TY  - JOUR
AU  - Porobić, Slavica
AU  - Božić, Bojan
AU  - Dramićanin, Miroslav
AU  - Vitnik, Vesna
AU  - Vitnik, Željko
AU  - Marinović-Cincović, Milena
AU  - Mijin, Dušan
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4482
AB  - A series of nine 5-(4-substituted phenylazo)-3-amido-6-hydroxy-4-methyl-2-pyridones were synthesized and characterized by FT-IR, H-1 and C-13 NMR, UV-Vis, and PL spectroscopy. Photophysical properties of the dyes were examined in solvents of various polarities and at different pH values. The solvent effects on the absorbance and emission spectral shift were analyzed using Lippert-Mataga, Reichardt-Dimroth and Kamlet-Taft equations. Moreover, UV-Vis absorption and emission frequencies were correlated with Hammett substituent constants applying the linear free energy relationships. DFT calculations of the investigated dyes were accomplished to determine their structural and electronic properties.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dyes and Pigments
T1  - Absorption and fluorescence spectral properties of azo dyes based on 3-amido-6-hydroxy-4-methyl-2-pyridone: Solvent and substituent effects
VL  - 175
DO  - 10.1016/j.dyepig.2019.108139
ER  - 

@article{
author = "Porobić, Slavica and Božić, Bojan and Dramićanin, Miroslav and Vitnik, Vesna and Vitnik, Željko and Marinović-Cincović, Milena and Mijin, Dušan",
year = "2020",
abstract = "A series of nine 5-(4-substituted phenylazo)-3-amido-6-hydroxy-4-methyl-2-pyridones were synthesized and characterized by FT-IR, H-1 and C-13 NMR, UV-Vis, and PL spectroscopy. Photophysical properties of the dyes were examined in solvents of various polarities and at different pH values. The solvent effects on the absorbance and emission spectral shift were analyzed using Lippert-Mataga, Reichardt-Dimroth and Kamlet-Taft equations. Moreover, UV-Vis absorption and emission frequencies were correlated with Hammett substituent constants applying the linear free energy relationships. DFT calculations of the investigated dyes were accomplished to determine their structural and electronic properties.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dyes and Pigments",
title = "Absorption and fluorescence spectral properties of azo dyes based on 3-amido-6-hydroxy-4-methyl-2-pyridone: Solvent and substituent effects",
volume = "175",
doi = "10.1016/j.dyepig.2019.108139"
}

Porobić, S., Božić, B., Dramićanin, M., Vitnik, V., Vitnik, Ž., Marinović-Cincović, M.,& Mijin, D.. (2020). Absorption and fluorescence spectral properties of azo dyes based on 3-amido-6-hydroxy-4-methyl-2-pyridone: Solvent and substituent effects. in Dyes and Pigments
Elsevier Sci Ltd, Oxford., 175.
https://doi.org/10.1016/j.dyepig.2019.108139

Porobić S, Božić B, Dramićanin M, Vitnik V, Vitnik Ž, Marinović-Cincović M, Mijin D. Absorption and fluorescence spectral properties of azo dyes based on 3-amido-6-hydroxy-4-methyl-2-pyridone: Solvent and substituent effects. in Dyes and Pigments. 2020;175.
doi:10.1016/j.dyepig.2019.108139 .

Porobić, Slavica, Božić, Bojan, Dramićanin, Miroslav, Vitnik, Vesna, Vitnik, Željko, Marinović-Cincović, Milena, Mijin, Dušan, "Absorption and fluorescence spectral properties of azo dyes based on 3-amido-6-hydroxy-4-methyl-2-pyridone: Solvent and substituent effects" in Dyes and Pigments, 175 (2020),
https://doi.org/10.1016/j.dyepig.2019.108139 . .

TY  - JOUR
AU  - Šekuljica, Nataša
AU  - Jovanović, Jelena
AU  - Jakovetić Tanasković, Sonja
AU  - Ognjanović, Nevena
AU  - Gazikalović, Ivana
AU  - Knežević-Jugović, Zorica
AU  - Mijin, Dušan
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4457
AB  - Horseradish peroxidase (HRP) is a highly specific enzyme with great potential for use in the decolorization of synthetic dyes. A comprehensive study of HRP immobilization using various techniques such as adsorption and covalent immobilization on the novel carrier Purolite (R) A109 with a special focus on enzymatic decolorization and toxicity of artificially colored wastewater. The immobilized preparations with an activity of 156.21 +/- 1.41 U g(-1) and 85.71 +/- 1.62 U g(-1) after the HRP adsorption and covalent immobilization, respectively, were obtained. Stability and reusability of the immobilized preparations were also evaluated. A noteworthy decolorization level (similar to 90%) with immobilized HRP was achieved. Phytotoxicity testing using Mung bean seeds and acute toxicity assay with Artemia salina has confirmed the applicability of the obtained immobilized preparation in industrial wastewater plants for the treatment of colored wastewater.
PB  - Wiley, Hoboken
T2  - Biotechnology Progress
T1  - Immobilization of horseradish peroxidase onto Purolite (R) A109 and its anthraquinone dye biodegradation and detoxification potential
IS  - 4
VL  - 36
DO  - 10.1002/btpr.2991
ER  - 

@article{
author = "Šekuljica, Nataša and Jovanović, Jelena and Jakovetić Tanasković, Sonja and Ognjanović, Nevena and Gazikalović, Ivana and Knežević-Jugović, Zorica and Mijin, Dušan",
year = "2020",
abstract = "Horseradish peroxidase (HRP) is a highly specific enzyme with great potential for use in the decolorization of synthetic dyes. A comprehensive study of HRP immobilization using various techniques such as adsorption and covalent immobilization on the novel carrier Purolite (R) A109 with a special focus on enzymatic decolorization and toxicity of artificially colored wastewater. The immobilized preparations with an activity of 156.21 +/- 1.41 U g(-1) and 85.71 +/- 1.62 U g(-1) after the HRP adsorption and covalent immobilization, respectively, were obtained. Stability and reusability of the immobilized preparations were also evaluated. A noteworthy decolorization level (similar to 90%) with immobilized HRP was achieved. Phytotoxicity testing using Mung bean seeds and acute toxicity assay with Artemia salina has confirmed the applicability of the obtained immobilized preparation in industrial wastewater plants for the treatment of colored wastewater.",
publisher = "Wiley, Hoboken",
journal = "Biotechnology Progress",
title = "Immobilization of horseradish peroxidase onto Purolite (R) A109 and its anthraquinone dye biodegradation and detoxification potential",
number = "4",
volume = "36",
doi = "10.1002/btpr.2991"
}

Šekuljica, N., Jovanović, J., Jakovetić Tanasković, S., Ognjanović, N., Gazikalović, I., Knežević-Jugović, Z.,& Mijin, D.. (2020). Immobilization of horseradish peroxidase onto Purolite (R) A109 and its anthraquinone dye biodegradation and detoxification potential. in Biotechnology Progress
Wiley, Hoboken., 36(4).
https://doi.org/10.1002/btpr.2991

Šekuljica N, Jovanović J, Jakovetić Tanasković S, Ognjanović N, Gazikalović I, Knežević-Jugović Z, Mijin D. Immobilization of horseradish peroxidase onto Purolite (R) A109 and its anthraquinone dye biodegradation and detoxification potential. in Biotechnology Progress. 2020;36(4).
doi:10.1002/btpr.2991 .

Šekuljica, Nataša, Jovanović, Jelena, Jakovetić Tanasković, Sonja, Ognjanović, Nevena, Gazikalović, Ivana, Knežević-Jugović, Zorica, Mijin, Dušan, "Immobilization of horseradish peroxidase onto Purolite (R) A109 and its anthraquinone dye biodegradation and detoxification potential" in Biotechnology Progress, 36, no. 4 (2020),
https://doi.org/10.1002/btpr.2991 . .

TY  - JOUR
AU  - Stupar, Stevan
AU  - Grgur, Branimir
AU  - Radišić, Marina
AU  - Onjia, Antonije
AU  - Ivanković, Negovan
AU  - Tomašević, Anđelka
AU  - Mijin, Dušan
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4508
AB  - The degradation of Acid Blue 111 anthraquinone dye has been studied by the simple electro-assisted Fenton process and the obtained results were compared to the Fenton process. Ferrous sulphate and hydrogen peroxide were used and in the electro-assisted Fenton process IrOx electrode was used as the anode. The influence of hydrogen peroxide and ferrous ion concentration, as well as pH on the processes was investigated. A second-order kinetic was established and rate constants were determined. The degradation was followed by ultraviolet-visible spectroscopy, gas and liquid chromatography-mass spectrometry analysis. Mineralization of Acid Blue 111 was confirmed by total organic carbon analysis and ion chromatography analysis. Efficiency and energy consumption of the processes were calculated. Also, phytotoxicity was studied using the Mung bean seeds. According to the obtained results, the simple electro-assisted Fenton process was much efficient in the degradation of Acid Blue 111 dye than the Fenton process.
PB  - Elsevier, Amsterdam
T2  - Journal of Water Process Engineering
T1  - Oxidative degradation of Acid Blue 111 by electro-assisted Fenton process
VL  - 36
DO  - 10.1016/j.jwpe.2020.101394
ER  - 

@article{
author = "Stupar, Stevan and Grgur, Branimir and Radišić, Marina and Onjia, Antonije and Ivanković, Negovan and Tomašević, Anđelka and Mijin, Dušan",
year = "2020",
abstract = "The degradation of Acid Blue 111 anthraquinone dye has been studied by the simple electro-assisted Fenton process and the obtained results were compared to the Fenton process. Ferrous sulphate and hydrogen peroxide were used and in the electro-assisted Fenton process IrOx electrode was used as the anode. The influence of hydrogen peroxide and ferrous ion concentration, as well as pH on the processes was investigated. A second-order kinetic was established and rate constants were determined. The degradation was followed by ultraviolet-visible spectroscopy, gas and liquid chromatography-mass spectrometry analysis. Mineralization of Acid Blue 111 was confirmed by total organic carbon analysis and ion chromatography analysis. Efficiency and energy consumption of the processes were calculated. Also, phytotoxicity was studied using the Mung bean seeds. According to the obtained results, the simple electro-assisted Fenton process was much efficient in the degradation of Acid Blue 111 dye than the Fenton process.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Water Process Engineering",
title = "Oxidative degradation of Acid Blue 111 by electro-assisted Fenton process",
volume = "36",
doi = "10.1016/j.jwpe.2020.101394"
}

Stupar, S., Grgur, B., Radišić, M., Onjia, A., Ivanković, N., Tomašević, A.,& Mijin, D.. (2020). Oxidative degradation of Acid Blue 111 by electro-assisted Fenton process. in Journal of Water Process Engineering
Elsevier, Amsterdam., 36.
https://doi.org/10.1016/j.jwpe.2020.101394

Stupar S, Grgur B, Radišić M, Onjia A, Ivanković N, Tomašević A, Mijin D. Oxidative degradation of Acid Blue 111 by electro-assisted Fenton process. in Journal of Water Process Engineering. 2020;36.
doi:10.1016/j.jwpe.2020.101394 .

Stupar, Stevan, Grgur, Branimir, Radišić, Marina, Onjia, Antonije, Ivanković, Negovan, Tomašević, Anđelka, Mijin, Dušan, "Oxidative degradation of Acid Blue 111 by electro-assisted Fenton process" in Journal of Water Process Engineering, 36 (2020),
https://doi.org/10.1016/j.jwpe.2020.101394 . .

TY  - JOUR
AU  - Kovačević, Strahinja
AU  - Karadzić-Banjac, Milica
AU  - Podunavac-Kuzmanović, Sanja
AU  - Milošević, Nataša
AU  - Curcić, Jelena
AU  - Vulić, Jelena
AU  - Seregelj, Vanja
AU  - Banjac, Nebojša
AU  - Ušćumlić, Gordana
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5885
AB  - The present study is focused on a series of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimide derivatives, as potential anticonvulsants. The retention behavior of eleven succinimide derivatives was determined by using reversed phase high performance liquid chromatography (RP-HPLC) and reversed phase high performance thin layer chromatography (RP-HPTLC). The estimated retention behavior was correlated with partition (logP) and distribution coefficients (logD). These high correlations pointed out that the determined retention parameters (logK(0) and R-M(0)) can be considered chromatographic (anisotropic) lipophilicity of the studied succinimide derivatives. The structural properties, which dominantly affect the chromatographic lipophilicity, were determined as well. The significant correlations between the chromatographic lipophilicity and plasma protein binding (PPB), Madin-Darby Canine Kidney (MDCK) cells permeability, volume of distribution (Vd) and absorption constant (Ka) indicate the strong influence of lipophilicity on pharmacokinetics of 1-aryl-3-ethyl-3-methylsuccinimide derivatives. These derivatives have also been tested applying Comprehensive Medicinal Chemistry (CMC) drug-like rules which confirmed their drug-like properties. Besides, their blood-brain penetration (BBB) ability has been estimated applying the set of Clark's rules and by using Pre-ADMET software. Regarding toxicity, it was predicted that only one compound from the set might have toxic effects by blocking the hERG potassium channel. The present study reveals which molecular features in the structure of novel succinimide derivatives could be crucial for their lipophilicity, and consequently for their pharmacokinetic properties. The results indicate that the newly synthesized series of succinimide derivatives should be further considered in design of novel anticonvulsants.
PB  - Elsevier Sci Ltd, Oxford
T2  - Computational Biology and Chemistry
T1  - Chromatographic and computational screening of anisotropic lipophilicity and pharmacokinetics of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimides
VL  - 84
DO  - 10.1016/j.compbiolchem.2019.107161
ER  - 

