TY  - JOUR
AU  - Panczyszyn, Elzbieta
AU  - Saverio, Valentina
AU  - Monzani, Romina
AU  - Gagliardi, Mara
AU  - Petrović, Jelena
AU  - Stojkovska, Jasmina
AU  - Collavin, Licio
AU  - Corazzari, Marco
PY  - 2024-12
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7318
AB  - Human osteosarcoma (OS) is a relatively rare malignancy preferentially affecting long body bones which prognosis is often poor also due to the lack of effective therapies. Clinical management of this cancer basically relies on surgical removal of primary tumor coupled with radio/chemotherapy. Unfortunately, most osteosarcoma cells are resistant to conventional therapy, with the undergoing epithelial-mesenchymal transition (EMT) giving rise to gene expression reprogramming, thus increasing cancer cell invasiveness and metastatic potential. Alternative clinical approaches are thus urgently needed. In this context, the recently described ferroptotic cell death represents an attractive new strategy to efficiently kill cancer cells, since most chemoresistant and mesenchymal-shaped tumors display high susceptibility to pro-ferroptotic compounds. However, cancer cells have also evolved anti-ferroptotic strategies, which somehow sustain their survival upon ferroptosis induction. Indeed, here we show that osteosarcoma cell lines display heterogeneous sensitivity to ferroptosis execution, correlating with the mesenchymal phenotype, which is consistently affected by the expression of the well-known anti-ferroptotic factor ferroptosis suppressor protein 1 (FSP1). Interestingly, inhibiting the activity or expression of FSP1 restores cancer cell sensitivity to ferroptosis. Moreover, we also found that: i) AKRs might also contribute to resistance; ii) NRF2 enhances FSP1 expression upon ferroptosis induction; while iii) p53 contributes to the regulation of FSP1 basal expression in OS cells. In conclusion, FSP1 expression can potentially be used as a valuable predictive marker of OS sensitivity to ferroptosis and as a new potential therapeutic target.
PB  - Springer Nature
T2  - Cell Death Discovery
T1  - FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target
IS  - 1
SP  - 87
VL  - 10
DO  - 10.1038/s41420-024-01854-2
ER  - 

@article{
author = "Panczyszyn, Elzbieta and Saverio, Valentina and Monzani, Romina and Gagliardi, Mara and Petrović, Jelena and Stojkovska, Jasmina and Collavin, Licio and Corazzari, Marco",
year = "2024-12",
abstract = "Human osteosarcoma (OS) is a relatively rare malignancy preferentially affecting long body bones which prognosis is often poor also due to the lack of effective therapies. Clinical management of this cancer basically relies on surgical removal of primary tumor coupled with radio/chemotherapy. Unfortunately, most osteosarcoma cells are resistant to conventional therapy, with the undergoing epithelial-mesenchymal transition (EMT) giving rise to gene expression reprogramming, thus increasing cancer cell invasiveness and metastatic potential. Alternative clinical approaches are thus urgently needed. In this context, the recently described ferroptotic cell death represents an attractive new strategy to efficiently kill cancer cells, since most chemoresistant and mesenchymal-shaped tumors display high susceptibility to pro-ferroptotic compounds. However, cancer cells have also evolved anti-ferroptotic strategies, which somehow sustain their survival upon ferroptosis induction. Indeed, here we show that osteosarcoma cell lines display heterogeneous sensitivity to ferroptosis execution, correlating with the mesenchymal phenotype, which is consistently affected by the expression of the well-known anti-ferroptotic factor ferroptosis suppressor protein 1 (FSP1). Interestingly, inhibiting the activity or expression of FSP1 restores cancer cell sensitivity to ferroptosis. Moreover, we also found that: i) AKRs might also contribute to resistance; ii) NRF2 enhances FSP1 expression upon ferroptosis induction; while iii) p53 contributes to the regulation of FSP1 basal expression in OS cells. In conclusion, FSP1 expression can potentially be used as a valuable predictive marker of OS sensitivity to ferroptosis and as a new potential therapeutic target.",
publisher = "Springer Nature",
journal = "Cell Death Discovery",
title = "FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target",
number = "1",
pages = "87",
volume = "10",
doi = "10.1038/s41420-024-01854-2"
}

Panczyszyn, E., Saverio, V., Monzani, R., Gagliardi, M., Petrović, J., Stojkovska, J., Collavin, L.,& Corazzari, M.. (2024-12). FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target. in Cell Death Discovery
Springer Nature., 10(1), 87.
https://doi.org/10.1038/s41420-024-01854-2

Panczyszyn E, Saverio V, Monzani R, Gagliardi M, Petrović J, Stojkovska J, Collavin L, Corazzari M. FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target. in Cell Death Discovery. 2024;10(1):87.
doi:10.1038/s41420-024-01854-2 .

Panczyszyn, Elzbieta, Saverio, Valentina, Monzani, Romina, Gagliardi, Mara, Petrović, Jelena, Stojkovska, Jasmina, Collavin, Licio, Corazzari, Marco, "FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target" in Cell Death Discovery, 10, no. 1 (2024-12):87,
https://doi.org/10.1038/s41420-024-01854-2 . .

TY  - JOUR
AU  - Veljković, Milica
AU  - Banjanac, Katarina
AU  - Milivojević, Ana
AU  - Ćorović, Marija
AU  - Simović, Milica
AU  - Bezbradica, Dejan
PY  - 2024-08
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7425
AB  - Maple syrup, a popular natural sweetener has a high content of sucrose, whose consumption is linked to different health issues such as obesity and diabetes. Hence, within this paper, the conversion of sucrose to prebiotics (fructo-oligosaccharides, FOS) was proposed as a promising approach to obtaining a healthier, value-added product. Enzymatic conversion was optimized with respect to key experimental factors, and thereafter derived immobilized preparation of fructosyltransferase (FTase) from Pectinex® Ultra SP-L (FTase-epoxy Purolite, 255 IU/g support) was successfully utilized to produce novel functional product in ten consecutive reaction cycles. The product, obtained under optimal conditions (60 ◦C, 7.65 IU/mL, 12 h), resulted in 56.0% FOS, 16.7% sucrose, and 27.3% monosaccharides of total carbohydrates, leading to a 1.6-fold reduction in caloric content. The obtained products` prebiotic potential toward the probiotic strain Lactobacillus plantarum 299v was demonstrated. The changes in physico-chemical and sensorial characteristics were esteemed as negligible.
PB  - Elsevier Ltd.
T2  - Food Chemistry
T1  - Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides
SP  - 139180
VL  - 449
DO  - 10.1016/j.foodchem.2024.139180
ER  - 

@article{
author = "Veljković, Milica and Banjanac, Katarina and Milivojević, Ana and Ćorović, Marija and Simović, Milica and Bezbradica, Dejan",
year = "2024-08",
abstract = "Maple syrup, a popular natural sweetener has a high content of sucrose, whose consumption is linked to different health issues such as obesity and diabetes. Hence, within this paper, the conversion of sucrose to prebiotics (fructo-oligosaccharides, FOS) was proposed as a promising approach to obtaining a healthier, value-added product. Enzymatic conversion was optimized with respect to key experimental factors, and thereafter derived immobilized preparation of fructosyltransferase (FTase) from Pectinex® Ultra SP-L (FTase-epoxy Purolite, 255 IU/g support) was successfully utilized to produce novel functional product in ten consecutive reaction cycles. The product, obtained under optimal conditions (60 ◦C, 7.65 IU/mL, 12 h), resulted in 56.0% FOS, 16.7% sucrose, and 27.3% monosaccharides of total carbohydrates, leading to a 1.6-fold reduction in caloric content. The obtained products` prebiotic potential toward the probiotic strain Lactobacillus plantarum 299v was demonstrated. The changes in physico-chemical and sensorial characteristics were esteemed as negligible.",
publisher = "Elsevier Ltd.",
journal = "Food Chemistry",
title = "Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides",
pages = "139180",
volume = "449",
doi = "10.1016/j.foodchem.2024.139180"
}

Veljković, M., Banjanac, K., Milivojević, A., Ćorović, M., Simović, M.,& Bezbradica, D.. (2024-08). Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides. in Food Chemistry
Elsevier Ltd.., 449, 139180.
https://doi.org/10.1016/j.foodchem.2024.139180

Veljković M, Banjanac K, Milivojević A, Ćorović M, Simović M, Bezbradica D. Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides. in Food Chemistry. 2024;449:139180.
doi:10.1016/j.foodchem.2024.139180 .

Veljković, Milica, Banjanac, Katarina, Milivojević, Ana, Ćorović, Marija, Simović, Milica, Bezbradica, Dejan, "Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides" in Food Chemistry, 449 (2024-08):139180,
https://doi.org/10.1016/j.foodchem.2024.139180 . .

TY  - JOUR
AU  - Lazić, Anita
AU  - Radovanović, Lidija
AU  - Rogan, Jelena
AU  - Valentić, Nataša
AU  - Đorđević, Ivana
AU  - Trišović, Nemanja
PY  - 2024-08
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7435
AB  - Providing structural information on drug-like compounds is a significant step in efforts to develop innovative drugs with balanced solubility, cell permeability and target binding. In this paper, a new cyclohexane-5-spirohydantoin tethered with a 4‑tert-butylbenzoyl group was synthesized and its crystal structure was determined using the single crystal X-ray diffraction. The Hirshfeld surface analysis was used to gain a preliminary insight into the proportion and nature of the intermolecular interactions in the crystal structure, while their quantitative description is further presented in terms of a systematic analysis of dimeric motifs representing different recognition modes. A combination of N–H∙∙∙O and C(sp3)–H∙∙∙O hydrogen bonds, C(sp3)–H∙∙∙π, lone-pair∙∙∙π and π∙∙∙π stacking interactions links the molecules into a bilayer having two carbonyl O atoms exposed to the exterior. Further stacking of the bilayers occurs through C(sp3)–H∙∙∙O hydrogen bonds involving these O atoms as acceptors, C(sp3)–H∙∙∙π and π∙∙∙π stacking interactions between the phenyl groups. The molecular electrostatic potential surface map reveals that the carbonyl O atoms of the hydantoin ring and the phenyl ring are electrophilic centers, while the N1–H1 group is a nucleophilic center. The calculated HOMO and LUMO energies were used to semiquantitatively estimate the global reactivity descriptors suggesting the soft nature of the molecule.
PB  - Elsevier B.V.
T2  - Journal of Molecular Structure
T1  - Crystallographic and theoretical analysis of a spirohydantoin derivative: 3-(4‑tert-butylbenzoyl)-1,3-diazaspiro[4.5]decane-2,4‑dione
SP  - 138234
VL  - 1310
DO  - 10.1016/j.molstruc.2024.138234
ER  - 

@article{
author = "Lazić, Anita and Radovanović, Lidija and Rogan, Jelena and Valentić, Nataša and Đorđević, Ivana and Trišović, Nemanja",
year = "2024-08",
abstract = "Providing structural information on drug-like compounds is a significant step in efforts to develop innovative drugs with balanced solubility, cell permeability and target binding. In this paper, a new cyclohexane-5-spirohydantoin tethered with a 4‑tert-butylbenzoyl group was synthesized and its crystal structure was determined using the single crystal X-ray diffraction. The Hirshfeld surface analysis was used to gain a preliminary insight into the proportion and nature of the intermolecular interactions in the crystal structure, while their quantitative description is further presented in terms of a systematic analysis of dimeric motifs representing different recognition modes. A combination of N–H∙∙∙O and C(sp3)–H∙∙∙O hydrogen bonds, C(sp3)–H∙∙∙π, lone-pair∙∙∙π and π∙∙∙π stacking interactions links the molecules into a bilayer having two carbonyl O atoms exposed to the exterior. Further stacking of the bilayers occurs through C(sp3)–H∙∙∙O hydrogen bonds involving these O atoms as acceptors, C(sp3)–H∙∙∙π and π∙∙∙π stacking interactions between the phenyl groups. The molecular electrostatic potential surface map reveals that the carbonyl O atoms of the hydantoin ring and the phenyl ring are electrophilic centers, while the N1–H1 group is a nucleophilic center. The calculated HOMO and LUMO energies were used to semiquantitatively estimate the global reactivity descriptors suggesting the soft nature of the molecule.",
publisher = "Elsevier B.V.",
journal = "Journal of Molecular Structure",
title = "Crystallographic and theoretical analysis of a spirohydantoin derivative: 3-(4‑tert-butylbenzoyl)-1,3-diazaspiro[4.5]decane-2,4‑dione",
pages = "138234",
volume = "1310",
doi = "10.1016/j.molstruc.2024.138234"
}

Lazić, A., Radovanović, L., Rogan, J., Valentić, N., Đorđević, I.,& Trišović, N.. (2024-08). Crystallographic and theoretical analysis of a spirohydantoin derivative: 3-(4‑tert-butylbenzoyl)-1,3-diazaspiro[4.5]decane-2,4‑dione. in Journal of Molecular Structure
Elsevier B.V.., 1310, 138234.
https://doi.org/10.1016/j.molstruc.2024.138234

Lazić A, Radovanović L, Rogan J, Valentić N, Đorđević I, Trišović N. Crystallographic and theoretical analysis of a spirohydantoin derivative: 3-(4‑tert-butylbenzoyl)-1,3-diazaspiro[4.5]decane-2,4‑dione. in Journal of Molecular Structure. 2024;1310:138234.
doi:10.1016/j.molstruc.2024.138234 .

Lazić, Anita, Radovanović, Lidija, Rogan, Jelena, Valentić, Nataša, Đorđević, Ivana, Trišović, Nemanja, "Crystallographic and theoretical analysis of a spirohydantoin derivative: 3-(4‑tert-butylbenzoyl)-1,3-diazaspiro[4.5]decane-2,4‑dione" in Journal of Molecular Structure, 1310 (2024-08):138234,
https://doi.org/10.1016/j.molstruc.2024.138234 . .

