Immobilized lipases as practical catalysts
Imobilisane lipaze kao katalizatori
dc.creator | Knežević, Zorica | |
dc.date.accessioned | 2021-03-10T10:30:44Z | |
dc.date.available | 2021-03-10T10:30:44Z | |
dc.date.issued | 2006 | |
dc.identifier.issn | 0440-6826 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/895 | |
dc.description.abstract | Attractive features of lipase systems include versatility, substrate selectivity, regioselectivity, enantioselectivity and catalysis at ambient temperatures and pressures. To fully exploit the technical and economical advantages of lipases, it is recommended to use them in an immobilized form to reduce the cost and the poor stability of the free lipase. The design of an efficient lipase immobilized system is rather difficult task. The selection criteria for immobilization technique and carrier is largely dependent on the particular lipase type, the type of reaction system (aqueous, organic solvent or two-phase system), the process conditions and the goal of immobilization. Furthermore, these will then determine desirable bioreactor design (batch, stirred tank, membrane reactor, column and plug-flow). In the search for novel materials and immobilization procedures it is essential to carry out fundamental work on the physicochemical factors affecting the activity and stability of immobilized lipases. This information is essential to further reactor development and industrial scale-up. Several attractive concepts for lipase immobilization and bioreactor designs for lipase catalyzed process have been developed over the last decade. Mostly used systems are based on lipase adsorbed or covalently attached to solid supports, or entrapped in gel matrices in packed and fluidized bed reactors. Membrane reactor with lipase immobilized in the pore of membranes is another promising approach to many lipase catalyzed processes. This system may help in the future to integrate the bioprocess with downstream processing with an effort to increase the productivity while minimizing product recovery cost. Immobilized lipase technology may also be useful in no aqueous media, not only in terms of stabilization of the biocatalysts but also in the development of continuous bioreactors. The use of immobilized lipases would be especially useful for specific applications in the pharmaceutical, oleochemical and food industry. | en |
dc.publisher | Srpsko hemijsko društvo, Beograd | |
dc.rights | openAccess | |
dc.source | Hemijski pregled | |
dc.subject | Lipases | |
dc.subject | immobilization | |
dc.subject | adsorption | |
dc.subject | covalent immobilization | |
dc.subject | entrapment | |
dc.subject | hydrogel beads | |
dc.subject | membrane reactor | |
dc.title | Immobilized lipases as practical catalysts | en |
dc.title | Imobilisane lipaze kao katalizatori | sr |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.epage | 18 | |
dc.citation.issue | 1 | |
dc.citation.other | 47(1): 10-18 | |
dc.citation.spage | 10 | |
dc.citation.volume | 47 | |
dc.identifier.fulltext | http://TechnoRep.tmf.bg.ac.rs/bitstream/id/11102/bitstream_11102.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_technorep_895 | |
dc.type.version | publishedVersion |