@article{
author = "Kovačević, Strahinja and Karadzić-Banjac, Milica and Podunavac-Kuzmanović, Sanja and Milošević, Nataša and Curcić, Jelena and Vulić, Jelena and Seregelj, Vanja and Banjac, Nebojša and Ušćumlić, Gordana",
year = "2020",
abstract = "The present study is focused on a series of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimide derivatives, as potential anticonvulsants. The retention behavior of eleven succinimide derivatives was determined by using reversed phase high performance liquid chromatography (RP-HPLC) and reversed phase high performance thin layer chromatography (RP-HPTLC). The estimated retention behavior was correlated with partition (logP) and distribution coefficients (logD). These high correlations pointed out that the determined retention parameters (logK(0) and R-M(0)) can be considered chromatographic (anisotropic) lipophilicity of the studied succinimide derivatives. The structural properties, which dominantly affect the chromatographic lipophilicity, were determined as well. The significant correlations between the chromatographic lipophilicity and plasma protein binding (PPB), Madin-Darby Canine Kidney (MDCK) cells permeability, volume of distribution (Vd) and absorption constant (Ka) indicate the strong influence of lipophilicity on pharmacokinetics of 1-aryl-3-ethyl-3-methylsuccinimide derivatives. These derivatives have also been tested applying Comprehensive Medicinal Chemistry (CMC) drug-like rules which confirmed their drug-like properties. Besides, their blood-brain penetration (BBB) ability has been estimated applying the set of Clark's rules and by using Pre-ADMET software. Regarding toxicity, it was predicted that only one compound from the set might have toxic effects by blocking the hERG potassium channel. The present study reveals which molecular features in the structure of novel succinimide derivatives could be crucial for their lipophilicity, and consequently for their pharmacokinetic properties. The results indicate that the newly synthesized series of succinimide derivatives should be further considered in design of novel anticonvulsants.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Computational Biology and Chemistry",
title = "Chromatographic and computational screening of anisotropic lipophilicity and pharmacokinetics of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimides",
volume = "84",
doi = "10.1016/j.compbiolchem.2019.107161"
}

Kovačević, S., Karadzić-Banjac, M., Podunavac-Kuzmanović, S., Milošević, N., Curcić, J., Vulić, J., Seregelj, V., Banjac, N.,& Ušćumlić, G.. (2020). Chromatographic and computational screening of anisotropic lipophilicity and pharmacokinetics of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimides. in Computational Biology and Chemistry
Elsevier Sci Ltd, Oxford., 84.
https://doi.org/10.1016/j.compbiolchem.2019.107161

Kovačević S, Karadzić-Banjac M, Podunavac-Kuzmanović S, Milošević N, Curcić J, Vulić J, Seregelj V, Banjac N, Ušćumlić G. Chromatographic and computational screening of anisotropic lipophilicity and pharmacokinetics of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimides. in Computational Biology and Chemistry. 2020;84.
doi:10.1016/j.compbiolchem.2019.107161 .

Kovačević, Strahinja, Karadzić-Banjac, Milica, Podunavac-Kuzmanović, Sanja, Milošević, Nataša, Curcić, Jelena, Vulić, Jelena, Seregelj, Vanja, Banjac, Nebojša, Ušćumlić, Gordana, "Chromatographic and computational screening of anisotropic lipophilicity and pharmacokinetics of newly synthesized 1-aryl-3-ethyl-3-methylsuccinimides" in Computational Biology and Chemistry, 84 (2020),
https://doi.org/10.1016/j.compbiolchem.2019.107161 . .

TY  - JOUR
AU  - Kovačević, Strahinja
AU  - Karadžić Banjac, Milica
AU  - Milošević, Nataša
AU  - Ćurčić, Jelena
AU  - Marjanović, Dunja
AU  - Todorović, Nemanja
AU  - Krmar, Jovana
AU  - Podunavac-Kuzmanović, Sanja
AU  - Banjac, Nebojša
AU  - Ušćumlić, Gordana
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5886
AB  - Numerous structurally different amides and imides including succinimide derivatives exhibit diverse bioactive potential. The development of new compounds requires rationalization in the design in or- der to provide structural changes that guarantee favorable physico-chemical properties, pharmacological activity and safety. In the present research, a comprehensive study with comparison of the chromato- graphic lipophilicity and other physico-chemical properties of five groups of 1-arylsuccinimide derivatives was conducted. The chemometric analysis of their physico-chemical properties was carried out by us- ing unsupervised (hierarchical cluster analysis and principal component analysis) and supervised pattern recognition methods (linear discriminant analysis), while the correlations between the in silico molecular features and chromatographic lipophilicity were examined applying linear and non-linear Quantitative Structure–Retention Relationship (QSRR) approaches. The main aim of the conducted research was to determine similarities and dissimilarities among the studied 1-arylsuccinimides, to point out the molec- ular features which have significant influence on their lipophilicity, as well as to establish high-quality QSRR models which can be used in prediction of chromatographic lipophilicity of structurally similar 1-arylsuccinimides. This study is a continuation of analysis and determination of the physico-chemical properties of 1-arylsuccinimides which could be important guidelines in further in vitro and eventually in vivo studies of their biological potential.
PB  - Elsevier B.V.
T2  - Journal of Chromatography A
T1  - Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents
VL  - 1628
DO  - 10.1016/j.chroma.2020.461439
ER  - 

@article{
author = "Kovačević, Strahinja and Karadžić Banjac, Milica and Milošević, Nataša and Ćurčić, Jelena and Marjanović, Dunja and Todorović, Nemanja and Krmar, Jovana and Podunavac-Kuzmanović, Sanja and Banjac, Nebojša and Ušćumlić, Gordana",
year = "2020",
abstract = "Numerous structurally different amides and imides including succinimide derivatives exhibit diverse bioactive potential. The development of new compounds requires rationalization in the design in or- der to provide structural changes that guarantee favorable physico-chemical properties, pharmacological activity and safety. In the present research, a comprehensive study with comparison of the chromato- graphic lipophilicity and other physico-chemical properties of five groups of 1-arylsuccinimide derivatives was conducted. The chemometric analysis of their physico-chemical properties was carried out by us- ing unsupervised (hierarchical cluster analysis and principal component analysis) and supervised pattern recognition methods (linear discriminant analysis), while the correlations between the in silico molecular features and chromatographic lipophilicity were examined applying linear and non-linear Quantitative Structure–Retention Relationship (QSRR) approaches. The main aim of the conducted research was to determine similarities and dissimilarities among the studied 1-arylsuccinimides, to point out the molec- ular features which have significant influence on their lipophilicity, as well as to establish high-quality QSRR models which can be used in prediction of chromatographic lipophilicity of structurally similar 1-arylsuccinimides. This study is a continuation of analysis and determination of the physico-chemical properties of 1-arylsuccinimides which could be important guidelines in further in vitro and eventually in vivo studies of their biological potential.",
publisher = "Elsevier B.V.",
journal = "Journal of Chromatography A",
title = "Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents",
volume = "1628",
doi = "10.1016/j.chroma.2020.461439"
}

Kovačević, S., Karadžić Banjac, M., Milošević, N., Ćurčić, J., Marjanović, D., Todorović, N., Krmar, J., Podunavac-Kuzmanović, S., Banjac, N.,& Ušćumlić, G.. (2020). Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents. in Journal of Chromatography A
Elsevier B.V.., 1628.
https://doi.org/10.1016/j.chroma.2020.461439

Kovačević S, Karadžić Banjac M, Milošević N, Ćurčić J, Marjanović D, Todorović N, Krmar J, Podunavac-Kuzmanović S, Banjac N, Ušćumlić G. Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents. in Journal of Chromatography A. 2020;1628.
doi:10.1016/j.chroma.2020.461439 .

Kovačević, Strahinja, Karadžić Banjac, Milica, Milošević, Nataša, Ćurčić, Jelena, Marjanović, Dunja, Todorović, Nemanja, Krmar, Jovana, Podunavac-Kuzmanović, Sanja, Banjac, Nebojša, Ušćumlić, Gordana, "Comparative chemometric and quantitative structure-retention relationship analysis of anisotropic lipophilicity of 1-arylsuccinimide derivatives determined in high-performance thin-layer chromatography system with aprotic solvents" in Journal of Chromatography A, 1628 (2020),
https://doi.org/10.1016/j.chroma.2020.461439 . .

TY  - JOUR
AU  - Apostolov, Suzana
AU  - Vastag, Gyongyi
AU  - Matijević, Borko M.
AU  - Đaković-Sekulić, Tatjana
AU  - Marinković, Aleksandar
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4576
AB  - Biological activity of a molecule is closely related to its lipophilicity. This significant parameter was determined for a group of potentially bioactive N-(4-phenylmonosubstituted)-2-cyanoacetamides applying thin-layer chromatography on reversed phase (RP-TLC) in mixtures of water and two organic modifiers separately, i-propanol and dioxane. The effect of the chemical structure of derivatives and the influence of the applied organic modifier on their retention were studied. The determined chromatographic retention constants, R-M(0), and the chromatographic parameter, m, of compounds were correlated with software calculated partition coefficients, log P as the standard measure of lipophilicity and with different pharmacokinetic predictors applying classical linear and multiple regression analysis. By classical linear regression analysis in both water-modifier systems only R-M(0)-log P and m-log P correlations were established (average r, 0.909 and 0.826). All studied relationships were enhanced by molecular descriptors that fulfilled the modified Lipinski's rule of five. Thereby, the performed multiple regression analysis gave better correlations (for R-M(0)-log P and m-log P average r(2), 0.994 and 0.993; for R-M(0)-pharmacokinetic parameters and m-pharmacokinetic parameters average r(2) 0.978 and 0.980). The obtained results indicate that the chromatographic parameters, R-M(0) and m determined by RP-TLC at given conditions could be used successfully for the description of lipophilicity and the evaluation of pharmacokinetic properties of N-(4-phenylmonosubstituted)-2-cyanoacetamides as potential bioactive molecules.
T2  - Journal of the Chilean Chemical Society
T1  - Thin-layer chromatography on reversed phase in the characterization of retention behaviour, lipophilicity, and pharmacokinetics of cyanoacetamide derivatives
EP  - 4660
IS  - 1
SP  - 4654
VL  - 65
DO  - 10.4067/S0717-97072020000104654
ER  - 

@article{
author = "Apostolov, Suzana and Vastag, Gyongyi and Matijević, Borko M. and Đaković-Sekulić, Tatjana and Marinković, Aleksandar",
year = "2020",
abstract = "Biological activity of a molecule is closely related to its lipophilicity. This significant parameter was determined for a group of potentially bioactive N-(4-phenylmonosubstituted)-2-cyanoacetamides applying thin-layer chromatography on reversed phase (RP-TLC) in mixtures of water and two organic modifiers separately, i-propanol and dioxane. The effect of the chemical structure of derivatives and the influence of the applied organic modifier on their retention were studied. The determined chromatographic retention constants, R-M(0), and the chromatographic parameter, m, of compounds were correlated with software calculated partition coefficients, log P as the standard measure of lipophilicity and with different pharmacokinetic predictors applying classical linear and multiple regression analysis. By classical linear regression analysis in both water-modifier systems only R-M(0)-log P and m-log P correlations were established (average r, 0.909 and 0.826). All studied relationships were enhanced by molecular descriptors that fulfilled the modified Lipinski's rule of five. Thereby, the performed multiple regression analysis gave better correlations (for R-M(0)-log P and m-log P average r(2), 0.994 and 0.993; for R-M(0)-pharmacokinetic parameters and m-pharmacokinetic parameters average r(2) 0.978 and 0.980). The obtained results indicate that the chromatographic parameters, R-M(0) and m determined by RP-TLC at given conditions could be used successfully for the description of lipophilicity and the evaluation of pharmacokinetic properties of N-(4-phenylmonosubstituted)-2-cyanoacetamides as potential bioactive molecules.",
journal = "Journal of the Chilean Chemical Society",
title = "Thin-layer chromatography on reversed phase in the characterization of retention behaviour, lipophilicity, and pharmacokinetics of cyanoacetamide derivatives",
pages = "4660-4654",
number = "1",
volume = "65",
doi = "10.4067/S0717-97072020000104654"
}

Apostolov, S., Vastag, G., Matijević, B. M., Đaković-Sekulić, T.,& Marinković, A.. (2020). Thin-layer chromatography on reversed phase in the characterization of retention behaviour, lipophilicity, and pharmacokinetics of cyanoacetamide derivatives. in Journal of the Chilean Chemical Society, 65(1), 4654-4660.
https://doi.org/10.4067/S0717-97072020000104654

Apostolov S, Vastag G, Matijević BM, Đaković-Sekulić T, Marinković A. Thin-layer chromatography on reversed phase in the characterization of retention behaviour, lipophilicity, and pharmacokinetics of cyanoacetamide derivatives. in Journal of the Chilean Chemical Society. 2020;65(1):4654-4660.
doi:10.4067/S0717-97072020000104654 .

Apostolov, Suzana, Vastag, Gyongyi, Matijević, Borko M., Đaković-Sekulić, Tatjana, Marinković, Aleksandar, "Thin-layer chromatography on reversed phase in the characterization of retention behaviour, lipophilicity, and pharmacokinetics of cyanoacetamide derivatives" in Journal of the Chilean Chemical Society, 65, no. 1 (2020):4654-4660,
https://doi.org/10.4067/S0717-97072020000104654 . .