TY  - JOUR
AU  - Tomić, Aleksandra
AU  - Pomeroy, Brett
AU  - Todić, Branislav
AU  - Likozar, Blaž
AU  - Nikačević, Nikola
PY  - 2024-07
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7452
AB  - The implementation of the liquid organic hydrogen carrier (LOHC) technology for efficient energy storage requires the development of a reliable kinetic model for both hydrogenation and dehydrogenation processes. In this research study, the catalytic hydrocarbon saturation for a dibenzyltoluene (DBT) mixture solution, containing dibenzylbenzene (DBB), dibenzylethylbenzene (DBEB) and impurities has been performed in the presence of Ru/Al2O3 particles. The influence of different reaction conditions, such as temperature, pressure, initial reactant concentration, catalyst amount and stirring speed has been examined. A measurement-based system micro-kinetics, based on the Langmuir–Hinshelwood mechanism with dissociative H2 surface adsorption, has been derived. H2 thermodynamic solubility equilibrium was defined through Henry's law. The adsorbing, desorption and reactivity of inert solvent molecules was not considered to be relevant. The mass transfer resistance over 1000 rpm stirring speed was negligible. Relative- and mean squared error of representation were 40.9% and 1.00×10−4, respectively. Expressions gave an excellent data prediction for the profile period trends with a relatively accurate estimation of H2 intermediates' rate selectivity, H2-covered area approximation and pathway rate-determining steps. Due to the lack of commercially available standard chemical compounds for quantitative analysis techniques, a novel experiment-based numerical calibration method was developed. Mean field (micro)kinetics represent an advancement in the mesoscale mechanistic understanding of physical interface phenomena. This also enables catalysis structure–activity relationships, unlocking the methodology for new LOHC reaching beyond traditional, such as ammonia, methanol and formate, which do not release H2 alone. Integrated multiscale simulations could include fluidics later on.
PB  - Elsevier Ltd.
T2  - Applied Energy
T1  - Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier
SP  - 123262
VL  - 365
DO  - 10.1016/j.apenergy.2024.123262
ER  - 

@article{
author = "Tomić, Aleksandra and Pomeroy, Brett and Todić, Branislav and Likozar, Blaž and Nikačević, Nikola",
year = "2024-07",
abstract = "The implementation of the liquid organic hydrogen carrier (LOHC) technology for efficient energy storage requires the development of a reliable kinetic model for both hydrogenation and dehydrogenation processes. In this research study, the catalytic hydrocarbon saturation for a dibenzyltoluene (DBT) mixture solution, containing dibenzylbenzene (DBB), dibenzylethylbenzene (DBEB) and impurities has been performed in the presence of Ru/Al2O3 particles. The influence of different reaction conditions, such as temperature, pressure, initial reactant concentration, catalyst amount and stirring speed has been examined. A measurement-based system micro-kinetics, based on the Langmuir–Hinshelwood mechanism with dissociative H2 surface adsorption, has been derived. H2 thermodynamic solubility equilibrium was defined through Henry's law. The adsorbing, desorption and reactivity of inert solvent molecules was not considered to be relevant. The mass transfer resistance over 1000 rpm stirring speed was negligible. Relative- and mean squared error of representation were 40.9% and 1.00×10−4, respectively. Expressions gave an excellent data prediction for the profile period trends with a relatively accurate estimation of H2 intermediates' rate selectivity, H2-covered area approximation and pathway rate-determining steps. Due to the lack of commercially available standard chemical compounds for quantitative analysis techniques, a novel experiment-based numerical calibration method was developed. Mean field (micro)kinetics represent an advancement in the mesoscale mechanistic understanding of physical interface phenomena. This also enables catalysis structure–activity relationships, unlocking the methodology for new LOHC reaching beyond traditional, such as ammonia, methanol and formate, which do not release H2 alone. Integrated multiscale simulations could include fluidics later on.",
publisher = "Elsevier Ltd.",
journal = "Applied Energy",
title = "Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier",
pages = "123262",
volume = "365",
doi = "10.1016/j.apenergy.2024.123262"
}

Tomić, A., Pomeroy, B., Todić, B., Likozar, B.,& Nikačević, N.. (2024-07). Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier. in Applied Energy
Elsevier Ltd.., 365, 123262.
https://doi.org/10.1016/j.apenergy.2024.123262

Tomić A, Pomeroy B, Todić B, Likozar B, Nikačević N. Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier. in Applied Energy. 2024;365:123262.
doi:10.1016/j.apenergy.2024.123262 .

Tomić, Aleksandra, Pomeroy, Brett, Todić, Branislav, Likozar, Blaž, Nikačević, Nikola, "Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier" in Applied Energy, 365 (2024-07):123262,
https://doi.org/10.1016/j.apenergy.2024.123262 . .

TY  - JOUR
AU  - Cvjetićanin, Milica
AU  - Ramić, Bojana
AU  - Milanović, Marija
AU  - Veljović, Đorđe
AU  - Anđelković, Aleksandar
AU  - Maletić, Snežana
AU  - Jevrosimov, Irina
AU  - Bajkin, Branislav
AU  - Gudurić, Vera
PY  - 2024-06
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7453
AB  - Objectives: To assess and compare the cell viability and ion release profiles of two conventional glass ionomer cements (GICs), Fuji IX and Ketac Molar EasyMix, modified with TiO2 and Mg-doped-HAp nanoparticles (NPs). Methods: TiO2 NPs, synthesized via a sol–gel method, and Mg-doped hydroxyapatite, synthesized via a hydrothermal process, were incorporated into GICs at a concentration of 5 wt.%. The biocompatibility of prepared materials was assessed by evaluating their effects on the viability of dental pulp stem cells (DPSCs), together with monitoring ion release profiles. Statistical analysis was performed using One-way analysis of variance, with significance level p < 0.05. Results: The addition of NPs did not significantly affect the biocompatibility of GICs, as evidenced by comparable decreased levels in cell viability to their original formulations. Distinct variations in cell viability were observed among Fuji IX and Ketac Molar, including their respective modifications. FUJI IX and its modification with TiO2 exhibited moderate decrease in cell viability, while other groups exhibited severe negative effects. While slight differences in ion release profiles were observed among the groups, significant variations compared to original cements were not achieved. Fluoride release exhibited an initial “burst release” within the initial 24 h in all samples, stabilizing over subsequent days. Conclusions: The addition of NPs did not compromise biocompatibility, nor anticariogenic potential of tested GICs. However, observed differences among FUJI IX and Ketac Molar, including their respective modifications, as well as induced low viability of DPSC by all tested groups, suggest the need for careful consideration of cement composition in their biological assessments. Clinical significance: The findings contribute to understanding the complex interaction between NPs and GIC matrices. However, the results should be interpreted recognizing the inherent limitations associated with in vitro studies. Further research avenues could explore long-term effects, in vivo performance, and potential clinical applications.
PB  - Elsevier Ltd.
T2  - Journal of Dentistry
T1  - Cell viability assessment and ion release profiles of GICs modified with TiO2- and Mg-doped hydroxyapatite nanoparticles
SP  - 105015
VL  - 145
DO  - 10.1016/j.jdent.2024.105015
ER  - 

@article{
author = "Cvjetićanin, Milica and Ramić, Bojana and Milanović, Marija and Veljović, Đorđe and Anđelković, Aleksandar and Maletić, Snežana and Jevrosimov, Irina and Bajkin, Branislav and Gudurić, Vera",
year = "2024-06",
abstract = "Objectives: To assess and compare the cell viability and ion release profiles of two conventional glass ionomer cements (GICs), Fuji IX and Ketac Molar EasyMix, modified with TiO2 and Mg-doped-HAp nanoparticles (NPs). Methods: TiO2 NPs, synthesized via a sol–gel method, and Mg-doped hydroxyapatite, synthesized via a hydrothermal process, were incorporated into GICs at a concentration of 5 wt.%. The biocompatibility of prepared materials was assessed by evaluating their effects on the viability of dental pulp stem cells (DPSCs), together with monitoring ion release profiles. Statistical analysis was performed using One-way analysis of variance, with significance level p < 0.05. Results: The addition of NPs did not significantly affect the biocompatibility of GICs, as evidenced by comparable decreased levels in cell viability to their original formulations. Distinct variations in cell viability were observed among Fuji IX and Ketac Molar, including their respective modifications. FUJI IX and its modification with TiO2 exhibited moderate decrease in cell viability, while other groups exhibited severe negative effects. While slight differences in ion release profiles were observed among the groups, significant variations compared to original cements were not achieved. Fluoride release exhibited an initial “burst release” within the initial 24 h in all samples, stabilizing over subsequent days. Conclusions: The addition of NPs did not compromise biocompatibility, nor anticariogenic potential of tested GICs. However, observed differences among FUJI IX and Ketac Molar, including their respective modifications, as well as induced low viability of DPSC by all tested groups, suggest the need for careful consideration of cement composition in their biological assessments. Clinical significance: The findings contribute to understanding the complex interaction between NPs and GIC matrices. However, the results should be interpreted recognizing the inherent limitations associated with in vitro studies. Further research avenues could explore long-term effects, in vivo performance, and potential clinical applications.",
publisher = "Elsevier Ltd.",
journal = "Journal of Dentistry",
title = "Cell viability assessment and ion release profiles of GICs modified with TiO2- and Mg-doped hydroxyapatite nanoparticles",
pages = "105015",
volume = "145",
doi = "10.1016/j.jdent.2024.105015"
}

Cvjetićanin, M., Ramić, B., Milanović, M., Veljović, Đ., Anđelković, A., Maletić, S., Jevrosimov, I., Bajkin, B.,& Gudurić, V.. (2024-06). Cell viability assessment and ion release profiles of GICs modified with TiO2- and Mg-doped hydroxyapatite nanoparticles. in Journal of Dentistry
Elsevier Ltd.., 145, 105015.
https://doi.org/10.1016/j.jdent.2024.105015

Cvjetićanin M, Ramić B, Milanović M, Veljović Đ, Anđelković A, Maletić S, Jevrosimov I, Bajkin B, Gudurić V. Cell viability assessment and ion release profiles of GICs modified with TiO2- and Mg-doped hydroxyapatite nanoparticles. in Journal of Dentistry. 2024;145:105015.
doi:10.1016/j.jdent.2024.105015 .

Cvjetićanin, Milica, Ramić, Bojana, Milanović, Marija, Veljović, Đorđe, Anđelković, Aleksandar, Maletić, Snežana, Jevrosimov, Irina, Bajkin, Branislav, Gudurić, Vera, "Cell viability assessment and ion release profiles of GICs modified with TiO2- and Mg-doped hydroxyapatite nanoparticles" in Journal of Dentistry, 145 (2024-06):105015,
https://doi.org/10.1016/j.jdent.2024.105015 . .

TY  - JOUR
AU  - Ayub, Hafiz Muhammad Uzair
AU  - Alnouri, Sabla Y.
AU  - Stijepović, Mirko
AU  - Stijepović, Vladimir
AU  - Hussein, Ibnelwaleed A.
PY  - 2024-06
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7449
AB  - Energy systems are undergoing rapid change as the world responds to climate change. Many policymakers may ask, what will be the next great energy source for a low-carbon future? All indications so far point to hydrogen energy. Although it is anticipated that costs will likely fall as the hydrogen production scale increases, it may be reported that the high technology costs remain a barrier to the widespread shift towards hydrogen. This paper presents hydrogen production costs for various production methods for different regions across the world, including the USA, the Middle East, Europe, India, and Canada. The costs of hydrogen production from biomass gasification, coal gasification, and natural gas reforming are compared, revealing the varying costs across different regions. Moreover, the production of green hydrogen from renewable energy sources is also presented, and compared with conventional methods. It highlights that while green hydrogen is environmentally sustainable, its production remains cost-intensive compared to integrated processes. Notably, the Middle East and India demonstrate the most economical production costs for both electrolysis and nuclear-based processes, while Europe shows the highest costs. The information presented in this paper could be helpful for researchers and policymakers to make informed decisions regarding the necessary aspects that still need to be investigated, to help with the transition into a hydrogen energy future.
PB  - Institution of Chemical Engineers
T2  - Process Safety and Environmental Protection
T1  - A cost comparison study for hydrogen production between conventional and renewable methods
EP  - 932
SP  - 921
VL  - 186
DO  - 10.1016/j.psep.2024.04.080
ER  - 

@article{
author = "Ayub, Hafiz Muhammad Uzair and Alnouri, Sabla Y. and Stijepović, Mirko and Stijepović, Vladimir and Hussein, Ibnelwaleed A.",
year = "2024-06",
abstract = "Energy systems are undergoing rapid change as the world responds to climate change. Many policymakers may ask, what will be the next great energy source for a low-carbon future? All indications so far point to hydrogen energy. Although it is anticipated that costs will likely fall as the hydrogen production scale increases, it may be reported that the high technology costs remain a barrier to the widespread shift towards hydrogen. This paper presents hydrogen production costs for various production methods for different regions across the world, including the USA, the Middle East, Europe, India, and Canada. The costs of hydrogen production from biomass gasification, coal gasification, and natural gas reforming are compared, revealing the varying costs across different regions. Moreover, the production of green hydrogen from renewable energy sources is also presented, and compared with conventional methods. It highlights that while green hydrogen is environmentally sustainable, its production remains cost-intensive compared to integrated processes. Notably, the Middle East and India demonstrate the most economical production costs for both electrolysis and nuclear-based processes, while Europe shows the highest costs. The information presented in this paper could be helpful for researchers and policymakers to make informed decisions regarding the necessary aspects that still need to be investigated, to help with the transition into a hydrogen energy future.",
publisher = "Institution of Chemical Engineers",
journal = "Process Safety and Environmental Protection",
title = "A cost comparison study for hydrogen production between conventional and renewable methods",
pages = "932-921",
volume = "186",
doi = "10.1016/j.psep.2024.04.080"
}

Ayub, H. M. U., Alnouri, S. Y., Stijepović, M., Stijepović, V.,& Hussein, I. A.. (2024-06). A cost comparison study for hydrogen production between conventional and renewable methods. in Process Safety and Environmental Protection
Institution of Chemical Engineers., 186, 921-932.
https://doi.org/10.1016/j.psep.2024.04.080

Ayub HMU, Alnouri SY, Stijepović M, Stijepović V, Hussein IA. A cost comparison study for hydrogen production between conventional and renewable methods. in Process Safety and Environmental Protection. 2024;186:921-932.
doi:10.1016/j.psep.2024.04.080 .

