TY  - JOUR
AU  - Marković, Miljana S.
AU  - Bošković-Vragolović, Nevenka
AU  - Ristić, Mihailo S.
AU  - Pavićević, Vladimir
AU  - Veljković, Vlada B.
AU  - Milojević, Svetomir
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3646
AB  - This paper deals with fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation (HD) and simultaneous hydrodistillation and rectification (SHDR) at atmospheric pressure. A rectification column was filled with the NORMAG packing A type and had 36 theoretical stages. In the present study, higher essential oil yield was obtained by HD (1.34 mass %) than by SHDR (1.17 mass %). However, mass fraction distributions of monoterpene hydrocarbons (MHs), oxygenated monoterpenes (OMs) and sesquiterpene hydrocarbons (SHs), observed for the two separation methods, differed from each other. In the SHDR process increased contents of high volatile components (predominantly MHs) were obtained in the initial fractions as well as increased contents of low volatile components (dominantly SHs) in the last fractions. Also, this method increased the separation degree of OMs.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska industrija
T1  - Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification
EP  - 477
IS  - 6
SP  - 471
VL  - 71
DO  - 10.2298/HEMIND161204009M
ER  - 

@article{
author = "Marković, Miljana S. and Bošković-Vragolović, Nevenka and Ristić, Mihailo S. and Pavićević, Vladimir and Veljković, Vlada B. and Milojević, Svetomir",
year = "2017",
abstract = "This paper deals with fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation (HD) and simultaneous hydrodistillation and rectification (SHDR) at atmospheric pressure. A rectification column was filled with the NORMAG packing A type and had 36 theoretical stages. In the present study, higher essential oil yield was obtained by HD (1.34 mass %) than by SHDR (1.17 mass %). However, mass fraction distributions of monoterpene hydrocarbons (MHs), oxygenated monoterpenes (OMs) and sesquiterpene hydrocarbons (SHs), observed for the two separation methods, differed from each other. In the SHDR process increased contents of high volatile components (predominantly MHs) were obtained in the initial fractions as well as increased contents of low volatile components (dominantly SHs) in the last fractions. Also, this method increased the separation degree of OMs.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska industrija",
title = "Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification",
pages = "477-471",
number = "6",
volume = "71",
doi = "10.2298/HEMIND161204009M"
}

Marković, M. S., Bošković-Vragolović, N., Ristić, M. S., Pavićević, V., Veljković, V. B.,& Milojević, S.. (2017). Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification. in Hemijska industrija
Savez hemijskih inženjera, Beograd., 71(6), 471-477.
https://doi.org/10.2298/HEMIND161204009M

Marković MS, Bošković-Vragolović N, Ristić MS, Pavićević V, Veljković VB, Milojević S. Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification. in Hemijska industrija. 2017;71(6):471-477.
doi:10.2298/HEMIND161204009M .

Marković, Miljana S., Bošković-Vragolović, Nevenka, Ristić, Mihailo S., Pavićević, Vladimir, Veljković, Vlada B., Milojević, Svetomir, "Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification" in Hemijska industrija, 71, no. 6 (2017):471-477,
https://doi.org/10.2298/HEMIND161204009M . .

TY  - JOUR
AU  - Petrović, Nada V.
AU  - Petrović, Slobodan S.
AU  - Džamić, Ana M.
AU  - Ćirić, Ana D.
AU  - Ristić, Mihailo S.
AU  - Milovanović, Stoja
AU  - Petrović, Slobodan
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3394
AB  - The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts
EP  - 125
SP  - 117
VL  - 110
DO  - 10.1016/j.supflu.2016.01.001
ER  - 

@article{
author = "Petrović, Nada V. and Petrović, Slobodan S. and Džamić, Ana M. and Ćirić, Ana D. and Ristić, Mihailo S. and Milovanović, Stoja and Petrović, Slobodan",
year = "2016",
abstract = "The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts",
pages = "125-117",
volume = "110",
doi = "10.1016/j.supflu.2016.01.001"
}

Petrović, N. V., Petrović, S. S., Džamić, A. M., Ćirić, A. D., Ristić, M. S., Milovanović, S.,& Petrović, S.. (2016). Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 110, 117-125.
https://doi.org/10.1016/j.supflu.2016.01.001

Petrović NV, Petrović SS, Džamić AM, Ćirić AD, Ristić MS, Milovanović S, Petrović S. Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids. 2016;110:117-125.
doi:10.1016/j.supflu.2016.01.001 .

