Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity
Само за регистроване кориснике
2022
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Chitosan/gelatin and chitosan/gelatin/zeolite films prepared by solvent casting method were impregnated with a mixture of thymol and carvacrol using a green solvent, supercritical carbon dioxide at 35 °C and 30 MPa, during 18 h. Proposed method enabled preparation of biocompatible and biodegradable blends with strong antioxidant and antibacterial activity, whereby amounts of loaded thymol/carvacrol mixture were in the range from 3.3-6%. After initial burst release, both types of films exhibited gradual release of bioactive compounds, with around 72 and 96% of impregnated thymol/carvacrol mixture released in water and PBS (pH 7.4) during tested period of 10 days, respectively. Results of water vapor transmission rate (> 76 gm-2 day-1) confirmed that prepared composites are suitable for wound dressing application. Thermal analysis showed superior properties of prepared thymol/carvacrol loaded films compared to control samples. In addition, mechanical and structural properties, as well as... solubility and swelling behavior of the obtained films were investigated in detail.
Кључне речи:
Biopolymer / Processing / scCO2 / Impregnation / ThymolИзвор:
Macromolecular Materials and Engineering, 2022, 307, 4, 1-13Издавач:
- Wiley
Финансирање / пројекти:
- info:eu-repo/grantAgreement/MESTD/inst-2020/200287/RS/ (-)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200135 (Универзитет у Београду, Технолошко-металуршки факултет) (RS-MESTD-inst-2020-200135)
- Work was car-ried out in the frame of the COST-Action “Green Chemical EngineeringNetwork toward upscaling sustainable processes” (GREENERING, ref.CA18224) funded by the European Commission
Напомена:
- Peer reviewed manuscript: http://technorep.tmf.bg.ac.rs/handle/123456789/5085
Повезане информације:
- Верзија документа
http://technorep.tmf.bg.ac.rs/handle/123456789/5085
Колекције
Институција/група
Inovacioni centarTY - JOUR AU - Pajnik, Jelena AU - Dikić, Jelena AU - Milovanović, Stoja AU - Milošević, Milena AU - Jevtić, Sanja AU - Lukić, Ivana PY - 2022 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5086 AB - Chitosan/gelatin and chitosan/gelatin/zeolite films prepared by solvent casting method were impregnated with a mixture of thymol and carvacrol using a green solvent, supercritical carbon dioxide at 35 °C and 30 MPa, during 18 h. Proposed method enabled preparation of biocompatible and biodegradable blends with strong antioxidant and antibacterial activity, whereby amounts of loaded thymol/carvacrol mixture were in the range from 3.3-6%. After initial burst release, both types of films exhibited gradual release of bioactive compounds, with around 72 and 96% of impregnated thymol/carvacrol mixture released in water and PBS (pH 7.4) during tested period of 10 days, respectively. Results of water vapor transmission rate (> 76 gm-2 day-1) confirmed that prepared composites are suitable for wound dressing application. Thermal analysis showed superior properties of prepared thymol/carvacrol loaded films compared to control samples. In addition, mechanical and structural properties, as well as solubility and swelling behavior of the obtained films were investigated in detail. PB - Wiley T2 - Macromolecular Materials and Engineering T1 - Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity EP - 13 IS - 4 SP - 1 VL - 307 DO - 10.1002/mame.202200009 ER -
@article{ author = "Pajnik, Jelena and Dikić, Jelena and Milovanović, Stoja and Milošević, Milena and Jevtić, Sanja and Lukić, Ivana", year = "2022", abstract = "Chitosan/gelatin and chitosan/gelatin/zeolite films prepared by solvent casting method were impregnated with a mixture of thymol and carvacrol using a green solvent, supercritical carbon dioxide at 35 °C and 30 MPa, during 18 h. Proposed method enabled preparation of biocompatible and biodegradable blends with strong antioxidant and antibacterial activity, whereby amounts of loaded thymol/carvacrol mixture were in the range from 3.3-6%. After initial burst release, both types of films exhibited gradual release of bioactive compounds, with around 72 and 96% of impregnated thymol/carvacrol mixture released in water and PBS (pH 7.4) during tested period of 10 days, respectively. Results of water vapor transmission rate (> 76 gm-2 day-1) confirmed that prepared composites are suitable for wound dressing application. Thermal analysis showed superior properties of prepared thymol/carvacrol loaded films compared to control samples. In addition, mechanical and structural properties, as well as solubility and swelling behavior of the obtained films were investigated in detail.", publisher = "Wiley", journal = "Macromolecular Materials and Engineering", title = "Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity", pages = "13-1", number = "4", volume = "307", doi = "10.1002/mame.202200009" }
Pajnik, J., Dikić, J., Milovanović, S., Milošević, M., Jevtić, S.,& Lukić, I.. (2022). Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity. in Macromolecular Materials and Engineering Wiley., 307(4), 1-13. https://doi.org/10.1002/mame.202200009
Pajnik J, Dikić J, Milovanović S, Milošević M, Jevtić S, Lukić I. Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity. in Macromolecular Materials and Engineering. 2022;307(4):1-13. doi:10.1002/mame.202200009 .
Pajnik, Jelena, Dikić, Jelena, Milovanović, Stoja, Milošević, Milena, Jevtić, Sanja, Lukić, Ivana, "Zeolite/Chitosan/Gelatin Films: Preparation, SupercriticalCO2Processing, Characterization, and Bioactivity" in Macromolecular Materials and Engineering, 307, no. 4 (2022):1-13, https://doi.org/10.1002/mame.202200009 . .