TY  - CONF
AU  - Savić Gajić, Ivana M.
AU  - Savić, Ivan M.
AU  - Ivanovska, Aleksandra
AU  - Kostić, Mirjana
AU  - Svirčev, Zorica
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6823
AB  - The first stage in alginate production is the depigmentation and defatting of brown seaweed biomass using 70% (v/v) ethanol. The obtained ethanolic fraction is discarded from the further production process as a side product. Having in mind these facts, this study aimed to valorize the ethanolic extract generated during the alginate extraction from brown seaweed (Laminaria digitata). The possibility of valorization of the extract was estimated based on the determination of the total phenolic and flavonoid content, and the antioxidant activity. For the extract, the total phenolic and flavonoid content was 29.3 g gallic acid equivalent per 100 g dry weight and 1.49 g
rutin equivalent per 100 g dry weight, respectively. The results of the DPPH assay showed that the extract exhibited antioxidant activity with the IC50 value of 42.9 μg/mL. The antioxidant activity of the extract was almost the same as for synthetic antioxidant butylated hydroxytoluene (IC50 = 36.6 μg/mL). The obtained results indicated that the brown seaweed extract represents the source of phenolic compounds that have an expressed antioxidant activity. This approach is important because it utilizes the extract as the secondary raw material for the recovery of valuable compounds that can be significant as a starting raw material in various branches of industry.
PB  - Leskovac : Faculty of Technology
C3  - Book of abstracts / 15th International Symposium "Novel Technologies and Sustainable Development" Leskovac, October, 20-21, 2023
T1  - ESTIMATION OF THE POSSIBILITY FOR FURTHER APPLICATION OF ETHANOLIC FRACTION OBTAINED DURING ALGINATE PRODUCTION FROM BROWN SEAWEED BIOMASS
SP  - 81
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6823
ER  - 

@conference{
author = "Savić Gajić, Ivana M. and Savić, Ivan M. and Ivanovska, Aleksandra and Kostić, Mirjana and Svirčev, Zorica",
year = "2023",
abstract = "The first stage in alginate production is the depigmentation and defatting of brown seaweed biomass using 70% (v/v) ethanol. The obtained ethanolic fraction is discarded from the further production process as a side product. Having in mind these facts, this study aimed to valorize the ethanolic extract generated during the alginate extraction from brown seaweed (Laminaria digitata). The possibility of valorization of the extract was estimated based on the determination of the total phenolic and flavonoid content, and the antioxidant activity. For the extract, the total phenolic and flavonoid content was 29.3 g gallic acid equivalent per 100 g dry weight and 1.49 g
rutin equivalent per 100 g dry weight, respectively. The results of the DPPH assay showed that the extract exhibited antioxidant activity with the IC50 value of 42.9 μg/mL. The antioxidant activity of the extract was almost the same as for synthetic antioxidant butylated hydroxytoluene (IC50 = 36.6 μg/mL). The obtained results indicated that the brown seaweed extract represents the source of phenolic compounds that have an expressed antioxidant activity. This approach is important because it utilizes the extract as the secondary raw material for the recovery of valuable compounds that can be significant as a starting raw material in various branches of industry.",
publisher = "Leskovac : Faculty of Technology",
journal = "Book of abstracts / 15th International Symposium "Novel Technologies and Sustainable Development" Leskovac, October, 20-21, 2023",
title = "ESTIMATION OF THE POSSIBILITY FOR FURTHER APPLICATION OF ETHANOLIC FRACTION OBTAINED DURING ALGINATE PRODUCTION FROM BROWN SEAWEED BIOMASS",
pages = "81",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6823"
}

Savić Gajić, I. M., Savić, I. M., Ivanovska, A., Kostić, M.,& Svirčev, Z.. (2023). ESTIMATION OF THE POSSIBILITY FOR FURTHER APPLICATION OF ETHANOLIC FRACTION OBTAINED DURING ALGINATE PRODUCTION FROM BROWN SEAWEED BIOMASS. in Book of abstracts / 15th International Symposium "Novel Technologies and Sustainable Development" Leskovac, October, 20-21, 2023
Leskovac : Faculty of Technology., 81.
https://hdl.handle.net/21.15107/rcub_technorep_6823

Savić Gajić IM, Savić IM, Ivanovska A, Kostić M, Svirčev Z. ESTIMATION OF THE POSSIBILITY FOR FURTHER APPLICATION OF ETHANOLIC FRACTION OBTAINED DURING ALGINATE PRODUCTION FROM BROWN SEAWEED BIOMASS. in Book of abstracts / 15th International Symposium "Novel Technologies and Sustainable Development" Leskovac, October, 20-21, 2023. 2023;:81.
https://hdl.handle.net/21.15107/rcub_technorep_6823 .

Savić Gajić, Ivana M., Savić, Ivan M., Ivanovska, Aleksandra, Kostić, Mirjana, Svirčev, Zorica, "ESTIMATION OF THE POSSIBILITY FOR FURTHER APPLICATION OF ETHANOLIC FRACTION OBTAINED DURING ALGINATE PRODUCTION FROM BROWN SEAWEED BIOMASS" in Book of abstracts / 15th International Symposium "Novel Technologies and Sustainable Development" Leskovac, October, 20-21, 2023 (2023):81,
https://hdl.handle.net/21.15107/rcub_technorep_6823 .

TY  - JOUR
AU  - Vukašinović, Mila
AU  - Pantelić, Ivana
AU  - Savić, Sanela
AU  - Cekić, Nebojša
AU  - Vukašinović Sekulić, Maja
AU  - Antić Stanković, Jelena
AU  - Božić, Dragana D.
AU  - Tošić, Anđela
AU  - Tamburić, Slobodanka
AU  - Savić, Snežana D.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7071
AB  - Bioactive peptides are promising cosmetic active ingredients that can improve skin healthand appearance. They exhibit a broad spectrum of activity, including anti-aging, antioxidant, an-timicrobial, and anti-inflammatory effects. The aim of this study was to develop a safe, stable, andefficacious environmentally friendly (“green”) emulsion using a milk protein hydrolysate as a modelactive ingredient. Potential emulsions were formulated with biodegradable emollients, stabilizedwith naturally derived mixed emulsifier, and prepared by cold process. They were evaluated forrheological behavior (continuous rotation and oscillation tests), physical stability (dynamic me-chanical thermal analysis—DMTA test), and texture profiles, as well as cytotoxic, antioxidant, andantimicrobial effects. Rheological characterization revealed shear-thinning flow behavior with yieldpoint from continuous rotation tests and predominantly elastic character from oscillation (amplitudeand frequency sweep) tests, with small structural change detected in the DMTA test. These resultsimplied satisfactory rheological properties and good stability. Texture analysis revealed acceptablespreadability and substantivity of the emulsions. The protein hydrolysate showed antioxidant activity.The developed emulsions showed low antibacterial activity against selected microorganisms, butthis was due to the action of preservatives, not peptides. All potential emulsions showed a desirablesafety profile. The results obtained provide the basis for the next stage of formulation development,i.e., in vivo efficacy tests.
PB  - MDPI
T2  - Cosmetics
T1  - Development of a “Green” Emulsion with a Milk Protein Hydrolysate: An Evaluation of Rheology, Texture, In Vitro Bioactivity, and Safety
IS  - 6
SP  - 162
VL  - 10
DO  - 10.3390/cosmetics10060162
ER  - 