Ayub, Hafiz Muhammad Uzair, Alnouri, Sabla Y., Stijepović, Mirko, Stijepović, Vladimir, Hussein, Ibnelwaleed A., "A cost comparison study for hydrogen production between conventional and renewable methods" in Process Safety and Environmental Protection, 186 (2024-06):921-932,
https://doi.org/10.1016/j.psep.2024.04.080 . .

TY  - JOUR
AU  - Perović, Milica N.
AU  - Knežević Jugović, Zorica D.
AU  - Antov, Mirjana G.
PY  - 2024-06
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7257
AB  - Nanoparticles  prepared by heat treatment of protein from pumpkin leaves were evaluated as potential carriers of β-carotene. White protein fraction was recovered from green juice produced by pressing the leaves, with the step of enzyme-assisted extraction (green protocol) or without it (conventional protocol). Heat treatment of white protein fractions from conventional and green protocols at 90 °C and pH 9.3 during 20 min induced formation of nanoparticles with peak diameter 18 nm and 21 nm, respectively. Due to heating, portion of β-sheets in nanoparticles from both native protein fractions decreased by approximately 15 %, associated with an increase in surface hydrophobicity-to-area ratio. Quenching constant of β-carotene for nanoparticles was increased nearly 100 times by heating the white protein fraction recovered in green protocol. Native white protein fraction from conventional protocol and corresponding nanoparticles exhibited high ability to bind β-carotene, with quenching constant 3 × 105 L/mol and 3.3 × 105 L/mol, respectively. White protein fraction from pumpkin leaves appeared to be a suitable substrate for the fabrication of nanoparticles by heat treatment, with potential application as β-carotene nanocarriers in food matrices.
PB  - Elsevier B.V.
T2  - Future Foods
T1  - Heat-induced nanoparticles from pumpkin leaf protein for potential application as β-carotene carriers
SP  - 100310
VL  - 9
DO  - 10.1016/j.fufo.2024.100310
ER  - 

@article{
author = "Perović, Milica N. and Knežević Jugović, Zorica D. and Antov, Mirjana G.",
year = "2024-06",
abstract = "Nanoparticles  prepared by heat treatment of protein from pumpkin leaves were evaluated as potential carriers of β-carotene. White protein fraction was recovered from green juice produced by pressing the leaves, with the step of enzyme-assisted extraction (green protocol) or without it (conventional protocol). Heat treatment of white protein fractions from conventional and green protocols at 90 °C and pH 9.3 during 20 min induced formation of nanoparticles with peak diameter 18 nm and 21 nm, respectively. Due to heating, portion of β-sheets in nanoparticles from both native protein fractions decreased by approximately 15 %, associated with an increase in surface hydrophobicity-to-area ratio. Quenching constant of β-carotene for nanoparticles was increased nearly 100 times by heating the white protein fraction recovered in green protocol. Native white protein fraction from conventional protocol and corresponding nanoparticles exhibited high ability to bind β-carotene, with quenching constant 3 × 105 L/mol and 3.3 × 105 L/mol, respectively. White protein fraction from pumpkin leaves appeared to be a suitable substrate for the fabrication of nanoparticles by heat treatment, with potential application as β-carotene nanocarriers in food matrices.",
publisher = "Elsevier B.V.",
journal = "Future Foods",
title = "Heat-induced nanoparticles from pumpkin leaf protein for potential application as β-carotene carriers",
pages = "100310",
volume = "9",
doi = "10.1016/j.fufo.2024.100310"
}

Perović, M. N., Knežević Jugović, Z. D.,& Antov, M. G.. (2024-06). Heat-induced nanoparticles from pumpkin leaf protein for potential application as β-carotene carriers. in Future Foods
Elsevier B.V.., 9, 100310.
https://doi.org/10.1016/j.fufo.2024.100310

Perović MN, Knežević Jugović ZD, Antov MG. Heat-induced nanoparticles from pumpkin leaf protein for potential application as β-carotene carriers. in Future Foods. 2024;9:100310.
doi:10.1016/j.fufo.2024.100310 .

Perović, Milica N., Knežević Jugović, Zorica D., Antov, Mirjana G., "Heat-induced nanoparticles from pumpkin leaf protein for potential application as β-carotene carriers" in Future Foods, 9 (2024-06):100310,
https://doi.org/10.1016/j.fufo.2024.100310 . .

Maksimović, A., Milović, L., Zečević, B., Aleksić, V.,& Bekrić, D.. (2024-06). Determination of the ductile-to-brittle transition temperature of NIOMOL 490 K steel welded joints. in Theoretical and Applied Fracture Mechanics
Elsevier B.V.., 131, 104404.
https://doi.org/10.1016/j.tafmec.2024.104404

Maksimović A, Milović L, Zečević B, Aleksić V, Bekrić D. Determination of the ductile-to-brittle transition temperature of NIOMOL 490 K steel welded joints. in Theoretical and Applied Fracture Mechanics. 2024;131:104404.
doi:10.1016/j.tafmec.2024.104404 .

Maksimović, Ana, Milović, Ljubica, Zečević, Bojana, Aleksić, Vujadin, Bekrić, Dragoljub, "Determination of the ductile-to-brittle transition temperature of NIOMOL 490 K steel welded joints" in Theoretical and Applied Fracture Mechanics, 131 (2024-06):104404,
https://doi.org/10.1016/j.tafmec.2024.104404 . .

TY  - JOUR
AU  - Aranđelović, Mihajlo
AU  - Đorđević, Branislav
AU  - Sedmak, Simon
AU  - Radu, Dorin
AU  - Petrović, Ana
AU  - Dikić, Stefan
AU  - Sedmak, Aleksandar
PY  - 2024-06
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7360
AB  - Failure analysis of welded joint with multiple defects was performed taking into account the effect of all defects, not just a dominant one. Four cases of multiple defects in welded joint under the uniaxial tensile loading were investigated using extended Finite Element Method. Two-dimensional Finite Element Models were made according to the tensile specimens with initial crack located in a critical area of welded joint. For each multiple defects case, numerical simulation was performed with three initial crack depth. Engineering Critical Analysis was made using Failure Assessment Diagrams for each defect that was determined as critical for its welded joint case. Numerical simulation showed that the geometry of the most prominent one from a point of view of structural integrity. It was concluded that the vertical misalignment in combination with a secondary defect, had the most adverse effect which can lead to failure of welded structure.
PB  - Elsevier Ltd.
T2  - Engineering Failure Analysis
T1  - Failure analysis of welded joint with multiple defects by extended Finite Element Method and Engineering Critical Analysis
SP  - 108176
VL  - 160
DO  - 10.1016/j.engfailanal.2024.108176
ER  - 

@article{
author = "Aranđelović, Mihajlo and Đorđević, Branislav and Sedmak, Simon and Radu, Dorin and Petrović, Ana and Dikić, Stefan and Sedmak, Aleksandar",
year = "2024-06",
abstract = "Failure analysis of welded joint with multiple defects was performed taking into account the effect of all defects, not just a dominant one. Four cases of multiple defects in welded joint under the uniaxial tensile loading were investigated using extended Finite Element Method. Two-dimensional Finite Element Models were made according to the tensile specimens with initial crack located in a critical area of welded joint. For each multiple defects case, numerical simulation was performed with three initial crack depth. Engineering Critical Analysis was made using Failure Assessment Diagrams for each defect that was determined as critical for its welded joint case. Numerical simulation showed that the geometry of the most prominent one from a point of view of structural integrity. It was concluded that the vertical misalignment in combination with a secondary defect, had the most adverse effect which can lead to failure of welded structure.",
publisher = "Elsevier Ltd.",
journal = "Engineering Failure Analysis",
title = "Failure analysis of welded joint with multiple defects by extended Finite Element Method and Engineering Critical Analysis",
pages = "108176",
volume = "160",
doi = "10.1016/j.engfailanal.2024.108176"
}

Aranđelović, M., Đorđević, B., Sedmak, S., Radu, D., Petrović, A., Dikić, S.,& Sedmak, A.. (2024-06). Failure analysis of welded joint with multiple defects by extended Finite Element Method and Engineering Critical Analysis. in Engineering Failure Analysis
Elsevier Ltd.., 160, 108176.
https://doi.org/10.1016/j.engfailanal.2024.108176

Aranđelović M, Đorđević B, Sedmak S, Radu D, Petrović A, Dikić S, Sedmak A. Failure analysis of welded joint with multiple defects by extended Finite Element Method and Engineering Critical Analysis. in Engineering Failure Analysis. 2024;160:108176.
doi:10.1016/j.engfailanal.2024.108176 .

Aranđelović, Mihajlo, Đorđević, Branislav, Sedmak, Simon, Radu, Dorin, Petrović, Ana, Dikić, Stefan, Sedmak, Aleksandar, "Failure analysis of welded joint with multiple defects by extended Finite Element Method and Engineering Critical Analysis" in Engineering Failure Analysis, 160 (2024-06):108176,
https://doi.org/10.1016/j.engfailanal.2024.108176 . .

TY  - JOUR
AU  - Radulović, Jelena
AU  - Lučić, Milica
AU  - Onjia, Antonije
PY  - 2024-05
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7361
AB  - Pesticides used in coffee cultivation may remain behind and pose a risk to humans even after various processing stages of coffee beans (washing, drying, roasting, and grinding). In addition to pesticides applied to battle pests and diseases, mepiquat formation occurs during roasting. A comprehensive LC-MS/MS and GC-MS/MS multi-residue screening approach to determine pesticides in coffee was used in this study. Residues were extracted using the QuEChERS method and analyzed using multiple reaction monitoring (MRM) mass spectrometry after chromatographic separations. Good linearity (r2˃0.9919), recovery (80.2–118%), and RSD (≤19%) were obtained for the procedure including sample preparation and both instrumental techniques. Nine residues were identified as commonly present in coffee samples collected from supermarkets in Serbia. The human intake risk of pesticides was categorized and prioritized using the matrix ranking scheme. Also, health risk assessment was conducted by calculating acute and chronic hazard indices. Multi-residues were present in 79.2% of samples, whereas mepiquat chloride (88.9%) and permethrin (81.9%) were the most detected residues. Risk ranking classified mepiquat chloride, permethrin, and methiocarb sulfone in a high-risk group. On the other hand, the human health risk assessment indicated no risks in the short- and long-term and no cumulative chronic risk.
PB  - Academic Press Inc.
T2  - Journal of Food Composition and Analysis
T1  - GC-MS/MS and LC-MS/MS analysis followed by risk ranking of mepiquat and pyrethroids in coffee
SP  - 106100
VL  - 129
DO  - 10.1016/j.jfca.2024.106100
ER  - 

@article{
author = "Radulović, Jelena and Lučić, Milica and Onjia, Antonije",
year = "2024-05",
abstract = "Pesticides used in coffee cultivation may remain behind and pose a risk to humans even after various processing stages of coffee beans (washing, drying, roasting, and grinding). In addition to pesticides applied to battle pests and diseases, mepiquat formation occurs during roasting. A comprehensive LC-MS/MS and GC-MS/MS multi-residue screening approach to determine pesticides in coffee was used in this study. Residues were extracted using the QuEChERS method and analyzed using multiple reaction monitoring (MRM) mass spectrometry after chromatographic separations. Good linearity (r2˃0.9919), recovery (80.2–118%), and RSD (≤19%) were obtained for the procedure including sample preparation and both instrumental techniques. Nine residues were identified as commonly present in coffee samples collected from supermarkets in Serbia. The human intake risk of pesticides was categorized and prioritized using the matrix ranking scheme. Also, health risk assessment was conducted by calculating acute and chronic hazard indices. Multi-residues were present in 79.2% of samples, whereas mepiquat chloride (88.9%) and permethrin (81.9%) were the most detected residues. Risk ranking classified mepiquat chloride, permethrin, and methiocarb sulfone in a high-risk group. On the other hand, the human health risk assessment indicated no risks in the short- and long-term and no cumulative chronic risk.",
publisher = "Academic Press Inc.",
journal = "Journal of Food Composition and Analysis",
title = "GC-MS/MS and LC-MS/MS analysis followed by risk ranking of mepiquat and pyrethroids in coffee",
pages = "106100",
volume = "129",
doi = "10.1016/j.jfca.2024.106100"
}

Radulović, J., Lučić, M.,& Onjia, A.. (2024-05). GC-MS/MS and LC-MS/MS analysis followed by risk ranking of mepiquat and pyrethroids in coffee. in Journal of Food Composition and Analysis
Academic Press Inc.., 129, 106100.
https://doi.org/10.1016/j.jfca.2024.106100

Radulović J, Lučić M, Onjia A. GC-MS/MS and LC-MS/MS analysis followed by risk ranking of mepiquat and pyrethroids in coffee. in Journal of Food Composition and Analysis. 2024;129:106100.
doi:10.1016/j.jfca.2024.106100 .

