Encapsulation of Rosa canina extract in liposomes produced by thin film method
Аутори
Jovanović, Aleksandra A.Balanč, Bojana
Trajković, Milica
Đorđević, Verica
Šavikin, Katarina
Živković, Jelena
Bugarski, Branko
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Rosa canina pseudo-fruit is rich in bioactive substances, such are carotenoids, ascorbic acid,
polyphenols, fatty acids and minerals. Because of its diuretic, anti-inflammatory, anti-allergic and
antioxidant properties it is frequently employed in traditional medicine. However, in order to
protect mentioned bioactive compounds and to improve its bioavailability and controlled release,
numerous encapsulation methods have been developed. Thus, R. canina ethanol extract obtained
using percolation at ambient temperature (25°C), was encapsulated into Lipoid G liposomes
produced in thin film procedure. Total polyphenol and flavonoid contents, as well as antioxidant
potential of the extract and extract loaded liposomes were determined. Encapsulation efficiency,
particle size, polydispersity index and zeta potential of the liposomes with extract were monitoring
during 30 days. Total polyphenol and flavonoid contents of the extract were 103.8±1.9 mg of gallic
acid equivalents/g of the... extract and 64.2±2.4 mg of catechin equivalents/g of the extract,
respectively; antioxidant potential of the extract was 15.3±2.1 mg of Trolox equivalents/g of the
extract (ABTS assay) and 1.07±0.01 mg/mL of the extract (DPPH assay). Total polyphenol and
flavonoid contents of the extract loaded liposomes were 0.316±0.023 mg of gallic acid
equivalents/mg of lipids and 0.219±0.009 mg of catechin equivalents/mg of lipids, respectively;
antioxidant potential of the sample was 0.134±0.004 mg of Trolox equivalents/mg of lipids (ABTS
assay) and 270.6±10.5 mg/mL of liposomal suspension (DPPH assay). Encapsulation efficiency
was the same during monitoring period and it was amounted 46.6±3.4%. Particle size and
polydispersity index of the liposomes with extract were increased from 618.2±10.9 to 1698.0±104.2
nm and from 0.441±0.007 to 0.589±0.011, respectively, during 30 days. On the other hand, zeta
potential of the extract loaded liposomes was decreased from -10.24±0.95 to -7.21±0.77 mV. R.
canina extract loaded liposomes developed in this study have potential to be used in food,
pharmacological and cosmetic industries due to beneficial health effects of R. canina active
compounds encapsulated into liposomes.
Кључне речи:
encapsulation efficiency / liposomes / Rosa canina / thin film methodИзвор:
2nd International UNIfood Conference, 2021, -176Издавач:
- University of Belgrade
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200287 (Иновациони центар Технолошко-металуршког факултета у Београду доо) (RS-MESTD-inst-2020-200287)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200135 (Универзитет у Београду, Технолошко-металуршки факултет) (RS-MESTD-inst-2020-200135)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200003 (Институт за проучавање лековитог биља 'Др Јосиф Панчић', Београд) (RS-MESTD-inst-2020-200003)
Колекције
Институција/група
Inovacioni centarTY - CONF AU - Jovanović, Aleksandra A. AU - Balanč, Bojana AU - Trajković, Milica AU - Đorđević, Verica AU - Šavikin, Katarina AU - Živković, Jelena AU - Bugarski, Branko PY - 2021 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6411 AB - Rosa canina pseudo-fruit is rich in bioactive substances, such are carotenoids, ascorbic acid, polyphenols, fatty acids and minerals. Because of its diuretic, anti-inflammatory, anti-allergic and antioxidant properties it is frequently employed in traditional medicine. However, in order to protect mentioned bioactive compounds and to improve its bioavailability and controlled release, numerous encapsulation methods have been developed. Thus, R. canina ethanol extract obtained using percolation at ambient temperature (25°C), was encapsulated into Lipoid G liposomes produced in thin film procedure. Total polyphenol and flavonoid contents, as well as antioxidant potential of the extract and extract loaded liposomes were determined. Encapsulation efficiency, particle size, polydispersity index and zeta potential of the liposomes with extract were monitoring during 30 days. Total polyphenol and flavonoid contents of the extract were 103.8±1.9 mg of gallic acid equivalents/g of the extract and 64.2±2.4 mg of catechin equivalents/g of the extract, respectively; antioxidant potential of the extract was 15.3±2.1 mg of Trolox equivalents/g of the extract (ABTS assay) and 1.07±0.01 mg/mL of the extract (DPPH assay). Total polyphenol and flavonoid contents of the extract loaded liposomes were 