@article{
author = "Vukašinović, Mila and Pantelić, Ivana and Savić, Sanela and Cekić, Nebojša and Vukašinović Sekulić, Maja and Antić Stanković, Jelena and Božić, Dragana D. and Tošić, Anđela and Tamburić, Slobodanka and Savić, Snežana D.",
year = "2023",
abstract = "Bioactive peptides are promising cosmetic active ingredients that can improve skin healthand appearance. They exhibit a broad spectrum of activity, including anti-aging, antioxidant, an-timicrobial, and anti-inflammatory effects. The aim of this study was to develop a safe, stable, andefficacious environmentally friendly (“green”) emulsion using a milk protein hydrolysate as a modelactive ingredient. Potential emulsions were formulated with biodegradable emollients, stabilizedwith naturally derived mixed emulsifier, and prepared by cold process. They were evaluated forrheological behavior (continuous rotation and oscillation tests), physical stability (dynamic me-chanical thermal analysis—DMTA test), and texture profiles, as well as cytotoxic, antioxidant, andantimicrobial effects. Rheological characterization revealed shear-thinning flow behavior with yieldpoint from continuous rotation tests and predominantly elastic character from oscillation (amplitudeand frequency sweep) tests, with small structural change detected in the DMTA test. These resultsimplied satisfactory rheological properties and good stability. Texture analysis revealed acceptablespreadability and substantivity of the emulsions. The protein hydrolysate showed antioxidant activity.The developed emulsions showed low antibacterial activity against selected microorganisms, butthis was due to the action of preservatives, not peptides. All potential emulsions showed a desirablesafety profile. The results obtained provide the basis for the next stage of formulation development,i.e., in vivo efficacy tests.",
publisher = "MDPI",
journal = "Cosmetics",
title = "Development of a “Green” Emulsion with a Milk Protein Hydrolysate: An Evaluation of Rheology, Texture, In Vitro Bioactivity, and Safety",
number = "6",
pages = "162",
volume = "10",
doi = "10.3390/cosmetics10060162"
}

Vukašinović, M., Pantelić, I., Savić, S., Cekić, N., Vukašinović Sekulić, M., Antić Stanković, J., Božić, D. D., Tošić, A., Tamburić, S.,& Savić, S. D.. (2023). Development of a “Green” Emulsion with a Milk Protein Hydrolysate: An Evaluation of Rheology, Texture, In Vitro Bioactivity, and Safety. in Cosmetics
MDPI., 10(6), 162.
https://doi.org/10.3390/cosmetics10060162

Vukašinović M, Pantelić I, Savić S, Cekić N, Vukašinović Sekulić M, Antić Stanković J, Božić DD, Tošić A, Tamburić S, Savić SD. Development of a “Green” Emulsion with a Milk Protein Hydrolysate: An Evaluation of Rheology, Texture, In Vitro Bioactivity, and Safety. in Cosmetics. 2023;10(6):162.
doi:10.3390/cosmetics10060162 .

Vukašinović, Mila, Pantelić, Ivana, Savić, Sanela, Cekić, Nebojša, Vukašinović Sekulić, Maja, Antić Stanković, Jelena, Božić, Dragana D., Tošić, Anđela, Tamburić, Slobodanka, Savić, Snežana D., "Development of a “Green” Emulsion with a Milk Protein Hydrolysate: An Evaluation of Rheology, Texture, In Vitro Bioactivity, and Safety" in Cosmetics, 10, no. 6 (2023):162,
https://doi.org/10.3390/cosmetics10060162 . .

TY  - JOUR
AU  - Ilić-Stojanović, Snežana
AU  - Nikolić, Ljubiša
AU  - Nikolić, Vesna
AU  - Ristić, Ivan
AU  - Cakić, Suzana
AU  - Petrović, Slobodan D.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5805
AB  - The objectives of this study are the synthesis of thermosensitive poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate), p(NiPAm-HPMet), hydrogels and the analysis of a drug-delivery system based on piroxicam, as a model drug, and synthesized hydrogels. A high pressure liquid chromatography method has been used in order to determine both qualitative and quantitative amounts of unreacted monomers and crosslinkers from polymerized hydrogels. Swelling kinetics and the order of a swelling process of the hydrogels have been analyzed at 10 and 40 °C. The copolymers’ thermal properties have been monitored by the differential scanning calorimetry (DSC) method. DSC termograms have shown that melting occurs in two temperature intervals (142.36–150.72 °C and 153.14–156.49 °C). A matrix system with incorporated piroxicam has been analyzed by using FTIR and SEM methods. Structural analysis has demonstrated that intermolecular non-covalent interactions have been built between side-groups of copolymer and loaded piroxicam. Morphology of p(NiPAm-HPMet) after drug incorporation indicates the piroxicam presence into the copolymer pores. Kinetic parameters of the piroxicam release from hydrogels at 37 °C and pH 7.4 indicate that the fluid transport mechanism corresponds to Fickian diffusion. As a result, formulation of thermosensitive p(NiPAm-HPMet) hydrogels with incorporated piroxicam could be of interest for further testing as a drug carrier for modulated and prolonged release, especially for topical administration.
PB  - MDPI
T2  - Gels
T1  - Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery
IS  - 1
SP  - 70
VL  - 9
DO  - 10.3390/gels9010070
ER  - 

