Analysis of metal ion release from biomedical implants
Apstrakt
Metallic biomaterials are commonly used for fixation or replacement of damaged bones in the human body due to their good combination of mechanical properties. The disadvantage of metals as implant materials is their susceptibility to corrosion and metal ion release, which can cause serious health problems. In certain concentrations metals and metal ions are toxic and their presence can cause diverse inflammatory reactions, genetic mutations or even cancer. In this paper, different approaches to metal ion release examination, from biometallic materials sample preparation to research results interpretation, will be presented. An overview of the analytical techniques, used for determination of the type and concentration of released ions from implants in simulated biofluids, is also given in the paper.
Ključne reči:
metallic implants / biofluid / corrosion / ion release / analytical techniquesIzvor:
Metallurgical & Materials Engineering, 2013, 19, 2, 167-176Izdavač:
- Association of Metallurgical Engineers of Serbia
Finansiranje / projekti:
- Razvoj novih inkapsulacionih i enzimskih tehnologija za proizvodnju biokatalizatora i biološki aktivnih komponenata hrane u cilju povećanja njene konkurentnosti, kvaliteta i bezbednosti (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46010)
- Mikromehanički kriterijumi oštećenja i loma (RS-MESTD-Basic Research (BR or ON)-174004)
Institucija/grupa
Tehnološko-metalurški fakultetTY - JOUR AU - Dimić, Ivana AU - Cvijović-Alagić, Ivana AU - Rakin, Marko AU - Bugarski, Branko PY - 2013 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2326 AB - Metallic biomaterials are commonly used for fixation or replacement of damaged bones in the human body due to their good combination of mechanical properties. The disadvantage of metals as implant materials is their susceptibility to corrosion and metal ion release, which can cause serious health problems. In certain concentrations metals and metal ions are toxic and their presence can cause diverse inflammatory reactions, genetic mutations or even cancer. In this paper, different approaches to metal ion release examination, from biometallic materials sample preparation to research results interpretation, will be presented. An overview of the analytical techniques, used for determination of the type and concentration of released ions from implants in simulated biofluids, is also given in the paper. PB - Association of Metallurgical Engineers of Serbia T2 - Metallurgical & Materials Engineering T1 - Analysis of metal ion release from biomedical implants EP - 176 IS - 2 SP - 167 VL - 19 UR - https://hdl.handle.net/21.15107/rcub_technorep_2326 ER -
@article{ author = "Dimić, Ivana and Cvijović-Alagić, Ivana and Rakin, Marko and Bugarski, Branko", year = "2013", abstract = "Metallic biomaterials are commonly used for fixation or replacement of damaged bones in the human body due to their good combination of mechanical properties. The disadvantage of metals as implant materials is their susceptibility to corrosion and metal ion release, which can cause serious health problems. In certain concentrations metals and metal ions are toxic and their presence can cause diverse inflammatory reactions, genetic mutations or even cancer. In this paper, different approaches to metal ion release examination, from biometallic materials sample preparation to research results interpretation, will be presented. An overview of the analytical techniques, used for determination of the type and concentration of released ions from implants in simulated biofluids, is also given in the paper.", publisher = "Association of Metallurgical Engineers of Serbia", journal = "Metallurgical & Materials Engineering", title = "Analysis of metal ion release from biomedical implants", pages = "176-167", number = "2", volume = "19", url = "https://hdl.handle.net/21.15107/rcub_technorep_2326" }
Dimić, I., Cvijović-Alagić, I., Rakin, M.,& Bugarski, B.. (2013). Analysis of metal ion release from biomedical implants. in Metallurgical & Materials Engineering Association of Metallurgical Engineers of Serbia., 19(2), 167-176. https://hdl.handle.net/21.15107/rcub_technorep_2326
Dimić I, Cvijović-Alagić I, Rakin M, Bugarski B. Analysis of metal ion release from biomedical implants. in Metallurgical & Materials Engineering. 2013;19(2):167-176. https://hdl.handle.net/21.15107/rcub_technorep_2326 .
Dimić, Ivana, Cvijović-Alagić, Ivana, Rakin, Marko, Bugarski, Branko, "Analysis of metal ion release from biomedical implants" in Metallurgical & Materials Engineering, 19, no. 2 (2013):167-176, https://hdl.handle.net/21.15107/rcub_technorep_2326 .