TY  - JOUR
AU  - Tomašević, Anđelka
AU  - Marinković, Aleksandar
AU  - Mijin, Dušan
AU  - Radišić, Marina
AU  - Porobić, Slavica
AU  - Prlainović, Nevena
AU  - Gašić, Slavica
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4375
AB  - Photocatalytic degradation of the carbamate insecticide methomyl and its commercial product Lannate-90 in aqueous suspension of TiO2 and ZnO using an Osram ultra-vitalux lamp (315-400 nm) was investigated. The objective of the investigation was to study and compare the rates of photochemical degradation of the pure active compound and its formulated product in order to find out the impact of inert ingredients on degradation processes. The photo-chemical degradation of pure methomyl was found to be slower than the degradation of its commercial product Lannate-90. Photodegradation was investigated by UV-Vis spectrometry and HPLC, while mineralization was monitored using IC and TOC analyses. Light absorption capabilities of catalysts were characterized by ultraviolet-visible diffuse reflectance spectroscopy method, while the stability of catalysts was studied by infrared analyses. Degradation products of methomyl and its formulated product were identified by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) results and tentative photodegradation pathways were proposed.
PB  - Savez hemijskih inženjera, Beograd
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - A study of photocatalytic degradation of methomyl and its commercial product lannate-90
EP  - 247
IS  - 3
SP  - 237
VL  - 26
DO  - 10.2298/CICEQ190424002T
ER  - 

@article{
author = "Tomašević, Anđelka and Marinković, Aleksandar and Mijin, Dušan and Radišić, Marina and Porobić, Slavica and Prlainović, Nevena and Gašić, Slavica",
year = "2020",
abstract = "Photocatalytic degradation of the carbamate insecticide methomyl and its commercial product Lannate-90 in aqueous suspension of TiO2 and ZnO using an Osram ultra-vitalux lamp (315-400 nm) was investigated. The objective of the investigation was to study and compare the rates of photochemical degradation of the pure active compound and its formulated product in order to find out the impact of inert ingredients on degradation processes. The photo-chemical degradation of pure methomyl was found to be slower than the degradation of its commercial product Lannate-90. Photodegradation was investigated by UV-Vis spectrometry and HPLC, while mineralization was monitored using IC and TOC analyses. Light absorption capabilities of catalysts were characterized by ultraviolet-visible diffuse reflectance spectroscopy method, while the stability of catalysts was studied by infrared analyses. Degradation products of methomyl and its formulated product were identified by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) results and tentative photodegradation pathways were proposed.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "A study of photocatalytic degradation of methomyl and its commercial product lannate-90",
pages = "247-237",
number = "3",
volume = "26",
doi = "10.2298/CICEQ190424002T"
}

Tomašević, A., Marinković, A., Mijin, D., Radišić, M., Porobić, S., Prlainović, N.,& Gašić, S.. (2020). A study of photocatalytic degradation of methomyl and its commercial product lannate-90. in Chemical Industry & Chemical Engineering Quarterly
Savez hemijskih inženjera, Beograd., 26(3), 237-247.
https://doi.org/10.2298/CICEQ190424002T

Tomašević A, Marinković A, Mijin D, Radišić M, Porobić S, Prlainović N, Gašić S. A study of photocatalytic degradation of methomyl and its commercial product lannate-90. in Chemical Industry & Chemical Engineering Quarterly. 2020;26(3):237-247.
doi:10.2298/CICEQ190424002T .

Tomašević, Anđelka, Marinković, Aleksandar, Mijin, Dušan, Radišić, Marina, Porobić, Slavica, Prlainović, Nevena, Gašić, Slavica, "A study of photocatalytic degradation of methomyl and its commercial product lannate-90" in Chemical Industry & Chemical Engineering Quarterly, 26, no. 3 (2020):237-247,
https://doi.org/10.2298/CICEQ190424002T . .

TY  - JOUR
AU  - Tomašević, Anđelka
AU  - Mijin, Dušan
AU  - Radišić, Marina
AU  - Prlainović, Nevena
AU  - Cvijetić, Ilija
AU  - Kovačević, Danijela
AU  - Marinković, Aleksandar
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4480
AB  - This study describes photolysis of 1 x 10(-4) M methomyl solution in deionized water and in eleven organic solvents, both polar and nonpolar: methanol, ethanol, n-propanol, isopropanol, sec-butanol, tert-butanol, isobutanol, isopentanol, n-hexane, acetonitrile, and dichloromethane. Photolysis of methomyl at 254 nm was performed using Osram mercury lamp (6 x 8 W) by exposing to irradiation for five hours. All photolytic methomyl reactions were studied by UV/Vis spectroscopy within a wavelength range of 190 - 300 nm (Spectrum Mode), and at 233.4 nm (Quantitative Mode), while the rate of photodecomposition of methomyl was measured using UV spectroscopy and HPLC. In order to get better insight in the photolysis of methomyl, a liquid chromatography-mass spectrometry (LC-MSn) was used. The rate of methomyl photolysis was solvent-specific and the following reaction rate order was established: deionized water  gt  tert-butanol  gt  n-hexane  gt  sec-butanol  gt  ethanol  gt  isopentanol  gt  isobutanol  gt  isopropanol  gt  methanol  gt  acetonitrile  gt  dichloromethane  gt  n-propanol. Both nonspecific and specific solvent-solute interactions contribute mutually to the differences in the obtained quantum yields. Results of quantum chemical calculations, using CBS-QB3 method, provided insights into the solvent effects on both ground and excited state. The LC/MSn analysis showed the formation of several photolytic products.
PB  - Elsevier Science Sa, Lausanne
T2  - Journal of Photochemistry and Photobiology A-Chemistry
T1  - Photolysis of insecticide methomyl in various solvents: An experimental and theoretical study
VL  - 391
DO  - 10.1016/j.jphotochem.2020.112366
ER  - 

@article{
author = "Tomašević, Anđelka and Mijin, Dušan and Radišić, Marina and Prlainović, Nevena and Cvijetić, Ilija and Kovačević, Danijela and Marinković, Aleksandar",
year = "2020",
abstract = "This study describes photolysis of 1 x 10(-4) M methomyl solution in deionized water and in eleven organic solvents, both polar and nonpolar: methanol, ethanol, n-propanol, isopropanol, sec-butanol, tert-butanol, isobutanol, isopentanol, n-hexane, acetonitrile, and dichloromethane. Photolysis of methomyl at 254 nm was performed using Osram mercury lamp (6 x 8 W) by exposing to irradiation for five hours. All photolytic methomyl reactions were studied by UV/Vis spectroscopy within a wavelength range of 190 - 300 nm (Spectrum Mode), and at 233.4 nm (Quantitative Mode), while the rate of photodecomposition of methomyl was measured using UV spectroscopy and HPLC. In order to get better insight in the photolysis of methomyl, a liquid chromatography-mass spectrometry (LC-MSn) was used. The rate of methomyl photolysis was solvent-specific and the following reaction rate order was established: deionized water  gt  tert-butanol  gt  n-hexane  gt  sec-butanol  gt  ethanol  gt  isopentanol  gt  isobutanol  gt  isopropanol  gt  methanol  gt  acetonitrile  gt  dichloromethane  gt  n-propanol. Both nonspecific and specific solvent-solute interactions contribute mutually to the differences in the obtained quantum yields. Results of quantum chemical calculations, using CBS-QB3 method, provided insights into the solvent effects on both ground and excited state. The LC/MSn analysis showed the formation of several photolytic products.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Journal of Photochemistry and Photobiology A-Chemistry",
title = "Photolysis of insecticide methomyl in various solvents: An experimental and theoretical study",
volume = "391",
doi = "10.1016/j.jphotochem.2020.112366"
}

Tomašević, A., Mijin, D., Radišić, M., Prlainović, N., Cvijetić, I., Kovačević, D.,& Marinković, A.. (2020). Photolysis of insecticide methomyl in various solvents: An experimental and theoretical study. in Journal of Photochemistry and Photobiology A-Chemistry
Elsevier Science Sa, Lausanne., 391.
https://doi.org/10.1016/j.jphotochem.2020.112366

Tomašević A, Mijin D, Radišić M, Prlainović N, Cvijetić I, Kovačević D, Marinković A. Photolysis of insecticide methomyl in various solvents: An experimental and theoretical study. in Journal of Photochemistry and Photobiology A-Chemistry. 2020;391.
doi:10.1016/j.jphotochem.2020.112366 .

Tomašević, Anđelka, Mijin, Dušan, Radišić, Marina, Prlainović, Nevena, Cvijetić, Ilija, Kovačević, Danijela, Marinković, Aleksandar, "Photolysis of insecticide methomyl in various solvents: An experimental and theoretical study" in Journal of Photochemistry and Photobiology A-Chemistry, 391 (2020),
https://doi.org/10.1016/j.jphotochem.2020.112366 . .

TY  - JOUR
AU  - Crnković, Dragan
AU  - Sekulić, Zoran
AU  - Antonović, Dušan
AU  - Marinković, Aleksandar
AU  - Popović, Slađana
AU  - Nikolić, Jasmina
AU  - Drmanić, Saša
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4460
AB  - This study focussed on a comprehensive investigation on the state of pollution and identification of potential sources of contamination of some river sediments in Serbia by polycyclic aromatic hydrocarbons (PAHs), and is the basis for setting up further monitoring programs. The sediment quality of the Danube River (km 1433-845) and its tributaries in Serbia, including the Sava River (km 202-1), were analysed with respect to PAHs and total organic carbon (TOC). We found that total PAH concentration in the sediments from the Danube and its tributaries (10.0-4140 mu g kg(-1)) was lower than total PAH concentration in Sava River sediments (265.1-11272 mu g kg(-1)). Principal component analysis showed that concentrations of benzo[a]anthracene, chrysene, pyrene, fluoranthene, indeno[1,2,3- cd]pyrene, benzo[a] pyrene, benzo[b]fluoranthene and benzo[k]fluoranthene in the sediments were correlated with TOC. The diagnostic ratios anthracene/(anthracene+phenanthrene) and fluoranthene/(fluoranthene+ pyrene) were calculated to evaluate the emission sources of the PAHs. Therefore, these ratios indicated the predominantly pyrogenic source of the PAHs in the sediments. Results have also shown that river sediments in the Danube and Sava rivers and their tributaries were not recently polluted with PAHs, excluding only one location - S4, downstream of Sabac and characterized by heavily polluted sediment.
PB  - Hard, Olsztyn 5
T2  - Polish Journal of Environmental Studies
T1  - Origins of Polycyclic Aromatic Hydrocarbons in Sediments from the Danube and Sava Rivers and Their Tributaries in Serbia
EP  - 2110
IS  - 3
SP  - 2101
VL  - 29
DO  - 10.15244/pjoes/111319
ER  - 

@article{
author = "Crnković, Dragan and Sekulić, Zoran and Antonović, Dušan and Marinković, Aleksandar and Popović, Slađana and Nikolić, Jasmina and Drmanić, Saša",
year = "2020",
abstract = "This study focussed on a comprehensive investigation on the state of pollution and identification of potential sources of contamination of some river sediments in Serbia by polycyclic aromatic hydrocarbons (PAHs), and is the basis for setting up further monitoring programs. The sediment quality of the Danube River (km 1433-845) and its tributaries in Serbia, including the Sava River (km 202-1), were analysed with respect to PAHs and total organic carbon (TOC). We found that total PAH concentration in the sediments from the Danube and its tributaries (10.0-4140 mu g kg(-1)) was lower than total PAH concentration in Sava River sediments (265.1-11272 mu g kg(-1)). Principal component analysis showed that concentrations of benzo[a]anthracene, chrysene, pyrene, fluoranthene, indeno[1,2,3- cd]pyrene, benzo[a] pyrene, benzo[b]fluoranthene and benzo[k]fluoranthene in the sediments were correlated with TOC. The diagnostic ratios anthracene/(anthracene+phenanthrene) and fluoranthene/(fluoranthene+ pyrene) were calculated to evaluate the emission sources of the PAHs. Therefore, these ratios indicated the predominantly pyrogenic source of the PAHs in the sediments. Results have also shown that river sediments in the Danube and Sava rivers and their tributaries were not recently polluted with PAHs, excluding only one location - S4, downstream of Sabac and characterized by heavily polluted sediment.",
publisher = "Hard, Olsztyn 5",
journal = "Polish Journal of Environmental Studies",
title = "Origins of Polycyclic Aromatic Hydrocarbons in Sediments from the Danube and Sava Rivers and Their Tributaries in Serbia",
pages = "2110-2101",
number = "3",
volume = "29",
doi = "10.15244/pjoes/111319"
}

Crnković, D., Sekulić, Z., Antonović, D., Marinković, A., Popović, S., Nikolić, J.,& Drmanić, S.. (2020). Origins of Polycyclic Aromatic Hydrocarbons in Sediments from the Danube and Sava Rivers and Their Tributaries in Serbia. in Polish Journal of Environmental Studies
Hard, Olsztyn 5., 29(3), 2101-2110.
https://doi.org/10.15244/pjoes/111319

Crnković D, Sekulić Z, Antonović D, Marinković A, Popović S, Nikolić J, Drmanić S. Origins of Polycyclic Aromatic Hydrocarbons in Sediments from the Danube and Sava Rivers and Their Tributaries in Serbia. in Polish Journal of Environmental Studies. 2020;29(3):2101-2110.
doi:10.15244/pjoes/111319 .

Crnković, Dragan, Sekulić, Zoran, Antonović, Dušan, Marinković, Aleksandar, Popović, Slađana, Nikolić, Jasmina, Drmanić, Saša, "Origins of Polycyclic Aromatic Hydrocarbons in Sediments from the Danube and Sava Rivers and Their Tributaries in Serbia" in Polish Journal of Environmental Studies, 29, no. 3 (2020):2101-2110,
https://doi.org/10.15244/pjoes/111319 . .

