Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin
Abstract
The inclusion complexes of the selected, potentially biologically active, succinimides with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD) were prepared. The formation of the inclusion complexes of the investigated monophenyl and diphenyl succinimide derivatives was confirmed using attenuated total reflection (ATR) study. Their electrochemical behavior was examined by cyclic voltammetry (CV) and square wave voltammetry (SWV) in 0.05 M NaHCO3 on a gold electrode. The stability constants for compound 1 were determined by cyclic voltammetry and calculated as K-beta CD = 350.87 M-1 and K-HP(beta CD) = 250.67 M-1. The SWV measurements reveal well defined peak at potential E-p = similar to 60 mV and the higher currents at E-p for both inclusion complex of the succinimides compared to the free compounds. The impact of chlorine atom in the phenyl moiety of succinimide derivatives on the activity in electro oxidation reaction is presented. Among the studied suc...cinimides, according to SWV measurements, the most active is the monophenyl succinimide derivative (compound 1) in complex with beta CD. The difference of peak current of compound 1 + beta CD compared to compound 1 + HP beta CD and free compound is 6.3 and 35.2 mu A cm(-2), respectively.
Keywords:
Diphenylsuccinimide / threephenylsuccinimide / ATR analysis / inclusion complexes / voltammetrySource:
Acta Chimica Slovenica, 2019, 66, 1, 182-189Publisher:
- Slovensko Kemijsko Drustvo, Ljubljana
Funding / projects:
- Study of the Synthesis, Structure and Activity of Natural and Synthetic Organic Compounds (RS-MESTD-Basic Research (BR or ON)-172013)
- New approach in designing materials for energy conversion and energy storage systems (RS-MESTD-Basic Research (BR or ON)-172060)
DOI: 10.17344/acsi.2018.4767
ISSN: 1318-0207
WoS: 000459347100023
Scopus: 2-s2.0-85062351811
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Lović, Jelena AU - Avramov-Ivić, Milka AU - Božić, Bojan AU - Lađarević, Jelena AU - Mijin, Dušan PY - 2019 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4182 AB - The inclusion complexes of the selected, potentially biologically active, succinimides with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD) were prepared. The formation of the inclusion complexes of the investigated monophenyl and diphenyl succinimide derivatives was confirmed using attenuated total reflection (ATR) study. Their electrochemical behavior was examined by cyclic voltammetry (CV) and square wave voltammetry (SWV) in 0.05 M NaHCO3 on a gold electrode. The stability constants for compound 1 were determined by cyclic voltammetry and calculated as K-beta CD = 350.87 M-1 and K-HP(beta CD) = 250.67 M-1. The SWV measurements reveal well defined peak at potential E-p = similar to 60 mV and the higher currents at E-p for both inclusion complex of the succinimides compared to the free compounds. The impact of chlorine atom in the phenyl moiety of succinimide derivatives on the activity in electro oxidation reaction is presented. Among the studied succinimides, according to SWV measurements, the most active is the monophenyl succinimide derivative (compound 1) in complex with beta CD. The difference of peak current of compound 1 + beta CD compared to compound 1 + HP beta CD and free compound is 6.3 and 35.2 mu A cm(-2), respectively. PB - Slovensko Kemijsko Drustvo, Ljubljana T2 - Acta Chimica Slovenica T1 - Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin EP - 189 IS - 1 SP - 182 VL - 66 DO - 10.17344/acsi.2018.4767 ER -
@article{ author = "Lović, Jelena and Avramov-Ivić, Milka and Božić, Bojan and Lađarević, Jelena and Mijin, Dušan", year = "2019", abstract = "The inclusion complexes of the selected, potentially biologically active, succinimides with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD) were prepared. The formation of the inclusion complexes of the investigated monophenyl and diphenyl succinimide derivatives was confirmed using attenuated total reflection (ATR) study. Their electrochemical behavior was examined by cyclic voltammetry (CV) and square wave voltammetry (SWV) in 0.05 M NaHCO3 on a gold electrode. The stability constants for compound 1 were determined by cyclic voltammetry and calculated as K-beta CD = 350.87 M-1 and K-HP(beta CD) = 250.67 M-1. The SWV measurements reveal well defined peak at potential E-p = similar to 60 mV and the higher currents at E-p for both inclusion complex of the succinimides compared to the free compounds. The impact of chlorine atom in the phenyl moiety of succinimide derivatives on the activity in electro oxidation reaction is presented. Among the studied succinimides, according to SWV measurements, the most active is the monophenyl succinimide derivative (compound 1) in complex with beta CD. The difference of peak current of compound 1 + beta CD compared to compound 1 + HP beta CD and free compound is 6.3 and 35.2 mu A cm(-2), respectively.", publisher = "Slovensko Kemijsko Drustvo, Ljubljana", journal = "Acta Chimica Slovenica", title = "Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin", pages = "189-182", number = "1", volume = "66", doi = "10.17344/acsi.2018.4767" }
Lović, J., Avramov-Ivić, M., Božić, B., Lađarević, J.,& Mijin, D.. (2019). Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin. in Acta Chimica Slovenica Slovensko Kemijsko Drustvo, Ljubljana., 66(1), 182-189. https://doi.org/10.17344/acsi.2018.4767
Lović J, Avramov-Ivić M, Božić B, Lađarević J, Mijin D. Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin. in Acta Chimica Slovenica. 2019;66(1):182-189. doi:10.17344/acsi.2018.4767 .
Lović, Jelena, Avramov-Ivić, Milka, Božić, Bojan, Lađarević, Jelena, Mijin, Dušan, "Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrin" in Acta Chimica Slovenica, 66, no. 1 (2019):182-189, https://doi.org/10.17344/acsi.2018.4767 . .