TY  - JOUR
AU  - Milovanović, Ivan
AU  - Chillon, Thilo Samson
AU  - Hackler, Julian
AU  - Schomburg, Lutz
AU  - Goessler, Walter
AU  - Lajin, Bassam
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6910
AB  - Selenium (Se) is an essential trace element for human health, but its nutritional supply is insufficient in large parts of the world. Mushrooms can be enriched in selenium and can serve as alternative and natural source of selenium supplementation. In the present study, two common mushroom species (Pleurotus ostreatus and Ganoderma lucidum), were enriched with two selenium compounds (selenite and selenate) to test their suitability as natural sources of selenium supplementation. Sharp differences in the the metabolic patterns of the fortified selenium were observed. Selenium was effectively metabolized in P. ostreatus but remained in inorganic form in G. lucidum. However, mushrooms extracts were effective in enhancing selenoprotein expression in cell lines. The present study highlights the importance of employing selenium speciation analysis with an element-selective technique to examine the metabolic products following mushroom fortification for nutritional purposes due to the different toxicological profile and bioavailability of different selenium biotransformation products.
PB  - Elsevier Ltd.
T2  - Food Chemistry
T1  - Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation
SP  - 137842
VL  - 437
DO  - 10.1016/j.foodchem.2023.137842
ER  - 

@article{
author = "Milovanović, Ivan and Chillon, Thilo Samson and Hackler, Julian and Schomburg, Lutz and Goessler, Walter and Lajin, Bassam",
year = "2024",
abstract = "Selenium (Se) is an essential trace element for human health, but its nutritional supply is insufficient in large parts of the world. Mushrooms can be enriched in selenium and can serve as alternative and natural source of selenium supplementation. In the present study, two common mushroom species (Pleurotus ostreatus and Ganoderma lucidum), were enriched with two selenium compounds (selenite and selenate) to test their suitability as natural sources of selenium supplementation. Sharp differences in the the metabolic patterns of the fortified selenium were observed. Selenium was effectively metabolized in P. ostreatus but remained in inorganic form in G. lucidum. However, mushrooms extracts were effective in enhancing selenoprotein expression in cell lines. The present study highlights the importance of employing selenium speciation analysis with an element-selective technique to examine the metabolic products following mushroom fortification for nutritional purposes due to the different toxicological profile and bioavailability of different selenium biotransformation products.",
publisher = "Elsevier Ltd.",
journal = "Food Chemistry",
title = "Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation",
pages = "137842",
volume = "437",
doi = "10.1016/j.foodchem.2023.137842"
}

Milovanović, I., Chillon, T. S., Hackler, J., Schomburg, L., Goessler, W.,& Lajin, B.. (2024). Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation. in Food Chemistry
Elsevier Ltd.., 437, 137842.
https://doi.org/10.1016/j.foodchem.2023.137842

Milovanović I, Chillon TS, Hackler J, Schomburg L, Goessler W, Lajin B. Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation. in Food Chemistry. 2024;437:137842.
doi:10.1016/j.foodchem.2023.137842 .

Milovanović, Ivan, Chillon, Thilo Samson, Hackler, Julian, Schomburg, Lutz, Goessler, Walter, Lajin, Bassam, "Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation" in Food Chemistry, 437 (2024):137842,
https://doi.org/10.1016/j.foodchem.2023.137842 . .

TY  - JOUR
AU  - Milovanović, Ivan
AU  - Lajin, Bassam
AU  - Braeuer, Simone
AU  - Steiner, Oliver
AU  - Lisa, Fasshold
AU  - Goessler, Walter
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4334
AB  - Selenium (Se) and sulfur (S) speciation analysis in edible and medicinal Se enriched P. pulmonarius extracts was performed. Mycelium, colonized substrate, and fruiting bodies at different harvesting times were analyzed using ion-pairing reversed-phase chromatography coupled to an ICPMS/MS detector. Extraction efficiencies in en-zymatically digested and aqueous extracts were between 45.3 and 109% for Se, depending on the sample type. Selenomethionine (Se-Met) was found to be the major Se-compound, together with a number of unknown Se-species. Cystine (Cys(2)), methionine (Met), and sulfate were also detected and quantified in all samples. Most of the Se-Met (84.0%) and met (75.8%) were found to be in free form in the fruiting body, in contrast with the mycelium where 53.4% of Se-Met and 80.5% of met is incorporated into proteins.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Simultaneous selenium and sulfur speciation analysis in cultivated Pleurotus pulmonarius mushroom
EP  - 236
SP  - 231
VL  - 279
DO  - 10.1016/j.foodchem.2018.12.009
ER  - 

@article{
author = "Milovanović, Ivan and Lajin, Bassam and Braeuer, Simone and Steiner, Oliver and Lisa, Fasshold and Goessler, Walter",
year = "2019",
abstract = "Selenium (Se) and sulfur (S) speciation analysis in edible and medicinal Se enriched P. pulmonarius extracts was performed. Mycelium, colonized substrate, and fruiting bodies at different harvesting times were analyzed using ion-pairing reversed-phase chromatography coupled to an ICPMS/MS detector. Extraction efficiencies in en-zymatically digested and aqueous extracts were between 45.3 and 109% for Se, depending on the sample type. Selenomethionine (Se-Met) was found to be the major Se-compound, together with a number of unknown Se-species. Cystine (Cys(2)), methionine (Met), and sulfate were also detected and quantified in all samples. Most of the Se-Met (84.0%) and met (75.8%) were found to be in free form in the fruiting body, in contrast with the mycelium where 53.4% of Se-Met and 80.5% of met is incorporated into proteins.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Simultaneous selenium and sulfur speciation analysis in cultivated Pleurotus pulmonarius mushroom",
pages = "236-231",
volume = "279",
doi = "10.1016/j.foodchem.2018.12.009"
}

Milovanović, I., Lajin, B., Braeuer, S., Steiner, O., Lisa, F.,& Goessler, W.. (2019). Simultaneous selenium and sulfur speciation analysis in cultivated Pleurotus pulmonarius mushroom. in Food Chemistry
Elsevier Sci Ltd, Oxford., 279, 231-236.
https://doi.org/10.1016/j.foodchem.2018.12.009

Milovanović I, Lajin B, Braeuer S, Steiner O, Lisa F, Goessler W. Simultaneous selenium and sulfur speciation analysis in cultivated Pleurotus pulmonarius mushroom. in Food Chemistry. 2019;279:231-236.
doi:10.1016/j.foodchem.2018.12.009 .

Milovanović, Ivan, Lajin, Bassam, Braeuer, Simone, Steiner, Oliver, Lisa, Fasshold, Goessler, Walter, "Simultaneous selenium and sulfur speciation analysis in cultivated Pleurotus pulmonarius mushroom" in Food Chemistry, 279 (2019):231-236,
https://doi.org/10.1016/j.foodchem.2018.12.009 . .