Radulović, Jelena, Lučić, Milica, Onjia, Antonije, "GC-MS/MS and LC-MS/MS analysis followed by risk ranking of mepiquat and pyrethroids in coffee" in Journal of Food Composition and Analysis, 129 (2024-05):106100,
https://doi.org/10.1016/j.jfca.2024.106100 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Janković-Častvan, Ivona
AU  - Lukić, Ivana
PY  - 2024-05
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7258
AB  - This study focuses on the development of bioactive materials using environmentally friendly techniques, renewable, biocompatible, and biodegradable polysaccharide, as well as natural bioactive compounds (NBCs) found in plant extracts. First, cornstarch aerogels with a porosity of 86 % and a specific surface area of 225 m2/g were produced via supercritical CO2- assisted drying. Further, thymol, citronellol, carvacrol, and eugenol were incorporated into the aerogels by supercritical CO2- assisted impregnation, which allowed variation in loadings of NBCs (12.8–17.6 %). Interaction between cornstarch aerogels and NBCs determined impregnation rate, pore wall thickness (in the range 18–95 nm), liquid absorption capacity (from 265 to 569 %), dehydration mass loss, and release in phosphate-buffered saline. Controlled release of NBCs was maintained over a 3-day period. Moreover, impregnated aerogels showed a significant antioxidant effect with the highest value for DPPH radical inhibition of 25.5 % determined for the aerogels impregnated with eugenol. Notable antimicrobial activity against tested Gram-negative bacteria, Gram-positive bacteria, and fungi was also observed, being the highest for thymol-loaded aerogel with the diameter of the inhibition zones of up to 37.5 mm. This work shows a promising green approach for the production of bioactive two-component starch-based materials for potential applications in skin infection treatment.
PB  - Elsevier Ltd.
T2  - Carbohydrate Polymers
T1  - Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications
SP  - 121874
VL  - 331
DO  - 10.1016/j.carbpol.2024.121874
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Janković-Častvan, Ivona and Lukić, Ivana",
year = "2024-05",
abstract = "This study focuses on the development of bioactive materials using environmentally friendly techniques, renewable, biocompatible, and biodegradable polysaccharide, as well as natural bioactive compounds (NBCs) found in plant extracts. First, cornstarch aerogels with a porosity of 86 % and a specific surface area of 225 m2/g were produced via supercritical CO2- assisted drying. Further, thymol, citronellol, carvacrol, and eugenol were incorporated into the aerogels by supercritical CO2- assisted impregnation, which allowed variation in loadings of NBCs (12.8–17.6 %). Interaction between cornstarch aerogels and NBCs determined impregnation rate, pore wall thickness (in the range 18–95 nm), liquid absorption capacity (from 265 to 569 %), dehydration mass loss, and release in phosphate-buffered saline. Controlled release of NBCs was maintained over a 3-day period. Moreover, impregnated aerogels showed a significant antioxidant effect with the highest value for DPPH radical inhibition of 25.5 % determined for the aerogels impregnated with eugenol. Notable antimicrobial activity against tested Gram-negative bacteria, Gram-positive bacteria, and fungi was also observed, being the highest for thymol-loaded aerogel with the diameter of the inhibition zones of up to 37.5 mm. This work shows a promising green approach for the production of bioactive two-component starch-based materials for potential applications in skin infection treatment.",
publisher = "Elsevier Ltd.",
journal = "Carbohydrate Polymers",
title = "Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications",
pages = "121874",
volume = "331",
doi = "10.1016/j.carbpol.2024.121874"
}

Milovanović, S., Marković, D., Janković-Častvan, I.,& Lukić, I.. (2024-05). Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications. in Carbohydrate Polymers
Elsevier Ltd.., 331, 121874.
https://doi.org/10.1016/j.carbpol.2024.121874

Milovanović S, Marković D, Janković-Častvan I, Lukić I. Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications. in Carbohydrate Polymers. 2024;331:121874.
doi:10.1016/j.carbpol.2024.121874 .

Milovanović, Stoja, Marković, Darka, Janković-Častvan, Ivona, Lukić, Ivana, "Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications" in Carbohydrate Polymers, 331 (2024-05):121874,
https://doi.org/10.1016/j.carbpol.2024.121874 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Lukić, Ivana
AU  - Krgović, Nemanja
AU  - Tadić, Vanja
AU  - Radovanović, Željko
AU  - Tyśkiewicz, Katarzyna
AU  - Konkol, Marcin
PY  - 2024-04
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7140
AB  - The study aimed toward the development of biocompatible and biodegradable polymeric films (starch-chitosan and starch-chitosan-cyclodextrin) with biologically valuable green tea leaf extract using an environmentally friendly integrated process of supercritical fluid extraction (SFE) and supercritical solvent impregnation (SSI). The SFE-SSI process parameters were selected through the initial estimation of the SFE parameters effect (temperatures 35 and 70 °C and the addition of co-solvents ethanol, ethanol/water, and water). The present early-stage work showed that an increase in temperature increased extraction yield (from 0.9 to 4.2%) and caffeine content while it decreased polyphenolic and pigment content as well as antioxidant activity and extract loading onto films (from 7.1 to 0.1%). The addition of co-solvents to sc-CO2 had an adverse effect on extract yield, composition, and loading. The highest recorded total phenolic, flavonoid, chlorophyll A, and caffeine content in extracts were 136.5 mg GE/g, 22.7 mg RE/g, 8.1 mg/g, and 460.0 mg/g, respectively.
PB  - Elsevier B.V.
T2  - Journal of Supercritical Fluids
T1  - Selection of processing parameters for the integrated supercritical CO2 extraction from green tea leaves and extract impregnation onto starch-chitosan based films
SP  - 106163
VL  - 206
DO  - 10.1016/j.supflu.2023.106163
ER  - 

@article{
author = "Milovanović, Stoja and Lukić, Ivana and Krgović, Nemanja and Tadić, Vanja and Radovanović, Željko and Tyśkiewicz, Katarzyna and Konkol, Marcin",
year = "2024-04",
abstract = "The study aimed toward the development of biocompatible and biodegradable polymeric films (starch-chitosan and starch-chitosan-cyclodextrin) with biologically valuable green tea leaf extract using an environmentally friendly integrated process of supercritical fluid extraction (SFE) and supercritical solvent impregnation (SSI). The SFE-SSI process parameters were selected through the initial estimation of the SFE parameters effect (temperatures 35 and 70 °C and the addition of co-solvents ethanol, ethanol/water, and water). The present early-stage work showed that an increase in temperature increased extraction yield (from 0.9 to 4.2%) and caffeine content while it decreased polyphenolic and pigment content as well as antioxidant activity and extract loading onto films (from 7.1 to 0.1%). The addition of co-solvents to sc-CO2 had an adverse effect on extract yield, composition, and loading. The highest recorded total phenolic, flavonoid, chlorophyll A, and caffeine content in extracts were 136.5 mg GE/g, 22.7 mg RE/g, 8.1 mg/g, and 460.0 mg/g, respectively.",
publisher = "Elsevier B.V.",
journal = "Journal of Supercritical Fluids",
title = "Selection of processing parameters for the integrated supercritical CO2 extraction from green tea leaves and extract impregnation onto starch-chitosan based films",
pages = "106163",
volume = "206",
doi = "10.1016/j.supflu.2023.106163"
}

Milovanović, S., Lukić, I., Krgović, N., Tadić, V., Radovanović, Ž., Tyśkiewicz, K.,& Konkol, M.. (2024-04). Selection of processing parameters for the integrated supercritical CO2 extraction from green tea leaves and extract impregnation onto starch-chitosan based films. in Journal of Supercritical Fluids
Elsevier B.V.., 206, 106163.
https://doi.org/10.1016/j.supflu.2023.106163

Milovanović S, Lukić I, Krgović N, Tadić V, Radovanović Ž, Tyśkiewicz K, Konkol M. Selection of processing parameters for the integrated supercritical CO2 extraction from green tea leaves and extract impregnation onto starch-chitosan based films. in Journal of Supercritical Fluids. 2024;206:106163.
doi:10.1016/j.supflu.2023.106163 .

Milovanović, Stoja, Lukić, Ivana, Krgović, Nemanja, Tadić, Vanja, Radovanović, Željko, Tyśkiewicz, Katarzyna, Konkol, Marcin, "Selection of processing parameters for the integrated supercritical CO2 extraction from green tea leaves and extract impregnation onto starch-chitosan based films" in Journal of Supercritical Fluids, 206 (2024-04):106163,
https://doi.org/10.1016/j.supflu.2023.106163 . .

TY  - JOUR
AU  - Borović, Teona Teodora
AU  - Panić, Jovana
AU  - Radović, Ivona
AU  - Grozdanić, Nikola
AU  - Vraneš, Milan
PY  - 2024-03
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7188
AB  - In this study, a detailed physicochemical characterization of caffeine in 0.1 mol∙kg−1 of 1-butyl-3-methylimidazolium salicylate (abbreviation [Bmim][Sal]) aqueous solutions is performed based on density, speed of sound, refractive index and viscosity measurements in the temperature range from T = (293.15–313.15) K. [Bmim][Sal] slightly increases the solubility of caffeine in water. Data obtained from the volumetric and viscosimetric measurements indicate that [Bmim][Sal] promotes the self-aggregation of caffeine in water. Molecular dynamic simulations provided insight into how [Bmim][Sal] increases caffeine solubility in water. At higher temperatures, the salicylate anion has stronger interactions with caffeine through π–π interactions than at lower temperatures.
PB  - Elsevier B.V.
T2  - Journal of Molecular Liquids
T1  - Interactions of caffeine and 1-butyl-3-methylimidazolium salicylate ionic liquid in water – Solubility, volumetric, acoustic, viscometric and refractometric studies supported by MD simulation
SP  - 124058
VL  - 397
DO  - 10.1016/j.molliq.2024.124058
ER  - 

@article{
author = "Borović, Teona Teodora and Panić, Jovana and Radović, Ivona and Grozdanić, Nikola and Vraneš, Milan",
year = "2024-03",
abstract = "In this study, a detailed physicochemical characterization of caffeine in 0.1 mol∙kg−1 of 1-butyl-3-methylimidazolium salicylate (abbreviation [Bmim][Sal]) aqueous solutions is performed based on density, speed of sound, refractive index and viscosity measurements in the temperature range from T = (293.15–313.15) K. [Bmim][Sal] slightly increases the solubility of caffeine in water. Data obtained from the volumetric and viscosimetric measurements indicate that [Bmim][Sal] promotes the self-aggregation of caffeine in water. Molecular dynamic simulations provided insight into how [Bmim][Sal] increases caffeine solubility in water. At higher temperatures, the salicylate anion has stronger interactions with caffeine through π–π interactions than at lower temperatures.",
publisher = "Elsevier B.V.",
journal = "Journal of Molecular Liquids",
title = "Interactions of caffeine and 1-butyl-3-methylimidazolium salicylate ionic liquid in water – Solubility, volumetric, acoustic, viscometric and refractometric studies supported by MD simulation",
pages = "124058",
volume = "397",
doi = "10.1016/j.molliq.2024.124058"
}

Borović, T. T., Panić, J., Radović, I., Grozdanić, N.,& Vraneš, M.. (2024-03). Interactions of caffeine and 1-butyl-3-methylimidazolium salicylate ionic liquid in water – Solubility, volumetric, acoustic, viscometric and refractometric studies supported by MD simulation. in Journal of Molecular Liquids
Elsevier B.V.., 397, 124058.
https://doi.org/10.1016/j.molliq.2024.124058

Borović TT, Panić J, Radović I, Grozdanić N, Vraneš M. Interactions of caffeine and 1-butyl-3-methylimidazolium salicylate ionic liquid in water – Solubility, volumetric, acoustic, viscometric and refractometric studies supported by MD simulation. in Journal of Molecular Liquids. 2024;397:124058.
doi:10.1016/j.molliq.2024.124058 .

Borović, Teona Teodora, Panić, Jovana, Radović, Ivona, Grozdanić, Nikola, Vraneš, Milan, "Interactions of caffeine and 1-butyl-3-methylimidazolium salicylate ionic liquid in water – Solubility, volumetric, acoustic, viscometric and refractometric studies supported by MD simulation" in Journal of Molecular Liquids, 397 (2024-03):124058,
https://doi.org/10.1016/j.molliq.2024.124058 . .

TY  - JOUR
AU  - Ivanović, Tijana
AU  - Popović, Daniela Ž.
AU  - Miladinović, Jelena
AU  - Miladinović, Zoran P.
AU  - Rajaković-Ognjanović, Vladana N.
AU  - Pastor, Ferenc
AU  - Mladenović, Anja
PY  - 2024-03
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7259
AB  - This study present estimation of the thermodynamic parameters and the influence of ionic activity coefficient on the thermodynamic equilibrium constant of adsorption of phosphates on fly ash. The adsorption was conducted over a wide range of initial phosphate concentrations at different pH values pH = (3; 7; 10). The adsorption results were treated using the Langmuir, Freundlich and Sips adsorption isotherms, which provide information about the maximum adsorption capacity. The Langmuir and Sips isotherms were a satisfactory fit to the adsorption data, especially at pH = 3, with an acceptable regression coefficient over the entire concentration range, Langmuir (r2 = 0.9737) and Sips (r2 = 0.9969). The estimated maximum phosphate sorption capacity of fly ash was 6.21 ± 0.68 (mmol·g−1) according to Langmuir and 4.19 ± 0.16 (mmol·g−1) according to the Sips model, at pH = 3.0. However, there is no data in the published literature for estimating the thermodynamic parameters of the phosphate adsorption process using thermodynamic models for activity coefficients. Novel approach of this paper was determination of the thermodynamic equilibrium constant and Gibbs free energy, using the Pitzer ion-interaction model to predict the nature of adsorption. The Pitzer-ion interaction model was used for the mixed ionic systems, taking into consideration the effect of other present ions besides phosphates in the equilibrium solution resulting from fly ash desorption. The procedure for comprehensive estimation of the ion activity coefficient at maximum adsorption capacity and the dimensionless thermodynamic equilibrium constant using Langmuir's and Sips's constants was presented. The calculated value of the phosphate activity coefficient in the equilibrium solution was γH = 0.7003 ± 0.0027 and the converted molar activity coefficient was γH = 0.6903 ± 0.0027. The estimated values of Gibbs free energy were: ΔGL = −6.788 ± 0.521 kJ·mol−1 based on Langmuir equilibrium constant and ΔGa = −7.707 ± 0.527 kJ·mol−1 based on activity and thermodynamic equilibrium constant. According to Sips model, the adsorption process is even more spontaneous, with the Gibbs free energy calculated using the phosphate activity coefficient and the thermodynamic equilibrium constant, ΔGa = −9.707 ± 0.617 kJ·mol−1. Consideration of the ionic activity coefficient is particularly important for large, charged adsorbates at higher concentrations, as the absolute difference in free energy for adsorption is app. 12 %. The scientific contribution is reflected in obtaining the necessary and more accurate information for the improvement of adsorption processes and possibly for the upgrading of fly ash in overall wastewater treatment technology.
PB  - Elsevier B.V.
T2  - Journal of Molecular Liquids
T1  - Advanced thermodynamic approach to adsorption of charged adsorbates from aqueous electrolyte solutions
SP  - 124097
VL  - 397
DO  - 10.1016/j.molliq.2024.124097
ER  - 