@article{
author = "Ilić-Stojanović, Snežana and Nikolić, Ljubiša and Nikolić, Vesna and Ristić, Ivan and Cakić, Suzana and Petrović, Slobodan D.",
year = "2023",
abstract = "The objectives of this study are the synthesis of thermosensitive poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate), p(NiPAm-HPMet), hydrogels and the analysis of a drug-delivery system based on piroxicam, as a model drug, and synthesized hydrogels. A high pressure liquid chromatography method has been used in order to determine both qualitative and quantitative amounts of unreacted monomers and crosslinkers from polymerized hydrogels. Swelling kinetics and the order of a swelling process of the hydrogels have been analyzed at 10 and 40 °C. The copolymers’ thermal properties have been monitored by the differential scanning calorimetry (DSC) method. DSC termograms have shown that melting occurs in two temperature intervals (142.36–150.72 °C and 153.14–156.49 °C). A matrix system with incorporated piroxicam has been analyzed by using FTIR and SEM methods. Structural analysis has demonstrated that intermolecular non-covalent interactions have been built between side-groups of copolymer and loaded piroxicam. Morphology of p(NiPAm-HPMet) after drug incorporation indicates the piroxicam presence into the copolymer pores. Kinetic parameters of the piroxicam release from hydrogels at 37 °C and pH 7.4 indicate that the fluid transport mechanism corresponds to Fickian diffusion. As a result, formulation of thermosensitive p(NiPAm-HPMet) hydrogels with incorporated piroxicam could be of interest for further testing as a drug carrier for modulated and prolonged release, especially for topical administration.",
publisher = "MDPI",
journal = "Gels",
title = "Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery",
number = "1",
pages = "70",
volume = "9",
doi = "10.3390/gels9010070"
}

Ilić-Stojanović, S., Nikolić, L., Nikolić, V., Ristić, I., Cakić, S.,& Petrović, S. D.. (2023). Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery. in Gels
MDPI., 9(1), 70.
https://doi.org/10.3390/gels9010070

Ilić-Stojanović S, Nikolić L, Nikolić V, Ristić I, Cakić S, Petrović SD. Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery. in Gels. 2023;9(1):70.
doi:10.3390/gels9010070 .

Ilić-Stojanović, Snežana, Nikolić, Ljubiša, Nikolić, Vesna, Ristić, Ivan, Cakić, Suzana, Petrović, Slobodan D., "Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery" in Gels, 9, no. 1 (2023):70,
https://doi.org/10.3390/gels9010070 . .

TY  - JOUR
AU  - Ilić-Stojanović, Snežana
AU  - Nikolić, Ljubiša
AU  - Nikolić, Vesna
AU  - Ristić, Ivan
AU  - Cakić, Suzana
AU  - Petrović, Slobodan D.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6664
AB  - The purposes of this study are the polymerization of temperature-sensitive copolymers based on N-isopropyl acrylamide and 10 mol % of 2-hydroxypropylmethacrylate, characterisations of their thermal, morphological and swelling properties, as well as the analysis of potential application in drug-delivery systems. Acetaminophen, the representative of non-steroidal anti-inflammatory drugs, was used as a model drug in this study. It is a common pain relief drug, which is also used for fever treatment. However, oral administration comes with certain health risks, mainly the overdose and frequent administration of up to four times a day. The goal of applying temperature-sensitive hydrogel is to enable extended administration once a day, depending on the body temperature. The swelling behavior of the obtained poly(N-isopropyl acrylamide-co-2-hydroxypropylmethacrylate) (p(NIPA/HPMA)) hydrogels and their temperature-sensitivity, kinetics and order of swelling processes at 18 and 38 °C were analyzed. The thermal properties of these hydrogels were observed by the DSC method, and the obtained thermograms showed both melting and glass transitions. The drug delivery system of p(NIPA/HPMA) hydrogels with loaded acetaminophen was analyzed using scanning electron microscopy and Fourier transform infrared spectroscopy methods. Structural analysis of FTIR spectra indicates that non-covalent intermolecular interactions of the type of hydrogen bonds were formed among functional groups of acetaminophen and side-chains of p(NIPA/HPMA) hydrogels. The surface structure of p(NIPA/HPMA) hydrogels after drug loading indicates the acetaminophen presence into the pores of the hydrogel network, and their loading efficiency was higher than 92%. Qualitative and quantitative analysis of acetaminophen, determined by the high-pressure liquid chromatography method, showed that about 90–99% of the loaded amount was released from p(NIPA/HPMA) hydrogels within 24 h. Kinetic parameters of the acetaminophen release under simulated gastrointestinal conditions were determined. Based on obtained results, the drug delivery system of temperature-sensitive p(NIPA/HPMA) hydrogels with loaded acetaminophen could be suitable for additional investigation for modulated drug administration, e.g., for extended drug administration.
PB  - MDPI
T2  - Gels
T1  - Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen
IS  - 9
SP  - 684
VL  - 9
DO  - 10.3390/gels9090684
ER  - 

@article{
author = "Ilić-Stojanović, Snežana and Nikolić, Ljubiša and Nikolić, Vesna and Ristić, Ivan and Cakić, Suzana and Petrović, Slobodan D.",
year = "2023",
abstract = "The purposes of this study are the polymerization of temperature-sensitive copolymers based on N-isopropyl acrylamide and 10 mol % of 2-hydroxypropylmethacrylate, characterisations of their thermal, morphological and swelling properties, as well as the analysis of potential application in drug-delivery systems. Acetaminophen, the representative of non-steroidal anti-inflammatory drugs, was used as a model drug in this study. It is a common pain relief drug, which is also used for fever treatment. However, oral administration comes with certain health risks, mainly the overdose and frequent administration of up to four times a day. The goal of applying temperature-sensitive hydrogel is to enable extended administration once a day, depending on the body temperature. The swelling behavior of the obtained poly(N-isopropyl acrylamide-co-2-hydroxypropylmethacrylate) (p(NIPA/HPMA)) hydrogels and their temperature-sensitivity, kinetics and order of swelling processes at 18 and 38 °C were analyzed. The thermal properties of these hydrogels were observed by the DSC method, and the obtained thermograms showed both melting and glass transitions. The drug delivery system of p(NIPA/HPMA) hydrogels with loaded acetaminophen was analyzed using scanning electron microscopy and Fourier transform infrared spectroscopy methods. Structural analysis of FTIR spectra indicates that non-covalent intermolecular interactions of the type of hydrogen bonds were formed among functional groups of acetaminophen and side-chains of p(NIPA/HPMA) hydrogels. The surface structure of p(NIPA/HPMA) hydrogels after drug loading indicates the acetaminophen presence into the pores of the hydrogel network, and their loading efficiency was higher than 92%. Qualitative and quantitative analysis of acetaminophen, determined by the high-pressure liquid chromatography method, showed that about 90–99% of the loaded amount was released from p(NIPA/HPMA) hydrogels within 24 h. Kinetic parameters of the acetaminophen release under simulated gastrointestinal conditions were determined. Based on obtained results, the drug delivery system of temperature-sensitive p(NIPA/HPMA) hydrogels with loaded acetaminophen could be suitable for additional investigation for modulated drug administration, e.g., for extended drug administration.",
publisher = "MDPI",
journal = "Gels",
title = "Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen",
number = "9",
pages = "684",
volume = "9",
doi = "10.3390/gels9090684"
}

Ilić-Stojanović, S., Nikolić, L., Nikolić, V., Ristić, I., Cakić, S.,& Petrović, S. D.. (2023). Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen. in Gels
MDPI., 9(9), 684.
https://doi.org/10.3390/gels9090684

Ilić-Stojanović S, Nikolić L, Nikolić V, Ristić I, Cakić S, Petrović SD. Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen. in Gels. 2023;9(9):684.
doi:10.3390/gels9090684 .