TY  - JOUR
AU  - Mrđan, Gorana S.
AU  - Matijević, Borko M.
AU  - Vastag, Gyongyi
AU  - Božić, Aleksandra R.
AU  - Marinković, Aleksandar
AU  - Milčić, Miloš
AU  - Stojiljković, Ivana
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4497
AB  - Carbohydrazones are compounds that are increasingly studied due to their wide potential biological activity. Monocarbohydrazones (mCHs), as one of the carbohydrazone derivatives, so far have been poorly investigated. For a more detailed study, in this paper, eighteen compounds of monocarbohydrazones (eight known and ten newly synthesized derivatives) were synthesized and characterized using NMR and IR spectroscopy. As carbohydrazones show E/Z isomerization caused by the presence of the imino group, some of the synthesized mCHs are in the form of a mixture of these two isomers. The effects of specific and nonspecific solvent-solute interactions on the UV absorption maxima shifts were evaluated using linear free energy relationships principles, i.e., using Kamlet-Taft's and Catalan's models. For more information about interactions between dissolved substance and the surrounding medium, correlations have been made with Hansen's solubility parameters. The influence of the structure on the spectral behavior of the compounds tested was interpreted using Hammett's equation. Experimentally obtained physicochemical properties of mCHs were compared to and confirmed with computational methods that included TD-DFT calculations and MP2 geometry optimizations. Graphic abstract
PB  - Springer International Publishing Ag, Cham
T2  - Chemical Papers
T1  - Synthesis, solvent interactions and computational study of monocarbohydrazones
EP  - 2674
IS  - 8
SP  - 2653
VL  - 74
DO  - 10.1007/s11696-020-01106-4
ER  - 

@article{
author = "Mrđan, Gorana S. and Matijević, Borko M. and Vastag, Gyongyi and Božić, Aleksandra R. and Marinković, Aleksandar and Milčić, Miloš and Stojiljković, Ivana",
year = "2020",
abstract = "Carbohydrazones are compounds that are increasingly studied due to their wide potential biological activity. Monocarbohydrazones (mCHs), as one of the carbohydrazone derivatives, so far have been poorly investigated. For a more detailed study, in this paper, eighteen compounds of monocarbohydrazones (eight known and ten newly synthesized derivatives) were synthesized and characterized using NMR and IR spectroscopy. As carbohydrazones show E/Z isomerization caused by the presence of the imino group, some of the synthesized mCHs are in the form of a mixture of these two isomers. The effects of specific and nonspecific solvent-solute interactions on the UV absorption maxima shifts were evaluated using linear free energy relationships principles, i.e., using Kamlet-Taft's and Catalan's models. For more information about interactions between dissolved substance and the surrounding medium, correlations have been made with Hansen's solubility parameters. The influence of the structure on the spectral behavior of the compounds tested was interpreted using Hammett's equation. Experimentally obtained physicochemical properties of mCHs were compared to and confirmed with computational methods that included TD-DFT calculations and MP2 geometry optimizations. Graphic abstract",
publisher = "Springer International Publishing Ag, Cham",
journal = "Chemical Papers",
title = "Synthesis, solvent interactions and computational study of monocarbohydrazones",
pages = "2674-2653",
number = "8",
volume = "74",
doi = "10.1007/s11696-020-01106-4"
}

Mrđan, G. S., Matijević, B. M., Vastag, G., Božić, A. R., Marinković, A., Milčić, M.,& Stojiljković, I.. (2020). Synthesis, solvent interactions and computational study of monocarbohydrazones. in Chemical Papers
Springer International Publishing Ag, Cham., 74(8), 2653-2674.
https://doi.org/10.1007/s11696-020-01106-4

Mrđan GS, Matijević BM, Vastag G, Božić AR, Marinković A, Milčić M, Stojiljković I. Synthesis, solvent interactions and computational study of monocarbohydrazones. in Chemical Papers. 2020;74(8):2653-2674.
doi:10.1007/s11696-020-01106-4 .

Mrđan, Gorana S., Matijević, Borko M., Vastag, Gyongyi, Božić, Aleksandra R., Marinković, Aleksandar, Milčić, Miloš, Stojiljković, Ivana, "Synthesis, solvent interactions and computational study of monocarbohydrazones" in Chemical Papers, 74, no. 8 (2020):2653-2674,
https://doi.org/10.1007/s11696-020-01106-4 . .

TY  - JOUR
AU  - Božić, Aleksandra R.
AU  - Filipović, Nenad R.
AU  - Verbić, Tatjana
AU  - Milčić, Miloš
AU  - Todorović, Tamara
AU  - Cvijetić, Ilija
AU  - Klisurić, Olivera
AU  - Radišić, Marina
AU  - Marinković, Aleksandar
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4355
AB  - The substituent and solvent effect on intramolecular charge transfer (ICT) of twelve monocarbohydrazones (mCHs) were studied using experimental and theoretical methodology. The effects of specific and non-specific solvent-solute interactions on the UV-Vis absorption maxima shifts were evaluated using linear free energy relationships (LFERs) principles, i.e. using the Kamlet-Taft and Catalan models. Linear free energy relationships in the form of single substituent parameter equation (SSP) was used to analyze substituent effect on UV-Vis, NMR and pK(a) change. According to crystallographic data and quantum chemical calculations, the trans (E) form was found to be more stable. A photochromism of compounds with 2-hydroxyphenyl and 2-pyridylimino groups substituted at imine carbon atom results in E/Z isomerization due to creation of intermolecular hydrogen bond in E and Z form, respectively. Multiple stage mass spectrometry (MS-MSn) analysis was applied to define main fragmentation pathways. Furthermore, the experimental findings were interpreted with the aid of ab initio MP2/6-311 G(d,p) and time-dependent density functional (TD-DFT) methods. TD-DFT calculations were performed to quantify the efficiency of intramolecular charge transfer (ICT) with the aid of the charge-transfer distance (DCT) and the amount of transferred charge (QCT) calculation. It was found that both substituents and solvents influence electron density shift i.e. extent of conjugation, and affect ICT character in the course of excitation.
PB  - Elsevier, Amsterdam
T2  - Arabian Journal of Chemistry
T1  - A detailed experimental and computational study of monocarbohydrazones
EP  - 953
IS  - 1
SP  - 932
VL  - 13
DO  - 10.1016/j.arabjc.2017.08.010
ER  - 

@article{
author = "Božić, Aleksandra R. and Filipović, Nenad R. and Verbić, Tatjana and Milčić, Miloš and Todorović, Tamara and Cvijetić, Ilija and Klisurić, Olivera and Radišić, Marina and Marinković, Aleksandar",
year = "2020",
abstract = "The substituent and solvent effect on intramolecular charge transfer (ICT) of twelve monocarbohydrazones (mCHs) were studied using experimental and theoretical methodology. The effects of specific and non-specific solvent-solute interactions on the UV-Vis absorption maxima shifts were evaluated using linear free energy relationships (LFERs) principles, i.e. using the Kamlet-Taft and Catalan models. Linear free energy relationships in the form of single substituent parameter equation (SSP) was used to analyze substituent effect on UV-Vis, NMR and pK(a) change. According to crystallographic data and quantum chemical calculations, the trans (E) form was found to be more stable. A photochromism of compounds with 2-hydroxyphenyl and 2-pyridylimino groups substituted at imine carbon atom results in E/Z isomerization due to creation of intermolecular hydrogen bond in E and Z form, respectively. Multiple stage mass spectrometry (MS-MSn) analysis was applied to define main fragmentation pathways. Furthermore, the experimental findings were interpreted with the aid of ab initio MP2/6-311 G(d,p) and time-dependent density functional (TD-DFT) methods. TD-DFT calculations were performed to quantify the efficiency of intramolecular charge transfer (ICT) with the aid of the charge-transfer distance (DCT) and the amount of transferred charge (QCT) calculation. It was found that both substituents and solvents influence electron density shift i.e. extent of conjugation, and affect ICT character in the course of excitation.",
publisher = "Elsevier, Amsterdam",
journal = "Arabian Journal of Chemistry",
title = "A detailed experimental and computational study of monocarbohydrazones",
pages = "953-932",
number = "1",
volume = "13",
doi = "10.1016/j.arabjc.2017.08.010"
}

Božić, A. R., Filipović, N. R., Verbić, T., Milčić, M., Todorović, T., Cvijetić, I., Klisurić, O., Radišić, M.,& Marinković, A.. (2020). A detailed experimental and computational study of monocarbohydrazones. in Arabian Journal of Chemistry
Elsevier, Amsterdam., 13(1), 932-953.
https://doi.org/10.1016/j.arabjc.2017.08.010

Božić AR, Filipović NR, Verbić T, Milčić M, Todorović T, Cvijetić I, Klisurić O, Radišić M, Marinković A. A detailed experimental and computational study of monocarbohydrazones. in Arabian Journal of Chemistry. 2020;13(1):932-953.
doi:10.1016/j.arabjc.2017.08.010 .

Božić, Aleksandra R., Filipović, Nenad R., Verbić, Tatjana, Milčić, Miloš, Todorović, Tamara, Cvijetić, Ilija, Klisurić, Olivera, Radišić, Marina, Marinković, Aleksandar, "A detailed experimental and computational study of monocarbohydrazones" in Arabian Journal of Chemistry, 13, no. 1 (2020):932-953,
https://doi.org/10.1016/j.arabjc.2017.08.010 . .

TY  - JOUR
AU  - Jović, Branislav
AU  - Kordić, Branko
AU  - Miskov, Vukoslava
AU  - Tricković, Jelena
AU  - Kovacević, Marina
AU  - Petrović, Slobodan
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4349
AB  - In this study, the adsorption equilibrium and diffusivity parameters of p-nitrophenol were estimated for water containing different concentrations of secondary amides. Commercial powdered activated carbon was used as an adsorbent. The external mass transfer coefficient (k(f)), the surface diffusion coefficient (D-s) and the standard free Gibbs energy were calculated for p-nitrophenol in the presence of different secondary amide concentrations. The analysis established that there are correlations between structural parameters of amides, on the one hand, and diffusion and thermodynamic parameters for p-nitrophenol adsorption process, on the other. It was noticed that voluminous hydrophobic amides decreased the adsorption capacity of p-nitrophenol on activated carbon. On the basis of the results obtained for external mass transfer coefficients, it is assumed that amides cause the reduction of adsorption capacity of p-nitrophenol onto activated carbon by concentrating at the solid/liquid interface.
PB  - Elsevier, Amsterdam
T2  - Arabian Journal of Chemistry
T1  - Amides as a model system of low molar mass algal organic matter. Influence on the adsorption of p-nitrophenol on activated carbon
EP  - 66
IS  - 1
SP  - 59
VL  - 13
DO  - 10.1016/j.arabjc.2017.01.016
ER  - 

@article{
author = "Jović, Branislav and Kordić, Branko and Miskov, Vukoslava and Tricković, Jelena and Kovacević, Marina and Petrović, Slobodan",
year = "2020",
abstract = "In this study, the adsorption equilibrium and diffusivity parameters of p-nitrophenol were estimated for water containing different concentrations of secondary amides. Commercial powdered activated carbon was used as an adsorbent. The external mass transfer coefficient (k(f)), the surface diffusion coefficient (D-s) and the standard free Gibbs energy were calculated for p-nitrophenol in the presence of different secondary amide concentrations. The analysis established that there are correlations between structural parameters of amides, on the one hand, and diffusion and thermodynamic parameters for p-nitrophenol adsorption process, on the other. It was noticed that voluminous hydrophobic amides decreased the adsorption capacity of p-nitrophenol on activated carbon. On the basis of the results obtained for external mass transfer coefficients, it is assumed that amides cause the reduction of adsorption capacity of p-nitrophenol onto activated carbon by concentrating at the solid/liquid interface.",
publisher = "Elsevier, Amsterdam",
journal = "Arabian Journal of Chemistry",
title = "Amides as a model system of low molar mass algal organic matter. Influence on the adsorption of p-nitrophenol on activated carbon",
pages = "66-59",
number = "1",
volume = "13",
doi = "10.1016/j.arabjc.2017.01.016"
}

Jović, B., Kordić, B., Miskov, V., Tricković, J., Kovacević, M.,& Petrović, S.. (2020). Amides as a model system of low molar mass algal organic matter. Influence on the adsorption of p-nitrophenol on activated carbon. in Arabian Journal of Chemistry
Elsevier, Amsterdam., 13(1), 59-66.
https://doi.org/10.1016/j.arabjc.2017.01.016

Jović B, Kordić B, Miskov V, Tricković J, Kovacević M, Petrović S. Amides as a model system of low molar mass algal organic matter. Influence on the adsorption of p-nitrophenol on activated carbon. in Arabian Journal of Chemistry. 2020;13(1):59-66.
doi:10.1016/j.arabjc.2017.01.016 .

Jović, Branislav, Kordić, Branko, Miskov, Vukoslava, Tricković, Jelena, Kovacević, Marina, Petrović, Slobodan, "Amides as a model system of low molar mass algal organic matter. Influence on the adsorption of p-nitrophenol on activated carbon" in Arabian Journal of Chemistry, 13, no. 1 (2020):59-66,
https://doi.org/10.1016/j.arabjc.2017.01.016 . .

