Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions
Само за регистроване кориснике
2019
Аутори
Davidović, SlađanaLazić, Vesna M.
Miljković, Miona
Gordić, Milan V.
Sekulić, Milica
Marinović-Cincović, Milena
Ratnayake, Ishara S.
Ahrenkiel, Scott Phillip
Nedeljković, Jovan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The antibacterial ability of in situ prepared nanometer-sized silver particles, immobilized in agar-agar films, was studied as a function of the concentration of co-dopant, magnesium ions. Content of inorganic components in hybrid films was determined using inductively coupled plasma optic emission spectroscopy, and found to be low ( lt 2 wt.-%). Morphology of prepared hybrid films, studied by transmission electron microscopy, revealed the presence of non-agglomerated and randomly distributed 10-20 nm silver nanoparticles (Ag NPs) within the agar-agar matrices. Fourier-transform infrared spectroscopy indicated the distinct chemical interaction between Ag NPs and polymer chains. Thermogravimetric analysis, as well as the determination of tensile strength, Young's modulus, and elongation at break showed improvement of thermal stability and mechanical properties of agar-agar matrices upon the incorporation of Ag NPs due to high compatibility between the hydrophilic organic component and... inorganic components. The complete microbial reduction of Gram-positive bacteria Staphylococcus aureus was observed for all agar-silver films, while satisfactory results were observed for Gram-negative bacteria Pseudomonas aeruginosa ( gt = 99.6%). The release of Ag+ ions is suppressed by the increase of the concentration of Mg2+ ions and it was found to be significantly smaller ( lt = 0.24 ppm) than the harmful ecological level (1 ppm).
Кључне речи:
Agar-agar / Silver nanoparticles / Nanocomposite films / Antimicrobial activityИзвор:
Carbohydrate Polymers, 2019, 224Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Материјали редуковане димензионалности за ефикасну апсорпцију светлости и конверзију енергије (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45020)
- Примена биотехнолошких метода у одрживом искоришћењу нус-производа агроиндустрије (RS-MESTD-Technological Development (TD or TR)-31035)
DOI: 10.1016/j.carbpol.2019.115187
ISSN: 0144-8617
PubMed: 31472840
WoS: 000484001200034
Scopus: 2-s2.0-85070631458
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Davidović, Slađana AU - Lazić, Vesna M. AU - Miljković, Miona AU - Gordić, Milan V. AU - Sekulić, Milica AU - Marinović-Cincović, Milena AU - Ratnayake, Ishara S. AU - Ahrenkiel, Scott Phillip AU - Nedeljković, Jovan PY - 2019 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4081 AB - The antibacterial ability of in situ prepared nanometer-sized silver particles, immobilized in agar-agar films, was studied as a function of the concentration of co-dopant, magnesium ions. Content of inorganic components in hybrid films was determined using inductively coupled plasma optic emission spectroscopy, and found to be low ( lt 2 wt.-%). Morphology of prepared hybrid films, studied by transmission electron microscopy, revealed the presence of non-agglomerated and randomly distributed 10-20 nm silver nanoparticles (Ag NPs) within the agar-agar matrices. Fourier-transform infrared spectroscopy indicated the distinct chemical interaction between Ag NPs and polymer chains. Thermogravimetric analysis, as well as the determination of tensile strength, Young's modulus, and elongation at break showed improvement of thermal stability and mechanical properties of agar-agar matrices upon the incorporation of Ag NPs due to high compatibility between the hydrophilic organic component and inorganic components. The complete microbial reduction of Gram-positive bacteria Staphylococcus aureus was observed for all agar-silver films, while satisfactory results were observed for Gram-negative bacteria Pseudomonas aeruginosa ( gt = 99.6%). The release of Ag+ ions is suppressed by the increase of the concentration of Mg2+ ions and it was found to be significantly smaller ( lt = 0.24 ppm) than the harmful ecological level (1 ppm). PB - Elsevier Sci Ltd, Oxford T2 - Carbohydrate Polymers T1 - Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions VL - 224 DO - 10.1016/j.carbpol.2019.115187 ER -
@article{ author = "Davidović, Slađana and Lazić, Vesna M. and Miljković, Miona and Gordić, Milan V. and Sekulić, Milica and Marinović-Cincović, Milena and Ratnayake, Ishara S. and Ahrenkiel, Scott Phillip and Nedeljković, Jovan", year = "2019", abstract = "The antibacterial ability of in situ prepared nanometer-sized silver particles, immobilized in agar-agar films, was studied as a function of the concentration of co-dopant, magnesium ions. Content of inorganic components in hybrid films was determined using inductively coupled plasma optic emission spectroscopy, and found to be low ( lt 2 wt.-%). Morphology of prepared hybrid films, studied by transmission electron microscopy, revealed the presence of non-agglomerated and randomly distributed 10-20 nm silver nanoparticles (Ag NPs) within the agar-agar matrices. Fourier-transform infrared spectroscopy indicated the distinct chemical interaction between Ag NPs and polymer chains. Thermogravimetric analysis, as well as the determination of tensile strength, Young's modulus, and elongation at break showed improvement of thermal stability and mechanical properties of agar-agar matrices upon the incorporation of Ag NPs due to high compatibility between the hydrophilic organic component and inorganic components. The complete microbial reduction of Gram-positive bacteria Staphylococcus aureus was observed for all agar-silver films, while satisfactory results were observed for Gram-negative bacteria Pseudomonas aeruginosa ( gt = 99.6%). The release of Ag+ ions is suppressed by the increase of the concentration of Mg2+ ions and it was found to be significantly smaller ( lt = 0.24 ppm) than the harmful ecological level (1 ppm).", publisher = "Elsevier Sci Ltd, Oxford", journal = "Carbohydrate Polymers", title = "Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions", volume = "224", doi = "10.1016/j.carbpol.2019.115187" }
Davidović, S., Lazić, V. M., Miljković, M., Gordić, M. V., Sekulić, M., Marinović-Cincović, M., Ratnayake, I. S., Ahrenkiel, S. P.,& Nedeljković, J.. (2019). Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions. in Carbohydrate Polymers Elsevier Sci Ltd, Oxford., 224. https://doi.org/10.1016/j.carbpol.2019.115187
Davidović S, Lazić VM, Miljković M, Gordić MV, Sekulić M, Marinović-Cincović M, Ratnayake IS, Ahrenkiel SP, Nedeljković J. Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions. in Carbohydrate Polymers. 2019;224. doi:10.1016/j.carbpol.2019.115187 .
Davidović, Slađana, Lazić, Vesna M., Miljković, Miona, Gordić, Milan V., Sekulić, Milica, Marinović-Cincović, Milena, Ratnayake, Ishara S., Ahrenkiel, Scott Phillip, Nedeljković, Jovan, "Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions" in Carbohydrate Polymers, 224 (2019), https://doi.org/10.1016/j.carbpol.2019.115187 . .