Ilić-Stojanović, Snežana, Nikolić, Ljubiša, Nikolić, Vesna, Ristić, Ivan, Cakić, Suzana, Petrović, Slobodan D., "Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen" in Gels, 9, no. 9 (2023):684,
https://doi.org/10.3390/gels9090684 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Stanković, Milica
AU  - Roganović, Sonja
AU  - Nešić, Ivana
AU  - Zvezdanović, Jelena
AU  - Tadić, Vanja
AU  - Žižović, Irena
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5230
AB  - Ethnopharmacological relevance: Helichrysum italicum has been widely used in traditional medicine to treat allergies, colds, cough, skin, liver and gallbladder disorders, inflammation, infections, and sleeplessness. Furthermore, it possesses considerable wound healing and skin protective properties, documented by several in vivo studies performed on animals. However, there is a lack of experimental evidence supporting its potential as a topical agent tested by human clinical trials. Aim of the study: The study aimed to investigate the skin protective activity of cotton gauze and polypropylene non-woven fabric, impregnated with H. italicum extract by the integrated supercritical CO2 extraction-supercritical solvent impregnation process. Materials and methods: The integrated process of supercritical CO2 extraction of H. italicum and the impregnation of cotton gauze and polypropylene non-woven fabric was performed under 350 bar and 40 °C with and without the addition of ethanol as a cosolvent. Impregnated textile materials were tested in vivo for their bioactivity on irritated human skin. Randomized in vivo studies performed involved assays of both safety and efficacy of the impregnated textiles. The effects were evaluated using the in vivo non-invasive biophysical measurements of the following skin parameters: electrical capacitance, transepidermal water loss, melanin index, erythema index, and skin pH. Results: Both cotton gauze and polypropylene non-woven fabric were impregnated with H. italicum extracts under supercritical conditions with considerable values of the impregnation yield (1.97%–4.25%). The addition of ethanol as a cosolvent during the process caused significant changes in the incorporated extracts’ impregnation yield and chemical profile. Both impregnated textile materials were safe, evaluated by their testing on the human skin with no cause of any irritation and redness. However, efficacy studies revealed that polypropylene non-woven fabric impregnated with H. italicum extract with ethanol as a cosolvent, possessed significantly greater potential for skin protection than the other investigated samples. Conclusions: The present study demonstrated the feasibility of the combined supercritical extraction and impregnation process in developing materials for topical application based on H. italicum extract. The results of in vivo studies performed on human volunteers confirmed the suitability of H. italicum active components to be a part of human skin protective preparations because of their ability to maintain the skin unimpaired. Traditionally claimed applications as a medicinal plant capable of regenerating skin have been scientifically proven, in addition to employing green technology in obtaining the impregnated materials with a broad spectrum of utilization.
PB  - Elsevier Ireland Ltd
T2  - Journal of Ethnopharmacology
T1  - Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin
SP  - 115779
VL  - 301
DO  - 10.1016/j.jep.2022.115779
ER  - 

@article{
author = "Maksimović, Svetolik and Stanković, Milica and Roganović, Sonja and Nešić, Ivana and Zvezdanović, Jelena and Tadić, Vanja and Žižović, Irena",
year = "2023",
abstract = "Ethnopharmacological relevance: Helichrysum italicum has been widely used in traditional medicine to treat allergies, colds, cough, skin, liver and gallbladder disorders, inflammation, infections, and sleeplessness. Furthermore, it possesses considerable wound healing and skin protective properties, documented by several in vivo studies performed on animals. However, there is a lack of experimental evidence supporting its potential as a topical agent tested by human clinical trials. Aim of the study: The study aimed to investigate the skin protective activity of cotton gauze and polypropylene non-woven fabric, impregnated with H. italicum extract by the integrated supercritical CO2 extraction-supercritical solvent impregnation process. Materials and methods: The integrated process of supercritical CO2 extraction of H. italicum and the impregnation of cotton gauze and polypropylene non-woven fabric was performed under 350 bar and 40 °C with and without the addition of ethanol as a cosolvent. Impregnated textile materials were tested in vivo for their bioactivity on irritated human skin. Randomized in vivo studies performed involved assays of both safety and efficacy of the impregnated textiles. The effects were evaluated using the in vivo non-invasive biophysical measurements of the following skin parameters: electrical capacitance, transepidermal water loss, melanin index, erythema index, and skin pH. Results: Both cotton gauze and polypropylene non-woven fabric were impregnated with H. italicum extracts under supercritical conditions with considerable values of the impregnation yield (1.97%–4.25%). The addition of ethanol as a cosolvent during the process caused significant changes in the incorporated extracts’ impregnation yield and chemical profile. Both impregnated textile materials were safe, evaluated by their testing on the human skin with no cause of any irritation and redness. However, efficacy studies revealed that polypropylene non-woven fabric impregnated with H. italicum extract with ethanol as a cosolvent, possessed significantly greater potential for skin protection than the other investigated samples. Conclusions: The present study demonstrated the feasibility of the combined supercritical extraction and impregnation process in developing materials for topical application based on H. italicum extract. The results of in vivo studies performed on human volunteers confirmed the suitability of H. italicum active components to be a part of human skin protective preparations because of their ability to maintain the skin unimpaired. Traditionally claimed applications as a medicinal plant capable of regenerating skin have been scientifically proven, in addition to employing green technology in obtaining the impregnated materials with a broad spectrum of utilization.",
publisher = "Elsevier Ireland Ltd",
journal = "Journal of Ethnopharmacology",
title = "Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin",
pages = "115779",
volume = "301",
doi = "10.1016/j.jep.2022.115779"
}

Maksimović, S., Stanković, M., Roganović, S., Nešić, I., Zvezdanović, J., Tadić, V.,& Žižović, I.. (2023). Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin. in Journal of Ethnopharmacology
Elsevier Ireland Ltd., 301, 115779.
https://doi.org/10.1016/j.jep.2022.115779

Maksimović S, Stanković M, Roganović S, Nešić I, Zvezdanović J, Tadić V, Žižović I. Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin. in Journal of Ethnopharmacology. 2023;301:115779.
doi:10.1016/j.jep.2022.115779 .