@article{
author = "Ivanović, Tijana and Popović, Daniela Ž. and Miladinović, Jelena and Miladinović, Zoran P. and Rajaković-Ognjanović, Vladana N. and Pastor, Ferenc and Mladenović, Anja",
year = "2024-03",
abstract = "This study present estimation of the thermodynamic parameters and the influence of ionic activity coefficient on the thermodynamic equilibrium constant of adsorption of phosphates on fly ash. The adsorption was conducted over a wide range of initial phosphate concentrations at different pH values pH = (3; 7; 10). The adsorption results were treated using the Langmuir, Freundlich and Sips adsorption isotherms, which provide information about the maximum adsorption capacity. The Langmuir and Sips isotherms were a satisfactory fit to the adsorption data, especially at pH = 3, with an acceptable regression coefficient over the entire concentration range, Langmuir (r2 = 0.9737) and Sips (r2 = 0.9969). The estimated maximum phosphate sorption capacity of fly ash was 6.21 ± 0.68 (mmol·g−1) according to Langmuir and 4.19 ± 0.16 (mmol·g−1) according to the Sips model, at pH = 3.0. However, there is no data in the published literature for estimating the thermodynamic parameters of the phosphate adsorption process using thermodynamic models for activity coefficients. Novel approach of this paper was determination of the thermodynamic equilibrium constant and Gibbs free energy, using the Pitzer ion-interaction model to predict the nature of adsorption. The Pitzer-ion interaction model was used for the mixed ionic systems, taking into consideration the effect of other present ions besides phosphates in the equilibrium solution resulting from fly ash desorption. The procedure for comprehensive estimation of the ion activity coefficient at maximum adsorption capacity and the dimensionless thermodynamic equilibrium constant using Langmuir's and Sips's constants was presented. The calculated value of the phosphate activity coefficient in the equilibrium solution was γH = 0.7003 ± 0.0027 and the converted molar activity coefficient was γH = 0.6903 ± 0.0027. The estimated values of Gibbs free energy were: ΔGL = −6.788 ± 0.521 kJ·mol−1 based on Langmuir equilibrium constant and ΔGa = −7.707 ± 0.527 kJ·mol−1 based on activity and thermodynamic equilibrium constant. According to Sips model, the adsorption process is even more spontaneous, with the Gibbs free energy calculated using the phosphate activity coefficient and the thermodynamic equilibrium constant, ΔGa = −9.707 ± 0.617 kJ·mol−1. Consideration of the ionic activity coefficient is particularly important for large, charged adsorbates at higher concentrations, as the absolute difference in free energy for adsorption is app. 12 %. The scientific contribution is reflected in obtaining the necessary and more accurate information for the improvement of adsorption processes and possibly for the upgrading of fly ash in overall wastewater treatment technology.",
publisher = "Elsevier B.V.",
journal = "Journal of Molecular Liquids",
title = "Advanced thermodynamic approach to adsorption of charged adsorbates from aqueous electrolyte solutions",
pages = "124097",
volume = "397",
doi = "10.1016/j.molliq.2024.124097"
}

Ivanović, T., Popović, D. Ž., Miladinović, J., Miladinović, Z. P., Rajaković-Ognjanović, V. N., Pastor, F.,& Mladenović, A.. (2024-03). Advanced thermodynamic approach to adsorption of charged adsorbates from aqueous electrolyte solutions. in Journal of Molecular Liquids
Elsevier B.V.., 397, 124097.
https://doi.org/10.1016/j.molliq.2024.124097

Ivanović T, Popović DŽ, Miladinović J, Miladinović ZP, Rajaković-Ognjanović VN, Pastor F, Mladenović A. Advanced thermodynamic approach to adsorption of charged adsorbates from aqueous electrolyte solutions. in Journal of Molecular Liquids. 2024;397:124097.
doi:10.1016/j.molliq.2024.124097 .

Ivanović, Tijana, Popović, Daniela Ž., Miladinović, Jelena, Miladinović, Zoran P., Rajaković-Ognjanović, Vladana N., Pastor, Ferenc, Mladenović, Anja, "Advanced thermodynamic approach to adsorption of charged adsorbates from aqueous electrolyte solutions" in Journal of Molecular Liquids, 397 (2024-03):124097,
https://doi.org/10.1016/j.molliq.2024.124097 . .

TY  - JOUR
AU  - Kosić, Višnja
AU  - Božić, Nataša
AU  - Dojnov, Biljana
AU  - Banković, Predrag
AU  - Jović-Jovičić, Nataša
AU  - Knežević-Jugović, Zorica
AU  - Milutinović-Nikolić, Aleksandra
PY  - 2024-03
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7279
AB  - Three glycoside hydrolases (α-amylase, xylanase and pullulanase) were immobilized on low-cost, environmentally friendly, easily modified clay rich in beidellite. Modifications included common procedures: Na-exchange, acid activation, pillaring, pillaring followed by acid activation, and organo-modifications with chitosan. Supports were characterized by chemical analysis, low temperature N2 physisorption, X-ray powder diffraction (XRPD) and Fourier-transform infrared (FT-IR) spectroscopy. The point of zero charge was also determined. Specific activity of different immobilizates of selected glycoside hydrolases was notably influenced by the type of chemical modification of supports. For each enzyme optimal support was chosen and storage stability was tested. α-Amylase immobilized on acid-activated support retained up to 95% of its initial specific activity of 105.6 ± 5.1 U g−1 after a testing period of 120 days. The most suitable support for xylanase was chitosan-modified beidellite with having specific activity of 90.0 ± 1.4 U g−1 which retained >50% its value after 120 days. Specific activity of pullulanase immobilized on pillared sample that was subsequently activated by acid was 44.5 ± 0.7 U g−1. Initial activity was preserved up to 33% for the same testing period. Comparing these results to the storage stability of the free enzymes that completely lost their activity for the longest period of 40 days, it can be concluded that appropriately modified beidellite- based clays could be used as suitable supports for stabilization of glycoside hydrolases. Nevertheless, further characterization of immobilizates (pH, thermal and operational stability) is needed in order to raise the suitability for larger scale processes in food industry.
PB  - Elsevier Ltd.
T2  - Applied Clay Science
T1  - Significantly improved stabilization of glycoside hydrolases important in food industry by immobilization onto appropriately modified beidellite
SP  - 107289
VL  - 250
DO  - 10.1016/j.clay.2024.107289
ER  - 

@article{
author = "Kosić, Višnja and Božić, Nataša and Dojnov, Biljana and Banković, Predrag and Jović-Jovičić, Nataša and Knežević-Jugović, Zorica and Milutinović-Nikolić, Aleksandra",
year = "2024-03",
abstract = "Three glycoside hydrolases (α-amylase, xylanase and pullulanase) were immobilized on low-cost, environmentally friendly, easily modified clay rich in beidellite. Modifications included common procedures: Na-exchange, acid activation, pillaring, pillaring followed by acid activation, and organo-modifications with chitosan. Supports were characterized by chemical analysis, low temperature N2 physisorption, X-ray powder diffraction (XRPD) and Fourier-transform infrared (FT-IR) spectroscopy. The point of zero charge was also determined. Specific activity of different immobilizates of selected glycoside hydrolases was notably influenced by the type of chemical modification of supports. For each enzyme optimal support was chosen and storage stability was tested. α-Amylase immobilized on acid-activated support retained up to 95% of its initial specific activity of 105.6 ± 5.1 U g−1 after a testing period of 120 days. The most suitable support for xylanase was chitosan-modified beidellite with having specific activity of 90.0 ± 1.4 U g−1 which retained >50% its value after 120 days. Specific activity of pullulanase immobilized on pillared sample that was subsequently activated by acid was 44.5 ± 0.7 U g−1. Initial activity was preserved up to 33% for the same testing period. Comparing these results to the storage stability of the free enzymes that completely lost their activity for the longest period of 40 days, it can be concluded that appropriately modified beidellite- based clays could be used as suitable supports for stabilization of glycoside hydrolases. Nevertheless, further characterization of immobilizates (pH, thermal and operational stability) is needed in order to raise the suitability for larger scale processes in food industry.",
publisher = "Elsevier Ltd.",
journal = "Applied Clay Science",
title = "Significantly improved stabilization of glycoside hydrolases important in food industry by immobilization onto appropriately modified beidellite",
pages = "107289",
volume = "250",
doi = "10.1016/j.clay.2024.107289"
}

Kosić, V., Božić, N., Dojnov, B., Banković, P., Jović-Jovičić, N., Knežević-Jugović, Z.,& Milutinović-Nikolić, A.. (2024-03). Significantly improved stabilization of glycoside hydrolases important in food industry by immobilization onto appropriately modified beidellite. in Applied Clay Science
Elsevier Ltd.., 250, 107289.
https://doi.org/10.1016/j.clay.2024.107289

Kosić V, Božić N, Dojnov B, Banković P, Jović-Jovičić N, Knežević-Jugović Z, Milutinović-Nikolić A. Significantly improved stabilization of glycoside hydrolases important in food industry by immobilization onto appropriately modified beidellite. in Applied Clay Science. 2024;250:107289.
doi:10.1016/j.clay.2024.107289 .

Kosić, Višnja, Božić, Nataša, Dojnov, Biljana, Banković, Predrag, Jović-Jovičić, Nataša, Knežević-Jugović, Zorica, Milutinović-Nikolić, Aleksandra, "Significantly improved stabilization of glycoside hydrolases important in food industry by immobilization onto appropriately modified beidellite" in Applied Clay Science, 250 (2024-03):107289,
https://doi.org/10.1016/j.clay.2024.107289 . .

TY  - JOUR
AU  - Pajić-Lijaković, Ivana
AU  - Milivojević, Milan
PY  - 2024-03
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7319
AB  - A crucial aspect of tissue self-organization during morphogenesis, wound healing, and cancer invasion is directed migration of cell collectives. The majority of in vivo directed migration has been guided by chemotaxis, whereby cells follow a chemical gradient. In certain situations, migrating cell collectives can also self-generate the stiffness gradient in the surrounding tissue, which can have a feedback effect on the directionality of the migration. The phenomenon has been observed during collective durotaxis in vivo. Along the biointerface between neighbouring tissues, heterotypic cell-cell interactions are the main cause of this self-generated stiffness gradient. The physical processes in charge of tissue self-organization along the biointerface, which are related to the interplay between cell signalling and the formation of heterotypic cell-cell adhesion contacts, are less well-developed than the biological mechanisms of the cellular interactions. This complex phenomenon is discussed here in the model system, such as collective migration of neural crest cells between ectodermal placode and mesoderm subpopulations within Xenopus embryos by pointing to the role of the dynamics along the biointerface between adjacent cell subpopulations on the subpopulation stiffness.
PB  - Elsevier B.V.
T2  - Biosystems
T1  - Collective durotaxis along a self-generated mobile stiffness gradient in vivo
SP  - 105155
VL  - 237
DO  - 10.1016/j.biosystems.2024.105155
ER  - 

@article{
author = "Pajić-Lijaković, Ivana and Milivojević, Milan",
year = "2024-03",
abstract = "A crucial aspect of tissue self-organization during morphogenesis, wound healing, and cancer invasion is directed migration of cell collectives. The majority of in vivo directed migration has been guided by chemotaxis, whereby cells follow a chemical gradient. In certain situations, migrating cell collectives can also self-generate the stiffness gradient in the surrounding tissue, which can have a feedback effect on the directionality of the migration. The phenomenon has been observed during collective durotaxis in vivo. Along the biointerface between neighbouring tissues, heterotypic cell-cell interactions are the main cause of this self-generated stiffness gradient. The physical processes in charge of tissue self-organization along the biointerface, which are related to the interplay between cell signalling and the formation of heterotypic cell-cell adhesion contacts, are less well-developed than the biological mechanisms of the cellular interactions. This complex phenomenon is discussed here in the model system, such as collective migration of neural crest cells between ectodermal placode and mesoderm subpopulations within Xenopus embryos by pointing to the role of the dynamics along the biointerface between adjacent cell subpopulations on the subpopulation stiffness.",
publisher = "Elsevier B.V.",
journal = "Biosystems",
title = "Collective durotaxis along a self-generated mobile stiffness gradient in vivo",
pages = "105155",
volume = "237",
doi = "10.1016/j.biosystems.2024.105155"
}

Pajić-Lijaković, I.,& Milivojević, M.. (2024-03). Collective durotaxis along a self-generated mobile stiffness gradient in vivo. in Biosystems
Elsevier B.V.., 237, 105155.
https://doi.org/10.1016/j.biosystems.2024.105155

Pajić-Lijaković I, Milivojević M. Collective durotaxis along a self-generated mobile stiffness gradient in vivo. in Biosystems. 2024;237:105155.
doi:10.1016/j.biosystems.2024.105155 .

Pajić-Lijaković, Ivana, Milivojević, Milan, "Collective durotaxis along a self-generated mobile stiffness gradient in vivo" in Biosystems, 237 (2024-03):105155,
https://doi.org/10.1016/j.biosystems.2024.105155 . .