Petrović, Nada V., Petrović, Slobodan S., Džamić, Ana M., Ćirić, Ana D., Ristić, Mihailo S., Milovanović, Stoja, Petrović, Slobodan, "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts" in Journal of Supercritical Fluids, 110 (2016):117-125,
https://doi.org/10.1016/j.supflu.2016.01.001 . .

TY  - JOUR
AU  - Pavićević, Vladimir
AU  - Marković, Miljana S.
AU  - Milojević, Svetomir
AU  - Ristić, Mihailo S.
AU  - Povrenović, Dragan
AU  - Veljković, Vlada B.
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3460
AB  - BACKGROUNDMicrowave-assisted hydrodistillation (MAHD) has widely been used to isolate essential oil from various plant materials, but it has not been applied yet to extract essential oil from juniper berries. The main goals of the present work were to establish a model describing the extraction kinetics and the chemical composition of the essential oil obtained. RESULTSA lower final essential oil yield from juniper berries was obtained by MAHD than by conventional hydrodistillation (HD). No significant differences in chemical compositions of the essential oils extracted by the two techniques were observed. The mechanism of both processes was the same and included fast (washing) and slow (diffusion) distillation of essential oil that occurred simultaneously. CONCLUSIONThe kinetic model involving simultaneous washing and diffusion of essential oil was verified for various plant materials (areal parts of savory and thyme, fennel seeds and juniper berries) for both MAHD and HD that indicated its general importance. For the first time, the kinetic models of MAHD and HD were compared. Knowledge of the juniper berry essential oil yield and the extraction kinetics is of importance from the technological and economics points of view, while the chemical composition determines its use.
PB  - Wiley, Hoboken
T2  - Journal of Chemical Technology and Biotechnology
T1  - Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition
EP  - 891
IS  - 4
SP  - 883
VL  - 91
DO  - 10.1002/jctb.4653
ER  - 

@article{
author = "Pavićević, Vladimir and Marković, Miljana S. and Milojević, Svetomir and Ristić, Mihailo S. and Povrenović, Dragan and Veljković, Vlada B.",
year = "2016",
abstract = "BACKGROUNDMicrowave-assisted hydrodistillation (MAHD) has widely been used to isolate essential oil from various plant materials, but it has not been applied yet to extract essential oil from juniper berries. The main goals of the present work were to establish a model describing the extraction kinetics and the chemical composition of the essential oil obtained. RESULTSA lower final essential oil yield from juniper berries was obtained by MAHD than by conventional hydrodistillation (HD). No significant differences in chemical compositions of the essential oils extracted by the two techniques were observed. The mechanism of both processes was the same and included fast (washing) and slow (diffusion) distillation of essential oil that occurred simultaneously. CONCLUSIONThe kinetic model involving simultaneous washing and diffusion of essential oil was verified for various plant materials (areal parts of savory and thyme, fennel seeds and juniper berries) for both MAHD and HD that indicated its general importance. For the first time, the kinetic models of MAHD and HD were compared. Knowledge of the juniper berry essential oil yield and the extraction kinetics is of importance from the technological and economics points of view, while the chemical composition determines its use.",
publisher = "Wiley, Hoboken",
journal = "Journal of Chemical Technology and Biotechnology",
title = "Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition",
pages = "891-883",
number = "4",
volume = "91",
doi = "10.1002/jctb.4653"
}

Pavićević, V., Marković, M. S., Milojević, S., Ristić, M. S., Povrenović, D.,& Veljković, V. B.. (2016). Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition. in Journal of Chemical Technology and Biotechnology
Wiley, Hoboken., 91(4), 883-891.
https://doi.org/10.1002/jctb.4653

Pavićević V, Marković MS, Milojević S, Ristić MS, Povrenović D, Veljković VB. Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition. in Journal of Chemical Technology and Biotechnology. 2016;91(4):883-891.
doi:10.1002/jctb.4653 .