Maksimović, Svetolik, Stanković, Milica, Roganović, Sonja, Nešić, Ivana, Zvezdanović, Jelena, Tadić, Vanja, Žižović, Irena, "Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin" in Journal of Ethnopharmacology, 301 (2023):115779,
https://doi.org/10.1016/j.jep.2022.115779 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Gajić Savić, Ivana
AU  - Lađarević, Jelena
AU  - Milošević, Marija
AU  - Savić, Ivan
AU  - Mihajlovski, Katarina
AU  - Kostić, Mirjana
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5237
AB  - A diluted ethanol orange peel extract was used for sustainable dyeing and functionalization of different fabrics. The extract analysis was performed using UPLC-ESI-MS/MS; its total flavonoid (0.67 g RE/100 g d.w.) and antioxidant (2.81 g GAE/100 g d.w.) contents and antioxidant activity (IC50 of 65.5 µg/mL) were also determined. The extract dyeing performance at various dyebath pH values was evaluated using multifiber fabric. Among six fabrics, extract possessed the ability for dyeing wool, polyamide, and cellulose acetate (at pH 4.5), which color strength (K/S) values increased after washing (9.7–19.8 vs. 11.6–23.2). Extract:water ratio of 20:35 (v/v) was found to be sufficient for achieving satisfactory K/S values (i.e., 20.17, 12.56, and 10.38 for wool, polyamide, and cellulose acetate, respectively) that were slightly changed after washing. The optimal dyeing temperatures for wool, polyamide, and cellulose acetate are 55, 35, and 25 °C, while the equilibrium dye exhaustion at those temperatures was achieved after 45, 120, and 90 min, respectively. The color coordinate measurements revealed that wool and polyamide fabrics are yellower than cellulose acetate, while, compared to polyamide and cellulose acetate, wool is redder. Possible interactions between selected fabrics and extract compounds are suggested. All fabrics possessed excellent antioxidant activity (88.6–99.6%) both before and after washing. Cellulose acetate provided maximum bacterial reduction (99.99%) for Escherichia coli, and Staphylococcus aureus, which in the case of Staphylococcus aureus remained unchanged after washing. Orange peel extract could be used for simultaneous dyeing and functionalization of wool and polyamide (excellent antioxidant activity) and cellulose acetate (excellent antioxidant and antibacterial activity) fabrics.
PB  - MDPI
T2  - Antioxidants
T1  - Sustainable Dyeing and Functionalization of Different Fibers Using Orange Peel Extract’s Antioxidants
IS  - 10
SP  - 2059
VL  - 11
DO  - 10.3390/antiox11102059
ER  - 

@article{
author = "Ivanovska, Aleksandra and Gajić Savić, Ivana and Lađarević, Jelena and Milošević, Marija and Savić, Ivan and Mihajlovski, Katarina and Kostić, Mirjana",
year = "2022",
abstract = "A diluted ethanol orange peel extract was used for sustainable dyeing and functionalization of different fabrics. The extract analysis was performed using UPLC-ESI-MS/MS; its total flavonoid (0.67 g RE/100 g d.w.) and antioxidant (2.81 g GAE/100 g d.w.) contents and antioxidant activity (IC50 of 65.5 µg/mL) were also determined. The extract dyeing performance at various dyebath pH values was evaluated using multifiber fabric. Among six fabrics, extract possessed the ability for dyeing wool, polyamide, and cellulose acetate (at pH 4.5), which color strength (K/S) values increased after washing (9.7–19.8 vs. 11.6–23.2). Extract:water ratio of 20:35 (v/v) was found to be sufficient for achieving satisfactory K/S values (i.e., 20.17, 12.56, and 10.38 for wool, polyamide, and cellulose acetate, respectively) that were slightly changed after washing. The optimal dyeing temperatures for wool, polyamide, and cellulose acetate are 55, 35, and 25 °C, while the equilibrium dye exhaustion at those temperatures was achieved after 45, 120, and 90 min, respectively. The color coordinate measurements revealed that wool and polyamide fabrics are yellower than cellulose acetate, while, compared to polyamide and cellulose acetate, wool is redder. Possible interactions between selected fabrics and extract compounds are suggested. All fabrics possessed excellent antioxidant activity (88.6–99.6%) both before and after washing. Cellulose acetate provided maximum bacterial reduction (99.99%) for Escherichia coli, and Staphylococcus aureus, which in the case of Staphylococcus aureus remained unchanged after washing. Orange peel extract could be used for simultaneous dyeing and functionalization of wool and polyamide (excellent antioxidant activity) and cellulose acetate (excellent antioxidant and antibacterial activity) fabrics.",
publisher = "MDPI",
journal = "Antioxidants",
title = "Sustainable Dyeing and Functionalization of Different Fibers Using Orange Peel Extract’s Antioxidants",
number = "10",
pages = "2059",
volume = "11",
doi = "10.3390/antiox11102059"
}

Ivanovska, A., Gajić Savić, I., Lađarević, J., Milošević, M., Savić, I., Mihajlovski, K.,& Kostić, M.. (2022). Sustainable Dyeing and Functionalization of Different Fibers Using Orange Peel Extract’s Antioxidants. in Antioxidants
MDPI., 11(10), 2059.
https://doi.org/10.3390/antiox11102059

Ivanovska A, Gajić Savić I, Lađarević J, Milošević M, Savić I, Mihajlovski K, Kostić M. Sustainable Dyeing and Functionalization of Different Fibers Using Orange Peel Extract’s Antioxidants. in Antioxidants. 2022;11(10):2059.
doi:10.3390/antiox11102059 .

Ivanovska, Aleksandra, Gajić Savić, Ivana, Lađarević, Jelena, Milošević, Marija, Savić, Ivan, Mihajlovski, Katarina, Kostić, Mirjana, "Sustainable Dyeing and Functionalization of Different Fibers Using Orange Peel Extract’s Antioxidants" in Antioxidants, 11, no. 10 (2022):2059,
https://doi.org/10.3390/antiox11102059 . .

