Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential
Аутори
Drvenica, IvanaBlazevic, Ivica
Boskovic, Perica
Bratanic, Andre
Bugarski, Branko
Bilusic, Tea
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Encapsulation of sinigrin in liposomes with the proliposomal method was performed in order to evaluate the effect of this process on in vitro simulated digestion and antioxidant potential of sinigrin. The recovery of sinigrin after simulated gastric and duodenal digestion of its free and liposomal forms was determined with HPLC-UV using human digestive juices. The antioxidant potential of sinigrin and sinigrin-loaded liposomes was determined with the Rancimat test as their ability to prolong oxidative stability of edible oil. The efficiency of 62% was obtained by encapsulating sinigrin in liposomes. The values of mean diameter, polydispersity index and zeta potential showed satisfactory size uniformity and physical stability of the liposomes containing sinigrin. Liposomes were shown to inhibit the digestion of sinigrin in both human gastric and intestinal juices, clearly enabling its prolonged release. Moreover, sinigrin in the liposomal form significantly prolonged the induction time ...of edible oil oxidation compared to its free form. The results obtained are encouraging from the point of view of a possible incorporation of the sinigrin-loaded liposomes in real functional food systems or their use as nutraceuticals.
Кључне речи:
sinigrin / liposomes / oxidative stability / gastric digestion / duodenal digestion / antioxidant potentialИзвор:
Polish Journal of Food and Nutrition Sciences, 2021, 71, 4, 441-449
DOI: 10.31883/pjfns/143574
ISSN: 1230-0322
WoS: 000731417500007
Scopus: 2-s2.0-85122149290
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Drvenica, Ivana AU - Blazevic, Ivica AU - Boskovic, Perica AU - Bratanic, Andre AU - Bugarski, Branko AU - Bilusic, Tea PY - 2021 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4825 AB - Encapsulation of sinigrin in liposomes with the proliposomal method was performed in order to evaluate the effect of this process on in vitro simulated digestion and antioxidant potential of sinigrin. The recovery of sinigrin after simulated gastric and duodenal digestion of its free and liposomal forms was determined with HPLC-UV using human digestive juices. The antioxidant potential of sinigrin and sinigrin-loaded liposomes was determined with the Rancimat test as their ability to prolong oxidative stability of edible oil. The efficiency of 62% was obtained by encapsulating sinigrin in liposomes. The values of mean diameter, polydispersity index and zeta potential showed satisfactory size uniformity and physical stability of the liposomes containing sinigrin. Liposomes were shown to inhibit the digestion of sinigrin in both human gastric and intestinal juices, clearly enabling its prolonged release. Moreover, sinigrin in the liposomal form significantly prolonged the induction time of edible oil oxidation compared to its free form. The results obtained are encouraging from the point of view of a possible incorporation of the sinigrin-loaded liposomes in real functional food systems or their use as nutraceuticals. T2 - Polish Journal of Food and Nutrition Sciences T1 - Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential EP - 449 IS - 4 SP - 441 VL - 71 DO - 10.31883/pjfns/143574 ER -
@article{ author = "Drvenica, Ivana and Blazevic, Ivica and Boskovic, Perica and Bratanic, Andre and Bugarski, Branko and Bilusic, Tea", year = "2021", abstract = "Encapsulation of sinigrin in liposomes with the proliposomal method was performed in order to evaluate the effect of this process on in vitro simulated digestion and antioxidant potential of sinigrin. The recovery of sinigrin after simulated gastric and duodenal digestion of its free and liposomal forms was determined with HPLC-UV using human digestive juices. The antioxidant potential of sinigrin and sinigrin-loaded liposomes was determined with the Rancimat test as their ability to prolong oxidative stability of edible oil. The efficiency of 62% was obtained by encapsulating sinigrin in liposomes. The values of mean diameter, polydispersity index and zeta potential showed satisfactory size uniformity and physical stability of the liposomes containing sinigrin. Liposomes were shown to inhibit the digestion of sinigrin in both human gastric and intestinal juices, clearly enabling its prolonged release. Moreover, sinigrin in the liposomal form significantly prolonged the induction time of edible oil oxidation compared to its free form. The results obtained are encouraging from the point of view of a possible incorporation of the sinigrin-loaded liposomes in real functional food systems or their use as nutraceuticals.", journal = "Polish Journal of Food and Nutrition Sciences", title = "Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential", pages = "449-441", number = "4", volume = "71", doi = "10.31883/pjfns/143574" }
Drvenica, I., Blazevic, I., Boskovic, P., Bratanic, A., Bugarski, B.,& Bilusic, T.. (2021). Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential. in Polish Journal of Food and Nutrition Sciences, 71(4), 441-449. https://doi.org/10.31883/pjfns/143574
Drvenica I, Blazevic I, Boskovic P, Bratanic A, Bugarski B, Bilusic T. Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential. in Polish Journal of Food and Nutrition Sciences. 2021;71(4):441-449. doi:10.31883/pjfns/143574 .
Drvenica, Ivana, Blazevic, Ivica, Boskovic, Perica, Bratanic, Andre, Bugarski, Branko, Bilusic, Tea, "Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential" in Polish Journal of Food and Nutrition Sciences, 71, no. 4 (2021):441-449, https://doi.org/10.31883/pjfns/143574 . .