TY  - JOUR
AU  - Anojčić, Jasmina
AU  - Mijin, Dušan
AU  - Eraković Pantović, Sanja
AU  - Bogdanović, Aleksandra
AU  - Turuntaš, Nikola
AU  - Mutić, Sanja
AU  - Petrović, Slobodan
AU  - Avramov Ivić, Milka
PY  - 2024-03
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7278
AB  - The anticholinergic drug, solifenacin, is frequently used for the treatment of the urological tract for urinary incontinence, and urinary frequency. The development of reliable and effective solifenacin electrochemical sensors is of great importance for the pharmaceutical industry and clinical practice. In this work, the electrochemical behavior of solifenacin succinate (SOL) was studied using three different working electrodes: gold (Au), glassy carbon (GCE) and boron-doped diamond electrode (BDDE). The cyclic voltammetric (CV) measurements performed in 0.05 M NaHCO3 indicated that the SOL oxidation process is irreversible and diffusion-controlled at all investigated working electrodes. Afterwards, the testing of SOL electrochemical stability and the possibility of its electrochemical degradation was performed at the Au electrode by the cycling of the potential during 3 h and continuously to 6 h. It was shown that the SOL was electrochemically transformed into another electroactive species and its degradation was excluded. For electroanalytical application, the anodically pretreated BDDE (+2.0 V; 30 s) was selected. Various experimental parameters were optimized, including the pH of the aqueous Britton-Robinson (B-R) buffer as a supporting electrolyte (from pH 2.0 to 11.98) and the most intensive peak of the target analyte was at pH 11.0, so this pH value was chosen as the optimum for further measurements. Based on the correlation of the SOL peak intensity and different concentrations, the developed differential pulse voltammetric (DPV) method was characterized by a linear concentration range from 0.041 to 2.50 µM, with a correlation coefficient of 0.999, and a relative standard deviation of 0.3 %. Taking into account the sensitivity of the developed DPV method towards the electrochemical oxidation of SOL, a very low detection limit of 0.012 µM in the model system was achieved. The BDDE showed adequate selectivity for SOL in the presence of the investigated interferents. The obtained results indicate that the BDDE with an optimized DPV method could be applied for the trace-level electroanalytical determination of SOL in human urine sample with excellent recovery and reproducibility.
PB  - Elsevier B.V.
T2  - Journal of Electroanalytical Chemistry
T1  - Voltammetric behavior of solifenacin succinate on gold, glassy carbon and boron-doped diamond electrodes: Stability testing and determination
SP  - 118113
VL  - 957
DO  - 10.1016/j.jelechem.2024.118113
ER  - 

@article{
author = "Anojčić, Jasmina and Mijin, Dušan and Eraković Pantović, Sanja and Bogdanović, Aleksandra and Turuntaš, Nikola and Mutić, Sanja and Petrović, Slobodan and Avramov Ivić, Milka",
year = "2024-03",
abstract = "The anticholinergic drug, solifenacin, is frequently used for the treatment of the urological tract for urinary incontinence, and urinary frequency. The development of reliable and effective solifenacin electrochemical sensors is of great importance for the pharmaceutical industry and clinical practice. In this work, the electrochemical behavior of solifenacin succinate (SOL) was studied using three different working electrodes: gold (Au), glassy carbon (GCE) and boron-doped diamond electrode (BDDE). The cyclic voltammetric (CV) measurements performed in 0.05 M NaHCO3 indicated that the SOL oxidation process is irreversible and diffusion-controlled at all investigated working electrodes. Afterwards, the testing of SOL electrochemical stability and the possibility of its electrochemical degradation was performed at the Au electrode by the cycling of the potential during 3 h and continuously to 6 h. It was shown that the SOL was electrochemically transformed into another electroactive species and its degradation was excluded. For electroanalytical application, the anodically pretreated BDDE (+2.0 V; 30 s) was selected. Various experimental parameters were optimized, including the pH of the aqueous Britton-Robinson (B-R) buffer as a supporting electrolyte (from pH 2.0 to 11.98) and the most intensive peak of the target analyte was at pH 11.0, so this pH value was chosen as the optimum for further measurements. Based on the correlation of the SOL peak intensity and different concentrations, the developed differential pulse voltammetric (DPV) method was characterized by a linear concentration range from 0.041 to 2.50 µM, with a correlation coefficient of 0.999, and a relative standard deviation of 0.3 %. Taking into account the sensitivity of the developed DPV method towards the electrochemical oxidation of SOL, a very low detection limit of 0.012 µM in the model system was achieved. The BDDE showed adequate selectivity for SOL in the presence of the investigated interferents. The obtained results indicate that the BDDE with an optimized DPV method could be applied for the trace-level electroanalytical determination of SOL in human urine sample with excellent recovery and reproducibility.",
publisher = "Elsevier B.V.",
journal = "Journal of Electroanalytical Chemistry",
title = "Voltammetric behavior of solifenacin succinate on gold, glassy carbon and boron-doped diamond electrodes: Stability testing and determination",
pages = "118113",
volume = "957",
doi = "10.1016/j.jelechem.2024.118113"
}

Anojčić, J., Mijin, D., Eraković Pantović, S., Bogdanović, A., Turuntaš, N., Mutić, S., Petrović, S.,& Avramov Ivić, M.. (2024-03). Voltammetric behavior of solifenacin succinate on gold, glassy carbon and boron-doped diamond electrodes: Stability testing and determination. in Journal of Electroanalytical Chemistry
Elsevier B.V.., 957, 118113.
https://doi.org/10.1016/j.jelechem.2024.118113

Anojčić J, Mijin D, Eraković Pantović S, Bogdanović A, Turuntaš N, Mutić S, Petrović S, Avramov Ivić M. Voltammetric behavior of solifenacin succinate on gold, glassy carbon and boron-doped diamond electrodes: Stability testing and determination. in Journal of Electroanalytical Chemistry. 2024;957:118113.
doi:10.1016/j.jelechem.2024.118113 .

Anojčić, Jasmina, Mijin, Dušan, Eraković Pantović, Sanja, Bogdanović, Aleksandra, Turuntaš, Nikola, Mutić, Sanja, Petrović, Slobodan, Avramov Ivić, Milka, "Voltammetric behavior of solifenacin succinate on gold, glassy carbon and boron-doped diamond electrodes: Stability testing and determination" in Journal of Electroanalytical Chemistry, 957 (2024-03):118113,
https://doi.org/10.1016/j.jelechem.2024.118113 . .

TY  - JOUR
AU  - Dimitrijević, Snežana
AU  - Milić, Marija
AU  - Tadić, Vanja
AU  - Maksimović, Svetolik
AU  - Filipović, Vladimir
AU  - Dimitrijević-Branković, Suzana
AU  - Miljković, Miona
AU  - Salamon, Ivan
PY  - 2024-02
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7036
AB  - Within this investigation, the effect of conventional and sophisticated extraction method was evaluated on the chemical composition of black cumin seeds (Nigella sativa L.) essential oils and their bioactive characteristics. Soxhlet extraction at 60 °C by hexane (SEH) and petroleum ether (SEP) was adopted as traditionally used technique, while the supercritical extraction with CO2 (SFE), under the pressure of 10 MPa and temperature of 40 °C, was performed as a modern method, expected to overcome the drawbacks of the conventional solvent extraction. The results showed that SFE enabled up to ten times higher extraction yields, compared to essential oils derived after Soxhlet extraction, however, the bioactive compounds content, such as polyphenols, flavonoids and carotenoids, were extracted in higher quantities in the oil from Soxhlet extraction performance. Thereby, the strongest antioxidant agent was found to be the essential oil obtained from SEP, followed by the oil from SFE and oil obtained from SEH, respectively. The GC-MS analysis revealed that the content of thymoquinone was the highest in the essential oil from SEP (69.58%), and the obtained values are among the highest reported within the available literature data. Also, this oil sample contained about eleven times higher thymoquinone quantities than the essential oil obtained by SFE, which was mostly constituted of a methyl linoleate, a fatty acid methyl ester of linoleic acid. In addition, the essential oil from SEP exerted a value added antimicrobial properties, where it was found to be particularly effective in suppression of the Gram-positive bacteria growth.
PB  - Elsevier B.V.
T2  - Sustainable Chemistry and Pharmacy
T1  - Black cumin essential oil as a valuable source of bioactive compounds: Evaluation of the conventional vs. modern extraction technique
SP  - 101390
VL  - 37
DO  - 10.1016/j.scp.2023.101390
ER  - 

@article{
author = "Dimitrijević, Snežana and Milić, Marija and Tadić, Vanja and Maksimović, Svetolik and Filipović, Vladimir and Dimitrijević-Branković, Suzana and Miljković, Miona and Salamon, Ivan",
year = "2024-02",
abstract = "Within this investigation, the effect of conventional and sophisticated extraction method was evaluated on the chemical composition of black cumin seeds (Nigella sativa L.) essential oils and their bioactive characteristics. Soxhlet extraction at 60 °C by hexane (SEH) and petroleum ether (SEP) was adopted as traditionally used technique, while the supercritical extraction with CO2 (SFE), under the pressure of 10 MPa and temperature of 40 °C, was performed as a modern method, expected to overcome the drawbacks of the conventional solvent extraction. The results showed that SFE enabled up to ten times higher extraction yields, compared to essential oils derived after Soxhlet extraction, however, the bioactive compounds content, such as polyphenols, flavonoids and carotenoids, were extracted in higher quantities in the oil from Soxhlet extraction performance. Thereby, the strongest antioxidant agent was found to be the essential oil obtained from SEP, followed by the oil from SFE and oil obtained from SEH, respectively. The GC-MS analysis revealed that the content of thymoquinone was the highest in the essential oil from SEP (69.58%), and the obtained values are among the highest reported within the available literature data. Also, this oil sample contained about eleven times higher thymoquinone quantities than the essential oil obtained by SFE, which was mostly constituted of a methyl linoleate, a fatty acid methyl ester of linoleic acid. In addition, the essential oil from SEP exerted a value added antimicrobial properties, where it was found to be particularly effective in suppression of the Gram-positive bacteria growth.",
publisher = "Elsevier B.V.",
journal = "Sustainable Chemistry and Pharmacy",
title = "Black cumin essential oil as a valuable source of bioactive compounds: Evaluation of the conventional vs. modern extraction technique",
pages = "101390",
volume = "37",
doi = "10.1016/j.scp.2023.101390"
}

Dimitrijević, S., Milić, M., Tadić, V., Maksimović, S., Filipović, V., Dimitrijević-Branković, S., Miljković, M.,& Salamon, I.. (2024-02). Black cumin essential oil as a valuable source of bioactive compounds: Evaluation of the conventional vs. modern extraction technique. in Sustainable Chemistry and Pharmacy
Elsevier B.V.., 37, 101390.
https://doi.org/10.1016/j.scp.2023.101390

Dimitrijević S, Milić M, Tadić V, Maksimović S, Filipović V, Dimitrijević-Branković S, Miljković M, Salamon I. Black cumin essential oil as a valuable source of bioactive compounds: Evaluation of the conventional vs. modern extraction technique. in Sustainable Chemistry and Pharmacy. 2024;37:101390.
doi:10.1016/j.scp.2023.101390 .

Dimitrijević, Snežana, Milić, Marija, Tadić, Vanja, Maksimović, Svetolik, Filipović, Vladimir, Dimitrijević-Branković, Suzana, Miljković, Miona, Salamon, Ivan, "Black cumin essential oil as a valuable source of bioactive compounds: Evaluation of the conventional vs. modern extraction technique" in Sustainable Chemistry and Pharmacy, 37 (2024-02):101390,
https://doi.org/10.1016/j.scp.2023.101390 . .

TY  - JOUR
AU  - Mandura Jarić, Ana
AU  - Haramustek, Laura
AU  - Nižić Nodilo, Laura
AU  - Vrsaljko, Domagoj
AU  - Petrović, Predrag
AU  - Kuzmić, Sunčica
AU  - Jozinović, Antun
AU  - Aladić, Krunoslav
AU  - Jokić, Stela
AU  - Šeremet, Danijela
AU  - Vojvodić Cebin, Aleksandra
AU  - Komes, Draženka
PY  - 2024-02
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7280
AB  - In this study, spray drying was used as a technological solution for the valorization of Teucrium montanum extract into carboxymethyl cellulose-based delivery systems (CMC), individually or in combination with collagen, guar gum, gum arabic, and kappa-carrageenan. The results showed that the process yield and morphological properties were positively influenced by the introduction of CMC binary blends. The employment of CMC resulted in a high encapsulation efficiency (77–96%) for all phenylethanoid glycosides (PGs) analyzed. Due to the low wettability of the microparticles, a relatively gradual in vitro release of the PGs was achieved. Infusion of the filling with hydrophilic T. montanum extract encapsulated in microparticles with high hydrophobic surface area proved to be a practical route for significant confectionery fortification (5–9 mg PGs per dw serving), ensuring prolonged interaction between the food matrix used and the extract under simulated gastrointestinal conditions. Based on sensory evaluation, the introduction of kudzu starch into the jelly matrix has shown a texture-modifying potential.
PB  - MDPI
T2  - Foods
T1  - A Novel Approach to Serving Plant-Based Confectionery—The Employment of Spray Drying in the Production of Carboxymethyl Cellulose-Based Delivery Systems Enriched with Teucrium montanum L. Extract
IS  - 3
SP  - 372
VL  - 13
DO  - 10.3390/foods13030372
ER  - 

@article{
author = "Mandura Jarić, Ana and Haramustek, Laura and Nižić Nodilo, Laura and Vrsaljko, Domagoj and Petrović, Predrag and Kuzmić, Sunčica and Jozinović, Antun and Aladić, Krunoslav and Jokić, Stela and Šeremet, Danijela and Vojvodić Cebin, Aleksandra and Komes, Draženka",
year = "2024-02",
abstract = "In this study, spray drying was used as a technological solution for the valorization of Teucrium montanum extract into carboxymethyl cellulose-based delivery systems (CMC), individually or in combination with collagen, guar gum, gum arabic, and kappa-carrageenan. The results showed that the process yield and morphological properties were positively influenced by the introduction of CMC binary blends. The employment of CMC resulted in a high encapsulation efficiency (77–96%) for all phenylethanoid glycosides (PGs) analyzed. Due to the low wettability of the microparticles, a relatively gradual in vitro release of the PGs was achieved. Infusion of the filling with hydrophilic T. montanum extract encapsulated in microparticles with high hydrophobic surface area proved to be a practical route for significant confectionery fortification (5–9 mg PGs per dw serving), ensuring prolonged interaction between the food matrix used and the extract under simulated gastrointestinal conditions. Based on sensory evaluation, the introduction of kudzu starch into the jelly matrix has shown a texture-modifying potential.",
publisher = "MDPI",
journal = "Foods",
title = "A Novel Approach to Serving Plant-Based Confectionery—The Employment of Spray Drying in the Production of Carboxymethyl Cellulose-Based Delivery Systems Enriched with Teucrium montanum L. Extract",
number = "3",
pages = "372",
volume = "13",
doi = "10.3390/foods13030372"
}

Mandura Jarić, A., Haramustek, L., Nižić Nodilo, L., Vrsaljko, D., Petrović, P., Kuzmić, S., Jozinović, A., Aladić, K., Jokić, S., Šeremet, D., Vojvodić Cebin, A.,& Komes, D.. (2024-02). A Novel Approach to Serving Plant-Based Confectionery—The Employment of Spray Drying in the Production of Carboxymethyl Cellulose-Based Delivery Systems Enriched with Teucrium montanum L. Extract. in Foods
MDPI., 13(3), 372.
https://doi.org/10.3390/foods13030372

Mandura Jarić A, Haramustek L, Nižić Nodilo L, Vrsaljko D, Petrović P, Kuzmić S, Jozinović A, Aladić K, Jokić S, Šeremet D, Vojvodić Cebin A, Komes D. A Novel Approach to Serving Plant-Based Confectionery—The Employment of Spray Drying in the Production of Carboxymethyl Cellulose-Based Delivery Systems Enriched with Teucrium montanum L. Extract. in Foods. 2024;13(3):372.
doi:10.3390/foods13030372 .