TY  - JOUR
AU  - Miladinovic, Marija R.
AU  - Krstic, Jugoslav B.
AU  - Zdujic, Miodrag, V
AU  - Veselinovic, Ljiljana M.
AU  - Veljović, Đorđe
AU  - Bankovic-Ilic, Ivana B.
AU  - Stamenkovic, Olivera S.
AU  - Veljkovic, Vlada B.
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4976
AB  - Hazelnut shell ash was investigated as a new base catalyst for the transesterification of used cooking sunflower oil to biodiesel. To understand its catalytic properties, the prepared ash was characterized by EDX, XRD, TGA/DTA, Hg porosimetry, N-2 physisorption, FE-SEM, and basic strength measurements. The effects of the catalyst loading in the range of 1-5% of the oil weight and the methanol-to-oil molar ratio of 6:1-18:1 on the kinetics of the fatty acid methyl esters synthesis were established. Moreover, the leaching and reusability of the catalyst were assessed. The obtained results revealed that hazelnut shell ash was mostly composed of K, Ca, and Mg. The highest ester content (98%) was achieved at the catalyst loading of 5%, the methanol-to-oil molar ratio of 12:1, and the reaction time of 10 min. The contribution of homogeneous catalysis because of the catalyst leaching was confirmed but did not determine the overall reaction rate. The catalyst can be reused after the recalcination at 800 degrees C for 2 h achieving the high methyl esters content (>96%) in 30 min after three subsequent runs. The overall reaction followed the pseudo-first-order kinetics with respect to triacylglycerols. A linear relationship between the apparent reaction rate constant and the catalyst loading and the methanol-to-oil molar ratio was determined. The determined value of the reaction rate constant was 0.0576 dm(6)/(min.mol(2)).
T2  - Renewable Energy
T1  - Transesterification of used cooking sunflower oil catalyzed by hazelnut shell ash
EP  - 113
SP  - 103
VL  - 183
DO  - 10.1016/j.renene.2021.10.071
ER  - 

@article{
author = "Miladinovic, Marija R. and Krstic, Jugoslav B. and Zdujic, Miodrag, V and Veselinovic, Ljiljana M. and Veljović, Đorđe and Bankovic-Ilic, Ivana B. and Stamenkovic, Olivera S. and Veljkovic, Vlada B.",
year = "2022",
abstract = "Hazelnut shell ash was investigated as a new base catalyst for the transesterification of used cooking sunflower oil to biodiesel. To understand its catalytic properties, the prepared ash was characterized by EDX, XRD, TGA/DTA, Hg porosimetry, N-2 physisorption, FE-SEM, and basic strength measurements. The effects of the catalyst loading in the range of 1-5% of the oil weight and the methanol-to-oil molar ratio of 6:1-18:1 on the kinetics of the fatty acid methyl esters synthesis were established. Moreover, the leaching and reusability of the catalyst were assessed. The obtained results revealed that hazelnut shell ash was mostly composed of K, Ca, and Mg. The highest ester content (98%) was achieved at the catalyst loading of 5%, the methanol-to-oil molar ratio of 12:1, and the reaction time of 10 min. The contribution of homogeneous catalysis because of the catalyst leaching was confirmed but did not determine the overall reaction rate. The catalyst can be reused after the recalcination at 800 degrees C for 2 h achieving the high methyl esters content (>96%) in 30 min after three subsequent runs. The overall reaction followed the pseudo-first-order kinetics with respect to triacylglycerols. A linear relationship between the apparent reaction rate constant and the catalyst loading and the methanol-to-oil molar ratio was determined. The determined value of the reaction rate constant was 0.0576 dm(6)/(min.mol(2)).",
journal = "Renewable Energy",
title = "Transesterification of used cooking sunflower oil catalyzed by hazelnut shell ash",
pages = "113-103",
volume = "183",
doi = "10.1016/j.renene.2021.10.071"
}

Miladinovic, M. R., Krstic, J. B., Zdujic, M. V., Veselinovic, L. M., Veljović, Đ., Bankovic-Ilic, I. B., Stamenkovic, O. S.,& Veljkovic, V. B.. (2022). Transesterification of used cooking sunflower oil catalyzed by hazelnut shell ash. in Renewable Energy, 183, 103-113.
https://doi.org/10.1016/j.renene.2021.10.071

Miladinovic MR, Krstic JB, Zdujic MV, Veselinovic LM, Veljović Đ, Bankovic-Ilic IB, Stamenkovic OS, Veljkovic VB. Transesterification of used cooking sunflower oil catalyzed by hazelnut shell ash. in Renewable Energy. 2022;183:103-113.
doi:10.1016/j.renene.2021.10.071 .

Miladinovic, Marija R., Krstic, Jugoslav B., Zdujic, Miodrag, V, Veselinovic, Ljiljana M., Veljović, Đorđe, Bankovic-Ilic, Ivana B., Stamenkovic, Olivera S., Veljkovic, Vlada B., "Transesterification of used cooking sunflower oil catalyzed by hazelnut shell ash" in Renewable Energy, 183 (2022):103-113,
https://doi.org/10.1016/j.renene.2021.10.071 . .

TY  - JOUR
AU  - Ilić-Stojanović, Snežana
AU  - Nikolić, Ljubiša
AU  - Nikolić, Vesna
AU  - Petrović, Slobodan
AU  - Oro, Violeta
AU  - Mitić, Žarko
AU  - Najman, Stevo
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4899
AB  - In this study, poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate) hydrogels were synthesized using free radical initiated copolymerization method. Four hydrogels with different cross-linker concentrations were prepared. Semi-crystalline, cross-linked copolymer networks were confirmed by FTIR, SEM and XRD analysis. Variation of swelling behaviour was monitored gravimetrically and thermo-responsiveness has been noticed. An application of synthesized thermo-responsive hydrogels as carriers for the modulated release of anti-inflammatory model drug was investigated. Moreover, naproxen loading into these hydrogels was also determined using FTIR, SEM and XRD techniques and release was analyzed using HPLC method at simulated physiological conditions. Swelling kinetic and mechanism of water transport, as well as diffusion of naproxen through the hydrogels were analyzed. Thus, the aim of this work was to study various compositions of obtained hydrogels and their possibility of application as a thermo-responsive carrier for prolonged naproxen release in order to evaluate as a potential candidate for drug carrier in future pharmaceutical applications.
T2  - Pharmaceutics
T1  - Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study
IS  - 2
VL  - 13
DO  - 10.3390/pharmaceutics13020158
ER  - 

@article{
author = "Ilić-Stojanović, Snežana and Nikolić, Ljubiša and Nikolić, Vesna and Petrović, Slobodan and Oro, Violeta and Mitić, Žarko and Najman, Stevo",
year = "2021",
abstract = "In this study, poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate) hydrogels were synthesized using free radical initiated copolymerization method. Four hydrogels with different cross-linker concentrations were prepared. Semi-crystalline, cross-linked copolymer networks were confirmed by FTIR, SEM and XRD analysis. Variation of swelling behaviour was monitored gravimetrically and thermo-responsiveness has been noticed. An application of synthesized thermo-responsive hydrogels as carriers for the modulated release of anti-inflammatory model drug was investigated. Moreover, naproxen loading into these hydrogels was also determined using FTIR, SEM and XRD techniques and release was analyzed using HPLC method at simulated physiological conditions. Swelling kinetic and mechanism of water transport, as well as diffusion of naproxen through the hydrogels were analyzed. Thus, the aim of this work was to study various compositions of obtained hydrogels and their possibility of application as a thermo-responsive carrier for prolonged naproxen release in order to evaluate as a potential candidate for drug carrier in future pharmaceutical applications.",
journal = "Pharmaceutics",
title = "Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study",
number = "2",
volume = "13",
doi = "10.3390/pharmaceutics13020158"
}

Ilić-Stojanović, S., Nikolić, L., Nikolić, V., Petrović, S., Oro, V., Mitić, Ž.,& Najman, S.. (2021). Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study. in Pharmaceutics, 13(2).
https://doi.org/10.3390/pharmaceutics13020158

Ilić-Stojanović S, Nikolić L, Nikolić V, Petrović S, Oro V, Mitić Ž, Najman S. Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study. in Pharmaceutics. 2021;13(2).
doi:10.3390/pharmaceutics13020158 .