Pavićević, Vladimir, Marković, Miljana S., Milojević, Svetomir, Ristić, Mihailo S., Povrenović, Dragan, Veljković, Vlada B., "Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition" in Journal of Chemical Technology and Biotechnology, 91, no. 4 (2016):883-891,
https://doi.org/10.1002/jctb.4653 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Kesić, Željka
AU  - Lukić, Ivana
AU  - Milovanović, Stoja
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2498
AB  - Yield and composition of curry flower (Helichrysum italicum) and sage leaves (Salvia officinalis) extract obtained by supercritical CO2 extraction (SFE) at 15 MPa and 40 degrees C were analyzed and compared to composition of curry flowers and sage essential oil isolated by hydrodistillation. Furthermore, the SFE performed using a mixture of curry flowers and sage plant and SFE of mixture of curry flowers and essential oil of sage were analyzed, too. It was shown that the average selectivity of monoterpenes and some individual sesquiterpenes and diterpenes present in pure sage or pure curry extract were significantly changed when mixture of these plants was used for SFE. The goal of SFE realized with mixture of curry flowers and sage essential oil was to explain effect of essential oil used as co-solvent changing the solubility of different compounds or characteristic group of terpenes in supercritical CO2. Increased extraction of heavier compounds from curry flower which is actually not present in pure essential oil of sage was also detected. The pseudo-kinetic model was proposed and corresponding parameters which define the rate of extraction were determined and compared to the parameters obtained according to Sovova's model usually used in literature for predicting yield of SFE from different plants.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical fluid extraction of curry flowers, sage leaves, and their mixture
EP  - 12
SP  - 1
VL  - 84
DO  - 10.1016/j.supflu.2013.09.003
ER  - 

@article{
author = "Maksimović, Svetolik and Kesić, Željka and Lukić, Ivana and Milovanović, Stoja and Ristić, Mihailo S. and Skala, Dejan",
year = "2013",
abstract = "Yield and composition of curry flower (Helichrysum italicum) and sage leaves (Salvia officinalis) extract obtained by supercritical CO2 extraction (SFE) at 15 MPa and 40 degrees C were analyzed and compared to composition of curry flowers and sage essential oil isolated by hydrodistillation. Furthermore, the SFE performed using a mixture of curry flowers and sage plant and SFE of mixture of curry flowers and essential oil of sage were analyzed, too. It was shown that the average selectivity of monoterpenes and some individual sesquiterpenes and diterpenes present in pure sage or pure curry extract were significantly changed when mixture of these plants was used for SFE. The goal of SFE realized with mixture of curry flowers and sage essential oil was to explain effect of essential oil used as co-solvent changing the solubility of different compounds or characteristic group of terpenes in supercritical CO2. Increased extraction of heavier compounds from curry flower which is actually not present in pure essential oil of sage was also detected. The pseudo-kinetic model was proposed and corresponding parameters which define the rate of extraction were determined and compared to the parameters obtained according to Sovova's model usually used in literature for predicting yield of SFE from different plants.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical fluid extraction of curry flowers, sage leaves, and their mixture",
pages = "12-1",
volume = "84",
doi = "10.1016/j.supflu.2013.09.003"
}

Maksimović, S., Kesić, Ž., Lukić, I., Milovanović, S., Ristić, M. S.,& Skala, D.. (2013). Supercritical fluid extraction of curry flowers, sage leaves, and their mixture. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 84, 1-12.
https://doi.org/10.1016/j.supflu.2013.09.003

Maksimović S, Kesić Ž, Lukić I, Milovanović S, Ristić MS, Skala D. Supercritical fluid extraction of curry flowers, sage leaves, and their mixture. in Journal of Supercritical Fluids. 2013;84:1-12.
doi:10.1016/j.supflu.2013.09.003 .

Maksimović, Svetolik, Kesić, Željka, Lukić, Ivana, Milovanović, Stoja, Ristić, Mihailo S., Skala, Dejan, "Supercritical fluid extraction of curry flowers, sage leaves, and their mixture" in Journal of Supercritical Fluids, 84 (2013):1-12,
https://doi.org/10.1016/j.supflu.2013.09.003 . .