Mandura Jarić, Ana, Haramustek, Laura, Nižić Nodilo, Laura, Vrsaljko, Domagoj, Petrović, Predrag, Kuzmić, Sunčica, Jozinović, Antun, Aladić, Krunoslav, Jokić, Stela, Šeremet, Danijela, Vojvodić Cebin, Aleksandra, Komes, Draženka, "A Novel Approach to Serving Plant-Based Confectionery—The Employment of Spray Drying in the Production of Carboxymethyl Cellulose-Based Delivery Systems Enriched with Teucrium montanum L. Extract" in Foods, 13, no. 3 (2024-02):372,
https://doi.org/10.3390/foods13030372 . .

TY  - JOUR
AU  - Kutyła, Dawid
AU  - Krstajić Pajić, Mila N.
AU  - Lačnjevac, Uroš Č.
AU  - Marzec, Mateusz M.
AU  - Elezović, Nevenka R.
AU  - Żabiński, Piotr
PY  - 2024-02
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6992
AB  - This study investigates the structure, electrochemical behavior and hydrogen evolution reaction (HER) performance of electrodeposited Ru–Co alloy coatings. The alloys were prepared from a 0.75 M Co2+ + 0.025 M Ru3+ solution at various potentials ranging from −0.5 to −1.2 V vs. SCE. Results reveal that the Ru and Co deposition processes are interdependent. The deposition of nobler Ru from the mixed metal solution reaches pure diffusion control already at −0.7 V compared to −1.0 V from a single Ru bath. On the other hand, Co deposition is significantly facilitated in the presence of Ru in the solution. Consequently, as the deposition potential changes from −0.6 to −1.0 V, Ru–Co solid solution coatings characterized by a distinct globular morphology are formed, with their Co content increasing from 22.1/7.4 to 70.2/86.1 wt% for the Cu/Ti2AlC MAX phase substrate applied. The alloy catalysts are found to show much better HER activity and stability in alkaline than in acidic solutions. The best Ru–Co@Ti2AlC sample, electrodeposited at −0.6 V, requires an overpotential of only −95 mV to deliver a current density of −100 mA cm−2 in 1 M KOH, thus outperforming most Ru–Co-based HER electrocatalysts reported to date.
PB  - Elsevier Ltd.
T2  - International Journal of Hydrogen Energy
T1  - Ru–Co alloy coatings electrodeposited on a MAX phase substrate as efficient catalysts for the hydrogen evolution reaction
EP  - 40
SP  - 28
VL  - 56
DO  - 10.1016/j.ijhydene.2023.11.296
ER  - 

@article{
author = "Kutyła, Dawid and Krstajić Pajić, Mila N. and Lačnjevac, Uroš Č. and Marzec, Mateusz M. and Elezović, Nevenka R. and Żabiński, Piotr",
year = "2024-02",
abstract = "This study investigates the structure, electrochemical behavior and hydrogen evolution reaction (HER) performance of electrodeposited Ru–Co alloy coatings. The alloys were prepared from a 0.75 M Co2+ + 0.025 M Ru3+ solution at various potentials ranging from −0.5 to −1.2 V vs. SCE. Results reveal that the Ru and Co deposition processes are interdependent. The deposition of nobler Ru from the mixed metal solution reaches pure diffusion control already at −0.7 V compared to −1.0 V from a single Ru bath. On the other hand, Co deposition is significantly facilitated in the presence of Ru in the solution. Consequently, as the deposition potential changes from −0.6 to −1.0 V, Ru–Co solid solution coatings characterized by a distinct globular morphology are formed, with their Co content increasing from 22.1/7.4 to 70.2/86.1 wt% for the Cu/Ti2AlC MAX phase substrate applied. The alloy catalysts are found to show much better HER activity and stability in alkaline than in acidic solutions. The best Ru–Co@Ti2AlC sample, electrodeposited at −0.6 V, requires an overpotential of only −95 mV to deliver a current density of −100 mA cm−2 in 1 M KOH, thus outperforming most Ru–Co-based HER electrocatalysts reported to date.",
publisher = "Elsevier Ltd.",
journal = "International Journal of Hydrogen Energy",
title = "Ru–Co alloy coatings electrodeposited on a MAX phase substrate as efficient catalysts for the hydrogen evolution reaction",
pages = "40-28",
volume = "56",
doi = "10.1016/j.ijhydene.2023.11.296"
}

Kutyła, D., Krstajić Pajić, M. N., Lačnjevac, U. Č., Marzec, M. M., Elezović, N. R.,& Żabiński, P.. (2024-02). Ru–Co alloy coatings electrodeposited on a MAX phase substrate as efficient catalysts for the hydrogen evolution reaction. in International Journal of Hydrogen Energy
Elsevier Ltd.., 56, 28-40.
https://doi.org/10.1016/j.ijhydene.2023.11.296

Kutyła D, Krstajić Pajić MN, Lačnjevac UČ, Marzec MM, Elezović NR, Żabiński P. Ru–Co alloy coatings electrodeposited on a MAX phase substrate as efficient catalysts for the hydrogen evolution reaction. in International Journal of Hydrogen Energy. 2024;56:28-40.
doi:10.1016/j.ijhydene.2023.11.296 .

Kutyła, Dawid, Krstajić Pajić, Mila N., Lačnjevac, Uroš Č., Marzec, Mateusz M., Elezović, Nevenka R., Żabiński, Piotr, "Ru–Co alloy coatings electrodeposited on a MAX phase substrate as efficient catalysts for the hydrogen evolution reaction" in International Journal of Hydrogen Energy, 56 (2024-02):28-40,
https://doi.org/10.1016/j.ijhydene.2023.11.296 . .

TY  - JOUR
AU  - Zhang, Houcheng
AU  - Li, Jiarui
AU  - Xue, Yejian
AU  - Grgur, Branimir N.
AU  - Li, Jianming
PY  - 2024-02
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7035
AB  - Tubular solid oxide fuel cells (TSOFCs) are a promising technology for electricity generation; however, they also generate high-temperature waste heat, leading to reduced efficiency and energy wastage. To address this challenge and unlock the full potential, a novel geometry-matching hybrid system incorporating methane reforming TSOFC and hydrophilic modified tubular still (HMTS) is proposed and modelled. Considering various irreversible losses, vital performance indicators including power output, energy efficiency and exergy efficiency are firstly derived, through which comprehensive thermodynamic performance features of the TSOFC/HMTS hybrid system are predicted. The proposed system design demonstrates a significant advantage by achieving a maximum output power density that is 99.7 % higher and a corresponding energy efficiency that is 57.3 % higher compared to the standalone TSOFC. Extensive parametric analyses reveal that raising the operating temperature or stream/carbon ratio positively enhances the system's performance. Conversely, increasing electrode tortuosity, electrolyte thickness, wind velocity, or tubular shell diameter negatively degrades the system's performance. In addition, the anode thickness is an optimizable parameter. Local sensitivity analyses identify that the operation temperature and electrode tortuosity are, respectively, the most and least sensitive parameters for performance regulation. The findings make a significant step forward in the field of sustainable and innovative energy solutions.
PB  - Elsevier Ltd.
T2  - Energy
T1  - Performance prediction and regulation of a tubular solid oxide fuel cell and hydrophilic modified tubular still hybrid system for electricity and freshwater cogeneration
SP  - 129893
VL  - 289
DO  - 10.1016/j.energy.2023.129893
ER  - 

@article{
author = "Zhang, Houcheng and Li, Jiarui and Xue, Yejian and Grgur, Branimir N. and Li, Jianming",
year = "2024-02",
abstract = "Tubular solid oxide fuel cells (TSOFCs) are a promising technology for electricity generation; however, they also generate high-temperature waste heat, leading to reduced efficiency and energy wastage. To address this challenge and unlock the full potential, a novel geometry-matching hybrid system incorporating methane reforming TSOFC and hydrophilic modified tubular still (HMTS) is proposed and modelled. Considering various irreversible losses, vital performance indicators including power output, energy efficiency and exergy efficiency are firstly derived, through which comprehensive thermodynamic performance features of the TSOFC/HMTS hybrid system are predicted. The proposed system design demonstrates a significant advantage by achieving a maximum output power density that is 99.7 % higher and a corresponding energy efficiency that is 57.3 % higher compared to the standalone TSOFC. Extensive parametric analyses reveal that raising the operating temperature or stream/carbon ratio positively enhances the system's performance. Conversely, increasing electrode tortuosity, electrolyte thickness, wind velocity, or tubular shell diameter negatively degrades the system's performance. In addition, the anode thickness is an optimizable parameter. Local sensitivity analyses identify that the operation temperature and electrode tortuosity are, respectively, the most and least sensitive parameters for performance regulation. The findings make a significant step forward in the field of sustainable and innovative energy solutions.",
publisher = "Elsevier Ltd.",
journal = "Energy",
title = "Performance prediction and regulation of a tubular solid oxide fuel cell and hydrophilic modified tubular still hybrid system for electricity and freshwater cogeneration",
pages = "129893",
volume = "289",
doi = "10.1016/j.energy.2023.129893"
}

Zhang, H., Li, J., Xue, Y., Grgur, B. N.,& Li, J.. (2024-02). Performance prediction and regulation of a tubular solid oxide fuel cell and hydrophilic modified tubular still hybrid system for electricity and freshwater cogeneration. in Energy
Elsevier Ltd.., 289, 129893.
https://doi.org/10.1016/j.energy.2023.129893

Zhang H, Li J, Xue Y, Grgur BN, Li J. Performance prediction and regulation of a tubular solid oxide fuel cell and hydrophilic modified tubular still hybrid system for electricity and freshwater cogeneration. in Energy. 2024;289:129893.
doi:10.1016/j.energy.2023.129893 .

Zhang, Houcheng, Li, Jiarui, Xue, Yejian, Grgur, Branimir N., Li, Jianming, "Performance prediction and regulation of a tubular solid oxide fuel cell and hydrophilic modified tubular still hybrid system for electricity and freshwater cogeneration" in Energy, 289 (2024-02):129893,
https://doi.org/10.1016/j.energy.2023.129893 . .

TY  - JOUR
AU  - Stefanović, Ivan S.
AU  - Džunuzović, Jasna V.
AU  - Džunuzović, Enis S.
AU  - Ranđelović, Danijela V.
PY  - 2024-02
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6993
AB  - The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.
PB  - John Wiley and Sons Inc.
T2  - Journal of Applied Polymer Science
T1  - The influence of polycaprolactone content on the surface properties of polyurethane networks
IS  - 8
SP  - e54989
VL  - 141
DO  - 10.1002/app.54989
ER  - 

@article{
author = "Stefanović, Ivan S. and Džunuzović, Jasna V. and Džunuzović, Enis S. and Ranđelović, Danijela V.",
year = "2024-02",
abstract = "The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.",
publisher = "John Wiley and Sons Inc.",
journal = "Journal of Applied Polymer Science",
title = "The influence of polycaprolactone content on the surface properties of polyurethane networks",
number = "8",
pages = "e54989",
volume = "141",
doi = "10.1002/app.54989"
}

Stefanović, I. S., Džunuzović, J. V., Džunuzović, E. S.,& Ranđelović, D. V.. (2024-02). The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science
John Wiley and Sons Inc.., 141(8), e54989.
https://doi.org/10.1002/app.54989

Stefanović IS, Džunuzović JV, Džunuzović ES, Ranđelović DV. The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science. 2024;141(8):e54989.
doi:10.1002/app.54989 .

Stefanović, Ivan S., Džunuzović, Jasna V., Džunuzović, Enis S., Ranđelović, Danijela V., "The influence of polycaprolactone content on the surface properties of polyurethane networks" in Journal of Applied Polymer Science, 141, no. 8 (2024-02):e54989,
https://doi.org/10.1002/app.54989 . .

TY  - JOUR
AU  - Petkovska, Jovana
AU  - Geskovski, Nikola
AU  - Marković, Darka
AU  - Dimova, Vesna
AU  - Mirakovski, Dejan
AU  - Radetić, Maja
AU  - Jordanov, Igor
PY  - 2024-01
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7155
AB  - Environmentally benign pH-indicating wound dressing comprised of carbohydrates chitosan (CH) and pectin (P), and anthocyanin grape (AG) dye is created via layer-by-layer assembly. Cotton fabric coated with eight bilayers of (CH-AG)4/(P-AG)4 deposited 1.97 % AG-dye. It exhibited a visible and immediate color change from pink to violet-blue while increasing its pH value from 6 to pH 7, matching the turning pH point of healing into an infected wound. Color transition of AG-dye in water-based buffers, tested by VIS-spectroscopy, shows the same color change when the pH value increased from 6 to 7. This coating imparts excellent antimicrobial activity against Gram-positive bacteria Staphylococcus aureus and yeast Candida albicans, moderate antibacterial activity against Gram-negative Escherichia coli bacteria, and no cytotoxicity on human fibroblast cells (MRC-5). This research proposes a sustainable, low-cost, and simple method for obtaining smart wound dressing that provides real-time monitoring of the wound pH.
PB  - Elsevier Ltd.
T2  - Carbohydrate Polymer Technologies and Applications
T1  - Chitosan-pectin multilayer coating with anthocyanin grape dye as pH indicating wound dressing: Synthesis and characterization
SP  - 100438
VL  - 7
DO  - 10.1016/j.carpta.2024.100438
ER  - 

@article{
author = "Petkovska, Jovana and Geskovski, Nikola and Marković, Darka and Dimova, Vesna and Mirakovski, Dejan and Radetić, Maja and Jordanov, Igor",
year = "2024-01",
abstract = "Environmentally benign pH-indicating wound dressing comprised of carbohydrates chitosan (CH) and pectin (P), and anthocyanin grape (AG) dye is created via layer-by-layer assembly. Cotton fabric coated with eight bilayers of (CH-AG)4/(P-AG)4 deposited 1.97 % AG-dye. It exhibited a visible and immediate color change from pink to violet-blue while increasing its pH value from 6 to pH 7, matching the turning pH point of healing into an infected wound. Color transition of AG-dye in water-based buffers, tested by VIS-spectroscopy, shows the same color change when the pH value increased from 6 to 7. This coating imparts excellent antimicrobial activity against Gram-positive bacteria Staphylococcus aureus and yeast Candida albicans, moderate antibacterial activity against Gram-negative Escherichia coli bacteria, and no cytotoxicity on human fibroblast cells (MRC-5). This research proposes a sustainable, low-cost, and simple method for obtaining smart wound dressing that provides real-time monitoring of the wound pH.",
publisher = "Elsevier Ltd.",
journal = "Carbohydrate Polymer Technologies and Applications",
title = "Chitosan-pectin multilayer coating with anthocyanin grape dye as pH indicating wound dressing: Synthesis and characterization",
pages = "100438",
volume = "7",
doi = "10.1016/j.carpta.2024.100438"
}

Petkovska, J., Geskovski, N., Marković, D., Dimova, V., Mirakovski, D., Radetić, M.,& Jordanov, I.. (2024-01). Chitosan-pectin multilayer coating with anthocyanin grape dye as pH indicating wound dressing: Synthesis and characterization. in Carbohydrate Polymer Technologies and Applications
Elsevier Ltd.., 7, 100438.
https://doi.org/10.1016/j.carpta.2024.100438

Petkovska J, Geskovski N, Marković D, Dimova V, Mirakovski D, Radetić M, Jordanov I. Chitosan-pectin multilayer coating with anthocyanin grape dye as pH indicating wound dressing: Synthesis and characterization. in Carbohydrate Polymer Technologies and Applications. 2024;7:100438.
doi:10.1016/j.carpta.2024.100438 .