TY  - CONF
AU  - Valentić, Nataša
AU  - Lazić, Anita
AU  - Gak, Kristina
AU  - Trišović, Nemanja
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7463
AB  - Molecular switches, that are capable of transmitting information in a quick fashion, have an
important role in information technologies and have become key components of advanced materials.
Namely, molecular switches present small molecules or supramolecular species that can be reversibly shifted between two (or more) stable states possessing different physical features. In this way,
they enable complex systems to respond to changes in their environment including changes in light
intensity, temperature or voltage. In the present work, five pyridine-containing azo dyes were synthesized with a view to the development of novel molecular switches. The structural features of the investigated dyes were characterized by elemental analysis, FT-IR, 1H and 13C NMR spectroscopy,
while their UV/Vis absorption spectra were recorded in twenty solvents of different polarities. To
estimate the ability of the investigated dyes to interact with their environment, the effects of solvent
dipolarity/polarizability and solvent–solute hydrogen-bonding interactions on the shifts of the absorption maxima were rationalized by means of the linear solvation energy relationship concepts
proposed by Kamlet–Taft and Catalán. Based on the analysis of the structural effects on the sensitivity
of the investigated dyes to changes in the polarity of their environment, the possible applications of
these photoactive materials were further discussed.
AB  - Molekulski prekidači sposobni da brzo prenose informacije imaju važnu ulogu u informacionim
tehnologijama, a postali su i ključne komponente naprednih materijala. Naime, molekulski prekidači
predstavljaju male molekule ili supramolekulske vrste koji se mogu reverzibilno pomerati između dva
(ili više) stabilnih stanja različitih fizičkih svojstava. Na ovaj način oni omogućavaju da kompleksni
sistemi reaguju na promene u svom okruženju koje, između ostalog, obuhvataju promene u intenzitetu
svetlosti, temperature ili napona. U cilju razvoja novih molekulskih prekidača, pet azo boja koje
sadrže piridinsko jezgro je sintetisano u ovom radu i potpuno strukturno okarakterisano primenom
elementarne analize, FT-IR, 1H i 13C NMR spektroskopskih metoda. Njihovi UV/Vis apsorpcioni
spektri su određeni u dvadeset rastvarača različite polarnosti. Da bi se procenila sposobnost
proučavanih boja da uspostavljaju interakcije sa svojim okruženjem, uticaj
dipolarnosti/polarizabilnosti rastvarača i vodoničnog vezivanja između molekula rastvarača i
rastvorene supstance proučavani su metodama linearne korelacije energije solvatacije prema
Kamlet–Taftu i Katalanu. Na osnovu analize uticaja molekulske strukture na osetljivost proučavanih
boja na promene u polarnosti okruženja dalje su diskutovane moguće primene ovih fotoaktivnih
materijala.
PB  - Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku
C3  - Zbornik radova = Proceedings / 32. međunarodni kongres o procesnoj industriji, PROCESING '19, Beograd, 30. i 31. maj 2019
T1  - SOLVATOCHROMIC INVESTIGATION OF PYRIDINE-CONTAINING AZO DYES AS BUILDING BLOCKS FOR MOLECULAR SWITCHES
T1  - PROUČAVANJE SOLVATOHROMNIH SVOJSTAVA PIRIDINSKIH AZO BOJA KAO GRADIVNIH JEDINICA ZA MOLEKULSKE PREKIDAČE
EP  - 57
SP  - 53
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7463
ER  - 

@conference{
author = "Valentić, Nataša and Lazić, Anita and Gak, Kristina and Trišović, Nemanja",
year = "2019",
abstract = "Molecular switches, that are capable of transmitting information in a quick fashion, have an
important role in information technologies and have become key components of advanced materials.
Namely, molecular switches present small molecules or supramolecular species that can be reversibly shifted between two (or more) stable states possessing different physical features. In this way,
they enable complex systems to respond to changes in their environment including changes in light
intensity, temperature or voltage. In the present work, five pyridine-containing azo dyes were synthesized with a view to the development of novel molecular switches. The structural features of the investigated dyes were characterized by elemental analysis, FT-IR, 1H and 13C NMR spectroscopy,
while their UV/Vis absorption spectra were recorded in twenty solvents of different polarities. To
estimate the ability of the investigated dyes to interact with their environment, the effects of solvent
dipolarity/polarizability and solvent–solute hydrogen-bonding interactions on the shifts of the absorption maxima were rationalized by means of the linear solvation energy relationship concepts
proposed by Kamlet–Taft and Catalán. Based on the analysis of the structural effects on the sensitivity
of the investigated dyes to changes in the polarity of their environment, the possible applications of
these photoactive materials were further discussed., Molekulski prekidači sposobni da brzo prenose informacije imaju važnu ulogu u informacionim
tehnologijama, a postali su i ključne komponente naprednih materijala. Naime, molekulski prekidači
predstavljaju male molekule ili supramolekulske vrste koji se mogu reverzibilno pomerati između dva
(ili više) stabilnih stanja različitih fizičkih svojstava. Na ovaj način oni omogućavaju da kompleksni
sistemi reaguju na promene u svom okruženju koje, između ostalog, obuhvataju promene u intenzitetu
svetlosti, temperature ili napona. U cilju razvoja novih molekulskih prekidača, pet azo boja koje
sadrže piridinsko jezgro je sintetisano u ovom radu i potpuno strukturno okarakterisano primenom
elementarne analize, FT-IR, 1H i 13C NMR spektroskopskih metoda. Njihovi UV/Vis apsorpcioni
spektri su određeni u dvadeset rastvarača različite polarnosti. Da bi se procenila sposobnost
proučavanih boja da uspostavljaju interakcije sa svojim okruženjem, uticaj
dipolarnosti/polarizabilnosti rastvarača i vodoničnog vezivanja između molekula rastvarača i
rastvorene supstance proučavani su metodama linearne korelacije energije solvatacije prema
Kamlet–Taftu i Katalanu. Na osnovu analize uticaja molekulske strukture na osetljivost proučavanih
boja na promene u polarnosti okruženja dalje su diskutovane moguće primene ovih fotoaktivnih
materijala.",
publisher = "Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku",
journal = "Zbornik radova = Proceedings / 32. međunarodni kongres o procesnoj industriji, PROCESING '19, Beograd, 30. i 31. maj 2019",
title = "SOLVATOCHROMIC INVESTIGATION OF PYRIDINE-CONTAINING AZO DYES AS BUILDING BLOCKS FOR MOLECULAR SWITCHES, PROUČAVANJE SOLVATOHROMNIH SVOJSTAVA PIRIDINSKIH AZO BOJA KAO GRADIVNIH JEDINICA ZA MOLEKULSKE PREKIDAČE",
pages = "57-53",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7463"
}

Valentić, N., Lazić, A., Gak, K.,& Trišović, N.. (2019). SOLVATOCHROMIC INVESTIGATION OF PYRIDINE-CONTAINING AZO DYES AS BUILDING BLOCKS FOR MOLECULAR SWITCHES. in Zbornik radova = Proceedings / 32. međunarodni kongres o procesnoj industriji, PROCESING '19, Beograd, 30. i 31. maj 2019
Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku., 53-57.
https://hdl.handle.net/21.15107/rcub_technorep_7463

Valentić N, Lazić A, Gak K, Trišović N. SOLVATOCHROMIC INVESTIGATION OF PYRIDINE-CONTAINING AZO DYES AS BUILDING BLOCKS FOR MOLECULAR SWITCHES. in Zbornik radova = Proceedings / 32. međunarodni kongres o procesnoj industriji, PROCESING '19, Beograd, 30. i 31. maj 2019. 2019;:53-57.
https://hdl.handle.net/21.15107/rcub_technorep_7463 .

Valentić, Nataša, Lazić, Anita, Gak, Kristina, Trišović, Nemanja, "SOLVATOCHROMIC INVESTIGATION OF PYRIDINE-CONTAINING AZO DYES AS BUILDING BLOCKS FOR MOLECULAR SWITCHES" in Zbornik radova = Proceedings / 32. međunarodni kongres o procesnoj industriji, PROCESING '19, Beograd, 30. i 31. maj 2019 (2019):53-57,
https://hdl.handle.net/21.15107/rcub_technorep_7463 .

TY  - CONF
AU  - Tot, Kristina A.
AU  - Lazić, Anita M.
AU  - Đaković-Sekulić, Tatjana Lj.
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7465
AB  - Spirohidantoins represent a pharmacologically important class of compounds. Many of
them display activities against a wide range of biological targets1
. A recent study shows
that a wide range of biological activities of spirohydantoin derivatives strongly depends
upon their structure. Hence it is important to understand their properties, particularly the
properties of newly synthesized derivatives. One of the most important properties for
biological activity is lipophilicity. Lipophilicity is responsible for pharmacokinetics, and
hence important for further development of potentially active compounds. The aim of
this study is to determine the chromatographic retention parameter of the new
synthesized spirohydantoin derivatives as a measure of their lipophilicity.
Chromatographic retention parameters of investigated compounds have been determined
by reversed-phase thin-layer chromatography on C-18 modified silica gel. Mobile
phases were two-component mixtures of water and aprotic organic solvents (i.e.
acetonitrile, acetone, dioxane, and tetrahydrofuran).
Quantitative structure-retention relationship2 (QSRR) was used for assessment of
relationships between chromatographic retention parameters, RM
0
, and calculated
partition coefficients of the molecule, log P. For the calculation of log P and additional
molecular descriptors were used several software packages (Dragon and ChemDraw) in
addition to online internet modules Molinspiration (https://www.molinspiration.com/)
and ADMETlab (http://admet.scbdd.com/).
PB  - Belgrade : Serbian Chemical Society
C3  - Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019
T1  - QSRR prediction of the chromatographic retention behaviour of spirohydantoin derivatives
SP  - 118
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7465
ER  - 

@conference{
author = "Tot, Kristina A. and Lazić, Anita M. and Đaković-Sekulić, Tatjana Lj.",
year = "2019",
abstract = "Spirohidantoins represent a pharmacologically important class of compounds. Many of
them display activities against a wide range of biological targets1
. A recent study shows
that a wide range of biological activities of spirohydantoin derivatives strongly depends
upon their structure. Hence it is important to understand their properties, particularly the
properties of newly synthesized derivatives. One of the most important properties for
biological activity is lipophilicity. Lipophilicity is responsible for pharmacokinetics, and
hence important for further development of potentially active compounds. The aim of
this study is to determine the chromatographic retention parameter of the new
synthesized spirohydantoin derivatives as a measure of their lipophilicity.
Chromatographic retention parameters of investigated compounds have been determined
by reversed-phase thin-layer chromatography on C-18 modified silica gel. Mobile
phases were two-component mixtures of water and aprotic organic solvents (i.e.
acetonitrile, acetone, dioxane, and tetrahydrofuran).
Quantitative structure-retention relationship2 (QSRR) was used for assessment of
relationships between chromatographic retention parameters, RM
0
, and calculated
partition coefficients of the molecule, log P. For the calculation of log P and additional
molecular descriptors were used several software packages (Dragon and ChemDraw) in
addition to online internet modules Molinspiration (https://www.molinspiration.com/)
and ADMETlab (http://admet.scbdd.com/).",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019",
title = "QSRR prediction of the chromatographic retention behaviour of spirohydantoin derivatives",
pages = "118",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7465"
}

Tot, K. A., Lazić, A. M.,& Đaković-Sekulić, T. Lj.. (2019). QSRR prediction of the chromatographic retention behaviour of spirohydantoin derivatives. in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019
Belgrade : Serbian Chemical Society., 118.
https://hdl.handle.net/21.15107/rcub_technorep_7465

Tot KA, Lazić AM, Đaković-Sekulić TL. QSRR prediction of the chromatographic retention behaviour of spirohydantoin derivatives. in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019. 2019;:118.
https://hdl.handle.net/21.15107/rcub_technorep_7465 .

Tot, Kristina A., Lazić, Anita M., Đaković-Sekulić, Tatjana Lj., "QSRR prediction of the chromatographic retention behaviour of spirohydantoin derivatives" in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019 (2019):118,
https://hdl.handle.net/21.15107/rcub_technorep_7465 .

TY  - JOUR
AU  - Lović, Jelena
AU  - Avramov-Ivić, Milka
AU  - Božić, Bojan
AU  - Lađarević, Jelena
AU  - Mijin, Dušan
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4182
AB  - The inclusion complexes of the selected, potentially biologically active, succinimides with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD) were prepared. The formation of the inclusion complexes of the investigated monophenyl and diphenyl succinimide derivatives was confirmed using attenuated total reflection (ATR) study. Their electrochemical behavior was examined by cyclic voltammetry (CV) and square wave voltammetry (SWV) in 0.05 M NaHCO3 on a gold electrode. The stability constants for compound 1 were determined by cyclic voltammetry and calculated as K-beta CD = 350.87 M-1 and K-HP(beta CD) = 250.67 M-1. The SWV measurements reveal well defined peak at potential E-p = similar to 60 mV and the higher currents at E-p for both inclusion complex of the succinimides compared to the free compounds. The impact of chlorine atom in the phenyl moiety of succinimide derivatives on the activity in electro oxidation reaction is presented. Among the studied succinimides, according to SWV measurements, the most active is the monophenyl succinimide derivative (compound 1) in complex with beta CD. The difference of peak current of compound 1 + beta CD compared to compound 1 + HP beta CD and free compound is 6.3 and 35.2 mu A cm(-2), respectively.
PB  - Slovensko Kemijsko Drustvo, Ljubljana
T2  - Acta Chimica Slovenica
T1  - Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin
EP  - 189
IS  - 1
SP  - 182
VL  - 66
DO  - 10.17344/acsi.2018.4767
ER  - 

@article{
author = "Lović, Jelena and Avramov-Ivić, Milka and Božić, Bojan and Lađarević, Jelena and Mijin, Dušan",
year = "2019",
abstract = "The inclusion complexes of the selected, potentially biologically active, succinimides with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD) were prepared. The formation of the inclusion complexes of the investigated monophenyl and diphenyl succinimide derivatives was confirmed using attenuated total reflection (ATR) study. Their electrochemical behavior was examined by cyclic voltammetry (CV) and square wave voltammetry (SWV) in 0.05 M NaHCO3 on a gold electrode. The stability constants for compound 1 were determined by cyclic voltammetry and calculated as K-beta CD = 350.87 M-1 and K-HP(beta CD) = 250.67 M-1. The SWV measurements reveal well defined peak at potential E-p = similar to 60 mV and the higher currents at E-p for both inclusion complex of the succinimides compared to the free compounds. The impact of chlorine atom in the phenyl moiety of succinimide derivatives on the activity in electro oxidation reaction is presented. Among the studied succinimides, according to SWV measurements, the most active is the monophenyl succinimide derivative (compound 1) in complex with beta CD. The difference of peak current of compound 1 + beta CD compared to compound 1 + HP beta CD and free compound is 6.3 and 35.2 mu A cm(-2), respectively.",
publisher = "Slovensko Kemijsko Drustvo, Ljubljana",
journal = "Acta Chimica Slovenica",
title = "Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin",
pages = "189-182",
number = "1",
volume = "66",
doi = "10.17344/acsi.2018.4767"
}

Lović, J., Avramov-Ivić, M., Božić, B., Lađarević, J.,& Mijin, D.. (2019). Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin. in Acta Chimica Slovenica
Slovensko Kemijsko Drustvo, Ljubljana., 66(1), 182-189.
https://doi.org/10.17344/acsi.2018.4767

Lović J, Avramov-Ivić M, Božić B, Lađarević J, Mijin D. Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin. in Acta Chimica Slovenica. 2019;66(1):182-189.
doi:10.17344/acsi.2018.4767 .