TY  - JOUR
AU  - Žižović, Irena
AU  - Ivanović, Jasna
AU  - Mišić, Dušan
AU  - Stamenić, Marko
AU  - Đorđević, Sofija
AU  - Kukić-Marković, Jelena
AU  - Petrović, Slobodan
PY  - 2012
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2123
AB  - The number of cases of fatal infections in humans and animals caused by multiresistant and panresistant bacterial strains has been dramatically increased over the past 10 years on almost every continent. Therefore, implementation of newer technologies in order to develop processes for isolation of substances with strong antibacterial activities from natural sources is of increasing interest. In this study, advantage of high pressure processing and supercritical fluid extraction with carbon dioxide in isolation of active principles from lichen Usnea barbata L was presented. Supercritical extraction showed extremely higher selectivity toward usnic acid compared to the conventional techniques tested. In order to simulate the process and estimate mass transfer coefficients, the new mathematical model of Sovova (2011) was applied. Supercritical extract obtained at 40 C and 30 MPa showed stronger antibacterial activity against the most of tested strains compared to pure usnic acid and extracts obtained using ethanol as a solvent. Further, supercritical extract with lower usnic acid content expressed stronger antibacterial activity against the majority of tested strains including MRSA strains compared to the pure usnic acid and the supercritical extract with the higher usnic acid content. The same extract was far more effective than ampicillin against Streptococcus uberis, all tested Enterococcus faecalis, MRSA and MRSA ATCC 33591. Against few tested strains, the supercritical extract was superior to erythromycin and penicillin as well. These findings justified possible benefits of inclusion of supercritical extracts into pharmaceutical and cosmetic formulations. Applied mathematical model described the SFE process with high accuracy.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - SFE as a superior technique for isolation of extracts with strong antibacterial activities from lichen Usnea barbata L.
EP  - 14
SP  - 7
VL  - 72
DO  - 10.1016/j.supflu.2012.07.018
ER  - 

@article{
author = "Žižović, Irena and Ivanović, Jasna and Mišić, Dušan and Stamenić, Marko and Đorđević, Sofija and Kukić-Marković, Jelena and Petrović, Slobodan",
year = "2012",
abstract = "The number of cases of fatal infections in humans and animals caused by multiresistant and panresistant bacterial strains has been dramatically increased over the past 10 years on almost every continent. Therefore, implementation of newer technologies in order to develop processes for isolation of substances with strong antibacterial activities from natural sources is of increasing interest. In this study, advantage of high pressure processing and supercritical fluid extraction with carbon dioxide in isolation of active principles from lichen Usnea barbata L was presented. Supercritical extraction showed extremely higher selectivity toward usnic acid compared to the conventional techniques tested. In order to simulate the process and estimate mass transfer coefficients, the new mathematical model of Sovova (2011) was applied. Supercritical extract obtained at 40 C and 30 MPa showed stronger antibacterial activity against the most of tested strains compared to pure usnic acid and extracts obtained using ethanol as a solvent. Further, supercritical extract with lower usnic acid content expressed stronger antibacterial activity against the majority of tested strains including MRSA strains compared to the pure usnic acid and the supercritical extract with the higher usnic acid content. The same extract was far more effective than ampicillin against Streptococcus uberis, all tested Enterococcus faecalis, MRSA and MRSA ATCC 33591. Against few tested strains, the supercritical extract was superior to erythromycin and penicillin as well. These findings justified possible benefits of inclusion of supercritical extracts into pharmaceutical and cosmetic formulations. Applied mathematical model described the SFE process with high accuracy.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "SFE as a superior technique for isolation of extracts with strong antibacterial activities from lichen Usnea barbata L.",
pages = "14-7",
volume = "72",
doi = "10.1016/j.supflu.2012.07.018"
}

Žižović, I., Ivanović, J., Mišić, D., Stamenić, M., Đorđević, S., Kukić-Marković, J.,& Petrović, S.. (2012). SFE as a superior technique for isolation of extracts with strong antibacterial activities from lichen Usnea barbata L.. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 72, 7-14.
https://doi.org/10.1016/j.supflu.2012.07.018

Žižović I, Ivanović J, Mišić D, Stamenić M, Đorđević S, Kukić-Marković J, Petrović S. SFE as a superior technique for isolation of extracts with strong antibacterial activities from lichen Usnea barbata L.. in Journal of Supercritical Fluids. 2012;72:7-14.
doi:10.1016/j.supflu.2012.07.018 .

Žižović, Irena, Ivanović, Jasna, Mišić, Dušan, Stamenić, Marko, Đorđević, Sofija, Kukić-Marković, Jelena, Petrović, Slobodan, "SFE as a superior technique for isolation of extracts with strong antibacterial activities from lichen Usnea barbata L." in Journal of Supercritical Fluids, 72 (2012):7-14,
https://doi.org/10.1016/j.supflu.2012.07.018 . .