Ilić-Stojanović, Snežana, Nikolić, Ljubiša, Nikolić, Vesna, Petrović, Slobodan, Oro, Violeta, Mitić, Žarko, Najman, Stevo, "Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study" in Pharmaceutics, 13, no. 2 (2021),
https://doi.org/10.3390/pharmaceutics13020158 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Tadic, Vanja
AU  - Zvezdanovic, Jelena
AU  - Zizovic, Irena
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4904
AB  - Helichrysum italicum (Roth) G. Don fil., Asteraceae, possesses numerous secondary plant metabolites with a wide range of biological activities. Yet, data on the potential of supercritical fluid extraction (SFE) in their isolation are scarce. This study provides analyses of the chemical profiles of extracts obtained by SFE with or without ethanol as a cosolvent using GC-FID, GC-MS, HPLC, and UHPLC-MS techniques. Among the compounds with proven biological activity identified, the presence of arzanol was confirmed. In the next step, the integrated process of supercritical fluid extraction and impregnation was applied to deliver active compounds to cotton gauze and polypropylene fabric for possible topical applications. The analytical procedures results showed a considerable affinity of both textile materials for incorporating active components present in the H. italicum. The study indicated the high-pressure techniques applied as very efficient in the isolation of bioactive components from H. italicum and their adsorption on selected carriers.
T2  - Journal of Supercritical Fluids
T1  - Utilization of supercritical CO2 in bioactive principles isolation from Helichrysum italicum and their adsorption on selected fabrics
VL  - 171
DO  - 10.1016/j.supflu.2021.105197
ER  - 

@article{
author = "Maksimović, Svetolik and Tadic, Vanja and Zvezdanovic, Jelena and Zizovic, Irena",
year = "2021",
abstract = "Helichrysum italicum (Roth) G. Don fil., Asteraceae, possesses numerous secondary plant metabolites with a wide range of biological activities. Yet, data on the potential of supercritical fluid extraction (SFE) in their isolation are scarce. This study provides analyses of the chemical profiles of extracts obtained by SFE with or without ethanol as a cosolvent using GC-FID, GC-MS, HPLC, and UHPLC-MS techniques. Among the compounds with proven biological activity identified, the presence of arzanol was confirmed. In the next step, the integrated process of supercritical fluid extraction and impregnation was applied to deliver active compounds to cotton gauze and polypropylene fabric for possible topical applications. The analytical procedures results showed a considerable affinity of both textile materials for incorporating active components present in the H. italicum. The study indicated the high-pressure techniques applied as very efficient in the isolation of bioactive components from H. italicum and their adsorption on selected carriers.",
journal = "Journal of Supercritical Fluids",
title = "Utilization of supercritical CO2 in bioactive principles isolation from Helichrysum italicum and their adsorption on selected fabrics",
volume = "171",
doi = "10.1016/j.supflu.2021.105197"
}

Maksimović, S., Tadic, V., Zvezdanovic, J.,& Zizovic, I.. (2021). Utilization of supercritical CO2 in bioactive principles isolation from Helichrysum italicum and their adsorption on selected fabrics. in Journal of Supercritical Fluids, 171.
https://doi.org/10.1016/j.supflu.2021.105197

Maksimović S, Tadic V, Zvezdanovic J, Zizovic I. Utilization of supercritical CO2 in bioactive principles isolation from Helichrysum italicum and their adsorption on selected fabrics. in Journal of Supercritical Fluids. 2021;171.
doi:10.1016/j.supflu.2021.105197 .

Maksimović, Svetolik, Tadic, Vanja, Zvezdanovic, Jelena, Zizovic, Irena, "Utilization of supercritical CO2 in bioactive principles isolation from Helichrysum italicum and their adsorption on selected fabrics" in Journal of Supercritical Fluids, 171 (2021),
https://doi.org/10.1016/j.supflu.2021.105197 . .

TY  - JOUR
AU  - Pavlović, Stefan
AU  - Marinković, Dalibor
AU  - Kostić, Milan
AU  - Lončarević, Davor
AU  - Mojović, Ljiljana
AU  - Stanković, Miroslav
AU  - Veljković, Vlada B.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4586
AB  - Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZMFA) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZMFA was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZMFA supported calcium oxide catalyst (xCaO/ZMFA) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5–20 wt%) over ZMFA and thermal treatment at different temperatures (450–600 °C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZMFA catalyst under reaction conditions: temperature of 60 °C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 °C. At calcination temperatures above 550 °C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.
PB  - Elsevier
T2  - Fuel
T1  - The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production
SP  - 119912
VL  - 289
DO  - 10.1016/j.fuel.2020.119912
ER  - 

@article{
author = "Pavlović, Stefan and Marinković, Dalibor and Kostić, Milan and Lončarević, Davor and Mojović, Ljiljana and Stanković, Miroslav and Veljković, Vlada B.",
year = "2021",
abstract = "Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZMFA) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZMFA was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZMFA supported calcium oxide catalyst (xCaO/ZMFA) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5–20 wt%) over ZMFA and thermal treatment at different temperatures (450–600 °C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZMFA catalyst under reaction conditions: temperature of 60 °C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 °C. At calcination temperatures above 550 °C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.",
publisher = "Elsevier",
journal = "Fuel",
title = "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production",
pages = "119912",
volume = "289",
doi = "10.1016/j.fuel.2020.119912"
}

Pavlović, S., Marinković, D., Kostić, M., Lončarević, D., Mojović, L., Stanković, M.,& Veljković, V. B.. (2021). The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel
Elsevier., 289, 119912.
https://doi.org/10.1016/j.fuel.2020.119912

Pavlović S, Marinković D, Kostić M, Lončarević D, Mojović L, Stanković M, Veljković VB. The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel. 2021;289:119912.
doi:10.1016/j.fuel.2020.119912 .

Pavlović, Stefan, Marinković, Dalibor, Kostić, Milan, Lončarević, Davor, Mojović, Ljiljana, Stanković, Miroslav, Veljković, Vlada B., "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production" in Fuel, 289 (2021):119912,
https://doi.org/10.1016/j.fuel.2020.119912 . .