Lović, Jelena, Avramov-Ivić, Milka, Božić, Bojan, Lađarević, Jelena, Mijin, Dušan, "Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin" in Acta Chimica Slovenica, 66, no. 1 (2019):182-189,
https://doi.org/10.17344/acsi.2018.4767 . .

TY  - JOUR
AU  - Petković-Cvetković, Jelena
AU  - Božić, Bojan
AU  - Banjac, Nebojša
AU  - Lađarević, Jelena
AU  - Vitnik, Vesna
AU  - Vitnik, Željko
AU  - Valentić, Nataša
AU  - Ušćumlić, Gordana
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4267
AB  - Novel succinimide derivatives were synthesized from 3-methyl-3-phenylsuccinic acid and substituted anilines under solvent-free conditions by using microwave irradiation. All obtained compounds were characterized by ultraviolet (UV), Fourier-transform infrared (FT-IR), H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopy as well as by elemental analysis. The influence of the substituent electronic effects on spectroscopic data was analyzed by applying the Hammett equation. Moreover, a detailed interpretation and comparison of experimentally obtained and theoretically calculated FT-IR, UV and NMR spectra was performed. Density functional theory (DFT) calculated data of the investigated succinimides were obtained and analyzed in order to determine their structural, spectroscopic and electronic properties. Furthermore, ADMET factor profiling and in-silico prediction of potential biological activities of novel succinimide derivatives have been performed.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska industrija
T1  - Spectroscopic and quantum chemical elucidation of newly synthesized 1-aryl-3-methyl-3-phenylpyrrolidine-2,5-diones as potential anticonvulsant agents
EP  - 137
IS  - 2
SP  - 125
VL  - 73
DO  - 10.2298/HEMIND190214011P
ER  - 

@article{
author = "Petković-Cvetković, Jelena and Božić, Bojan and Banjac, Nebojša and Lađarević, Jelena and Vitnik, Vesna and Vitnik, Željko and Valentić, Nataša and Ušćumlić, Gordana",
year = "2019",
abstract = "Novel succinimide derivatives were synthesized from 3-methyl-3-phenylsuccinic acid and substituted anilines under solvent-free conditions by using microwave irradiation. All obtained compounds were characterized by ultraviolet (UV), Fourier-transform infrared (FT-IR), H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopy as well as by elemental analysis. The influence of the substituent electronic effects on spectroscopic data was analyzed by applying the Hammett equation. Moreover, a detailed interpretation and comparison of experimentally obtained and theoretically calculated FT-IR, UV and NMR spectra was performed. Density functional theory (DFT) calculated data of the investigated succinimides were obtained and analyzed in order to determine their structural, spectroscopic and electronic properties. Furthermore, ADMET factor profiling and in-silico prediction of potential biological activities of novel succinimide derivatives have been performed.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska industrija",
title = "Spectroscopic and quantum chemical elucidation of newly synthesized 1-aryl-3-methyl-3-phenylpyrrolidine-2,5-diones as potential anticonvulsant agents",
pages = "137-125",
number = "2",
volume = "73",
doi = "10.2298/HEMIND190214011P"
}

Petković-Cvetković, J., Božić, B., Banjac, N., Lađarević, J., Vitnik, V., Vitnik, Ž., Valentić, N.,& Ušćumlić, G.. (2019). Spectroscopic and quantum chemical elucidation of newly synthesized 1-aryl-3-methyl-3-phenylpyrrolidine-2,5-diones as potential anticonvulsant agents. in Hemijska industrija
Savez hemijskih inženjera, Beograd., 73(2), 125-137.
https://doi.org/10.2298/HEMIND190214011P

Petković-Cvetković J, Božić B, Banjac N, Lađarević J, Vitnik V, Vitnik Ž, Valentić N, Ušćumlić G. Spectroscopic and quantum chemical elucidation of newly synthesized 1-aryl-3-methyl-3-phenylpyrrolidine-2,5-diones as potential anticonvulsant agents. in Hemijska industrija. 2019;73(2):125-137.
doi:10.2298/HEMIND190214011P .

Petković-Cvetković, Jelena, Božić, Bojan, Banjac, Nebojša, Lađarević, Jelena, Vitnik, Vesna, Vitnik, Željko, Valentić, Nataša, Ušćumlić, Gordana, "Spectroscopic and quantum chemical elucidation of newly synthesized 1-aryl-3-methyl-3-phenylpyrrolidine-2,5-diones as potential anticonvulsant agents" in Hemijska industrija, 73, no. 2 (2019):125-137,
https://doi.org/10.2298/HEMIND190214011P . .

TY  - JOUR
AU  - Petković-Cvetković, Jelena
AU  - Božić, Bojan
AU  - Banjac, Nebojša
AU  - Petrović, Jovana
AU  - Soković, Marina
AU  - Vitnik, Vesna
AU  - Vitnik, Željko
AU  - Ušćumlić, Gordana
AU  - Valentić, Nataša
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4309
AB  - In the present study, twelve new 1-aryl-3-ethyl-3-methylpyrrolidine-2,5-diones were synthesized and their structures were characterized by FT-IR, H-1 NMR, C-13 NMR spectroscopy and elemental analysis. In the final step of synthetic rout, condensation between corresponding succinic acid and substituted anilines has been improved using the microwave irradiation. Significantly higher yields compared to conventional condensation have been observed. The preliminary biological results indicated that some of the synthesized compounds showed promising in vitro antifungal activities towards several test fungi. 1-(4-Bromophenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione (8) exhibited significant in vitro inhibitory activities against broad spectra of fungus, and on the basis of obtained data, the investigated bromo derivative has to be observed as novel potential fungicide. The density functional theory (DFT) calculations have been performed in order to study the structure-activity relationship (SAR) of the investigated molecules. In order to prediction of the chemical activity of the molecule, the molecular electrostatic potential (MEP) map was analyzed for the optimized geometry of 1-phenyl-3-ethyl-3-methylpyrrolidine-2,5-dione (4) and 1-(4-bromophenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione (8).
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Molecular Structure
T1  - Synthesis, antimicrobial activity and quantum chemical investigation of novel succinimide derivatives
EP  - 156
SP  - 148
VL  - 1181
DO  - 10.1016/j.molstruc.2018.12.083
ER  - 

@article{
author = "Petković-Cvetković, Jelena and Božić, Bojan and Banjac, Nebojša and Petrović, Jovana and Soković, Marina and Vitnik, Vesna and Vitnik, Željko and Ušćumlić, Gordana and Valentić, Nataša",
year = "2019",
abstract = "In the present study, twelve new 1-aryl-3-ethyl-3-methylpyrrolidine-2,5-diones were synthesized and their structures were characterized by FT-IR, H-1 NMR, C-13 NMR spectroscopy and elemental analysis. In the final step of synthetic rout, condensation between corresponding succinic acid and substituted anilines has been improved using the microwave irradiation. Significantly higher yields compared to conventional condensation have been observed. The preliminary biological results indicated that some of the synthesized compounds showed promising in vitro antifungal activities towards several test fungi. 1-(4-Bromophenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione (8) exhibited significant in vitro inhibitory activities against broad spectra of fungus, and on the basis of obtained data, the investigated bromo derivative has to be observed as novel potential fungicide. The density functional theory (DFT) calculations have been performed in order to study the structure-activity relationship (SAR) of the investigated molecules. In order to prediction of the chemical activity of the molecule, the molecular electrostatic potential (MEP) map was analyzed for the optimized geometry of 1-phenyl-3-ethyl-3-methylpyrrolidine-2,5-dione (4) and 1-(4-bromophenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione (8).",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Molecular Structure",
title = "Synthesis, antimicrobial activity and quantum chemical investigation of novel succinimide derivatives",
pages = "156-148",
volume = "1181",
doi = "10.1016/j.molstruc.2018.12.083"
}

Petković-Cvetković, J., Božić, B., Banjac, N., Petrović, J., Soković, M., Vitnik, V., Vitnik, Ž., Ušćumlić, G.,& Valentić, N.. (2019). Synthesis, antimicrobial activity and quantum chemical investigation of novel succinimide derivatives. in Journal of Molecular Structure
Elsevier Science Bv, Amsterdam., 1181, 148-156.
https://doi.org/10.1016/j.molstruc.2018.12.083

Petković-Cvetković J, Božić B, Banjac N, Petrović J, Soković M, Vitnik V, Vitnik Ž, Ušćumlić G, Valentić N. Synthesis, antimicrobial activity and quantum chemical investigation of novel succinimide derivatives. in Journal of Molecular Structure. 2019;1181:148-156.
doi:10.1016/j.molstruc.2018.12.083 .

Petković-Cvetković, Jelena, Božić, Bojan, Banjac, Nebojša, Petrović, Jovana, Soković, Marina, Vitnik, Vesna, Vitnik, Željko, Ušćumlić, Gordana, Valentić, Nataša, "Synthesis, antimicrobial activity and quantum chemical investigation of novel succinimide derivatives" in Journal of Molecular Structure, 1181 (2019):148-156,
https://doi.org/10.1016/j.molstruc.2018.12.083 . .

TY  - JOUR
AU  - Lađarević, Jelena
AU  - Božić, Bojan
AU  - Matović, Luka
AU  - Božić-Nedeljković, Biljana
AU  - Mijin, Dušan
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4312
AB  - A series of novel 5-(4-substituted phenylazo)-1-carboxymethyl-3-cyano-6-hydroxy-4-methyl-2-pyridones had been synthesized and characterized. The study includes spectral determination of the possible tautomeric forms and the intramolecular hydrogen bonding pattern. The influence of the bifurcated intramolecular hydrogen bond on the spectral properties has been discussed. The dyes exist in hydrazone form both solid state and in most of the employed solvents. Equilibrium between hydrazone and anion forms has been studied in N,N-dimethylformamide and N,N-dimethylacetamide. For quantitative elucidation of solvent effects on UV-Vis absorption maxima, a linear solvation energy relationship concept has been employed using Kamlet-Taft's and Catalan's equations. Antioxidative activity of the synthesized dyes has been chemically tested and two derivatives (hydroxy and methoxy) are qualified as promising antioxidant molecules.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dyes and Pigments
T1  - Role of the bifurcated intramolecular hydrogen bond on the physicochemical profile of the novel azo pyridone dyes
EP  - 572
SP  - 562
VL  - 162
DO  - 10.1016/j.dyepig.2018.10.058
ER  - 

@article{
author = "Lađarević, Jelena and Božić, Bojan and Matović, Luka and Božić-Nedeljković, Biljana and Mijin, Dušan",
year = "2019",
abstract = "A series of novel 5-(4-substituted phenylazo)-1-carboxymethyl-3-cyano-6-hydroxy-4-methyl-2-pyridones had been synthesized and characterized. The study includes spectral determination of the possible tautomeric forms and the intramolecular hydrogen bonding pattern. The influence of the bifurcated intramolecular hydrogen bond on the spectral properties has been discussed. The dyes exist in hydrazone form both solid state and in most of the employed solvents. Equilibrium between hydrazone and anion forms has been studied in N,N-dimethylformamide and N,N-dimethylacetamide. For quantitative elucidation of solvent effects on UV-Vis absorption maxima, a linear solvation energy relationship concept has been employed using Kamlet-Taft's and Catalan's equations. Antioxidative activity of the synthesized dyes has been chemically tested and two derivatives (hydroxy and methoxy) are qualified as promising antioxidant molecules.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dyes and Pigments",
title = "Role of the bifurcated intramolecular hydrogen bond on the physicochemical profile of the novel azo pyridone dyes",
pages = "572-562",
volume = "162",
doi = "10.1016/j.dyepig.2018.10.058"
}

Lađarević, J., Božić, B., Matović, L., Božić-Nedeljković, B.,& Mijin, D.. (2019). Role of the bifurcated intramolecular hydrogen bond on the physicochemical profile of the novel azo pyridone dyes. in Dyes and Pigments
Elsevier Sci Ltd, Oxford., 162, 562-572.
https://doi.org/10.1016/j.dyepig.2018.10.058

Lađarević J, Božić B, Matović L, Božić-Nedeljković B, Mijin D. Role of the bifurcated intramolecular hydrogen bond on the physicochemical profile of the novel azo pyridone dyes. in Dyes and Pigments. 2019;162:562-572.
doi:10.1016/j.dyepig.2018.10.058 .

