Maja, Radmilović, V., Čolić, Miodrag, Aleksić, Radoslav, Uskoković, Petar, "Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes" in Applied Surface Science, 255, no. 18 (2009):8067-8075,
https://doi.org/10.1016/j.apsusc.2009.05.016 . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Mitrić, Miodrag
AU  - Mitrovic, M.
AU  - Tomić, Simonida
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5495
AB  - The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable. (C) 2006 Elsevier Ltd. All rights reserved.
T2  - Radiation Physics and Chemistry
T1  - Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial
EP  - 728
IS  - 4
SP  - 722
VL  - 76
DO  - 10.1016/j.radphyschem.2006.02.013
UR  - https://hdl.handle.net/21.15107/rcub_dais_2752
ER  - 

@article{
author = "Suljovrujić, Edin H. and Ignjatović, Nenad and Uskoković, Dragan and Mitrić, Miodrag and Mitrovic, M. and Tomić, Simonida",
year = "2007",
abstract = "The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable. (C) 2006 Elsevier Ltd. All rights reserved.",
journal = "Radiation Physics and Chemistry",
title = "Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial",
pages = "728-722",
number = "4",
volume = "76",
doi = "10.1016/j.radphyschem.2006.02.013",
url = "https://hdl.handle.net/21.15107/rcub_dais_2752"
}

Suljovrujić, E. H., Ignjatović, N., Uskoković, D., Mitrić, M., Mitrovic, M.,& Tomić, S.. (2007). Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial. in Radiation Physics and Chemistry, 76(4), 722-728.
https://doi.org/10.1016/j.radphyschem.2006.02.013
https://hdl.handle.net/21.15107/rcub_dais_2752

Suljovrujić EH, Ignjatović N, Uskoković D, Mitrić M, Mitrovic M, Tomić S. Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial. in Radiation Physics and Chemistry. 2007;76(4):722-728.
doi:10.1016/j.radphyschem.2006.02.013
https://hdl.handle.net/21.15107/rcub_dais_2752 .

Suljovrujić, Edin H., Ignjatović, Nenad, Uskoković, Dragan, Mitrić, Miodrag, Mitrovic, M., Tomić, Simonida, "Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial" in Radiation Physics and Chemistry, 76, no. 4 (2007):722-728,
https://doi.org/10.1016/j.radphyschem.2006.02.013 .,
https://hdl.handle.net/21.15107/rcub_dais_2752 .

TY  - JOUR
AU  - Balać, Igor
AU  - Aleksendrić, D.
AU  - Tang, C. Y.
AU  - Tsui, C. P.
AU  - Uskoković, Petar
AU  - Uskoković, Dragan
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1044
AB  - In this work, a combination of nanoindentation experiment and finite element modeling is proposed in order to obtain approximate material behavior of PLLA polymer in hydroxyapatite (HAp)/poly-L-lactide (PLLA) composite. Knowing these properties is important since the processing conditions used in hot pressing of composites with thermoplastic matrix strongly influence final mechanical properties of material in the solid state. A bi-linear material behavior is adopted for the polymer phase of the HAp/PLLA composite. Material behavior model, stress-strain curve, is determined by modulus of elasticity, yield stress and work-hardening rate. This combined method is proposed to determine material behavior before (modulus of elasticity) and after yield point (work hardening rate) of polymer phase after the hot-pressing of the composite. .
PB  - Savez inženjera metalurgije Srbije, Beograd
T2  - Metalurgija
T1  - Approximation of material behaviour of PLLA polymer in HAp/PLLA biocomposite material using nanoindentation and finite element method
EP  - 286
IS  - 4
SP  - 277
VL  - 13
UR  - https://hdl.handle.net/21.15107/rcub_technorep_1044
ER  - 

@article{
author = "Balać, Igor and Aleksendrić, D. and Tang, C. Y. and Tsui, C. P. and Uskoković, Petar and Uskoković, Dragan",
year = "2007",
abstract = "In this work, a combination of nanoindentation experiment and finite element modeling is proposed in order to obtain approximate material behavior of PLLA polymer in hydroxyapatite (HAp)/poly-L-lactide (PLLA) composite. Knowing these properties is important since the processing conditions used in hot pressing of composites with thermoplastic matrix strongly influence final mechanical properties of material in the solid state. A bi-linear material behavior is adopted for the polymer phase of the HAp/PLLA composite. Material behavior model, stress-strain curve, is determined by modulus of elasticity, yield stress and work-hardening rate. This combined method is proposed to determine material behavior before (modulus of elasticity) and after yield point (work hardening rate) of polymer phase after the hot-pressing of the composite. .",
publisher = "Savez inženjera metalurgije Srbije, Beograd",
journal = "Metalurgija",
title = "Approximation of material behaviour of PLLA polymer in HAp/PLLA biocomposite material using nanoindentation and finite element method",
pages = "286-277",
number = "4",
volume = "13",
url = "https://hdl.handle.net/21.15107/rcub_technorep_1044"
}

Balać, I., Aleksendrić, D., Tang, C. Y., Tsui, C. P., Uskoković, P.,& Uskoković, D.. (2007). Approximation of material behaviour of PLLA polymer in HAp/PLLA biocomposite material using nanoindentation and finite element method. in Metalurgija
Savez inženjera metalurgije Srbije, Beograd., 13(4), 277-286.
https://hdl.handle.net/21.15107/rcub_technorep_1044

Balać I, Aleksendrić D, Tang CY, Tsui CP, Uskoković P, Uskoković D. Approximation of material behaviour of PLLA polymer in HAp/PLLA biocomposite material using nanoindentation and finite element method. in Metalurgija. 2007;13(4):277-286.
https://hdl.handle.net/21.15107/rcub_technorep_1044 .

Balać, Igor, Aleksendrić, D., Tang, C. Y., Tsui, C. P., Uskoković, Petar, Uskoković, Dragan, "Approximation of material behaviour of PLLA polymer in HAp/PLLA biocomposite material using nanoindentation and finite element method" in Metalurgija, 13, no. 4 (2007):277-286,
https://hdl.handle.net/21.15107/rcub_technorep_1044 .