TY  - JOUR
AU  - Pavlovic, Stefan M.
AU  - Marinkovic, Dalibor M.
AU  - Kostic, Milan D.
AU  - Loncarevic, Davor R.
AU  - Mojović, Ljiljana
AU  - Stankovic, Miroslav, V
AU  - Veljkovic, Vlada B.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4971
AB  - Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZM(FA)) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZM(FA) was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZM(FA) supported calcium oxide catalyst (xCaO/ZM(FA)) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5-20 wt%) over ZM(FA) and thermal treatment at different temperatures (450-600 degrees C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZM(FA) catalyst under reaction conditions: temperature of 60 degrees C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 degrees C. At calcination temperatures above 550 degrees C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.
T2  - Fuel
T1  - The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production
VL  - 289
DO  - 10.1016/j.fuel.2020.119912
ER  - 

@article{
author = "Pavlovic, Stefan M. and Marinkovic, Dalibor M. and Kostic, Milan D. and Loncarevic, Davor R. and Mojović, Ljiljana and Stankovic, Miroslav, V and Veljkovic, Vlada B.",
year = "2021",
abstract = "Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZM(FA)) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZM(FA) was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZM(FA) supported calcium oxide catalyst (xCaO/ZM(FA)) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5-20 wt%) over ZM(FA) and thermal treatment at different temperatures (450-600 degrees C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZM(FA) catalyst under reaction conditions: temperature of 60 degrees C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 degrees C. At calcination temperatures above 550 degrees C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.",
journal = "Fuel",
title = "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production",
volume = "289",
doi = "10.1016/j.fuel.2020.119912"
}

Pavlovic, S. M., Marinkovic, D. M., Kostic, M. D., Loncarevic, D. R., Mojović, L., Stankovic, M. V.,& Veljkovic, V. B.. (2021). The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel, 289.
https://doi.org/10.1016/j.fuel.2020.119912

Pavlovic SM, Marinkovic DM, Kostic MD, Loncarevic DR, Mojović L, Stankovic MV, Veljkovic VB. The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel. 2021;289.
doi:10.1016/j.fuel.2020.119912 .

Pavlovic, Stefan M., Marinkovic, Dalibor M., Kostic, Milan D., Loncarevic, Davor R., Mojović, Ljiljana, Stankovic, Miroslav, V, Veljkovic, Vlada B., "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production" in Fuel, 289 (2021),
https://doi.org/10.1016/j.fuel.2020.119912 . .

TY  - JOUR
AU  - Đorđević, Biljana S.
AU  - Troter, Dragan Z.
AU  - Veljković, Vlada B.
AU  - Kijevčanin, Mirjana
AU  - Radović, Ivona
AU  - Todorović, Zoran B.
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4427
AB  - Different deep eutectic solvents (DESs) of triethanolamine (TEOA) and oxalic acid (OA), glacial acetic acid (AA), L-(+)-lactic acid (LA), oleic acid (OLA), glycerol (G), ethylene glycol (EG), propylene glycol (PEG), choline chloride (ChCl) or 1,3-dimethylurea (DMU) were prepared and characterized regarding their physicochemical (density, viscosity, electrical conductivity, refractive index, coefficient of volume expansion, molecular volume, lattice energy and heat capacity) properties over the temperature range of 293.15-363.15 K at 101.325 kPa. For all tested DESs, the density, viscosity and refractive index decreased with rising temperature, while the electrical conductivity increased. The temperature dependence of viscosity and electrical conductivity are described by the Vogel-Tamman-Fulcher equations. The viscosity and molar conductivity, which exhibited a linear behaviour, were correlated by the fractional Walden rule. Besides, the Fourier transform infrared spectroscopy (FTIR) was used to study the functional groups of these DESs while thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) provided the information about their stability. The tested DESs of TEOA possess desirable properties for use in various industrial processes, such as extractions, separations, chemical technology and biotechnology.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - The physicochemical properties of the deep eutectic solvents with triethanolamine as a major component
EP  - 1315
IS  - 10
SP  - 1303
VL  - 85
DO  - 10.2298/JSC200425050D
ER  - 

@article{
author = "Đorđević, Biljana S. and Troter, Dragan Z. and Veljković, Vlada B. and Kijevčanin, Mirjana and Radović, Ivona and Todorović, Zoran B.",
year = "2020",
abstract = "Different deep eutectic solvents (DESs) of triethanolamine (TEOA) and oxalic acid (OA), glacial acetic acid (AA), L-(+)-lactic acid (LA), oleic acid (OLA), glycerol (G), ethylene glycol (EG), propylene glycol (PEG), choline chloride (ChCl) or 1,3-dimethylurea (DMU) were prepared and characterized regarding their physicochemical (density, viscosity, electrical conductivity, refractive index, coefficient of volume expansion, molecular volume, lattice energy and heat capacity) properties over the temperature range of 293.15-363.15 K at 101.325 kPa. For all tested DESs, the density, viscosity and refractive index decreased with rising temperature, while the electrical conductivity increased. The temperature dependence of viscosity and electrical conductivity are described by the Vogel-Tamman-Fulcher equations. The viscosity and molar conductivity, which exhibited a linear behaviour, were correlated by the fractional Walden rule. Besides, the Fourier transform infrared spectroscopy (FTIR) was used to study the functional groups of these DESs while thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) provided the information about their stability. The tested DESs of TEOA possess desirable properties for use in various industrial processes, such as extractions, separations, chemical technology and biotechnology.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "The physicochemical properties of the deep eutectic solvents with triethanolamine as a major component",
pages = "1315-1303",
number = "10",
volume = "85",
doi = "10.2298/JSC200425050D"
}

Đorđević, B. S., Troter, D. Z., Veljković, V. B., Kijevčanin, M., Radović, I.,& Todorović, Z. B.. (2020). The physicochemical properties of the deep eutectic solvents with triethanolamine as a major component. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 85(10), 1303-1315.
https://doi.org/10.2298/JSC200425050D

Đorđević BS, Troter DZ, Veljković VB, Kijevčanin M, Radović I, Todorović ZB. The physicochemical properties of the deep eutectic solvents with triethanolamine as a major component. in Journal of the Serbian Chemical Society. 2020;85(10):1303-1315.
doi:10.2298/JSC200425050D .

Đorđević, Biljana S., Troter, Dragan Z., Veljković, Vlada B., Kijevčanin, Mirjana, Radović, Ivona, Todorović, Zoran B., "The physicochemical properties of the deep eutectic solvents with triethanolamine as a major component" in Journal of the Serbian Chemical Society, 85, no. 10 (2020):1303-1315,
https://doi.org/10.2298/JSC200425050D . .