Lađarević, Jelena, Božić, Bojan, Matović, Luka, Božić-Nedeljković, Biljana, Mijin, Dušan, "Role of the bifurcated intramolecular hydrogen bond on the physicochemical profile of the novel azo pyridone dyes" in Dyes and Pigments, 162 (2019):562-572,
https://doi.org/10.1016/j.dyepig.2018.10.058 . .

TY  - JOUR
AU  - Lazić, Anita M.
AU  - Radovanović, Lidija D.
AU  - Božić, Bojan Đ.
AU  - Božić Nedeljković, Biljana Đ.
AU  - Vitnik, Vesna D.
AU  - Vitnik, Željko J.
AU  - Rogan, Jelena R.
AU  - Valentić, Nataša V.
AU  - Ušćumlić, Gordana S.
AU  - Trišović, Nemanja P.
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4324
AB  - Two series of cycloalkanespiro-5-hydantoins, namely cyclo-hexanespiro-5-hydantoins and cycloheptanespiro-5-hydantoins with a 4-substituted benzyl or a 2-(4-substituted phenyl)-2-oxoethyl group at N3 position, were synthesized and their effects on proliferation of human colon (HCT-116), leukemia (K562) and breast (MDA-MB-231) cancer cell lines were tested. For comparison, we also described the 5,5-diphenylhydantoin analogues. The structural features of the investigated compounds were characterized by elemental analysis, FT-IR, UV-Vis, H-1 and C-13 NMR spectroscopy and X-ray crystallography. Regarding their structure-activity relationships, it was shown that the substitution on the benzyl moiety with the methoxy, chloro or bromo group potentiated the antiproliferative activity relative to the parent compounds, while an increase in the size of the cycloalkyl group resulted mostly in a decrease of the antiproliferative activity. The single crystal X-ray analysis revealed the existence of dimers and chains formed by the N-H center dot center dot center dot center dot O hydrogen bonds. The analysis of the molecular descriptors of Lipinski demonstrated that all investigated compounds obeyed the rule of five. To further understand their geometry and electronic structure, OFT calculations with B3LYP method using 6-311++G(d,p) basic set were performed. In this context, the UV-Vis spectra of the investigated compounds were analyzed in detail, whereby the predicted absorption spectra from DFT calculation matched the experimentally obtained ones, with a good correlation. The interesting physico-chemical and pharmacologically relevant properties of the investigated compounds warrant their further investigation.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Molecular Structure
T1  - Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety
EP  - 62
SP  - 48
VL  - 1180
DO  - 10.1016/j.molstruc.2018.11.071
ER  - 

@article{
author = "Lazić, Anita M. and Radovanović, Lidija D. and Božić, Bojan Đ. and Božić Nedeljković, Biljana Đ. and Vitnik, Vesna D. and Vitnik, Željko J. and Rogan, Jelena R. and Valentić, Nataša V. and Ušćumlić, Gordana S. and Trišović, Nemanja P.",
year = "2019",
abstract = "Two series of cycloalkanespiro-5-hydantoins, namely cyclo-hexanespiro-5-hydantoins and cycloheptanespiro-5-hydantoins with a 4-substituted benzyl or a 2-(4-substituted phenyl)-2-oxoethyl group at N3 position, were synthesized and their effects on proliferation of human colon (HCT-116), leukemia (K562) and breast (MDA-MB-231) cancer cell lines were tested. For comparison, we also described the 5,5-diphenylhydantoin analogues. The structural features of the investigated compounds were characterized by elemental analysis, FT-IR, UV-Vis, H-1 and C-13 NMR spectroscopy and X-ray crystallography. Regarding their structure-activity relationships, it was shown that the substitution on the benzyl moiety with the methoxy, chloro or bromo group potentiated the antiproliferative activity relative to the parent compounds, while an increase in the size of the cycloalkyl group resulted mostly in a decrease of the antiproliferative activity. The single crystal X-ray analysis revealed the existence of dimers and chains formed by the N-H center dot center dot center dot center dot O hydrogen bonds. The analysis of the molecular descriptors of Lipinski demonstrated that all investigated compounds obeyed the rule of five. To further understand their geometry and electronic structure, OFT calculations with B3LYP method using 6-311++G(d,p) basic set were performed. In this context, the UV-Vis spectra of the investigated compounds were analyzed in detail, whereby the predicted absorption spectra from DFT calculation matched the experimentally obtained ones, with a good correlation. The interesting physico-chemical and pharmacologically relevant properties of the investigated compounds warrant their further investigation.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Molecular Structure",
title = "Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety",
pages = "62-48",
volume = "1180",
doi = "10.1016/j.molstruc.2018.11.071"
}

Lazić, A. M., Radovanović, L. D., Božić, B. Đ., Božić Nedeljković, B. Đ., Vitnik, V. D., Vitnik, Ž. J., Rogan, J. R., Valentić, N. V., Ušćumlić, G. S.,& Trišović, N. P.. (2019). Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety. in Journal of Molecular Structure
Elsevier Science Bv, Amsterdam., 1180, 48-62.
https://doi.org/10.1016/j.molstruc.2018.11.071

Lazić AM, Radovanović LD, Božić BĐ, Božić Nedeljković BĐ, Vitnik VD, Vitnik ŽJ, Rogan JR, Valentić NV, Ušćumlić GS, Trišović NP. Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety. in Journal of Molecular Structure. 2019;1180:48-62.
doi:10.1016/j.molstruc.2018.11.071 .

Lazić, Anita M., Radovanović, Lidija D., Božić, Bojan Đ., Božić Nedeljković, Biljana Đ., Vitnik, Vesna D., Vitnik, Željko J., Rogan, Jelena R., Valentić, Nataša V., Ušćumlić, Gordana S., Trišović, Nemanja P., "Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety" in Journal of Molecular Structure, 1180 (2019):48-62,
https://doi.org/10.1016/j.molstruc.2018.11.071 . .

TY  - JOUR
AU  - Lazić, Anita M.
AU  - Radovanović, Lidija D.
AU  - Božić, Bojan Đ.
AU  - Božić Nedeljković, Biljana Đ.
AU  - Vitnik, Vesna D.
AU  - Vitnik, Željko J.
AU  - Rogan, Jelena R.
AU  - Valentić, Nataša V.
AU  - Ušćumlić, Gordana S.
AU  - Trišović, Nemanja P.
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5038
AB  - Two series of cycloalkanespiro-5-hydantoins, namely cyclohexanespiro-5-hydantoins and cycloheptanespiro-5-hydantoins with a 4-substituted benzyl or a 2-(4-substituted phenyl)-2-oxoethyl group at N3 position, were synthesized and their effects on proliferation of human colon (HCT-116), leukemia (K562) and breast (MDA-MB-231) cancer cell lines were tested. For comparison, we also described the 5,5-diphenylhydantoin analogues. The structural features of the investigated compounds were characterized by elemental analysis, FT-IR, UV–Vis, 1 H and 13 C NMR spectroscopy and X-ray crystallography. Regarding their structure–activity relationships, it was shown that the substitution on the benzyl moiety with the methoxy, chloro or bromo group potentiated the antiproliferative activity relative to the parent compounds, while an increase in the size of the cycloalkyl group resulted mostly in a decrease of the antiproliferative activity. The single crystal X-ray analysis revealed the existence of dimers and chains formed by the N–H⋯O hydrogen bonds. The analysis of the molecular descriptors of Lipinski demonstrated that all investigated compounds obeyed the rule of five. To further understand their geometry and electronic structure, DFT calculations with B3LYP method using 6-311++G(d,p) basic set were performed. In this context, the UV–Vis spectra of the investigated compounds were analyzed in detail, whereby the predicted absorption spectra from DFT calculation matched the experimentally obtained ones, with a good correlation. The interesting physico-chemical and pharmacologically relevant properties of the investigated compounds warrant their further investigation.
PB  - Elsevier B.V.
T2  - Journal of Molecular Structure
T1  - Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety
EP  - 62
SP  - 48
VL  - 1180
DO  - 10.1016/j.molstruc.2018.11.071
ER  - 

@article{
author = "Lazić, Anita M. and Radovanović, Lidija D. and Božić, Bojan Đ. and Božić Nedeljković, Biljana Đ. and Vitnik, Vesna D. and Vitnik, Željko J. and Rogan, Jelena R. and Valentić, Nataša V. and Ušćumlić, Gordana S. and Trišović, Nemanja P.",
year = "2019",
abstract = "Two series of cycloalkanespiro-5-hydantoins, namely cyclohexanespiro-5-hydantoins and cycloheptanespiro-5-hydantoins with a 4-substituted benzyl or a 2-(4-substituted phenyl)-2-oxoethyl group at N3 position, were synthesized and their effects on proliferation of human colon (HCT-116), leukemia (K562) and breast (MDA-MB-231) cancer cell lines were tested. For comparison, we also described the 5,5-diphenylhydantoin analogues. The structural features of the investigated compounds were characterized by elemental analysis, FT-IR, UV–Vis, 1 H and 13 C NMR spectroscopy and X-ray crystallography. Regarding their structure–activity relationships, it was shown that the substitution on the benzyl moiety with the methoxy, chloro or bromo group potentiated the antiproliferative activity relative to the parent compounds, while an increase in the size of the cycloalkyl group resulted mostly in a decrease of the antiproliferative activity. The single crystal X-ray analysis revealed the existence of dimers and chains formed by the N–H⋯O hydrogen bonds. The analysis of the molecular descriptors of Lipinski demonstrated that all investigated compounds obeyed the rule of five. To further understand their geometry and electronic structure, DFT calculations with B3LYP method using 6-311++G(d,p) basic set were performed. In this context, the UV–Vis spectra of the investigated compounds were analyzed in detail, whereby the predicted absorption spectra from DFT calculation matched the experimentally obtained ones, with a good correlation. The interesting physico-chemical and pharmacologically relevant properties of the investigated compounds warrant their further investigation.",
publisher = "Elsevier B.V.",
journal = "Journal of Molecular Structure",
title = "Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety",
pages = "62-48",
volume = "1180",
doi = "10.1016/j.molstruc.2018.11.071"
}

Lazić, A. M., Radovanović, L. D., Božić, B. Đ., Božić Nedeljković, B. Đ., Vitnik, V. D., Vitnik, Ž. J., Rogan, J. R., Valentić, N. V., Ušćumlić, G. S.,& Trišović, N. P.. (2019). Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety. in Journal of Molecular Structure
Elsevier B.V.., 1180, 48-62.
https://doi.org/10.1016/j.molstruc.2018.11.071

Lazić AM, Radovanović LD, Božić BĐ, Božić Nedeljković BĐ, Vitnik VD, Vitnik ŽJ, Rogan JR, Valentić NV, Ušćumlić GS, Trišović NP. Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety. in Journal of Molecular Structure. 2019;1180:48-62.
doi:10.1016/j.molstruc.2018.11.071 .

Lazić, Anita M., Radovanović, Lidija D., Božić, Bojan Đ., Božić Nedeljković, Biljana Đ., Vitnik, Vesna D., Vitnik, Željko J., Rogan, Jelena R., Valentić, Nataša V., Ušćumlić, Gordana S., Trišović, Nemanja P., "Synthesis, structural characterization, DFT calculations and antiproliferative evaluation of novel spirohydantoin derivatives containing a substituted benzyl moiety" in Journal of Molecular Structure, 1180 (2019):48-62,
https://doi.org/10.1016/j.molstruc.2018.11.071 . .