Petkovska, Jovana, Geskovski, Nikola, Marković, Darka, Dimova, Vesna, Mirakovski, Dejan, Radetić, Maja, Jordanov, Igor, "Chitosan-pectin multilayer coating with anthocyanin grape dye as pH indicating wound dressing: Synthesis and characterization" in Carbohydrate Polymer Technologies and Applications, 7 (2024-01):100438,
https://doi.org/10.1016/j.carpta.2024.100438 . .

TY  - JOUR
AU  - Kasalović, Marijana P.
AU  - Jelača, Sanja
AU  - Maksimović-Ivanić, Danijela
AU  - Lađarević, Jelena
AU  - Radovanović, Lidija
AU  - Božić, Bojan
AU  - Mijatović, Sanja
AU  - Pantelić, Nebojša Đ.
AU  - Kaluđerović, Goran N.
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6760
AB  - Three new diphenyltin(IV) complexes, bis(3-(4-methyl-2-oxoquinolinyl-1(2H)-yl)propanoato)diphenyltin(IV)
(1), bis(2-(4-methyl-2-oxoquinolin-1(2H)-yl)ethanoato)diphenyltin(IV) (2), and bis(2-(4-hydroxy-2-oxoquinolin1(2H)-yl)ethanoato)diphenyltin(IV) (3), were synthesized and characterized by elemental microanalysis, FT-IR
spectroscopy, and multinuclear (
1
H, 13C and 119Sn) NMR spectroscopy. Crystal structure of ligand precursor,
2-(4-methyl-2-oxoquinolinyl-1-(2H)-yl)acetic acid (HL2), has been determined by X-ray diffraction studies.
Asymmetric bidentate coordination of the carboxylato ligands and skew trapezoidal structures are assumed for
the synthesized complexes. In vitro anticancer activity of the synthesized diphenyltin(IV) complexes was evaluated against three human: MCF-7 (breast adenocarcinoma), A375 (melanoma), HCT116 (colorectal carcinoma),
and three mouse tumor cell lines: 4T1 (breast carcinoma), B16 (melanoma), CT26 (colon carcinoma) using MTT
and CV assays. The IC50 values fall in the range from 0.1 to 3.7 μM. Flow cytometric analysis and fluorescent
microscopy suggest that complex 1 induces caspase-dependent apoptosis followed with strong blockade of cell
division in HCT116 cells. Since complex 1 showed ROS/RNS scavenging potential mentioned cytotoxicity was
not connected with oxidative stress.
PB  - Elsevier Inc.
T2  - Journal of Inorganic Biochemistry
T1  - Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies
SP  - 112399
VL  - 250
DO  - 10.1016/j.jinorgbio.2023.112399
ER  - 

@article{
author = "Kasalović, Marijana P. and Jelača, Sanja and Maksimović-Ivanić, Danijela and Lađarević, Jelena and Radovanović, Lidija and Božić, Bojan and Mijatović, Sanja and Pantelić, Nebojša Đ. and Kaluđerović, Goran N.",
year = "2024",
abstract = "Three new diphenyltin(IV) complexes, bis(3-(4-methyl-2-oxoquinolinyl-1(2H)-yl)propanoato)diphenyltin(IV)
(1), bis(2-(4-methyl-2-oxoquinolin-1(2H)-yl)ethanoato)diphenyltin(IV) (2), and bis(2-(4-hydroxy-2-oxoquinolin1(2H)-yl)ethanoato)diphenyltin(IV) (3), were synthesized and characterized by elemental microanalysis, FT-IR
spectroscopy, and multinuclear (
1
H, 13C and 119Sn) NMR spectroscopy. Crystal structure of ligand precursor,
2-(4-methyl-2-oxoquinolinyl-1-(2H)-yl)acetic acid (HL2), has been determined by X-ray diffraction studies.
Asymmetric bidentate coordination of the carboxylato ligands and skew trapezoidal structures are assumed for
the synthesized complexes. In vitro anticancer activity of the synthesized diphenyltin(IV) complexes was evaluated against three human: MCF-7 (breast adenocarcinoma), A375 (melanoma), HCT116 (colorectal carcinoma),
and three mouse tumor cell lines: 4T1 (breast carcinoma), B16 (melanoma), CT26 (colon carcinoma) using MTT
and CV assays. The IC50 values fall in the range from 0.1 to 3.7 μM. Flow cytometric analysis and fluorescent
microscopy suggest that complex 1 induces caspase-dependent apoptosis followed with strong blockade of cell
division in HCT116 cells. Since complex 1 showed ROS/RNS scavenging potential mentioned cytotoxicity was
not connected with oxidative stress.",
publisher = "Elsevier Inc.",
journal = "Journal of Inorganic Biochemistry",
title = "Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies",
pages = "112399",
volume = "250",
doi = "10.1016/j.jinorgbio.2023.112399"
}

Kasalović, M. P., Jelača, S., Maksimović-Ivanić, D., Lađarević, J., Radovanović, L., Božić, B., Mijatović, S., Pantelić, N. Đ.,& Kaluđerović, G. N.. (2024). Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies. in Journal of Inorganic Biochemistry
Elsevier Inc.., 250, 112399.
https://doi.org/10.1016/j.jinorgbio.2023.112399

Kasalović MP, Jelača S, Maksimović-Ivanić D, Lađarević J, Radovanović L, Božić B, Mijatović S, Pantelić NĐ, Kaluđerović GN. Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies. in Journal of Inorganic Biochemistry. 2024;250:112399.
doi:10.1016/j.jinorgbio.2023.112399 .

Kasalović, Marijana P., Jelača, Sanja, Maksimović-Ivanić, Danijela, Lađarević, Jelena, Radovanović, Lidija, Božić, Bojan, Mijatović, Sanja, Pantelić, Nebojša Đ., Kaluđerović, Goran N., "Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies" in Journal of Inorganic Biochemistry, 250 (2024):112399,
https://doi.org/10.1016/j.jinorgbio.2023.112399 . .

TY  - JOUR
AU  - Kasalović, Marijana P.
AU  - Jelača, Sanja
AU  - Milanović, Žiko
AU  - Maksimović-Ivanić, Danijela
AU  - Mijatović, Sanja
AU  - Lađarević, Jelena
AU  - Božić, Bojan
AU  - Marković, Zoran
AU  - Dunđerović, Duško
AU  - Rüffer, Tobias
AU  - Kretschmer, Robert
AU  - Kaluđerović, Goran N.
AU  - Pantelić, Nebojša Đ.
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7458
AB  - Three newly synthesized triphenyltin(iv) compounds, Ph3SnL1 (L1− = 3-(4-methyl-2-oxoquinolin-1(2H)-yl)propanoato), Ph3SnL2 (L2− = 2-(4-methyl-2-oxoquinolin-1(2H)-yl)ethanoato), and Ph3SnL3 (L3− = 2-(4-hydroxy-2-oxoquinolin-1(2H)-yl)ethanoato), were characterized by elemental microanalysis, FT-IR spectroscopy and multinuclear (1H, 13C and 119Sn) NMR spectroscopy. A single X-ray diffraction study indicates that compounds Ph3SnL1 and Ph3SnL2 exhibit a 1D zig-zag chain polymeric structure, which in the case of Ph3SnL2 is additionally stabilized by π-interactions. In addition, the synthesized compounds were further examined using density functional theory and natural bond orbital analysis. The compounds have been evaluated for their in vitro anticancer activity against three human cell lines: MCF-7 (breast adenocarcinoma), A375 (melanoma), HCT116 (colorectal carcinoma), and three murine cell lines: 4T1 (breast carcinoma), B16 (melanoma), CT26 (colon carcinoma) using MTT and CV assays. The IC50 values fall in the nanomolar range, indicating that these compounds possess better anticancer activity than cisplatin. The study of the effect of the newly developed drug Ph3SnL1 showed its plasticity in achieving an antitumor effect in vitro, which depends on the specificity of the phenotype and the redox status of the malignant cell line and ranges from the initiation of apoptotic cell death to the induction of differentiation to a more mature cell form. In the syngeneic model of murine melanoma, Ph3SnL1 showed the potential to reduce the tumor volume similar to cisplatin, but in a well-tolerated form and with low systemic toxicity, representing a significant advantage over the conventional drug.
PB  - Royal Society of Chemistry
T2  - Dalton Transactions
T1  - Novel triphenyltin(iv) compounds with carboxylato N-functionalized 2-quinolones as promising potential anticancer drug candidates: in vitro and in vivo evaluation
DO  - 10.1039/D4DT00182F
ER  - 

@article{
author = "Kasalović, Marijana P. and Jelača, Sanja and Milanović, Žiko and Maksimović-Ivanić, Danijela and Mijatović, Sanja and Lađarević, Jelena and Božić, Bojan and Marković, Zoran and Dunđerović, Duško and Rüffer, Tobias and Kretschmer, Robert and Kaluđerović, Goran N. and Pantelić, Nebojša Đ.",
year = "2024",
abstract = "Three newly synthesized triphenyltin(iv) compounds, Ph3SnL1 (L1− = 3-(4-methyl-2-oxoquinolin-1(2H)-yl)propanoato), Ph3SnL2 (L2− = 2-(4-methyl-2-oxoquinolin-1(2H)-yl)ethanoato), and Ph3SnL3 (L3− = 2-(4-hydroxy-2-oxoquinolin-1(2H)-yl)ethanoato), were characterized by elemental microanalysis, FT-IR spectroscopy and multinuclear (1H, 13C and 119Sn) NMR spectroscopy. A single X-ray diffraction study indicates that compounds Ph3SnL1 and Ph3SnL2 exhibit a 1D zig-zag chain polymeric structure, which in the case of Ph3SnL2 is additionally stabilized by π-interactions. In addition, the synthesized compounds were further examined using density functional theory and natural bond orbital analysis. The compounds have been evaluated for their in vitro anticancer activity against three human cell lines: MCF-7 (breast adenocarcinoma), A375 (melanoma), HCT116 (colorectal carcinoma), and three murine cell lines: 4T1 (breast carcinoma), B16 (melanoma), CT26 (colon carcinoma) using MTT and CV assays. The IC50 values fall in the nanomolar range, indicating that these compounds possess better anticancer activity than cisplatin. The study of the effect of the newly developed drug Ph3SnL1 showed its plasticity in achieving an antitumor effect in vitro, which depends on the specificity of the phenotype and the redox status of the malignant cell line and ranges from the initiation of apoptotic cell death to the induction of differentiation to a more mature cell form. In the syngeneic model of murine melanoma, Ph3SnL1 showed the potential to reduce the tumor volume similar to cisplatin, but in a well-tolerated form and with low systemic toxicity, representing a significant advantage over the conventional drug.",
publisher = "Royal Society of Chemistry",
journal = "Dalton Transactions",
title = "Novel triphenyltin(iv) compounds with carboxylato N-functionalized 2-quinolones as promising potential anticancer drug candidates: in vitro and in vivo evaluation",
doi = "10.1039/D4DT00182F"
}

Kasalović, M. P., Jelača, S., Milanović, Ž., Maksimović-Ivanić, D., Mijatović, S., Lađarević, J., Božić, B., Marković, Z., Dunđerović, D., Rüffer, T., Kretschmer, R., Kaluđerović, G. N.,& Pantelić, N. Đ.. (2024). Novel triphenyltin(iv) compounds with carboxylato N-functionalized 2-quinolones as promising potential anticancer drug candidates: in vitro and in vivo evaluation. in Dalton Transactions
Royal Society of Chemistry..
https://doi.org/10.1039/D4DT00182F

Kasalović MP, Jelača S, Milanović Ž, Maksimović-Ivanić D, Mijatović S, Lađarević J, Božić B, Marković Z, Dunđerović D, Rüffer T, Kretschmer R, Kaluđerović GN, Pantelić NĐ. Novel triphenyltin(iv) compounds with carboxylato N-functionalized 2-quinolones as promising potential anticancer drug candidates: in vitro and in vivo evaluation. in Dalton Transactions. 2024;.
doi:10.1039/D4DT00182F .

Kasalović, Marijana P., Jelača, Sanja, Milanović, Žiko, Maksimović-Ivanić, Danijela, Mijatović, Sanja, Lađarević, Jelena, Božić, Bojan, Marković, Zoran, Dunđerović, Duško, Rüffer, Tobias, Kretschmer, Robert, Kaluđerović, Goran N., Pantelić, Nebojša Đ., "Novel triphenyltin(iv) compounds with carboxylato N-functionalized 2-quinolones as promising potential anticancer drug candidates: in vitro and in vivo evaluation" in Dalton Transactions (2024),
https://doi.org/10.1039/D4DT00182F . .