0.316±0.023 mg of gallic acid equivalents/mg of lipids and 0.219±0.009 mg of catechin equivalents/mg of lipids, respectively; antioxidant potential of the sample was 0.134±0.004 mg of Trolox equivalents/mg of lipids (ABTS assay) and 270.6±10.5 mg/mL of liposomal suspension (DPPH assay). Encapsulation efficiency was the same during monitoring period and it was amounted 46.6±3.4%. Particle size and polydispersity index of the liposomes with extract were increased from 618.2±10.9 to 1698.0±104.2 nm and from 0.441±0.007 to 0.589±0.011, respectively, during 30 days. On the other hand, zeta potential of the extract loaded liposomes was decreased from -10.24±0.95 to -7.21±0.77 mV. R. canina extract loaded liposomes developed in this study have potential to be used in food, pharmacological and cosmetic industries due to beneficial health effects of R. canina active compounds encapsulated into liposomes. PB - University of Belgrade C3 - 2nd International UNIfood Conference T1 - Encapsulation of Rosa canina extract in liposomes produced by thin film method EP - 176 UR - https://hdl.handle.net/21.15107/rcub_technorep_6411 ER -
@conference{ author = "Jovanović, Aleksandra A. and Balanč, Bojana and Trajković, Milica and Đorđević, Verica and Šavikin, Katarina and Živković, Jelena and Bugarski, Branko", year = "2021", abstract = "Rosa canina pseudo-fruit is rich in bioactive substances, such are carotenoids, ascorbic acid, polyphenols, fatty acids and minerals. Because of its diuretic, anti-inflammatory, anti-allergic and antioxidant properties it is frequently employed in traditional medicine. However, in order to protect mentioned bioactive compounds and to improve its bioavailability and controlled release, numerous encapsulation methods have been developed. Thus, R. canina ethanol extract obtained using percolation at ambient temperature (25°C), was encapsulated into Lipoid G liposomes produced in thin film procedure. Total polyphenol and flavonoid contents, as well as antioxidant potential of the extract and extract loaded liposomes were determined. Encapsulation efficiency, particle size, polydispersity index and zeta potential of the liposomes with extract were monitoring during 30 days. Total polyphenol and flavonoid contents of the extract were 103.8±1.9 mg of gallic acid equivalents/g of the extract and 64.2±2.4 mg of catechin equivalents/g of the extract, respectively; antioxidant potential of the extract was 15.3±2.1 mg of Trolox equivalents/g of the extract (ABTS assay) and 1.07±0.01 mg/mL of the extract (DPPH assay). Total polyphenol and flavonoid contents of the extract loaded liposomes were 0.316±0.023 mg of gallic acid equivalents/mg of lipids and 0.219±0.009 mg of catechin equivalents/mg of lipids, respectively; antioxidant potential of the sample was 0.134±0.004 mg of Trolox equivalents/mg of lipids (ABTS assay) and 270.6±10.5 mg/mL of liposomal suspension (DPPH assay). Encapsulation efficiency was the same during monitoring period and it was amounted 46.6±3.4%. Particle size and polydispersity index of the liposomes with extract were increased from 618.2±10.9 to 1698.0±104.2 nm and from 0.441±0.007 to 0.589±0.011, respectively, during 30 days. On the other hand, zeta potential of the extract loaded liposomes was decreased from -10.24±0.95 to -7.21±0.77 mV. R. canina extract loaded liposomes developed in this study have potential to be used in food, pharmacological and cosmetic industries due to beneficial health effects of R. canina active compounds encapsulated into liposomes.", publisher = "University of Belgrade", journal = "2nd International UNIfood Conference", title = "Encapsulation of Rosa canina extract in liposomes produced by thin film method", pages = "176", url = "https://hdl.handle.net/21.15107/rcub_technorep_6411" }
Jovanović, A. A., Balanč, B., Trajković, M., Đorđević, V., Šavikin, K., Živković, J.,& Bugarski, B.. (2021). Encapsulation of Rosa canina extract in liposomes produced by thin film method. in 2nd International UNIfood Conference University of Belgrade.. https://hdl.handle.net/21.15107/rcub_technorep_6411
Jovanović AA, Balanč B, Trajković M, Đorđević V, Šavikin K, Živković J, Bugarski B. Encapsulation of Rosa canina extract in liposomes produced by thin film method. in 2nd International UNIfood Conference. 2021;:null-176. https://hdl.handle.net/21.15107/rcub_technorep_6411 .
Jovanović, Aleksandra A., Balanč, Bojana, Trajković, Milica, Đorđević, Verica, Šavikin, Katarina, Živković, Jelena, Bugarski, Branko, "Encapsulation of Rosa canina extract in liposomes produced by thin film method" in 2nd International UNIfood Conference (2021), https://hdl.handle.net/21.15107/rcub_technorep_6411 .