TY  - CONF
AU  - Karić, Nataša
AU  - Gržetić, Jelena
AU  - Kovačević, Tihomir
AU  - Marinković, Aleksandar
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6121
AB  - The starch oxidation involves oxidation of primary or secondary hydroxyl to carbonyl
or carboxyl groups, whereas the number of these groups indicates the level of oxidation.
Oxidized starch is used as surface sizing agent and coating binder in the paper industry,
or as polymeric filler that increases the polymer degradability. The main objective of the
presented study is to investigate the effects of various parameters on the oxidation
process of the wheat starch, using dry method (Fig. 1). These parameters include
oxidizer concentration, catalyst type (iron(II) sulphate, copper(II) sulphate and
copper(II) citrate), presence of plasticizers/modifiers (ricinoleic acid, (R-(Z))-12-
hydroxy-9-octadecenoic acid, RA) and diizopropyl tartarate ((dipropan-2-yl 2,3-
dihydroxybutanedioate, DIPT) and reaction temperature (20 and 80 °C). The obtained
results suggest that higher values of carbonyl and carboxyl groups lead to an increase of
swelling capacity and solubility, while viscosity decreases, compared to the native wheat
starch. The analysis of FTIR spectra, especially region of carbonyl/carboxyl groups
absorption, reveals high impact of process parameters on the oxidation degree and band
structure. The morphology of native and oxidized starches, investigated by the SEM
method, shows that after oxidation the surface of the starch particles becomes smoother
then for the native starch, with aggregation of small and large-sized granules.
C3  - 7th Conference of the Young Chemists of Serbia
T1  - Preparation and characterization of oxidized wheat starch with hydrogen peroxide as an environmentally friendly oxidant
SP  - 144
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6121
ER  - 

@conference{
author = "Karić, Nataša and Gržetić, Jelena and Kovačević, Tihomir and Marinković, Aleksandar",
year = "2019",
abstract = "The starch oxidation involves oxidation of primary or secondary hydroxyl to carbonyl
or carboxyl groups, whereas the number of these groups indicates the level of oxidation.
Oxidized starch is used as surface sizing agent and coating binder in the paper industry,
or as polymeric filler that increases the polymer degradability. The main objective of the
presented study is to investigate the effects of various parameters on the oxidation
process of the wheat starch, using dry method (Fig. 1). These parameters include
oxidizer concentration, catalyst type (iron(II) sulphate, copper(II) sulphate and
copper(II) citrate), presence of plasticizers/modifiers (ricinoleic acid, (R-(Z))-12-
hydroxy-9-octadecenoic acid, RA) and diizopropyl tartarate ((dipropan-2-yl 2,3-
dihydroxybutanedioate, DIPT) and reaction temperature (20 and 80 °C). The obtained
results suggest that higher values of carbonyl and carboxyl groups lead to an increase of
swelling capacity and solubility, while viscosity decreases, compared to the native wheat
starch. The analysis of FTIR spectra, especially region of carbonyl/carboxyl groups
absorption, reveals high impact of process parameters on the oxidation degree and band
structure. The morphology of native and oxidized starches, investigated by the SEM
method, shows that after oxidation the surface of the starch particles becomes smoother
then for the native starch, with aggregation of small and large-sized granules.",
journal = "7th Conference of the Young Chemists of Serbia",
title = "Preparation and characterization of oxidized wheat starch with hydrogen peroxide as an environmentally friendly oxidant",
pages = "144",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6121"
}

Karić, N., Gržetić, J., Kovačević, T.,& Marinković, A.. (2019). Preparation and characterization of oxidized wheat starch with hydrogen peroxide as an environmentally friendly oxidant. in 7th Conference of the Young Chemists of Serbia, 144.
https://hdl.handle.net/21.15107/rcub_technorep_6121

Karić N, Gržetić J, Kovačević T, Marinković A. Preparation and characterization of oxidized wheat starch with hydrogen peroxide as an environmentally friendly oxidant. in 7th Conference of the Young Chemists of Serbia. 2019;:144.
https://hdl.handle.net/21.15107/rcub_technorep_6121 .

Karić, Nataša, Gržetić, Jelena, Kovačević, Tihomir, Marinković, Aleksandar, "Preparation and characterization of oxidized wheat starch with hydrogen peroxide as an environmentally friendly oxidant" in 7th Conference of the Young Chemists of Serbia (2019):144,
https://hdl.handle.net/21.15107/rcub_technorep_6121 .

TY  - CONF
AU  - Tomašević, Anđelka
AU  - Marinković, Aleksandar
AU  - Mijin, Dušan
AU  - Prlainović, Nevena
AU  - Gašić, Slavica
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7316
PB  - Ljubljana : Slovenian Chemical Society
C3  - EAAOP-6 : 6th European Conference on Environmental Applications of Advanced Oxidation Processes : 26-30 June 2019, Portorož - Portorose, Slovenia : book of abstracts
T1  - Photocatalytic degradation of methomyl and Lannate-90
EP  - 388
SP  - 387
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7316
ER  - 

@conference{
author = "Tomašević, Anđelka and Marinković, Aleksandar and Mijin, Dušan and Prlainović, Nevena and Gašić, Slavica",
year = "2019",
publisher = "Ljubljana : Slovenian Chemical Society",
journal = "EAAOP-6 : 6th European Conference on Environmental Applications of Advanced Oxidation Processes : 26-30 June 2019, Portorož - Portorose, Slovenia : book of abstracts",
title = "Photocatalytic degradation of methomyl and Lannate-90",
pages = "388-387",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7316"
}

Tomašević, A., Marinković, A., Mijin, D., Prlainović, N.,& Gašić, S.. (2019). Photocatalytic degradation of methomyl and Lannate-90. in EAAOP-6 : 6th European Conference on Environmental Applications of Advanced Oxidation Processes : 26-30 June 2019, Portorož - Portorose, Slovenia : book of abstracts
Ljubljana : Slovenian Chemical Society., 387-388.
https://hdl.handle.net/21.15107/rcub_technorep_7316

Tomašević A, Marinković A, Mijin D, Prlainović N, Gašić S. Photocatalytic degradation of methomyl and Lannate-90. in EAAOP-6 : 6th European Conference on Environmental Applications of Advanced Oxidation Processes : 26-30 June 2019, Portorož - Portorose, Slovenia : book of abstracts. 2019;:387-388.
https://hdl.handle.net/21.15107/rcub_technorep_7316 .

Tomašević, Anđelka, Marinković, Aleksandar, Mijin, Dušan, Prlainović, Nevena, Gašić, Slavica, "Photocatalytic degradation of methomyl and Lannate-90" in EAAOP-6 : 6th European Conference on Environmental Applications of Advanced Oxidation Processes : 26-30 June 2019, Portorož - Portorose, Slovenia : book of abstracts (2019):387-388,
https://hdl.handle.net/21.15107/rcub_technorep_7316 .

TY  - CONF
AU  - Tomašević, Anđelka
AU  - Mijin, Dušan
AU  - Gašić, Slavica
AU  - Prlainović, Nevena
AU  - Marinković, Aleksandar
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7317
PB  - Leskovac : Faculty of Technology
C3  - Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019
T1  - Photocatalysis of carbofuran: comparison of ZnO and TiO2 efficiency
SP  - 92
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7317
ER  - 

@conference{
author = "Tomašević, Anđelka and Mijin, Dušan and Gašić, Slavica and Prlainović, Nevena and Marinković, Aleksandar",
year = "2019",
publisher = "Leskovac : Faculty of Technology",
journal = "Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019",
title = "Photocatalysis of carbofuran: comparison of ZnO and TiO2 efficiency",
pages = "92",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7317"
}

Tomašević, A., Mijin, D., Gašić, S., Prlainović, N.,& Marinković, A.. (2019). Photocatalysis of carbofuran: comparison of ZnO and TiO2 efficiency. in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019
Leskovac : Faculty of Technology., 92.
https://hdl.handle.net/21.15107/rcub_technorep_7317

Tomašević A, Mijin D, Gašić S, Prlainović N, Marinković A. Photocatalysis of carbofuran: comparison of ZnO and TiO2 efficiency. in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019. 2019;:92.
https://hdl.handle.net/21.15107/rcub_technorep_7317 .

Tomašević, Anđelka, Mijin, Dušan, Gašić, Slavica, Prlainović, Nevena, Marinković, Aleksandar, "Photocatalysis of carbofuran: comparison of ZnO and TiO2 efficiency" in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019 (2019):92,
https://hdl.handle.net/21.15107/rcub_technorep_7317 .

TY  - CONF
AU  - Tomašević, Anđelka
AU  - Petrović, Slobodan
AU  - Mijin, Dušan
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7307
PB  - Leskovac : Faculty of Technology
C3  - Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019
T1  - Photochemical processes for removal of carbamate pesticides from water
EP  - 34
SP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7307
ER  - 

@conference{
author = "Tomašević, Anđelka and Petrović, Slobodan and Mijin, Dušan",
year = "2019",
publisher = "Leskovac : Faculty of Technology",
journal = "Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019",
title = "Photochemical processes for removal of carbamate pesticides from water",
pages = "34-33",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7307"
}

Tomašević, A., Petrović, S.,& Mijin, D.. (2019). Photochemical processes for removal of carbamate pesticides from water. in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019
Leskovac : Faculty of Technology., 33-34.
https://hdl.handle.net/21.15107/rcub_technorep_7307

Tomašević A, Petrović S, Mijin D. Photochemical processes for removal of carbamate pesticides from water. in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019. 2019;:33-34.
https://hdl.handle.net/21.15107/rcub_technorep_7307 .

Tomašević, Anđelka, Petrović, Slobodan, Mijin, Dušan, "Photochemical processes for removal of carbamate pesticides from water" in Book of abstracts / 13th Symposium with international participation "Novel Technologies and Economic Development" Leskovac, October, 18-19, 2019 (2019):33-34,
https://hdl.handle.net/21.15107/rcub_technorep_7307 .

TY  - CHAP
AU  - Šekuljica, Nataša
AU  - Prlainović, Nevena
AU  - Knežević-Jugović, Zorica
AU  - Mijin, Dušan
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6269
AB  - Horseradish peroxidase is a heme-containing plant enzyme (HRP; EC 1.11.1.7) with a wide range of biotechnological and medical applications. In combination with hydrogen peroxide (H2O2) as an oxidant HRP can be used in the oxidation of various substrates (e.g. considered as toxic, muthagenic, recalcitrant and carcinogenic compounds with harmful impact on human health and ecosystems and main textile industry problem when it comes to environment pollution with wastewaters. Traditional methods are inefficient, and in recent years, with a view to preserving the environment, the scientific community turns to the application of enzymes as the main catalysts in the removal of synthetic dyes. Based on the data available in the literature, HRP proved to be an enzyme with a high potential for the application of synthetic dyes removal by the mechanism of polymerization or ring opening. In this chapter well-studied enzyme is described with the focus on its promising use in colored wastewater treatment. C. I. Acid Violet 109 (AV 109) was used as a model dye in order to examine the feasibility of HRP application in removal of anthraquinone class of synthetic dyes. The reaction conditions were optimized in terms of dye, enzyme and H2O2 concentration as well as temperature and pH influence. It was established that the dye removal shows good agreement with two substrate ping-pong mechanism with substrate inhibition. The industrial application of this enzyme requires the economic feasibility. Accordingly, an expensive commercial preparation HRP was replaced with partially purified enzyme isolated from horseradish root which showed high efficiency in model dye removal. The next step towards the industrial application of this enzyme was the immobilization of various techniques (adsorption, covalent immobilization, cross-linked aggregates) to various carriers such as kaolin and the synthetic carrier Purolite® A109. Improvement in storage and operational stability after immobilization was confirmed and immobilized preparations were applied in different bioreactor configurations, batch and packed bed. HRP catalyzed removal of synthetic dyes appeared to be promising technique dye to high efficiency in dye removal and phytotoxicity and acute toxicity decrease, measured by Mung bean seeds and A. salina assays.
PB  - New York: Nova Science Publishers, Inc.
T2  - Horseradish peroxidase: Structure, Functions and Applications
T1  - Removal of Synthetic Dyes from Wastewaters Using Horseradish Peroxidase
EP  - 168
SP  - 112
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6269
ER  - 

@inbook{
author = "Šekuljica, Nataša and Prlainović, Nevena and Knežević-Jugović, Zorica and Mijin, Dušan",
year = "2019",
abstract = "Horseradish peroxidase is a heme-containing plant enzyme (HRP; EC 1.11.1.7) with a wide range of biotechnological and medical applications. In combination with hydrogen peroxide (H2O2) as an oxidant HRP can be used in the oxidation of various substrates (e.g. considered as toxic, muthagenic, recalcitrant and carcinogenic compounds with harmful impact on human health and ecosystems and main textile industry problem when it comes to environment pollution with wastewaters. Traditional methods are inefficient, and in recent years, with a view to preserving the environment, the scientific community turns to the application of enzymes as the main catalysts in the removal of synthetic dyes. Based on the data available in the literature, HRP proved to be an enzyme with a high potential for the application of synthetic dyes removal by the mechanism of polymerization or ring opening. In this chapter well-studied enzyme is described with the focus on its promising use in colored wastewater treatment. C. I. Acid Violet 109 (AV 109) was used as a model dye in order to examine the feasibility of HRP application in removal of anthraquinone class of synthetic dyes. The reaction conditions were optimized in terms of dye, enzyme and H2O2 concentration as well as temperature and pH influence. It was established that the dye removal shows good agreement with two substrate ping-pong mechanism with substrate inhibition. The industrial application of this enzyme requires the economic feasibility. Accordingly, an expensive commercial preparation HRP was replaced with partially purified enzyme isolated from horseradish root which showed high efficiency in model dye removal. The next step towards the industrial application of this enzyme was the immobilization of various techniques (adsorption, covalent immobilization, cross-linked aggregates) to various carriers such as kaolin and the synthetic carrier Purolite® A109. Improvement in storage and operational stability after immobilization was confirmed and immobilized preparations were applied in different bioreactor configurations, batch and packed bed. HRP catalyzed removal of synthetic dyes appeared to be promising technique dye to high efficiency in dye removal and phytotoxicity and acute toxicity decrease, measured by Mung bean seeds and A. salina assays.",
publisher = "New York: Nova Science Publishers, Inc.",
journal = "Horseradish peroxidase: Structure, Functions and Applications",
booktitle = "Removal of Synthetic Dyes from Wastewaters Using Horseradish Peroxidase",
pages = "168-112",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6269"
}

Šekuljica, N., Prlainović, N., Knežević-Jugović, Z.,& Mijin, D.. (2019). Removal of Synthetic Dyes from Wastewaters Using Horseradish Peroxidase. in Horseradish peroxidase: Structure, Functions and Applications
New York: Nova Science Publishers, Inc.., 112-168.
https://hdl.handle.net/21.15107/rcub_technorep_6269

Šekuljica N, Prlainović N, Knežević-Jugović Z, Mijin D. Removal of Synthetic Dyes from Wastewaters Using Horseradish Peroxidase. in Horseradish peroxidase: Structure, Functions and Applications. 2019;:112-168.
https://hdl.handle.net/21.15107/rcub_technorep_6269 .

Šekuljica, Nataša, Prlainović, Nevena, Knežević-Jugović, Zorica, Mijin, Dušan, "Removal of Synthetic Dyes from Wastewaters Using Horseradish Peroxidase" in Horseradish peroxidase: Structure, Functions and Applications (2019):112-168,
https://hdl.handle.net/21.15107/rcub_technorep_6269 .